Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability

Genes and Development

Volumn 19, Issue 22, 2005, Pages 2715-2726

  Schwartz, Michal ^a   Zlotorynski, Eitan ^b   Goldberg, Michal ^a   Ozeri, Efrat ^a   Rahat, Ayelet ^a   Le Sage, Carlos ^b   Chen, Benjamin P C ^c   Chen, David J ^c   Agami, Reuven ^b   Kerem, Batsheva ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Common fragile sites; Double strand breaks; Genomic instability; Homologous recombination; Nonhomologous end joining; Replication stress

Indexed keywords

DNA; DOUBLE STRANDED DNA; HISTONE H2A; LIGASE; LIGASE IV; MEDIATOR OF DNA DAMAGE CHECKPOINT PROTEIN 1; MOLECULAR MARKER; PHOSPHOPROTEIN; PROTEIN KINASE; RAD51 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOMAL INSTABILITY; CHROMOSOME FRAGILE SITE; CHROMOSOME REPLICATION; DNA REPAIR; DNA STRAND BREAKAGE; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE LOCATION; GENETIC MARKER; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; METAPHASE CHROMOSOME; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

CELL LINE, TUMOR; CHROMOSOME FRAGILE SITES; DNA LIGASES; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; HELA CELLS; HISTONES; HUMANS; METAPHASE; NUCLEAR PROTEINS; PHOSPHORYLATION; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 27744496209     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.340905     Document Type: Article

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