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Volumn 30, Issue 19, 2011, Pages 4033-4046

G-quadruplex-induced instability during leading-strand replication

Author keywords

[No Author keywords available]

Indexed keywords

CEB1 PROTEIN; GUANINE QUADRUPLEX; PIF1 HELICASE; RAD51 PROTEIN; RAD52 PROTEIN; REV1 POLYMERASE; SACCHAROMYCES CEREVISIAE PROTEIN; UNCLASSIFIED DRUG;

EID: 80053611613     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.316     Document Type: Article
Times cited : (258)

References (58)
  • 1
    • 39449096135 scopus 로고    scopus 로고
    • Genome instability: A mechanistic view of its causes and consequences
    • DOI 10.1038/nrg2268, PII NRG2268
    • Aguilera A, Gomez-Gonzalez B (2008) Genome instability: a mechanistic view of its causes and consequences. Nat Rev Genet 9: 204-217 (Pubitemid 351271797)
    • (2008) Nature Reviews Genetics , vol.9 , Issue.3 , pp. 204-217
    • Aguilera, A.1    Gomez-Gonzalez, B.2
  • 2
    • 33751237066 scopus 로고    scopus 로고
    • The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes
    • DOI 10.1101/gad.1478906
    • Azvolinsky A, Dunaway S, Torres JZ, Bessler JB, Zakian VA (2006) The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes. Genes Dev 20: 3104-3116 (Pubitemid 44790626)
    • (2006) Genes and Development , vol.20 , Issue.22 , pp. 3104-3116
    • Azvolinsky, A.1    Dunaway, S.2    Torres, J.Z.3    Bessler, J.B.4    Zakian, V.A.5
  • 4
    • 27744445335 scopus 로고    scopus 로고
    • The yeast Pif1p helicase removes telomerase from telomeric DNA
    • DOI 10.1038/nature04091, PII N04091
    • Boulé JB, Vega LR, Zakian VA (2005) The yeast Pif1p helicase removes telomerase from telomeric DNA. Nature 438: 57-61 (Pubitemid 41599817)
    • (2005) Nature , vol.438 , Issue.7064 , pp. 57-61
    • Boule, J.-B.1    Vega, L.R.2    Zakian, V.A.3
  • 5
    • 0023646792 scopus 로고
    • The localization of replication origins on ARS plasmids in S. cerevisiae
    • Brewer BJ, Fangman WL (1987) The localization of replication origins on ARS plasmids in S. cerevisiae. Cell 51: 463-471
    • (1987) Cell , vol.51 , pp. 463-471
    • Brewer, B.J.1    Fangman, W.L.2
  • 6
    • 33645215616 scopus 로고    scopus 로고
    • Evidence suggesting that Pif1 Helicase functions in DNA replication with the Dna2 Helicase/Nuclease and DNA Polymerase q
    • Budd ME, Reis CC, Smith S, Myung K, Campbell JL (2006) Evidence suggesting that Pif1 Helicase functions in DNA replication with the Dna2 Helicase/Nuclease and DNA Polymerase q. Mol Cell Biol 26: 2490-2500
    • (2006) Mol Cell Biol , vol.26 , pp. 2490-2500
    • Budd, M.E.1    Reis, C.C.2    Smith, S.3    Myung, K.4    Campbell, J.L.5
  • 8
    • 77950862944 scopus 로고    scopus 로고
    • Double Holliday junctions are intermediates of DNA break repair
    • Bzymek M, Thayer NH, Oh SD, Kleckner N, Hunter N (2010) Double Holliday junctions are intermediates of DNA break repair. Nature 464: 937-941
    • (2010) Nature , vol.464 , pp. 937-941
    • Bzymek, M.1    Thayer, N.H.2    Oh, S.D.3    Kleckner, N.4    Hunter, N.5
  • 9
    • 68449102464 scopus 로고    scopus 로고
    • An alternative DNA structure is necessary for pilin antigenic variation in Neisseria gonorrhoeae
    • Cahoon LA, Seifert HS (2009) An alternative DNA structure is necessary for pilin antigenic variation in Neisseria gonorrhoeae. Science 325: 764-767
    • (2009) Science , vol.325 , pp. 764-767
    • Cahoon, L.A.1    Seifert, H.S.2
  • 10
    • 72449150129 scopus 로고    scopus 로고
    • Telomerase is essential to alleviate pif1-induced replication stress at telomeres
    • Chang M, Luke B, Kraft C, Li Z, Peter M, Lingner J, Rothstein R (2009) Telomerase is essential to alleviate pif1-induced replication stress at telomeres. Genetics 183: 779-791
    • (2009) Genetics , vol.183 , pp. 779-791
    • Chang, M.1    Luke, B.2    Kraft, C.3    Li, Z.4    Peter, M.5    Lingner, J.6    Rothstein, R.7
  • 11
    • 79961029908 scopus 로고    scopus 로고
    • DNA secondary structures and epigenetic determinants of cancer genome evolution
    • De S, Michor F (2011) DNA secondary structures and epigenetic determinants of cancer genome evolution. Nat Struct Mol Biol 18: 950-955
    • (2011) Nat Struct Mol Biol , vol.18 , pp. 950-955
    • De, S.1    Michor, F.2
  • 12
    • 37049004147 scopus 로고    scopus 로고
    • Targeting telomeres and telomerase
    • DOI 10.1016/j.biochi.2007.07.011, PII S0300908407001873, Telomeres and Telomerase: from Basic Research to Clinical Applications
    • De Cian A, Lacroix L, Douarre C, Temime-Smaali N, Trentesaux C, Riou JF, Mergny JL (2008) Targeting telomeres and telomerase. Biochimie 90: 131-155 (Pubitemid 350245369)
    • (2008) Biochimie , vol.90 , Issue.1 , pp. 131-155
    • De Cian, A.1    Lacroix, L.2    Douarre, C.3    Temime-Smaali, N.4    Trentesaux, C.5    Riou, J.-F.6    Mergny, J.-L.7
  • 15
    • 0027278767 scopus 로고
    • A tetrameric DNA structure with protonated cytosine·cytosine base pairs
    • DOI 10.1038/363561a0
    • Gehring K, Leroy JL, Gueron M (1993) A tetrameric DNA structure with protonated cytosine.cytosine base pairs. Nature 363: 561-565 (Pubitemid 23186646)
    • (1993) Nature , vol.363 , Issue.6429 , pp. 561-565
    • Gehring, K.1    Leroy, J.-L.2    Gueron, M.3
  • 16
  • 17
    • 31844456472 scopus 로고    scopus 로고
    • Replication fork reactivation downstream of a blocked nascent leading strand
    • DOI 10.1038/nature04329, PII NATURE04329
    • Heller RC, Marians KJ (2006) Replication fork reactivation downstream of a blocked nascent leading strand. Nature 439: 557-562 (Pubitemid 43185374)
    • (2006) Nature , vol.439 , Issue.7076 , pp. 557-562
    • Heller, R.C.1    Marians, K.J.2
  • 18
    • 33748713412 scopus 로고    scopus 로고
    • Rad54: The Swiss Army knife of homologous recombination?
    • DOI 10.1093/nar/gkl481
    • Heyer WD, Li X, Rolfsmeier M, Zhang XP (2006) Rad54: the Swiss Army knife of homologous recombination? Nucleic Acids Res 34: 4115-4125 (Pubitemid 44542190)
    • (2006) Nucleic Acids Research , vol.34 , Issue.15 , pp. 4115-4125
    • Heyer, W.-D.1    Li, X.2    Rolfsmeier, M.3    Zhang, X.-P.4
  • 19
    • 20144364292 scopus 로고    scopus 로고
    • Prevalence of quadruplexes in the human genome
    • DOI 10.1093/nar/gki609
    • Huppert JL, Balasubramanian S (2005) Prevalence of quadruplexes in the human genome. Nucleic Acids Res 33: 2908-2916 (Pubitemid 41511230)
    • (2005) Nucleic Acids Research , vol.33 , Issue.9 , pp. 2908-2916
    • Huppert, J.L.1    Balasubramanian, S.2
  • 20
    • 0348047594 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Helicase Rrm3p Facilitates Replication Past Nonhistone Protein-DNA Complexes
    • DOI 10.1016/S1097-2765(03)00456-8
    • Ivessa AS, Lenzmeier BA, Bessler JB, Goudsouzian LK, Schnakenberg SL, Zakian VA (2003) The Saccharomyces cerevi-siae helicase Rrm3p facilitates replication past nonhistone pro-tein-DNA complexes. Mol Cell 12: 1525-1536 (Pubitemid 38037020)
    • (2003) Molecular Cell , vol.12 , Issue.6 , pp. 1525-1536
    • Ivessa, A.S.1    Lenzmeier, B.A.2    Bessler, J.B.3    Goudsouzian, L.K.4    Schnakenberg, S.L.5    Zakian, V.A.6
  • 21
    • 45449102827 scopus 로고    scopus 로고
    • Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans
    • Kruisselbrink E, Guryev V, Brouwer K, Pontier DB, Cuppen E, Tijsterman M (2008) Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans. Curr Biol 18: 900-905
    • (2008) Curr Biol , vol.18 , pp. 900-905
    • Kruisselbrink, E.1    Guryev, V.2    Brouwer, K.3    Pontier, D.B.4    Cuppen, E.5    Tijsterman, M.6
  • 22
    • 54249092768 scopus 로고    scopus 로고
    • Dividing the workload at a eukar-yotic replication fork
    • Kunkel TA, Burgers PM (2008) Dividing the workload at a eukar-yotic replication fork. Trends Cell Biol 18: 521-527
    • (2008) Trends Cell Biol , vol.18 , pp. 521-527
    • Kunkel, T.A.1    Burgers, P.M.2
  • 24
    • 0037124348 scopus 로고    scopus 로고
    • Instability of the human minisatellite CEB1 in rad27Δ and dna2-1 replication-deficient yeast cells
    • DOI 10.1093/emboj/cdf310
    • Lopes J, Debrauwere H, Buard J, Nicolas A (2002) Instability of the human minisatellite CEB1 in rad27D and dna2-1 replication-deficient yeast cells. EMBO J 21: 3201-3211 (Pubitemid 34670403)
    • (2002) EMBO Journal , vol.21 , Issue.12 , pp. 3201-3211
    • Lopes, J.1    Debrauwere, H.2    Buard, J.3    Nicolas, A.4
  • 25
    • 33747771700 scopus 로고    scopus 로고
    • Complex minisatellite rearrangements generated in the total or partial absence of Rad27/hFEN1 activity occur in a single generation and are Rad51 and Rad52 dependent
    • DOI 10.1128/MCB.00649-06
    • Lopes J, Ribeyre C, Nicolas A (2006a) Complex minisatellite rearrangements generated in the total or partial absence of Rad27/hFEN1 activity occur in a single generation and are Rad51 and Rad52 dependent. Mol Cell Biol 26: 6675-6689 (Pubitemid 44277902)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.17 , pp. 6675-6689
    • Lopes, J.1    Ribeyre, C.2    Nicolas, A.3
  • 26
    • 0347416973 scopus 로고    scopus 로고
    • Branch Migrating Sister Chromatid Junctions Form at Replication Origins through Rad51/Rad52-Independent Mechanisms
    • DOI 10.1016/S1097-2765(03)00473-8
    • Lopes M, Cotta-Ramusino C, Liberi G, Foiani M (2003) Branch migrating sister chromatid junctions form at replication origins through Rad51/Rad52-independent mechanisms. Mol Cell 12: 1499-1510 (Pubitemid 38037018)
    • (2003) Molecular Cell , vol.12 , Issue.6 , pp. 1499-1510
    • Lopes, M.1    Cotta-Ramusino, C.2    Liberi, G.3    Foiani, M.4
  • 27
    • 29544437558 scopus 로고    scopus 로고
    • Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
    • DOI 10.1016/j.molcel.2005.11.015, PII S1097276505018022
    • Lopes M, Foiani M, Sogo JM (2006b) Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions. Mol Cell 21: 15-27 (Pubitemid 43017845)
    • (2006) Molecular Cell , vol.21 , Issue.1 , pp. 15-27
    • Lopes, M.1    Foiani, M.2    Sogo, J.M.3
  • 28
    • 33845352895 scopus 로고    scopus 로고
    • Dynamic roles for G4 DNA in the biology of eukaryotic cells
    • DOI 10.1038/nsmb1171, PII NSMB1171
    • Maizels N (2006) Dynamic roles for G4 DNA in the biology of eukaryotic cells. Nat Struct Mol Biol 13: 1055-1059 (Pubitemid 44885914)
    • (2006) Nature Structural and Molecular Biology , vol.13 , Issue.12 , pp. 1055-1059
    • Maizels, N.1
  • 29
    • 1942518292 scopus 로고    scopus 로고
    • Anatomy and Dynamics of DNA Replication Fork Movement in Yeast Telomeric Regions
    • DOI 10.1128/MCB.24.9.4019-4031.2004
    • Makovets S, Herskowitz I, Blackburn EH (2004) Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions. Mol Cell Biol 24: 4019-4031 (Pubitemid 38496178)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.9 , pp. 4019-4031
    • Makovets, S.1    Herskowitz, I.2    Blackburn, E.H.3
  • 30
    • 12844289007 scopus 로고    scopus 로고
    • RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion
    • DOI 10.1128/MCB.25.3.933-944.2005
    • Malkova A, Naylor ML, Yamaguchi M, Ira G, Haber JE (2005) RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion. Mol Cell Biol 25: 933-944 (Pubitemid 40165802)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.3 , pp. 933-944
    • Malkova, A.1    Naylor, M.L.2    Yamaguchi, M.3    Ira, G.4    Haber, J.E.5
  • 35
    • 79957556530 scopus 로고    scopus 로고
    • DNA replication through G-Quadruplex motifs is promoted by the Saccharomyces cerevi-siae Pif1 DNA helicase
    • Paeschke K, Capra JK, Zakian VA (2011) DNA replication through G-Quadruplex motifs is promoted by the Saccharomyces cerevi-siae Pif1 DNA helicase. Cell 145: 678-691
    • (2011) Cell , vol.145 , pp. 678-691
    • Paeschke, K.1    Capra, J.K.2    Zakian, V.A.3
  • 36
    • 44849095213 scopus 로고    scopus 로고
    • Telomerase recruitment by the telomere end binding protein-β facilitates G-quadruplex DNA unfolding in ciliates
    • DOI 10.1038/nsmb.1422, PII NSMB1422
    • Paeschke K, Juranek S, Simonsson T, Hempel A, Rhodes D, Lipps HJ (2008) Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates. Nat Struct Mol Biol 15: 598-604 (Pubitemid 351799132)
    • (2008) Nature Structural and Molecular Biology , vol.15 , Issue.6 , pp. 598-604
    • Paeschke, K.1    Juranek, S.2    Simonsson, T.3    Hempel, A.4    Rhodes, D.5    Lipps, H.J.6
  • 37
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Pâques F, Haber JE (1999) Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 63: 349-404 (Pubitemid 29264976)
    • (1999) Microbiology and Molecular Biology Reviews , vol.63 , Issue.2 , pp. 349-404
    • Paques, F.1    Haber, J.E.2
  • 38
    • 0036345594 scopus 로고    scopus 로고
    • Yeast origins establish a strand bias for replicational mutagenesis
    • DOI 10.1016/S1097-2765(02)00567-1
    • Pavlov YI, Newlon CS, Kunkel TA (2002) Yeast origins establish a strand bias for replicational mutagenesis. Mol Cell 10 : 207-213 (Pubitemid 34876573)
    • (2002) Molecular Cell , vol.10 , Issue.1 , pp. 207-213
    • Pavlov, Y.I.1    Newlon, C.S.2    Kunkel, T.A.3
  • 40
    • 69949122831 scopus 로고    scopus 로고
    • Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway
    • Pike JE, Burgers PM, Campbell JL, Bambara RA (2009) Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway. J Biol Chem 284: 25170-25180
    • (2009) J Biol Chem , vol.284 , pp. 25170-25180
    • Pike, J.E.1    Burgers, P.M.2    Campbell, J.L.3    Bambara, R.A.4
  • 41
  • 45
    • 28944438876 scopus 로고    scopus 로고
    • Molecular evolution of minisatellites in hemiascomycetous yeasts
    • DOI 10.1093/molbev/msj022
    • Richard GF, Dujon B (2006) Molecular evolution of minisatellites in hemiascomycetous yeasts. Mol Biol Evol 23: 189-202. (Pubitemid 41785966)
    • (2006) Molecular Biology and Evolution , vol.23 , Issue.1 , pp. 189-202
    • Richard, G.-F.1    Dujon, B.2
  • 46
    • 54549127139 scopus 로고    scopus 로고
    • Comparative genomics and molecular dynamics of DNA repeats in eukaryotes
    • Richard GF, Kerrest A, Dujon B (2008) Comparative genomics and molecular dynamics of DNA repeats in eukaryotes. Microbiol Mol Biol Rev 72: 686-727
    • (2008) Microbiol Mol Biol Rev , vol.72 , pp. 686-727
    • Richard, G.F.1    Kerrest, A.2    Dujon, B.3
  • 47
    • 0030725454 scopus 로고    scopus 로고
    • Trinucleotide repeats affect DNA replication in vivo
    • DOI 10.1038/ng1197-298
    • Samadashwily GM, Raca G, Mirkin SM (1997) Trinucleotide repeats affect DNA replication in vivo. Nat Genet 17: 298-304 (Pubitemid 27475992)
    • (1997) Nature Genetics , vol.17 , Issue.3 , pp. 298-304
    • Samadashwily, G.M.1    Raca, G.2    Mirkin, S.M.3
  • 48
    • 77955487510 scopus 로고    scopus 로고
    • Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity
    • Sanders CM (2010) Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity. Biochem J 430: 119-128
    • (2010) Biochem J , vol.430 , pp. 119-128
    • Sanders, C.M.1
  • 49
    • 78649980436 scopus 로고    scopus 로고
    • Epigenetic instability due to defective replication of structured DNA
    • Sarkies P, Reams C, Simpson LJ, Sale JE (2010) Epigenetic instability due to defective replication of structured DNA. Mol Cell 40: 703-713
    • (2010) Mol Cell , vol.40 , pp. 703-713
    • Sarkies, P.1    Reams, C.2    Simpson, L.J.3    Sale, J.E.4
  • 50
    • 0028178792 scopus 로고
    • The Saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation
    • DOI 10.1016/0092-8674(94)90179-1
    • Schulz VP, Zakian VA (1994) The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation. Cell 76: 145-155 (Pubitemid 24035288)
    • (1994) Cell , vol.76 , Issue.1 , pp. 145-155
    • Schulz, V.P.1    Zakian, V.A.2
  • 54
    • 0033135161 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs
    • DOI 10.1093/nar/27.9.1978
    • Sun H, Bennett RJ, Maizels N (1999) The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs. Nucleic Acids Res 27: 1978-1984 (Pubitemid 29209557)
    • (1999) Nucleic Acids Research , vol.27 , Issue.9 , pp. 1978-1984
    • Sun, H.1    Bennett, R.J.2    Maizels, N.3
  • 56
    • 0033865403 scopus 로고    scopus 로고
    • Minisatellites: Mutability and genome architecture
    • DOI 10.1101/gr.10.7.899
    • Vergnaud G, Denoeud F (2000) Minisatellites: mutability and genome architecture. Genome Res 10 : 899-907 (Pubitemid 30608627)
    • (2000) Genome Research , vol.10 , Issue.7 , pp. 899-907
    • Vergnaud, G.1    Denoeud, F.2
  • 57
    • 0031004279 scopus 로고    scopus 로고
    • DNA secondary structures and the evolution of hypervariable tandem arrays
    • DOI 10.1074/jbc.272.14.9517
    • Weitzmann MN, Woodford KJ, Usdin K (1997) DNA secondary structures and the evolution of hypervariable tandem arrays. J Biol Chem 272: 9517-9523 (Pubitemid 27154969)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.14 , pp. 9517-9523
    • Weitzmann, M.N.1    Woodford, K.J.2    Usdin, K.3
  • 58
    • 77955791569 scopus 로고    scopus 로고
    • G-quadruplex nucleic acids and human disease
    • Wu Y, Brosh Jr RM (2010) G-quadruplex nucleic acids and human disease. FEBS J 277: 3470-3488
    • (2010) FEBS J , vol.277 , pp. 3470-3488
    • Wu, Y.1    Brosh Jr., R.M.2


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