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Volumn 35, Issue 16, 2007, Pages 5351-5359

A persistent RNA·DNA hybrid formed by transcription of the Friedreich ataxia triplet repeat in live bacteria, and by T7 RNAP in vitro

Author keywords

[No Author keywords available]

Indexed keywords

FRATAXIN; MESSENGER RNA; RNA POLYMERASE; BACTERIOPHAGE T7 RNA POLYMERASE; DNA; DNA DIRECTED RNA POLYMERASE; IRON BINDING PROTEIN; RNA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 34548775695     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm589     Document Type: Article
Times cited : (128)

References (54)
  • 1
    • 0015366533 scopus 로고
    • RNA-linked nascent DNA fragments in Escherichia coli
    • Sugino,A., Hirose,S. and Okazaki,R. (1972) RNA-linked nascent DNA fragments in Escherichia coli. Proc. Natl Acad. Sci. USA, 69 1863-1867.
    • (1972) Proc. Natl Acad. Sci. USA , vol.69 , pp. 1863-1867
    • Sugino, A.1    Hirose, S.2    Okazaki, R.3
  • 2
    • 4444379726 scopus 로고    scopus 로고
    • RNA displacement and resolution of the transcription bubble during transcription by T7 RNA polymerase
    • Jiang,M., Ma,N., Vassylyev,D.G. and McAllister,W.T. (2004) RNA displacement and resolution of the transcription bubble during transcription by T7 RNA polymerase. Mol. Cell, 15, 777-788.
    • (2004) Mol. Cell , vol.15 , pp. 777-788
    • Jiang, M.1    Ma, N.2    Vassylyev, D.G.3    McAllister, W.T.4
  • 3
    • 33745605508 scopus 로고    scopus 로고
    • Mapping the conformation of the nucleic acid framework of the T7 RNA polymerase elongation complex in solution using low-energy CD and fluorescence spectroscopy
    • Datta,K., Johnson,N.P. and von Hippel,P.H. (2006) Mapping the conformation of the nucleic acid framework of the T7 RNA polymerase elongation complex in solution using low-energy CD and fluorescence spectroscopy. J. Mol. Biol., 360, 800-813.
    • (2006) J. Mol. Biol , vol.360 , pp. 800-813
    • Datta, K.1    Johnson, N.P.2    von Hippel, P.H.3
  • 4
    • 33746827367 scopus 로고    scopus 로고
    • The role of the largest RNA polymerase subunit lid element in preventing the formation of extended RNA-DNA hybrid
    • Naryshkina,T., Kuznedelov,K. and Severinov,K. (2006) The role of the largest RNA polymerase subunit lid element in preventing the formation of extended RNA-DNA hybrid. J. Mol. Biol., 361, 634-643.
    • (2006) J. Mol. Biol , vol.361 , pp. 634-643
    • Naryshkina, T.1    Kuznedelov, K.2    Severinov, K.3
  • 5
    • 33746811857 scopus 로고    scopus 로고
    • The role of the lid element in transcription by E. coli RNA polymerase
    • Toulokhonov,I. and Landick, R. (2006) The role of the lid element in transcription by E. coli RNA polymerase. J. Mol. Biol., 361, 644-658.
    • (2006) J. Mol. Biol , vol.361 , pp. 644-658
    • Toulokhonov, I.1    Landick, R.2
  • 6
    • 0025084228 scopus 로고
    • Ribonuclease H: From discovery to 3D structure
    • Crouch,R.J. (1990) Ribonuclease H: From discovery to 3D structure. New Biol., 2, 771-777.
    • (1990) New Biol , vol.2 , pp. 771-777
    • Crouch, R.J.1
  • 7
    • 0030014783 scopus 로고    scopus 로고
    • DNA Topoisomerases
    • Wang,J.C. (1996) DNA Topoisomerases; Annu. Rev. Biochem., 65 635-692.
    • (1996) Annu. Rev. Biochem , vol.65 , pp. 635-692
    • Wang, J.C.1
  • 8
    • 0023433855 scopus 로고
    • Supercoiling of the DNA template during transcription
    • Liu,L.F. and Wang,J.C. (1987) Supercoiling of the DNA template during transcription. Proc. Natl Acad. Sci. USA, 84, 7024-7027.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 7024-7027
    • Liu, L.F.1    Wang, J.C.2
  • 9
    • 0024299511 scopus 로고    scopus 로고
    • Transcription-dependent DNA supercoiling in yeast DNA topoisomerase mutants
    • Brill,S.J. and Sternglanz,R. (1998) Transcription-dependent DNA supercoiling in yeast DNA topoisomerase mutants. Cell, 54, 403-411.
    • (1998) Cell , vol.54 , pp. 403-411
    • Brill, S.J.1    Sternglanz, R.2
  • 10
    • 0029558248 scopus 로고
    • Transcribing of Escherichia coli genes with mutant T7 RNA polymerases: Stability of lacZ mRNA inversely correlates with polymerase speed
    • Makarova,O.V., Makarov,E.M., Sousa,R. and Dreyfus,M. (1995) Transcribing of Escherichia coli genes with mutant T7 RNA polymerases: Stability of lacZ mRNA inversely correlates with polymerase speed. Proc. Natl Acad. Sci. USA, 92, 12250-12254.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 12250-12254
    • Makarova, O.V.1    Makarov, E.M.2    Sousa, R.3    Dreyfus, M.4
  • 11
    • 0033522905 scopus 로고    scopus 로고
    • Escherichia coli DNA topoisomerase I inhibits R-loop formation by relaxing transcription-induced negative supercoiling
    • Masse,E. and Drolet,M. (1999) Escherichia coli DNA topoisomerase I inhibits R-loop formation by relaxing transcription-induced negative supercoiling. J. Biol. Chem., 274, 16659-16664.
    • (1999) J. Biol. Chem , vol.274 , pp. 16659-16664
    • Masse, E.1    Drolet, M.2
  • 13
    • 3343003673 scopus 로고    scopus 로고
    • Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes
    • Abruzzi,K.C., Lacadie,S. and Rosbash,M. (2004) Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes. EMBO J., 23, 2620-2631.
    • (2004) EMBO J , vol.23 , pp. 2620-2631
    • Abruzzi, K.C.1    Lacadie, S.2    Rosbash, M.3
  • 14
    • 1242319345 scopus 로고    scopus 로고
    • Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex
    • Hurt,E., Luo,M.J., Rother,S., Reed,R. and Strasser,K. (2004) Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex. Proc. Natl Acad. Sci. USA, 101, 1858-1862.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 1858-1862
    • Hurt, E.1    Luo, M.J.2    Rother, S.3    Reed, R.4    Strasser, K.5
  • 15
    • 22344438756 scopus 로고    scopus 로고
    • Recruitment of the human TREX complex to mRNA during splicing
    • Masuda,S., Das,R., Cheng,H., Hurt,E., Dorman,N. and Reed,R. (2005) Recruitment of the human TREX complex to mRNA during splicing. Genes Dev., 19, 1512-1517.
    • (2005) Genes Dev , vol.19 , pp. 1512-1517
    • Masuda, S.1    Das, R.2    Cheng, H.3    Hurt, E.4    Dorman, N.5    Reed, R.6
  • 16
    • 0141643143 scopus 로고    scopus 로고
    • Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation
    • Rondon,A.G., Jimeno,S., Garcia-Rubio,M. and Aguilera,A. (2003) Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation. J. Biol. Chem., 278, 39037-39043.
    • (2003) J. Biol. Chem , vol.278 , pp. 39037-39043
    • Rondon, A.G.1    Jimeno, S.2    Garcia-Rubio, M.3    Aguilera, A.4
  • 17
    • 0141819093 scopus 로고    scopus 로고
    • Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination
    • Huertas,P. and Aguilera,A. (2003) Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol. Cell, 12, 711-721.
    • (2003) Mol. Cell , vol.12 , pp. 711-721
    • Huertas, P.1    Aguilera, A.2
  • 18
    • 20444366920 scopus 로고    scopus 로고
    • Interdependence between transcription and mRNP processing and export, and its impact on genetic stability
    • Luna,R., Jimeno,S., Marin,M., Huertas,P., Garcia-Rubio,M. and Aguilera,A. (2005) Interdependence between transcription and mRNP processing and export, and its impact on genetic stability. Mol. Cell 18, 711-722.
    • (2005) Mol. Cell , vol.18 , pp. 711-722
    • Luna, R.1    Jimeno, S.2    Marin, M.3    Huertas, P.4    Garcia-Rubio, M.5    Aguilera, A.6
  • 19
    • 23744455164 scopus 로고    scopus 로고
    • Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability
    • Li,X. and Manley,J.L. (2005) Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability. Cell, 122, 365-378.
    • (2005) Cell , vol.122 , pp. 365-378
    • Li, X.1    Manley, J.L.2
  • 20
    • 0025225502 scopus 로고
    • Induction of RNA-stabilized DNA conformers by transcription of an immunoglobulin switch region
    • Reaban,M.E. and Griffin,J.A. (1990) Induction of RNA-stabilized DNA conformers by transcription of an immunoglobulin switch region. Nature, 348, 342-344.
    • (1990) Nature , vol.348 , pp. 342-344
    • Reaban, M.E.1    Griffin, J.A.2
  • 21
    • 0029598833 scopus 로고
    • RNA:DNA complex formation upon transcription of immunoglobulin switch regions: Implications for the mechanism and regulation of class switch recombination
    • Daniels,G.A. and Lieber,M.R. (1995) RNA:DNA complex formation upon transcription of immunoglobulin switch regions: Implications for the mechanism and regulation of class switch recombination. Nucleic Acids Res., 23, 5006-5011.
    • (1995) Nucleic Acids Res , vol.23 , pp. 5006-5011
    • Daniels, G.A.1    Lieber, M.R.2
  • 25
    • 0031941447 scopus 로고    scopus 로고
    • The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure
    • Bidichandani,S.I., Ashizawa,T. and Patel,P.I. (1998) The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure. Am. J. Hum. Genet., 62, 111-121.
    • (1998) Am. J. Hum. Genet , vol.62 , pp. 111-121
    • Bidichandani, S.I.1    Ashizawa, T.2    Patel, P.I.3
  • 26
    • 0032486276 scopus 로고    scopus 로고
    • Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo
    • Ohshima,K., Montermini,L., Wells,R.D. and Pandolfo,M. (1998) Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo. J. Biol. Chem., 273, 14588-14595.
    • (1998) J. Biol. Chem , vol.273 , pp. 14588-14595
    • Ohshima, K.1    Montermini, L.2    Wells, R.D.3    Pandolfo, M.4
  • 27
    • 0033120042 scopus 로고    scopus 로고
    • Sticky DNA: Self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia
    • Sakamoto,N., Chastain,P.D., Parniewski,P., Ohshima,K., Pandolfo,M., Griffith,J.D. and Wells,R.D. (1999) Sticky DNA: Self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia. Mol. Cell, 3, 465-475.
    • (1999) Mol. Cell , vol.3 , pp. 465-475
    • Sakamoto, N.1    Chastain, P.D.2    Parniewski, P.3    Ohshima, K.4    Pandolfo, M.5    Griffith, J.D.6    Wells, R.D.7
  • 28
    • 0034660695 scopus 로고    scopus 로고
    • The GAA TTC triplet repeat expanded in Friedreich's ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner
    • Grabczyk,E. and Usdin,K. (2000) The GAA TTC triplet repeat expanded in Friedreich's ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner. Nucleic Acids Res., 28, 2815-2822.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2815-2822
    • Grabczyk, E.1    Usdin, K.2
  • 29
    • 0037464584 scopus 로고    scopus 로고
    • DNA triplet repeats mediate heterochromatin-protein-1-sensitive variegated gene silencing
    • Saveliev,A., Everett,C., Sharpe,T., Webster,Z. and Festenstein,R. (2003) DNA triplet repeats mediate heterochromatin-protein-1-sensitive variegated gene silencing. Nature, 422, 909-913.
    • (2003) Nature , vol.422 , pp. 909-913
    • Saveliev, A.1    Everett, C.2    Sharpe, T.3    Webster, Z.4    Festenstein, R.5
  • 31
    • 0034672110 scopus 로고    scopus 로고
    • Alleviating transcript insufficiency caused by Friedreich's ataxia triplet repeats
    • Grabczyk,E. and Usdin,K. (2000) Alleviating transcript insufficiency caused by Friedreich's ataxia triplet repeats. Nucleic Acids Res,, 28, 4930-4937.
    • (2000) Nucleic Acids Res , vol.28 , pp. 4930-4937
    • Grabczyk, E.1    Usdin, K.2
  • 32
    • 0033080760 scopus 로고    scopus 로고
    • Generation of microgram quantities of trinucleotide repeat tracts of defined length, interspersion pattern, and orientation
    • Grabczyk,E. and Usdin,K. (1999) Generation of microgram quantities of trinucleotide repeat tracts of defined length, interspersion pattern, and orientation. Anal. Biochem., 267, 241-243.
    • (1999) Anal. Biochem , vol.267 , pp. 241-243
    • Grabczyk, E.1    Usdin, K.2
  • 33
    • 0029018327 scopus 로고
    • Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter
    • Guzman,L.M., Belin,D., Carson,M.J. and Beckwith,J. (1995) Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. J. Bacteriol., 177, 4121-4130.
    • (1995) J. Bacteriol , vol.177 , pp. 4121-4130
    • Guzman, L.M.1    Belin, D.2    Carson, M.J.3    Beckwith, J.4
  • 34
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski,P. and Sacchi,N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
    • (1987) Anal. Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 35
    • 0033607485 scopus 로고    scopus 로고
    • R-loop-dependent hypernegative supercoiling in Escherichia coli topA mutants preferentially occurs at low temperatures and correlates with growth inhibition
    • Masse,E. and Drolet,M. (1999) R-loop-dependent hypernegative supercoiling in Escherichia coli topA mutants preferentially occurs at low temperatures and correlates with growth inhibition. J. Mol. Biol. 294, 321-332.
    • (1999) J. Mol. Biol , vol.294 , pp. 321-332
    • Masse, E.1    Drolet, M.2
  • 36
    • 0034595503 scopus 로고    scopus 로고
    • Overextended RNA:DNA hybrid as a negative regulator of RNA polymerase II processivity
    • Kireeva,M.L., Komissarova,N. and Kashlev,M. (2000) Overextended RNA:DNA hybrid as a negative regulator of RNA polymerase II processivity. J. Mol. Biol., 299, 325-335.
    • (2000) J. Mol. Biol , vol.299 , pp. 325-335
    • Kireeva, M.L.1    Komissarova, N.2    Kashlev, M.3
  • 37
    • 0027190015 scopus 로고
    • DNA sequences at immunoglobulin switch region recombination sites
    • Dunnick,W., Hertz,G.Z., Scappino,L. and Gritzmacher,C. (1993) DNA sequences at immunoglobulin switch region recombination sites. Nucleic Acids Res., 21, 365-372.
    • (1993) Nucleic Acids Res , vol.21 , pp. 365-372
    • Dunnick, W.1    Hertz, G.Z.2    Scappino, L.3    Gritzmacher, C.4
  • 38
    • 0037650190 scopus 로고    scopus 로고
    • R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
    • Yu,K., Chedin,F., Hsieh,C.L., Wilson,T.E. and Lieber,M.R. (2003) R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nat. Immunol., 4, 442-451.
    • (2003) Nat. Immunol , vol.4 , pp. 442-451
    • Yu, K.1    Chedin, F.2    Hsieh, C.L.3    Wilson, T.E.4    Lieber, M.R.5
  • 39
    • 33645527783 scopus 로고    scopus 로고
    • Huang,F.T., Yu,K., Hsieh.C.L. and Lieber,M.R. (2006) Downstream boundary of chromosomal R-loops at murine switch regions: Implications for the mechanism of class switch recombination. Proc. Natl Acad. Sci. USA 103, 5030-5035.
    • Huang,F.T., Yu,K., Hsieh.C.L. and Lieber,M.R. (2006) Downstream boundary of chromosomal R-loops at murine switch regions: Implications for the mechanism of class switch recombination. Proc. Natl Acad. Sci. USA 103, 5030-5035.
  • 41
    • 0028929024 scopus 로고
    • A long purine-pyrimidine homopolymer acts as a transcriptional diode
    • Grabczyk,E. and Fishman,M.C. (1995) A long purine-pyrimidine homopolymer acts as a transcriptional diode. J. Biol. Chem., 270, 1791-1797.
    • (1995) J. Biol. Chem , vol.270 , pp. 1791-1797
    • Grabczyk, E.1    Fishman, M.C.2
  • 42
    • 3042785608 scopus 로고    scopus 로고
    • Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA
    • Duquette,M.L., Handa,P., Vincent,J.A., Taylor,A.F. and Maizels,N. (2004) Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA. Genes Dev., 18, 1618-1629.
    • (2004) Genes Dev , vol.18 , pp. 1618-1629
    • Duquette, M.L.1    Handa, P.2    Vincent, J.A.3    Taylor, A.F.4    Maizels, N.5
  • 43
    • 0029883306 scopus 로고    scopus 로고
    • Stability of intrastrand hairpin structures formed by the CAG/CTG class of DNA triplet repeats associated with neurological diseases
    • Petruska,J., Arnheim,N. and Goodman,M.F. (1996) Stability of intrastrand hairpin structures formed by the CAG/CTG class of DNA triplet repeats associated with neurological diseases. Nucleic Acids Res., 24 1992-1998.
    • (1996) Nucleic Acids Res , vol.24 , pp. 1992-1998
    • Petruska, J.1    Arnheim, N.2    Goodman, M.F.3
  • 44
    • 0028318228 scopus 로고
    • Sequence specific thermodynamic and structural properties for DNA.RNA duplexes
    • Ratmeyer,L., Vinayak,R., Zhong,Y.Y., Zon,G. and Wilson,W.D. (1994) Sequence specific thermodynamic and structural properties for DNA.RNA duplexes. Biochemistry, 33, 5298-5304.
    • (1994) Biochemistry , vol.33 , pp. 5298-5304
    • Ratmeyer, L.1    Vinayak, R.2    Zhong, Y.Y.3    Zon, G.4    Wilson, W.D.5
  • 45
    • 0028904989 scopus 로고
    • Origins of the large differences in stability of DNA and RNA helices: C-5 methyl and 2′-hydroxyl effects
    • Wang,S. and Kool,E.T. (1995) Origins of the large differences in stability of DNA and RNA helices: C-5 methyl and 2′-hydroxyl effects. Biochemistry, 34, 4125-4132.
    • (1995) Biochemistry , vol.34 , pp. 4125-4132
    • Wang, S.1    Kool, E.T.2
  • 46
    • 0029121625 scopus 로고
    • Relative thermodynamic stability of DNA, RNA, and RNA:RNA hybrid duplexes: Relationship with base composition and structure
    • Lesnik,E.A. and Freier,S.M. (1995) Relative thermodynamic stability of DNA, RNA, and RNA:RNA hybrid duplexes: relationship with base composition and structure. Biochemistry, 34, 10807-10815.
    • (1995) Biochemistry , vol.34 , pp. 10807-10815
    • Lesnik, E.A.1    Freier, S.M.2
  • 47
    • 0024598556 scopus 로고
    • Intramolecular DNA triplexes in supercoiled plasmids. I. Effect of loop size on formation and stability
    • Shimizu,M., Hanvey,J.C. and Wells,R.D. (1989) Intramolecular DNA triplexes in supercoiled plasmids. I. Effect of loop size on formation and stability. J. Biol. Chem., 264, 5944-5949.
    • (1989) J. Biol. Chem , vol.264 , pp. 5944-5949
    • Shimizu, M.1    Hanvey, J.C.2    Wells, R.D.3
  • 48
    • 0032012128 scopus 로고    scopus 로고
    • GAA instability in Friedreich's Ataxia shares a common, DNA-directed and intraallelic mechanism with other trinucleotide diseases
    • Gacy,A.M., Goellner,G.M., Spiro,C., Chen,X., Gupta,G., Bradbury,E.M., Dyer,R.B., Mikesell,M.J., Yao,J.Z. et al. (1998) GAA instability in Friedreich's Ataxia shares a common, DNA-directed and intraallelic mechanism with other trinucleotide diseases. Mol. Cell, 1, 583-593.
    • (1998) Mol. Cell , vol.1 , pp. 583-593
    • Gacy, A.M.1    Goellner, G.M.2    Spiro, C.3    Chen, X.4    Gupta, G.5    Bradbury, E.M.6    Dyer, R.B.7    Mikesell, M.J.8    Yao, J.Z.9
  • 49
    • 0035503680 scopus 로고    scopus 로고
    • Fragile X syndrome and Friedreich's ataxia: Two different paradigms for repeat induced transcript insufficiency
    • Grabczyk,E., Kumari,D. and Usdin,K. (2001) Fragile X syndrome and Friedreich's ataxia: Two different paradigms for repeat induced transcript insufficiency. Brain Res. Bull., 56, 367-373.
    • (2001) Brain Res. Bull , vol.56 , pp. 367-373
    • Grabczyk, E.1    Kumari, D.2    Usdin, K.3
  • 51
    • 0031739916 scopus 로고    scopus 로고
    • Parental gender, age at birth and expansion length influence GAA repeat intergenerational instability in the X25 gene: Pedigree studies and analysis of sperm from patients with Friedreich's ataxia
    • De Michele,G., Cavalcanti,F., Criscuolo,C., Pianese,L., Monticelli,A., Filla,A. and Cocozza,S. (1998) Parental gender, age at birth and expansion length influence GAA repeat intergenerational instability in the X25 gene: Pedigree studies and analysis of sperm from patients with Friedreich's ataxia. Hum. Mol. Genet., 7, 1901-1906.
    • (1998) Hum. Mol. Genet , vol.7 , pp. 1901-1906
    • De Michele, G.1    Cavalcanti, F.2    Criscuolo, C.3    Pianese, L.4    Monticelli, A.5    Filla, A.6    Cocozza, S.7
  • 52
    • 0030815628 scopus 로고    scopus 로고
    • Somatic mosaicism for Friedreich's ataxia GAA triplet repeat expansions in the central nervous system
    • Montermini,L., Kish,S.J., Jiralerspong,S., Lamarche, J.B. and Pandolfo,M. (1997) Somatic mosaicism for Friedreich's ataxia GAA triplet repeat expansions in the central nervous system. Neurology, 49 606-610.
    • (1997) Neurology , vol.49 , pp. 606-610
    • Montermini, L.1    Kish, S.J.2    Jiralerspong, S.3    Lamarche, J.B.4    Pandolfo, M.5
  • 53
    • 0035065524 scopus 로고    scopus 로고
    • Trinucleotide expansion in haploid germ cells by gap repair
    • Kovtun,I.V. and McMurray,C.T. (2001) Trinucleotide expansion in haploid germ cells by gap repair. Nat. Genet., 27, 407-411.
    • (2001) Nat. Genet , vol.27 , pp. 407-411
    • Kovtun, I.V.1    McMurray, C.T.2
  • 54
    • 0037081784 scopus 로고    scopus 로고
    • Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins
    • van den Broek,W.J., Nelen,M.R., Wansink,D.G., Coerwinkel,M.M., te Riele,H., Groenen,P.J. and Wieringa,B. (2002) Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins. Hum. Mol. Genet., 11, 191-198.
    • (2002) Hum. Mol. Genet , vol.11 , pp. 191-198
    • van den Broek, W.J.1    Nelen, M.R.2    Wansink, D.G.3    Coerwinkel, M.M.4    te Riele, H.5    Groenen, P.J.6    Wieringa, B.7


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