Topoisomerase II- and Condensin-Dependent Breakage of MEC1ATR-Sensitive Fragile Sites Occurs Independently of Spindle Tension, Anaphase, or Cytokinesis

PLoS Genetics

Volumn 8, Issue 10, 2012, Pages

  Hashash, Nadia ^a   Johnson, Anthony L ^a   Cha, Rita S ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CONDENSIN; DNA TOPOISOMERASE (ATP HYDROLYSING); PROTEIN MEC1; RAD52 PROTEIN; UNCLASSIFIED DRUG;

ANAPHASE; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL STRESS; CELLULAR PARAMETERS; CHROMOSOME BREAKAGE; CHROMOSOME CONDENSATION; CHROMOSOME FRAGILE SITE; CHROMOSOME REPLICATION; CONTROLLED STUDY; CYTOKINESIS; DNA DAMAGE; FUNGAL GENE; GENETIC EPISTASIS; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; MMS4 GENE; MOLECULAR PATHOLOGY; MUS81 GENE; NONHUMAN; NULL ALLELE; RAD52 GENE; REPLICATION SLOW ZONE; SGS1 GENE; SPINDLE TENSION; SRS2 GENE; TOP3 GENE; TOPOISOMERASE II GENE; YCG1 GENE; YEAST; YSC4 GENE;

ADENOSINE TRIPHOSPHATASES; ANAPHASE; CHROMOSOME BREAKAGE; CHROMOSOME FRAGILE SITES; CYTOKINESIS; DNA REPLICATION; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOSIS; MITOTIC SPINDLE APPARATUS; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE PROTEINS; SACCHAROMYCETALES;

MAMMALIA; SACCHAROMYCETALES;

EID: 84868091320     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002978     Document Type: Article

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