AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants

PLoS Genetics

Volumn 7, Issue 2, 2011, Pages

  Ruiz, José F ^a   Gómez González, Belén ^a   Aguilera, Andrés ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; IMMUNOGLOBULIN; MYC PROTEIN; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE;

ARTICLE; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; FUNGAL STRAIN; FUNGUS MUTANT; GENETIC RECOMBINATION; GENETIC STABILITY; IMMUNOGLOBULIN GENE; NONHUMAN; PLASMID; SACCHAROMYCES CEREVISIAE; WILD TYPE; ANIMAL; CHROMOSOME; ENZYMOLOGY; GENE TRANSLOCATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; NUCLEOTIDE SEQUENCE; SEQUENCE ALIGNMENT;

MAMMALIA; SACCHAROMYCES CEREVISIAE;

ANIMALS; BASE SEQUENCE; CHROMOSOMES, FUNGAL; CYTIDINE DEAMINASE; DNA BREAKS, DOUBLE-STRANDED; HUMANS; IMMUNOGLOBULIN SWITCH REGION; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PROTO-ONCOGENE PROTEINS C-MYC; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; TRANSLOCATION, GENETIC;

EID: 79952266545     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002009     Document Type: Article

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