메뉴 건너뛰기




Volumn 238, Issue 9, 2013, Pages 971-990

Non-Hodgkin's B-cell lymphoma: Advances in molecular strategies targeting drug resistance

Author keywords

Akt; apoptosis; B cell lymphoma; cluster differentiation antigens; drug metabolism; Drug resistance; epigenetics; geranylation; MAP kinases; mechanisms of drug resistance; microRNAs; microsatellite instability; multidrug resistance; NF B; NHL; oxidative stress; p53; positive regulatory domain I protein; proteasome; retinaldehyde dehydrogenase; sphingosine kinase; stroma; stromal influences; TGF ; tyrosine kinases; zinc transporter

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; BCL2 RELATED PROTEIN A1; BORTEZOMIB; CD147 ANTIGEN; CD20 ANTIGEN; GALLIUM NITRATE; GLUTATHIONE TRANSFERASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HISTONE DEACETYLASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA 21; MITOGEN ACTIVATED PROTEIN KINASE; MULTIDRUG RESISTANCE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; PROTEIN TYROSINE KINASE; PROTON PUMP; REACTIVE OXYGEN METABOLITE; RETINAL DEHYDROGENASE; RITUXIMAB; SPHINGOSINE KINASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNINDEXED DRUG; VORINOSTAT; X LINKED INHIBITOR OF APOPTOSIS;

EID: 84884251741     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370213498985     Document Type: Article
Times cited : (43)

References (398)
  • 1
    • 0031927984 scopus 로고    scopus 로고
    • New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin's Lymphoma Classification Project
    • Armitage JO,Weisenburger DD.New approach to classifying non-Hodgkin's lymphomas: clinical features of the major histologic subtypes. Non-Hodgkin's Lymphoma Classification Project.J Clin Oncol. 1998;16:2780-95.
    • (1998) J Clin Oncol , vol.16 , pp. 2780-2795
    • Armitage, J.O.1    Weisenburger, D.D.2
  • 2
    • 33645898348 scopus 로고    scopus 로고
    • Monoclonal antibody as therapy for malignant lymphomas
    • Coiffier B.Monoclonal antibody as therapy for malignant lymphomas.CR Biol. 2006;329:241-54.
    • (2006) CR Biol , vol.329 , pp. 241-254
    • Coiffier, B.1
  • 3
    • 37549015263 scopus 로고    scopus 로고
    • Germinal centres: role in B-cell physiology and malignancy
    • Klein U,Dalla-Favera R.Germinal centres: role in B-cell physiology and malignancy.Nat Rev Immunol. 2008;8:22-33.
    • (2008) Nat Rev Immunol , vol.8 , pp. 22-33
    • Klein, U.1    Dalla-Favera, R.2
  • 4
    • 0025122529 scopus 로고
    • CHOP chemotherapy as standard therapy for treatment of patients with diffuse histiocytic lymphoma
    • Fisher RI.CHOP chemotherapy as standard therapy for treatment of patients with diffuse histiocytic lymphoma.Important Adv Oncol. 1990;:217-25.
    • (1990) Important Adv Oncol , pp. 217-225
    • Fisher, R.I.1
  • 5
    • 77956108221 scopus 로고    scopus 로고
    • Recent advances in the treatment of mantle cell lymphoma: a post-ASH 2009 discussion
    • Czuczman MS,Leonard JP,Williams ME.Recent advances in the treatment of mantle cell lymphoma: a post-ASH 2009 discussion.Clin Adv Hematol Oncol. 2010;8:A1-14; quiz A15.
    • (2010) Clin Adv Hematol Oncol , vol.8
    • Czuczman, M.S.1    Leonard, J.P.2    Williams, M.E.3
  • 7
    • 0025761928 scopus 로고
    • Prognostic factors in aggressive lymphoma
    • Velasquez WS.Prognostic factors in aggressive lymphoma.J Clin Oncol. 1991;9:1320-1.
    • (1991) J Clin Oncol , vol.9 , pp. 1320-1321
    • Velasquez, W.S.1
  • 8
    • 0027487419 scopus 로고
    • Prognostic factors in intermediate high grade lymphoma
    • Velasquez WS.Prognostic factors in intermediate high grade lymphoma.Cancer Treat Res. 1993;66:37-52.
    • (1993) Cancer Treat Res , vol.66 , pp. 37-52
    • Velasquez, W.S.1
  • 11
  • 13
    • 0038805260 scopus 로고    scopus 로고
    • Epidemiology of Hodgkin's disease and non-Hodgkin's lymphoma
    • Swerdlow AJ.Epidemiology of Hodgkin's disease and non-Hodgkin's lymphoma.Eur J Nucl Med Mol Imaging. 2003;30:S3-12.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 3-12
    • Swerdlow, A.J.1
  • 17
    • 0035352412 scopus 로고    scopus 로고
    • New therapies, new directions: advances in the systemic treatment of metastatic colorectal cancer
    • Holen KD,Saltz LB.New therapies, new directions: advances in the systemic treatment of metastatic colorectal cancer.Lancet Oncol. 2001;2:290-7.
    • (2001) Lancet Oncol , vol.2 , pp. 290-297
    • Holen, K.D.1    Saltz, L.B.2
  • 18
    • 23244462775 scopus 로고    scopus 로고
    • Non-Hodgkin lymphoma: diagnosis and treatment
    • Ansell SM,Armitage J.Non-Hodgkin lymphoma: diagnosis and treatment.Mayo Clin Proc. 2005;80:1087-97.
    • (2005) Mayo Clin Proc , vol.80 , pp. 1087-1097
    • Ansell, S.M.1    Armitage, J.2
  • 19
    • 59249103604 scopus 로고    scopus 로고
    • Novel therapies in peripheral T-cell lymphomas
    • O'Leary HM,Savage KJ.Novel therapies in peripheral T-cell lymphomas.Curr Hematol Malig Rep. 2008;3:213-20.
    • (2008) Curr Hematol Malig Rep , vol.3 , pp. 213-220
    • O'Leary, H.M.1    Savage, K.J.2
  • 20
    • 33847366355 scopus 로고    scopus 로고
    • Rituximab in lymphoma: a systematic review and consensus practice guideline from Cancer Care Ontario
    • Cheung MC,Haynes AE,Meyer RM,Stevens A,Imrie KR.Rituximab in lymphoma: a systematic review and consensus practice guideline from Cancer Care Ontario.Cancer Treat Rev. 2007;33:161-76.
    • (2007) Cancer Treat Rev , vol.33 , pp. 161-176
    • Cheung, M.C.1    Haynes, A.E.2    Meyer, R.M.3    Stevens, A.4    Imrie, K.R.5
  • 21
    • 34250743767 scopus 로고    scopus 로고
    • Diffuse large B-cell lymphoma
    • Ng AK.Diffuse large B-cell lymphoma.Semin Radiat Oncol. 2007;17:169-75.
    • (2007) Semin Radiat Oncol , vol.17 , pp. 169-175
    • Ng, A.K.1
  • 23
    • 0027376013 scopus 로고
    • Natural history of and therapy for the indolent non-Hodgkin's lymphomas
    • Horning SJ.Natural history of and therapy for the indolent non-Hodgkin's lymphomas.Semin Oncol. 1993;20:75-88.
    • (1993) Semin Oncol , vol.20 , pp. 75-88
    • Horning, S.J.1
  • 24
    • 0030960280 scopus 로고    scopus 로고
    • Mantle cell lymphoma: diagnostic criteria, clinical aspects and therapeutic problems
    • Meusers P,Hense J,Brittinger G.Mantle cell lymphoma: diagnostic criteria, clinical aspects and therapeutic problems.Leukemia. 1997;11:S60-4.
    • (1997) Leukemia , vol.11
    • Meusers, P.1    Hense, J.2    Brittinger, G.3
  • 25
    • 54049129362 scopus 로고    scopus 로고
    • Therapy of mantle cell lymphoma: current standards and future strategies
    • ix
    • Schmidt C,Dreyling M.Therapy of mantle cell lymphoma: current standards and future strategies.Hematol Oncol Clin North Am. 22:953-63, ix.
    • Hematol Oncol Clin North Am , vol.22 , pp. 953-963
    • Schmidt, C.1    Dreyling, M.2
  • 31
    • 0031839821 scopus 로고    scopus 로고
    • MDR1 and MRP expression in chronic B-cell lymphoproliferative disorders
    • Webb M,Brun M,McNiven M,Le Couteur D,Craft P.MDR1 and MRP expression in chronic B-cell lymphoproliferative disorders.Br J Haematol. 1998;102:710-7.
    • (1998) Br J Haematol , vol.102 , pp. 710-717
    • Webb, M.1    Brun, M.2    McNiven, M.3    Le Couteur, D.4    Craft, P.5
  • 32
    • 57049175821 scopus 로고    scopus 로고
    • Pathway activation in large B-cell non-Hodgkin lymphoma cell lines by doxorubicin reveals prognostic markers of in vivo response
    • Houldsworth J,Petlakh M,Olshen AB,Chaganti RS.Pathway activation in large B-cell non-Hodgkin lymphoma cell lines by doxorubicin reveals prognostic markers of in vivo response.Leuk Lymphoma. 2008;49:2170-80.
    • (2008) Leuk Lymphoma , vol.49 , pp. 2170-2180
    • Houldsworth, J.1    Petlakh, M.2    Olshen, A.B.3    Chaganti, R.S.4
  • 35
    • 0043192901 scopus 로고    scopus 로고
    • A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma
    • Wright G,Tan B,Rosenwald A,Hurt EH,Wiestner A,Staudt LM.A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma.Proc Natl Acad Sci USA. 2003;100:9991-6.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9991-9996
    • Wright, G.1    Tan, B.2    Rosenwald, A.3    Hurt, E.H.4    Wiestner, A.5    Staudt, L.M.6
  • 37
    • 0035905313 scopus 로고    scopus 로고
    • Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells
    • Davis RE,Brown KD,Siebenlist U,Staudt LM.Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells.J Exp Med. 2001;194:1861-74.
    • (2001) J Exp Med , vol.194 , pp. 1861-1874
    • Davis, R.E.1    Brown, K.D.2    Siebenlist, U.3    Staudt, L.M.4
  • 40
    • 0031459455 scopus 로고    scopus 로고
    • The clinical outcome of 65 cases of mantle cell lymphoma initially treated with non-intensive therapy by the British National Lymphoma Investigation Group
    • Vandenberghe E,De Wolf-Peeters C,Vaughan Hudson G,Hudson BV,Pittaluga S,Anderson L,Linch DC.The clinical outcome of 65 cases of mantle cell lymphoma initially treated with non-intensive therapy by the British National Lymphoma Investigation Group.Br J Haematol. 1997;99:842-7.
    • (1997) Br J Haematol , vol.99 , pp. 842-847
    • Vandenberghe, E.1    de Wolf-Peeters, C.2    Vaughan Hudson, G.3    Hudson, B.V.4    Pittaluga, S.5    Anderson, L.6    Linch, D.C.7
  • 42
    • 34648824397 scopus 로고    scopus 로고
    • Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics
    • Jares P,Colomer D,Campo E.Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics.Nat Rev Cancer. 2007;7:750-62.
    • (2007) Nat Rev Cancer , vol.7 , pp. 750-762
    • Jares, P.1    Colomer, D.2    Campo, E.3
  • 43
    • 47149105457 scopus 로고    scopus 로고
    • Mantle cell lymphoma: advances in biology and therapy
    • Smith MR.Mantle cell lymphoma: advances in biology and therapy.Curr Opin Hematol. 2008;15:415-21.
    • (2008) Curr Opin Hematol , vol.15 , pp. 415-421
    • Smith, M.R.1
  • 45
    • 33744486857 scopus 로고    scopus 로고
    • Constitutive NF-kappaB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas
    • Fu L,Lin-Lee YC,Pham LV,Tamayo A,Yoshimura L,Ford RJ.Constitutive NF-kappaB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas.Blood. 2006;107:4540-8.
    • (2006) Blood , vol.107 , pp. 4540-4548
    • Fu, L.1    Lin-Lee, Y.C.2    Pham, L.V.3    Tamayo, A.4    Yoshimura, L.5    Ford, R.J.6
  • 46
    • 0038206722 scopus 로고    scopus 로고
    • Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis
    • Pham LV,Tamayo AT,Yoshimura LC,Lo P,Ford RJ.Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis.J Immunol. 2003;171:88-95.
    • (2003) J Immunol , vol.171 , pp. 88-95
    • Pham, L.V.1    Tamayo, A.T.2    Yoshimura, L.C.3    Lo, P.4    Ford, R.J.5
  • 47
    • 23044479821 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma
    • Shishodia S,Amin HM,Lai R,Aggarwal BB.Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma.Biochem Pharmacol. 2005;70:700-13.
    • (2005) Biochem Pharmacol , vol.70 , pp. 700-713
    • Shishodia, S.1    Amin, H.M.2    Lai, R.3    Aggarwal, B.B.4
  • 51
    • 24944592507 scopus 로고    scopus 로고
    • Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways
    • Rizzatti EG,Falcao RP,Panepucci RA,Proto-Siqueira R,Anselmo-Lima WT,Okamoto OK,Zago MA.Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways.Br J Haematol. 2005;130:516-26.
    • (2005) Br J Haematol , vol.130 , pp. 516-526
    • Rizzatti, E.G.1    Falcao, R.P.2    Panepucci, R.A.3    Proto-Siqueira, R.4    Anselmo-Lima, W.T.5    Okamoto, O.K.6    Zago, M.A.7
  • 52
    • 42049110004 scopus 로고    scopus 로고
    • Noxa mediates bortezomib induced apoptosis in both sensitive and intrinsically resistant mantle cell lymphoma cells and this effect is independent of constitutive activity of the AKT and NF-kappaB pathways
    • Rizzatti EG,Mora-Jensen H,Weniger MA,Gibellini F,Lee E,Daibata M,Lai R,Wiestner A.Noxa mediates bortezomib induced apoptosis in both sensitive and intrinsically resistant mantle cell lymphoma cells and this effect is independent of constitutive activity of the AKT and NF-kappaB pathways.Leuk Lymphoma. 2008;49:798-808.
    • (2008) Leuk Lymphoma , vol.49 , pp. 798-808
    • Rizzatti, E.G.1    Mora-Jensen, H.2    Weniger, M.A.3    Gibellini, F.4    Lee, E.5    Daibata, M.6    Lai, R.7    Wiestner, A.8
  • 53
    • 70349560308 scopus 로고    scopus 로고
    • How I treat mantle cell lymphoma
    • Ghielmini M,Zucca E.How I treat mantle cell lymphoma.Blood. 2009;114:1469-76.
    • (2009) Blood , vol.114 , pp. 1469-1476
    • Ghielmini, M.1    Zucca, E.2
  • 54
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
    • Alessi DR,James SR,Downes CP,Holmes AB,Gaffney PR,Reese CB,Cohen P.Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.Curr Biol. 1997;7:261-9.
    • (1997) Curr Biol , vol.7 , pp. 261-269
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.5    Reese, C.B.6    Cohen, P.7
  • 56
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: navigating downstream
    • Manning BD,Cantley LC.AKT/PKB signaling: navigating downstream.Cell. 2007;129:1261-74.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 58
    • 79957500293 scopus 로고    scopus 로고
    • Stem-like tumor cells confer drug resistant properties to mantle cell lymphoma
    • Jung HJ,Chen Z,McCarty N.Stem-like tumor cells confer drug resistant properties to mantle cell lymphoma.Leuk Lymphoma. 2011;52:1066-79.
    • (2011) Leuk Lymphoma , vol.52 , pp. 1066-1079
    • Jung, H.J.1    Chen, Z.2    McCarty, N.3
  • 60
    • 34249692537 scopus 로고    scopus 로고
    • Rituximab-induced inhibition of antiapoptotic cell survival pathways: implications in chemo/immunoresistance, rituximab unresponsiveness, prognostic and novel therapeutic interventions
    • Bonavida B.Rituximab-induced inhibition of antiapoptotic cell survival pathways: implications in chemo/immunoresistance, rituximab unresponsiveness, prognostic and novel therapeutic interventions.Oncogene. 2007;26:3629-36.
    • (2007) Oncogene , vol.26 , pp. 3629-3636
    • Bonavida, B.1
  • 61
    • 36048935750 scopus 로고    scopus 로고
    • Protein expression and cellular localization in two prognostic subgroups of diffuse large B-cell lymphoma: higher expression of ZAP70 and PKC-beta II in the non-germinal center group and poor survival in patients deficient in nuclear PTEN
    • Fridberg M,Servin A,Anagnostaki L,Linderoth J,Berglund M,Soderberg O,Enblad G,Rosen A,Mustelin T,Jerkeman M,Persson JL,Wingren AG.Protein expression and cellular localization in two prognostic subgroups of diffuse large B-cell lymphoma: higher expression of ZAP70 and PKC-beta II in the non-germinal center group and poor survival in patients deficient in nuclear PTEN.Leuk Lymphoma. 2007;48:2221-32.
    • (2007) Leuk Lymphoma , vol.48 , pp. 2221-2232
    • Fridberg, M.1    Servin, A.2    Anagnostaki, L.3    Linderoth, J.4    Berglund, M.5    Soderberg, O.6    Enblad, G.7    Rosen, A.8    Mustelin, T.9    Jerkeman, M.10    Persson, J.L.11    Wingren, A.G.12
  • 62
    • 77951693077 scopus 로고    scopus 로고
    • High immunohistochemical expression of p-AKT predicts inferior survival in patients with diffuse large B-cell lymphoma treated with immunochemotherapy
    • Hasselblom S,Hansson U,Olsson M,Toren L,Bergstrom A,Nilsson-Ehle H,Andersson PO.High immunohistochemical expression of p-AKT predicts inferior survival in patients with diffuse large B-cell lymphoma treated with immunochemotherapy.Br J Haematol. 2010;149:560-8.
    • (2010) Br J Haematol , vol.149 , pp. 560-568
    • Hasselblom, S.1    Hansson, U.2    Olsson, M.3    Toren, L.4    Bergstrom, A.5    Nilsson-Ehle, H.6    Andersson, P.O.7
  • 64
    • 77954096916 scopus 로고    scopus 로고
    • Leptin receptor expression and its association with PI3K/AKT signaling pathway in diffuse large B-cell lymphoma
    • Uddin S,Bu R,Ahmed M,Hussain AR,Ajarim D,Al-Dayel F,Bavi P,Al-kuraya KS.Leptin receptor expression and its association with PI3K/AKT signaling pathway in diffuse large B-cell lymphoma.Leuk Lymphoma. 2010;51:1305-14.
    • (2010) Leuk Lymphoma , vol.51 , pp. 1305-1314
    • Uddin, S.1    Bu, R.2    Ahmed, M.3    Hussain, A.R.4    Ajarim, D.5    Al-Dayel, F.6    Bavi, P.7    Al-kuraya, K.S.8
  • 65
    • 77956249775 scopus 로고    scopus 로고
    • Inhibition of c-MET is a potential therapeutic strategy for treatment of diffuse large B-cell lymphoma
    • Uddin S,Hussain AR,Ahmed M,Al-Dayel F,Bu R,Bavi P,Al-Kuraya KS.Inhibition of c-MET is a potential therapeutic strategy for treatment of diffuse large B-cell lymphoma.Lab Invest. 2010;90:1346-56.
    • (2010) Lab Invest , vol.90 , pp. 1346-1356
    • Uddin, S.1    Hussain, A.R.2    Ahmed, M.3    Al-Dayel, F.4    Bu, R.5    Bavi, P.6    Al-Kuraya, K.S.7
  • 70
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y,Massague J.Mechanisms of TGF-beta signaling from cell membrane to the nucleus.Cell. 2003;113:685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 71
    • 34250011215 scopus 로고    scopus 로고
    • Resistance to TGF-beta 1 correlates with aberrant expression of TGF-beta receptor II in human B-cell lymphoma cell lines
    • Chen G,Ghosh P,Osawa H,Sasaki CY,Rezanka L,Yang J,O'Farrell TJ,Longo DL.Resistance to TGF-beta 1 correlates with aberrant expression of TGF-beta receptor II in human B-cell lymphoma cell lines.Blood. 2007;109:5301-7.
    • (2007) Blood , vol.109 , pp. 5301-5307
    • Chen, G.1    Ghosh, P.2    Osawa, H.3    Sasaki, C.Y.4    Rezanka, L.5    Yang, J.6    O'Farrell, T.J.7    Longo, D.L.8
  • 72
    • 38849143973 scopus 로고    scopus 로고
    • BCL6 represses Smad signaling in transforming growth factor-beta resistance
    • Wang D,Long J,Dai F,Liang M,Feng XH,Lin X.BCL6 represses Smad signaling in transforming growth factor-beta resistance.Cancer Res. 2008;68:783-9.
    • (2008) Cancer Res , vol.68 , pp. 783-789
    • Wang, D.1    Long, J.2    Dai, F.3    Liang, M.4    Feng, X.H.5    Lin, X.6
  • 74
    • 50349098499 scopus 로고    scopus 로고
    • Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3
    • Allard D,Figg N,Bennett MR,Littlewood TD.Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3.J Biol Chem. 2008;283:19739-47.
    • (2008) J Biol Chem , vol.283 , pp. 19739-19747
    • Allard, D.1    Figg, N.2    Bennett, M.R.3    Littlewood, T.D.4
  • 75
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: a play in three Akts
    • Datta SR,Brunet A,Greenberg ME.Cellular survival: a play in three Akts.Genes Dev. 1999;13:2905-27.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 76
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • del Peso L,Gonzalez-Garcia M,Page C,Herrera R,Nunez G.Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.Science. 1997;278:687-9.
    • (1997) Science , vol.278 , pp. 687-689
    • del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 77
    • 1642410790 scopus 로고    scopus 로고
    • Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation
    • Goldman EH,Chen L,Fu H.Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation.J Biol Chem. 2004;279:10442-9.
    • (2004) J Biol Chem , vol.279 , pp. 10442-10449
    • Goldman, E.H.1    Chen, L.2    Fu, H.3
  • 78
    • 0442276554 scopus 로고    scopus 로고
    • The glamour and gloom of glycogen synthase kinase-3
    • Jope RS,Johnson GV.The glamour and gloom of glycogen synthase kinase-3.Trends Biochem Sci. 2004;29:95-102.
    • (2004) Trends Biochem Sci , vol.29 , pp. 95-102
    • Jope, R.S.1    Johnson, G.V.2
  • 79
    • 59449108481 scopus 로고    scopus 로고
    • Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1
    • Kim I,Shu CW,Xu W,Shiau CW,Grant D,Vasile S,Cosford ND,Reed JC.Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.J Biol Chem. 2009;284:1593-603.
    • (2009) J Biol Chem , vol.284 , pp. 1593-1603
    • Kim, I.1    Shu, C.W.2    Xu, W.3    Shiau, C.W.4    Grant, D.5    Vasile, S.6    Cosford, N.D.7    Reed, J.C.8
  • 81
    • 34249734458 scopus 로고    scopus 로고
    • Rituximab inhibits the constitutively activated PI3K-Akt pathway in B-NHL cell lines: involvement in chemosensitization to drug-induced apoptosis
    • Suzuki E,Umezawa K,Bonavida B.Rituximab inhibits the constitutively activated PI3K-Akt pathway in B-NHL cell lines: involvement in chemosensitization to drug-induced apoptosis.Oncogene. 2007;26:6184-93.
    • (2007) Oncogene , vol.26 , pp. 6184-6193
    • Suzuki, E.1    Umezawa, K.2    Bonavida, B.3
  • 82
    • 79955070726 scopus 로고    scopus 로고
    • Akt, 14-3-3zeta, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma
    • Maxwell SA,Cherry EM,Bayless KJ.Akt, 14-3-3zeta, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma.Leuk Lymphoma. 2011;52:849-64.
    • (2011) Leuk Lymphoma , vol.52 , pp. 849-864
    • Maxwell, S.A.1    Cherry, E.M.2    Bayless, K.J.3
  • 83
    • 69249146105 scopus 로고    scopus 로고
    • 14-3-3zeta mediates resistance of diffuse large B cell lymphoma to an anthracycline-based chemotherapeutic regimen
    • Maxwell SA,Li Z,Jaye D,Ballard S,Ferrell J,Fu H.14-3-3zeta mediates resistance of diffuse large B cell lymphoma to an anthracycline-based chemotherapeutic regimen.J Biol Chem. 2009;284:22379-89.
    • (2009) J Biol Chem , vol.284 , pp. 22379-22389
    • Maxwell, S.A.1    Li, Z.2    Jaye, D.3    Ballard, S.4    Ferrell, J.5    Fu, H.6
  • 84
    • 70449494636 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2
    • Gupta M,Ansell SM,Novak AJ,Kumar S,Kaufmann SH,Witzig TE.Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2.Blood. 2009;114:2926-35.
    • (2009) Blood , vol.114 , pp. 2926-2935
    • Gupta, M.1    Ansell, S.M.2    Novak, A.J.3    Kumar, S.4    Kaufmann, S.H.5    Witzig, T.E.6
  • 87
    • 80755139573 scopus 로고    scopus 로고
    • Targeting the PI3K/AKT/mTOR pathway in non-Hodgkin's lymphoma: results, biology, and development strategies
    • Schatz JH.Targeting the PI3K/AKT/mTOR pathway in non-Hodgkin's lymphoma: results, biology, and development strategies.Curr Oncol Rep. 2011;13:398-406.
    • (2011) Curr Oncol Rep , vol.13 , pp. 398-406
    • Schatz, J.H.1
  • 88
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer PH.CD95's deadly mission in the immune system.Nature. 2000;407:789-95.
    • (2000) Nature , vol.407 , pp. 789-795
    • Krammer, P.H.1
  • 89
    • 0032523201 scopus 로고    scopus 로고
    • Tumor B cells from non-Hodgkin's lymphoma are resistant to CD95 (Fas/Apo-1)-mediated apoptosis
    • Plumas J,Jacob MC,Chaperot L,Molens JP,Sotto JJ,Bensa JC.Tumor B cells from non-Hodgkin's lymphoma are resistant to CD95 (Fas/Apo-1)-mediated apoptosis.Blood. 1998;91:2875-85.
    • (1998) Blood , vol.91 , pp. 2875-2885
    • Plumas, J.1    Jacob, M.C.2    Chaperot, L.3    Molens, J.P.4    Sotto, J.J.5    Bensa, J.C.6
  • 91
    • 12544255082 scopus 로고    scopus 로고
    • Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling
    • Kelley RF,Totpal K,Lindstrom SH,Mathieu M,Billeci K,Deforge L,Pai R,Hymowitz SG,Ashkenazi A.Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling.J Biol Chem. 2005;280:2205-12.
    • (2005) J Biol Chem , vol.280 , pp. 2205-2212
    • Kelley, R.F.1    Totpal, K.2    Lindstrom, S.H.3    Mathieu, M.4    Billeci, K.5    Deforge, L.6    Pai, R.7    Hymowitz, S.G.8    Ashkenazi, A.9
  • 93
    • 0034574306 scopus 로고    scopus 로고
    • The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity
    • Siegel RM,Chan FK,Chun HJ,Lenardo MJ.The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity.Nat Immunol. 2000;1:469-74.
    • (2000) Nat Immunol , vol.1 , pp. 469-474
    • Siegel, R.M.1    Chan, F.K.2    Chun, H.J.3    Lenardo, M.J.4
  • 99
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti RM,Marsters SA,Ruppert S,Donahue CJ,Moore A,Ashkenazi A.Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.J Biol Chem. 1996;271:12687-90.
    • (1996) J Biol Chem , vol.271 , pp. 12687-12690
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5    Ashkenazi, A.6
  • 100
    • 34548161868 scopus 로고    scopus 로고
    • Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis
    • Brien G,Trescol-Biemont MC,Bonnefoy-Berard N.Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis.Oncogene. 2007;26:5828-32.
    • (2007) Oncogene , vol.26 , pp. 5828-5832
    • Brien, G.1    Trescol-Biemont, M.C.2    Bonnefoy-Berard, N.3
  • 101
    • 0033557805 scopus 로고    scopus 로고
    • Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
    • Grumont RJ,Rourke IJ,Gerondakis S.Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis.Genes Dev. 1999;13:400-11.
    • (1999) Genes Dev , vol.13 , pp. 400-411
    • Grumont, R.J.1    Rourke, I.J.2    Gerondakis, S.3
  • 102
    • 0032588317 scopus 로고    scopus 로고
    • NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis
    • Wang CY,Guttridge DC,Mayo MW,Baldwin AS.NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis.Mol Cell Biol. 1999;19:5923-9.
    • (1999) Mol Cell Biol , vol.19 , pp. 5923-5929
    • Wang, C.Y.1    Guttridge, D.C.2    Mayo, M.W.3    Baldwin, A.S.4
  • 103
    • 0033558215 scopus 로고    scopus 로고
    • The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis
    • Zong WX,Edelstein LC,Chen C,Bash J,Gelinas C.The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis.Genes Dev. 1999;13:382-7.
    • (1999) Genes Dev , vol.13 , pp. 382-387
    • Zong, W.X.1    Edelstein, L.C.2    Chen, C.3    Bash, J.4    Gelinas, C.5
  • 104
    • 0037151030 scopus 로고    scopus 로고
    • Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax
    • Werner AB,de Vries E,Tait SW,Bontjer I,Borst J.Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.J Biol Chem. 2002;277:22781-8.
    • (2002) J Biol Chem , vol.277 , pp. 22781-22788
    • Werner, A.B.1    de Vries, E.2    Tait, S.W.3    Bontjer, I.4    Borst, J.5
  • 106
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: critical control points
    • Danial NN,Korsmeyer SJ.Cell death: critical control points.Cell. 2004;116:205-19.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 107
    • 32644473650 scopus 로고    scopus 로고
    • How the Bcl-2 family of proteins interact to regulate apoptosis
    • van Delft MF,Huang DC.How the Bcl-2 family of proteins interact to regulate apoptosis.Cell Res. 2006;16:203-13.
    • (2006) Cell Res , vol.16 , pp. 203-213
    • van Delft, M.F.1    Huang, D.C.2
  • 108
    • 0036097786 scopus 로고    scopus 로고
    • Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
    • Puthalakath H,Strasser A.Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins.Cell Death Differ. 2002;9:505-12.
    • (2002) Cell Death Differ , vol.9 , pp. 505-512
    • Puthalakath, H.1    Strasser, A.2
  • 109
    • 18544385191 scopus 로고    scopus 로고
    • Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance
    • Sun Y,Orrenius S,Pervaiz S,Fadeel B.Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance.Blood. 2005;105:4070-7.
    • (2005) Blood , vol.105 , pp. 4070-4077
    • Sun, Y.1    Orrenius, S.2    Pervaiz, S.3    Fadeel, B.4
  • 110
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: a link between cancer genetics and chemotherapy
    • Johnstone RW,Ruefli AA,Lowe SW.Apoptosis: a link between cancer genetics and chemotherapy.Cell. 2002;108:153-64.
    • (2002) Cell , vol.108 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 111
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed JC.Bcl-2 and the regulation of programmed cell death.J Cell Biol. 1994;124:1-6.
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 112
    • 0037199456 scopus 로고    scopus 로고
    • Peptides derived from BH3 domains of Bcl-2 family members: a comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release, and activation of cell death
    • Shangary S,Johnson DE.Peptides derived from BH3 domains of Bcl-2 family members: a comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release, and activation of cell death.Biochemistry. 2002;41:9485-95.
    • (2002) Biochemistry , vol.41 , pp. 9485-9495
    • Shangary, S.1    Johnson, D.E.2
  • 115
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
    • Kluck RM,Bossy-Wetzel E,Green DR,Newmeyer DD.The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis.Science. 1997;275:1132-6.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 116
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: a discourse on the BCL2 family and cell death
    • Yang E,Korsmeyer SJ.Molecular thanatopsis: a discourse on the BCL2 family and cell death.Blood. 1996;88:386-401.
    • (1996) Blood , vol.88 , pp. 386-401
    • Yang, E.1    Korsmeyer, S.J.2
  • 122
    • 15244355253 scopus 로고    scopus 로고
    • Bcl-2 antisense therapy in B-cell malignancies
    • Chanan-Khan A.Bcl-2 antisense therapy in B-cell malignancies.Blood Rev. 2005;19:213-21.
    • (2005) Blood Rev , vol.19 , pp. 213-221
    • Chanan-Khan, A.1
  • 123
    • 0034015672 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma
    • Waters JS,Webb A,Cunningham D,Clarke PA,Raynaud F,di Stefano F,Cotter FE.Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma.J Clin Oncol. 2000;18:1812-23.
    • (2000) J Clin Oncol , vol.18 , pp. 1812-1823
    • Waters, J.S.1    Webb, A.2    Cunningham, D.3    Clarke, P.A.4    Raynaud, F.5    di Stefano, F.6    Cotter, F.E.7
  • 124
    • 0028060247 scopus 로고
    • Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression
    • Kitada S,Takayama S,De Riel K,Tanaka S,Reed JC.Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression.Antisense Res Dev. 1994;4:71-9.
    • (1994) Antisense Res Dev , vol.4 , pp. 71-79
    • Kitada, S.1    Takayama, S.2    de Riel, K.3    Tanaka, S.4    Reed, J.C.5
  • 126
    • 0033009890 scopus 로고    scopus 로고
    • The central effectors of cell death in the immune system
    • Rathmell JC,Thompson CB.The central effectors of cell death in the immune system.Annu Rev Immunol. 1999;17:781-828.
    • (1999) Annu Rev Immunol , vol.17 , pp. 781-828
    • Rathmell, J.C.1    Thompson, C.B.2
  • 133
    • 0037097598 scopus 로고    scopus 로고
    • Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes
    • Korz C,Pscherer A,Benner A,Mertens D,Schaffner C,Leupolt E,Dohner H,Stilgenbauer S,Lichter P.Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes.Blood. 2002;99:4554-61.
    • (2002) Blood , vol.99 , pp. 4554-4561
    • Korz, C.1    Pscherer, A.2    Benner, A.3    Mertens, D.4    Schaffner, C.5    Leupolt, E.6    Dohner, H.7    Stilgenbauer, S.8    Lichter, P.9
  • 137
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
    • Baldwin AS.Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.J Clin Invest. 2001;107:241-6.
    • (2001) J Clin Invest , vol.107 , pp. 241-246
    • Baldwin, A.S.1
  • 138
    • 33947586159 scopus 로고    scopus 로고
    • Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications
    • Jost PJ,Ruland J.Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications.Blood. 2007;109:2700-7.
    • (2007) Blood , vol.109 , pp. 2700-2707
    • Jost, P.J.1    Ruland, J.2
  • 139
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden MS,Ghosh S.Signaling to NF-kappaB.Genes Dev. 2004;18:2195-224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 140
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M.Nuclear factor-kappaB in cancer development and progression.Nature. 2006;441:431-6.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 141
    • 33645999706 scopus 로고    scopus 로고
    • NF-kappaB and IKK as therapeutic targets in cancer
    • Kim HJ,Hawke N,Baldwin AS.NF-kappaB and IKK as therapeutic targets in cancer.Cell Death Differ. 2006;13:738-47.
    • (2006) Cell Death Differ , vol.13 , pp. 738-747
    • Kim, H.J.1    Hawke, N.2    Baldwin, A.S.3
  • 142
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-kappaB signaling: balancing life and death - a new approach to cancer therapy
    • Luo JL,Kamata H,Karin M.IKK/NF-kappaB signaling: balancing life and death - a new approach to cancer therapy.J Clin Invest. 2005;115:2625-32.
    • (2005) J Clin Invest , vol.115 , pp. 2625-2632
    • Luo, J.L.1    Kamata, H.2    Karin, M.3
  • 143
    • 4944264724 scopus 로고    scopus 로고
    • Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab
    • Jazirehi AR,Vega MI,Chatterjee D,Goodglick L,Bonavida B.Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab.Cancer Res. 2004;64:7117-26.
    • (2004) Cancer Res , vol.64 , pp. 7117-7126
    • Jazirehi, A.R.1    Vega, M.I.2    Chatterjee, D.3    Goodglick, L.4    Bonavida, B.5
  • 144
    • 28144441981 scopus 로고    scopus 로고
    • Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies
    • Thomas RK,Sos ML,Zander T,Mani O,Popov A,Berenbrinker D,Smola-Hess S,Schultze JL,Wolf J.Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies.Clin Cancer Res. 2005;11:8186-94.
    • (2005) Clin Cancer Res , vol.11 , pp. 8186-8194
    • Thomas, R.K.1    Sos, M.L.2    Zander, T.3    Mani, O.4    Popov, A.5    Berenbrinker, D.6    Smola-Hess, S.7    Schultze, J.L.8    Wolf, J.9
  • 145
    • 84882565977 scopus 로고    scopus 로고
    • MicroRNA-21 regulates the sensitivity of diffuse large B-cell lymphoma cells to the CHOP chemotherapy regimen
    • Bai H,Wei J,Deng C,Yang X,Wang C,Xu R.MicroRNA-21 regulates the sensitivity of diffuse large B-cell lymphoma cells to the CHOP chemotherapy regimen.Int J Hematol. 2013;97:223-31.
    • (2013) Int J Hematol , vol.97 , pp. 223-231
    • Bai, H.1    Wei, J.2    Deng, C.3    Yang, X.4    Wang, C.5    Xu, R.6
  • 148
    • 2342449399 scopus 로고    scopus 로고
    • Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma
    • Ota A,Tagawa H,Karnan S,Tsuzuki S,Karpas A,Kira S,Yoshida Y,Seto M.Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma.Cancer Res. 2004;64:3087-95.
    • (2004) Cancer Res , vol.64 , pp. 3087-3095
    • Ota, A.1    Tagawa, H.2    Karnan, S.3    Tsuzuki, S.4    Karpas, A.5    Kira, S.6    Yoshida, Y.7    Seto, M.8
  • 151
    • 0035866773 scopus 로고    scopus 로고
    • Catalase-overexpressing thymocytes are resistant to glucocorticoid-induced apoptosis and exhibit increased net tumor growth
    • Tome ME,Baker AF,Powis G,Payne CM,Briehl MM.Catalase-overexpressing thymocytes are resistant to glucocorticoid-induced apoptosis and exhibit increased net tumor growth.Cancer Res. 2001;61:2766-73.
    • (2001) Cancer Res , vol.61 , pp. 2766-2773
    • Tome, M.E.1    Baker, A.F.2    Powis, G.3    Payne, C.M.4    Briehl, M.M.5
  • 152
    • 0034844584 scopus 로고    scopus 로고
    • Thymocytes selected for resistance to hydrogen peroxide show altered antioxidant enzyme profiles and resistance to dexamethasone-induced apoptosis
    • Tome ME,Briehl MM.Thymocytes selected for resistance to hydrogen peroxide show altered antioxidant enzyme profiles and resistance to dexamethasone-induced apoptosis.Cell Death Differ. 2001;8:953-61.
    • (2001) Cell Death Differ , vol.8 , pp. 953-961
    • Tome, M.E.1    Briehl, M.M.2
  • 155
    • 3242754314 scopus 로고    scopus 로고
    • Overexpression of catalase or Bcl-2 alters glucose and energy metabolism concomitant with dexamethasone resistance
    • Tome ME,Lutz NW,Briehl MM.Overexpression of catalase or Bcl-2 alters glucose and energy metabolism concomitant with dexamethasone resistance.Biochim Biophys Acta. 2004;1693:57-72.
    • (2004) Biochim Biophys Acta , vol.1693 , pp. 57-72
    • Tome, M.E.1    Lutz, N.W.2    Briehl, M.M.3
  • 159
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby RA,Gillies RJ.Why do cancers have high aerobic glycolysis?.Nat Rev Cancer. 2004;4:891 9-9.
    • (2004) Nat Rev Cancer , vol.4 , pp. 8919
    • Gatenby, R.A.1    Gillies, R.J.2
  • 161
    • 33847377377 scopus 로고    scopus 로고
    • Tumor acidity, chemoresistance and proton pump inhibitors
    • De Milito A,Fais S.Tumor acidity, chemoresistance and proton pump inhibitors.Future Oncol. 2005;1:779-86.
    • (2005) Future Oncol , vol.1 , pp. 779-786
    • de Milito, A.1    Fais, S.2
  • 162
    • 0042242676 scopus 로고    scopus 로고
    • The glycolytic phenotype in carcinogenesis and tumor invasion: insights through mathematical models
    • Gatenby RA,Gawlinski ET.The glycolytic phenotype in carcinogenesis and tumor invasion: insights through mathematical models.Cancer Res. 2003;63:3847-54.
    • (2003) Cancer Res , vol.63 , pp. 3847-3854
    • Gatenby, R.A.1    Gawlinski, E.T.2
  • 165
    • 0029954846 scopus 로고    scopus 로고
    • Glutathione and related enzymes in multidrug resistance
    • O'Brien ML,Tew KD.Glutathione and related enzymes in multidrug resistance.Eur J Cancer A. 1996;32:967-78.
    • (1996) Eur J Cancer A , vol.32 , pp. 967-978
    • O'Brien, M.L.1    Tew, K.D.2
  • 166
    • 0038134267 scopus 로고
    • Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats
    • Cowan KH,Batist G,Tulpule A,Sinha BK,Myers CE.Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats.Proc Natl Acad Sci USA. 1986;83:9328-32.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 9328-9332
    • Cowan, K.H.1    Batist, G.2    Tulpule, A.3    Sinha, B.K.4    Myers, C.E.5
  • 167
    • 0022536174 scopus 로고
    • A proposed mechanism of resistance to cyclophosphamide and phosphoramide mustard in a Yoshida cell line in vitro
    • McGown AT,Fox BW.A proposed mechanism of resistance to cyclophosphamide and phosphoramide mustard in a Yoshida cell line in vitro.Cancer Chemother Pharmacol. 1986;17:223-6.
    • (1986) Cancer Chemother Pharmacol , vol.17 , pp. 223-226
    • McGown, A.T.1    Fox, B.W.2
  • 168
    • 0023554666 scopus 로고
    • Reduced levels of drug-induced DNA cross-linking in nitrogen mustard-resistant Chinese hamster ovary cells expressing elevated glutathione S-transferase activity
    • Robson CN,Lewis AD,Wolf CR,Hayes JD,Hall A,Proctor SJ,Harris AL,Hickson ID.Reduced levels of drug-induced DNA cross-linking in nitrogen mustard-resistant Chinese hamster ovary cells expressing elevated glutathione S-transferase activity.Cancer Res. 1987;47:6022-7.
    • (1987) Cancer Res , vol.47 , pp. 6022-6027
    • Robson, C.N.1    Lewis, A.D.2    Wolf, C.R.3    Hayes, J.D.4    Hall, A.5    Proctor, S.J.6    Harris, A.L.7    Hickson, I.D.8
  • 169
    • 0025303623 scopus 로고
    • Characterization of glutathione S-transferase expression in lymphocytes from chronic lymphocytic leukemia patients
    • Schisselbauer JC,Silber R,Papadopoulos E,Abrams K,LaCreta FP,Tew KD.Characterization of glutathione S-transferase expression in lymphocytes from chronic lymphocytic leukemia patients.Cancer Res. 1990;50:3562-8.
    • (1990) Cancer Res , vol.50 , pp. 3562-3568
    • Schisselbauer, J.C.1    Silber, R.2    Papadopoulos, E.3    Abrams, K.4    LaCreta, F.P.5    Tew, K.D.6
  • 171
    • 0028106016 scopus 로고
    • Glutathione-associated enzymes in anticancer drug resistance
    • Tew KD.Glutathione-associated enzymes in anticancer drug resistance.Cancer Res. 1994;54:4313-20.
    • (1994) Cancer Res , vol.54 , pp. 4313-4320
    • Tew, K.D.1
  • 175
    • 33748655239 scopus 로고    scopus 로고
    • Effect of rituximab on the long-term outcome after high-dose therapy for relapsed B-cell non-Hodgkin's lymphoma
    • Hess G,Flohr T,Kolbe K,Bonn S,Schuler M,Derigs HG,Huber C.Effect of rituximab on the long-term outcome after high-dose therapy for relapsed B-cell non-Hodgkin's lymphoma.Ann Hematol. 2006;85:769-79.
    • (2006) Ann Hematol , vol.85 , pp. 769-779
    • Hess, G.1    Flohr, T.2    Kolbe, K.3    Bonn, S.4    Schuler, M.5    Derigs, H.G.6    Huber, C.7
  • 180
    • 0028127304 scopus 로고
    • Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma
    • Maloney DG,Liles TM,Czerwinski DK,Waldichuk C,Rosenberg J,Grillo-Lopez A,Levy R.Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma.Blood. 1994;84:2457-66.
    • (1994) Blood , vol.84 , pp. 2457-2466
    • Maloney, D.G.1    Liles, T.M.2    Czerwinski, D.K.3    Waldichuk, C.4    Rosenberg, J.5    Grillo-Lopez, A.6    Levy, R.7
  • 182
    • 0023976470 scopus 로고
    • Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains
    • Einfeld DA,Brown JP,Valentine MA,Clark EA,Ledbetter JA.Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains.EMBO J. 1988;7:711-17.
    • (1988) EMBO J , vol.7 , pp. 711-717
    • Einfeld, D.A.1    Brown, J.P.2    Valentine, M.A.3    Clark, E.A.4    Ledbetter, J.A.5
  • 183
    • 27544508559 scopus 로고    scopus 로고
    • Tolerability and safety of rituximab (MabThera)
    • Kimby E.Tolerability and safety of rituximab (MabThera).Cancer Treat Rev. 2005;31:456-73.
    • (2005) Cancer Treat Rev , vol.31 , pp. 456-473
    • Kimby, E.1
  • 184
    • 0642312825 scopus 로고    scopus 로고
    • Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance
    • Smith MR.Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance.Oncogene. 2003;22:7359-68.
    • (2003) Oncogene , vol.22 , pp. 7359-7368
    • Smith, M.R.1
  • 185
    • 34948866757 scopus 로고    scopus 로고
    • Phase I to III trials of anti-B cell therapy in non-Hodgkin's lymphoma
    • Martin P,Furman RR,Coleman M,Leonard JP.Phase I to III trials of anti-B cell therapy in non-Hodgkin's lymphoma.Clin Cancer Res. 2007;13:5636s-42s.
    • (2007) Clin Cancer Res , vol.13
    • Martin, P.1    Furman, R.R.2    Coleman, M.3    Leonard, J.P.4
  • 186
    • 34249821912 scopus 로고    scopus 로고
    • Rituximab therapy in malignant lymphoma
    • Coiffier B.Rituximab therapy in malignant lymphoma.Oncogene. 2007;26:3603-13.
    • (2007) Oncogene , vol.26 , pp. 3603-3613
    • Coiffier, B.1
  • 190
    • 14544276412 scopus 로고    scopus 로고
    • Maximizing therapeutic benefit of rituximab: maintenance therapy versus re-treatment at progression in patients with indolent non-Hodgkin's lymphoma - a randomized phase II trial of the Minnie Pearl Cancer Research Network
    • Hainsworth JD,Litchy S,Shaffer DW,Lackey VL,Grimaldi M,Greco FA.Maximizing therapeutic benefit of rituximab: maintenance therapy versus re-treatment at progression in patients with indolent non-Hodgkin's lymphoma - a randomized phase II trial of the Minnie Pearl Cancer Research Network.J Clin Oncol. 2005;23:1088-95.
    • (2005) J Clin Oncol , vol.23 , pp. 1088-1095
    • Hainsworth, J.D.1    Litchy, S.2    Shaffer, D.W.3    Lackey, V.L.4    Grimaldi, M.5    Greco, F.A.6
  • 193
    • 27244440161 scopus 로고    scopus 로고
    • Immunotherapy for non-Hodgkin's lymphoma: monoclonal antibodies and vaccines
    • Maloney DG.Immunotherapy for non-Hodgkin's lymphoma: monoclonal antibodies and vaccines.J Clin Oncol. 2005;23:6421-8.
    • (2005) J Clin Oncol , vol.23 , pp. 6421-6428
    • Maloney, D.G.1
  • 194
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
    • Clynes RA,Towers TL,Presta LG,Ravetch JV.Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets.Nat Med. 2000;6:443-6.
    • (2000) Nat Med , vol.6 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 195
    • 0036441027 scopus 로고    scopus 로고
    • Incidence and nature of CD20-negative relapses following rituximab therapy in aggressive B-cell non-Hodgkin's lymphoma: a retrospective review
    • Kennedy GA,Tey SK,Cobcroft R,Marlton P,Cull G,Grimmett K,Thomson D,Gill D.Incidence and nature of CD20-negative relapses following rituximab therapy in aggressive B-cell non-Hodgkin's lymphoma: a retrospective review.Br J Haematol. 2002;119:412-6.
    • (2002) Br J Haematol , vol.119 , pp. 412-416
    • Kennedy, G.A.1    Tey, S.K.2    Cobcroft, R.3    Marlton, P.4    Cull, G.5    Grimmett, K.6    Thomson, D.7    Gill, D.8
  • 196
    • 33745017226 scopus 로고    scopus 로고
    • Caspase-independent killing of Burkitt lymphoma cell lines by rituximab
    • Daniels I,Abulayha AM,Thomson BJ,Haynes AP.Caspase-independent killing of Burkitt lymphoma cell lines by rituximab.Apoptosis. 2006;11:1013-23.
    • (2006) Apoptosis , vol.11 , pp. 1013-1023
    • Daniels, I.1    Abulayha, A.M.2    Thomson, B.J.3    Haynes, A.P.4
  • 197
    • 0033855194 scopus 로고    scopus 로고
    • Clustered CD20 induced apoptosis: src-family kinase, the proximal regulator of tyrosine phosphorylation, calcium influx, and caspase 3-dependent apoptosis
    • Hofmeister JK,Cooney D,Coggeshall KM.Clustered CD20 induced apoptosis: src-family kinase, the proximal regulator of tyrosine phosphorylation, calcium influx, and caspase 3-dependent apoptosis.Blood Cells Mol Dis. 2000;26:133-43.
    • (2000) Blood Cells Mol Dis , vol.26 , pp. 133-143
    • Hofmeister, J.K.1    Cooney, D.2    Coggeshall, K.M.3
  • 198
    • 0031858988 scopus 로고    scopus 로고
    • The association between CD20 and Src-family Tyrosine kinases requires an additional factor
    • Popoff IJ,Savage JA,Blake J,Johnson P,Deans JP.The association between CD20 and Src-family Tyrosine kinases requires an additional factor.Mol Immunol. 1998;35:207-14.
    • (1998) Mol Immunol , vol.35 , pp. 207-214
    • Popoff, I.J.1    Savage, J.A.2    Blake, J.3    Johnson, P.4    Deans, J.P.5
  • 199
    • 0032030699 scopus 로고    scopus 로고
    • Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies
    • Shan D,Ledbetter JA,Press OW.Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies.Blood. 1998;91:1644-52.
    • (1998) Blood , vol.91 , pp. 1644-1652
    • Shan, D.1    Ledbetter, J.A.2    Press, O.W.3
  • 200
    • 0034104375 scopus 로고    scopus 로고
    • Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells
    • Shan D,Ledbetter JA,Press OW.Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells.Cancer Immunol Immunother. 2000;48:673-83.
    • (2000) Cancer Immunol Immunother , vol.48 , pp. 673-683
    • Shan, D.1    Ledbetter, J.A.2    Press, O.W.3
  • 202
    • 40949083386 scopus 로고    scopus 로고
    • Acquired resistance to rituximab is associated with chemotherapy resistance resulting from decreased Bax and Bak expression
    • Olejniczak SH,Hernandez-Ilizaliturri FJ,Clements JL,Czuczman MS.Acquired resistance to rituximab is associated with chemotherapy resistance resulting from decreased Bax and Bak expression.Clin Cancer Res. 2008;14:1550-60.
    • (2008) Clin Cancer Res , vol.14 , pp. 1550-1560
    • Olejniczak, S.H.1    Hernandez-Ilizaliturri, F.J.2    Clements, J.L.3    Czuczman, M.S.4
  • 203
    • 8444248590 scopus 로고    scopus 로고
    • Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression
    • Davidson B,Konstantinovsky S,Nielsen S,Dong HP,Berner A,Vyberg M,Reich R.Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.Clin Cancer Res. 2004;10:7335-46.
    • (2004) Clin Cancer Res , vol.10 , pp. 7335-7346
    • Davidson, B.1    Konstantinovsky, S.2    Nielsen, S.3    Dong, H.P.4    Berner, A.5    Vyberg, M.6    Reich, R.7
  • 204
    • 15244344671 scopus 로고    scopus 로고
    • EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair
    • Gabison EE,Hoang-Xuan T,Mauviel A,Menashi S.EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair.Biochimie. 2005;87:361-8.
    • (2005) Biochimie , vol.87 , pp. 361-368
    • Gabison, E.E.1    Hoang-Xuan, T.2    Mauviel, A.3    Menashi, S.4
  • 205
    • 0037478612 scopus 로고    scopus 로고
    • Regulation of multidrug resistance in cancer cells by hyaluronan
    • Misra S,Ghatak S,Zoltan-Jones A,Toole BP.Regulation of multidrug resistance in cancer cells by hyaluronan.J Biol Chem. 2003;278:25285-8.
    • (2003) J Biol Chem , vol.278 , pp. 25285-25288
    • Misra, S.1    Ghatak, S.2    Zoltan-Jones, A.3    Toole, B.P.4
  • 207
    • 33847263980 scopus 로고    scopus 로고
    • Inhibition of CD147 gene expression via RNA interference reduces tumor cell invasion, tumorigenicity and increases chemosensitivity to paclitaxel in HO-8910pm cells
    • Zou W,Yang H,Hou X,Zhang W,Chen B,Xin X.Inhibition of CD147 gene expression via RNA interference reduces tumor cell invasion, tumorigenicity and increases chemosensitivity to paclitaxel in HO-8910pm cells.Cancer Lett. 2007;248:211-8.
    • (2007) Cancer Lett , vol.248 , pp. 211-218
    • Zou, W.1    Yang, H.2    Hou, X.3    Zhang, W.4    Chen, B.5    Xin, X.6
  • 210
    • 67649390889 scopus 로고    scopus 로고
    • Silencing CD147 inhibits tumor progression and increases chemosensitivity in murine lymphoid neoplasm P388D1 cells
    • Jia L,Wei W,Cao J,Xu H,Miao X,Zhang J.Silencing CD147 inhibits tumor progression and increases chemosensitivity in murine lymphoid neoplasm P388D1 cells.Ann Hematol. 2009;88:753-60.
    • (2009) Ann Hematol , vol.88 , pp. 753-760
    • Jia, L.1    Wei, W.2    Cao, J.3    Xu, H.4    Miao, X.5    Zhang, J.6
  • 211
    • 0028224534 scopus 로고
    • Cell biological mechanisms of multidrug resistance in tumors
    • Simon SM,Schindler M.Cell biological mechanisms of multidrug resistance in tumors.Proc Natl Acad Sci USA. 1994;91:3497-504.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3497-3504
    • Simon, S.M.1    Schindler, M.2
  • 212
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM,Pastan I.Biochemistry of multidrug resistance mediated by the multidrug transporter.Annu Rev Biochem. 1993;62:385-427.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 213
    • 0034936354 scopus 로고    scopus 로고
    • ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2
    • Kerb R,Hoffmeyer S,Brinkmann U.ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2.Pharmacogenomics. 2001;2:51-64.
    • (2001) Pharmacogenomics , vol.2 , pp. 51-64
    • Kerb, R.1    Hoffmeyer, S.2    Brinkmann, U.3
  • 214
    • 0034947674 scopus 로고    scopus 로고
    • From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
    • Litman T,Druley TE,Stein WD,Bates SE.From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.Cell Mol Life Sci. 2001;58:931-59.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 931-959
    • Litman, T.1    Druley, T.E.2    Stein, W.D.3    Bates, S.E.4
  • 218
    • 23844471567 scopus 로고    scopus 로고
    • Immunohistochemical expression of multidrug resistance proteins as a predictor of poor response to chemotherapy and prognosis in patients with nodal diffuse large B-cell lymphoma
    • Ohsawa M,Ikura Y,Fukushima H,Shirai N,Sugama Y,Suekane T,Hirayama M,Hino M,Ueda M.Immunohistochemical expression of multidrug resistance proteins as a predictor of poor response to chemotherapy and prognosis in patients with nodal diffuse large B-cell lymphoma.Oncology. 2005;68:422-31.
    • (2005) Oncology , vol.68 , pp. 422-431
    • Ohsawa, M.1    Ikura, Y.2    Fukushima, H.3    Shirai, N.4    Sugama, Y.5    Suekane, T.6    Hirayama, M.7    Hino, M.8    Ueda, M.9
  • 220
    • 0026051296 scopus 로고
    • P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil
    • Miller TP,Grogan TM,Dalton WS,Spier CM,Scheper RJ,Salmon SE.P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil.J Clin Oncol. 1991;9:17-24.
    • (1991) J Clin Oncol , vol.9 , pp. 17-24
    • Miller, T.P.1    Grogan, T.M.2    Dalton, W.S.3    Spier, C.M.4    Scheper, R.J.5    Salmon, S.E.6
  • 223
    • 0027458768 scopus 로고
    • Expression of P-glycoprotein and anionic glutathione S-transferase genes in non-Hodgkin's lymphoma
    • Rodriguez C,Commes T,Robert J,Rossi JF.Expression of P-glycoprotein and anionic glutathione S-transferase genes in non-Hodgkin's lymphoma.Leuk Res. 1993;17:149-56.
    • (1993) Leuk Res , vol.17 , pp. 149-156
    • Rodriguez, C.1    Commes, T.2    Robert, J.3    Rossi, J.F.4
  • 224
    • 0029164766 scopus 로고
    • MDR-1 expression in non-Hodgkin's lymphomas is unrelated to treatment intensity or response to therapy
    • Finnegan MC,Royds J,Goepel JR,Lorigan P,Hancock BW,Goyns MH.MDR-1 expression in non-Hodgkin's lymphomas is unrelated to treatment intensity or response to therapy.Leuk Lymphoma. 1995;18:297-302.
    • (1995) Leuk Lymphoma , vol.18 , pp. 297-302
    • Finnegan, M.C.1    Royds, J.2    Goepel, J.R.3    Lorigan, P.4    Hancock, B.W.5    Goyns, M.H.6
  • 225
    • 0030915104 scopus 로고    scopus 로고
    • Expression of the multidrug resistance-associated protein gene in refractory lymphoma: quantitation by a validated polymerase chain reaction assay
    • Zhan Z,Sandor VA,Gamelin E,Regis J,Dickstein B,Wilson W,Fojo AT,Bates SE.Expression of the multidrug resistance-associated protein gene in refractory lymphoma: quantitation by a validated polymerase chain reaction assay.Blood. 1997;89:3795-800.
    • (1997) Blood , vol.89 , pp. 3795-3800
    • Zhan, Z.1    Sandor, V.A.2    Gamelin, E.3    Regis, J.4    Dickstein, B.5    Wilson, W.6    Fojo, A.T.7    Bates, S.E.8
  • 227
    • 0026781491 scopus 로고
    • Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas
    • Holzmayer TA,Hilsenbeck S,Von Hoff DD,Roninson IB.Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas.J Natl Cancer Inst. 1992;84:1486-91.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1486-1491
    • Holzmayer, T.A.1    Hilsenbeck, S.2    von Hoff, D.D.3    Roninson, I.B.4
  • 228
    • 56949101068 scopus 로고    scopus 로고
    • PI3K/Akt inhibition modulates multidrug resistance and activates NF-kappaB in murine lymphoma cell lines
    • Garcia MG,Alaniz LD,Russo RIC,Alvarez E,Hajos SE.PI3K/Akt inhibition modulates multidrug resistance and activates NF-kappaB in murine lymphoma cell lines.Leuk Res. 2009;33:288-96.
    • (2009) Leuk Res , vol.33 , pp. 288-296
    • Garcia, M.G.1    Alaniz, L.D.2    Russo, R.I.C.3    Alvarez, E.4    Hajos, S.E.5
  • 230
    • 82955237344 scopus 로고    scopus 로고
    • ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma
    • Singh RR,Kunkalla K,Qu C,Schlette E,Neelapu SS,Samaniego F,Vega F.ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma.Oncogene. 2011;30:4874-86.
    • (2011) Oncogene , vol.30 , pp. 4874-4886
    • Singh, R.R.1    Kunkalla, K.2    Qu, C.3    Schlette, E.4    Neelapu, S.S.5    Samaniego, F.6    Vega, F.7
  • 233
    • 0023003549 scopus 로고
    • Isolation and characterization of a novel ribonucleoprotein particle: large structures contain a single species of small RNA
    • Kedersha NL,Rome LH.Isolation and characterization of a novel ribonucleoprotein particle: large structures contain a single species of small RNA.J Cell Biol. 1986;103:699-709.
    • (1986) J Cell Biol , vol.103 , pp. 699-709
    • Kedersha, N.L.1    Rome, L.H.2
  • 237
    • 0022551962 scopus 로고    scopus 로고
    • Evidence for the metabolism of mitozantrone by microsomal glutathione transferases and 3-methylcholanthrene-inducible glucuronosyl transferases
    • Wolf CR,Macpherson JS,Smyth JF.Evidence for the metabolism of mitozantrone by microsomal glutathione transferases and 3-methylcholanthrene-inducible glucuronosyl transferases.Biochem Pharmacol. 35:1577-81.
    • Biochem Pharmacol , vol.35 , pp. 1577-1581
    • Wolf, C.R.1    Macpherson, J.S.2    Smyth, J.F.3
  • 238
    • 0023037085 scopus 로고
    • Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells
    • Batist G,Tulpule A,Sinha BK,Katki AG,Myers CE,Cowan KH.Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.J Biol Chem. 1986;261:15544-9.
    • (1986) J Biol Chem , vol.261 , pp. 15544-15549
    • Batist, G.1    Tulpule, A.2    Sinha, B.K.3    Katki, A.G.4    Myers, C.E.5    Cowan, K.H.6
  • 239
    • 0024322933 scopus 로고
    • Glutathione and glutathione S-transferases in a human plasma cell line resistant to melphalan
    • Gupta V,Singh SV,Ahmad H,Medh RD,Awasthi YC.Glutathione and glutathione S-transferases in a human plasma cell line resistant to melphalan.Biochem Pharmacol. 1989;38:1993-2000.
    • (1989) Biochem Pharmacol , vol.38 , pp. 1993-2000
    • Gupta, V.1    Singh, S.V.2    Ahmad, H.3    Medh, R.D.4    Awasthi, Y.C.5
  • 240
    • 0025760337 scopus 로고
    • Specificity of isozymes of murine hepatic glutathione S-transferase for the conjugation of glutathione with L-phenylalanine mustard
    • Bolton MG,Colvin OM,Hilton J.Specificity of isozymes of murine hepatic glutathione S-transferase for the conjugation of glutathione with L-phenylalanine mustard.Cancer Res. 1991;51:2410-5.
    • (1991) Cancer Res , vol.51 , pp. 2410-2415
    • Bolton, M.G.1    Colvin, O.M.2    Hilton, J.3
  • 242
    • 0025317653 scopus 로고
    • Expression of recombinant glutathione S-transferase pi, Ya, or Yb1 confers resistance to alkylating agents
    • Puchalski RB,Fahl WE.Expression of recombinant glutathione S-transferase pi, Ya, or Yb1 confers resistance to alkylating agents.Proc Natl Acad Sci USA. 1990;87:2443-7.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2443-2447
    • Puchalski, R.B.1    Fahl, W.E.2
  • 245
    • 0035419289 scopus 로고    scopus 로고
    • Differential induction of apoptosis and MAP kinase signaling by mitochondrial toxicants in drug-sensitive compared to drug-resistant B-lineage lymphoid cell lines
    • O'Brien KA,Muscarella DE,Bloom SE.Differential induction of apoptosis and MAP kinase signaling by mitochondrial toxicants in drug-sensitive compared to drug-resistant B-lineage lymphoid cell lines.Toxicol Appl Pharmacol. 2001;174:245-56.
    • (2001) Toxicol Appl Pharmacol , vol.174 , pp. 245-256
    • O'Brien, K.A.1    Muscarella, D.E.2    Bloom, S.E.3
  • 246
    • 0035504078 scopus 로고    scopus 로고
    • Expression of the oncogenic NPM-ALK chimeric protein in human lymphoid T-cells inhibits drug-induced, but not Fas-induced apoptosis
    • Greenland C,Touriol C,Chevillard G,Morris SW,Bai R,Duyster J,Delsol G,Allouche M.Expression of the oncogenic NPM-ALK chimeric protein in human lymphoid T-cells inhibits drug-induced, but not Fas-induced apoptosis.Oncogene. 2001;20:7386-97.
    • (2001) Oncogene , vol.20 , pp. 7386-7397
    • Greenland, C.1    Touriol, C.2    Chevillard, G.3    Morris, S.W.4    Bai, R.5    Duyster, J.6    Delsol, G.7    Allouche, M.8
  • 247
    • 0034678609 scopus 로고    scopus 로고
    • Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia
    • Liu Q,Schwaller J,Kutok J,Cain D,Aster JC,Williams IR,Gilliland DG.Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia.EMBO J. 2000;19:1827-38.
    • (2000) EMBO J , vol.19 , pp. 1827-1838
    • Liu, Q.1    Schwaller, J.2    Kutok, J.3    Cain, D.4    Aster, J.C.5    Williams, I.R.6    Gilliland, D.G.7
  • 248
    • 0032924293 scopus 로고    scopus 로고
    • v-src induces cisplatin resistance by increasing the repair of cisplatin-DNA interstrand cross-links in human gallbladder adenocarcinoma cells
    • Masumoto N,Nakano S,Fujishima H,Kohno K,Niho Y.v-src induces cisplatin resistance by increasing the repair of cisplatin-DNA interstrand cross-links in human gallbladder adenocarcinoma cells.Int J Cancer. 1999;80:731-7.
    • (1999) Int J Cancer , vol.80 , pp. 731-737
    • Masumoto, N.1    Nakano, S.2    Fujishima, H.3    Kohno, K.4    Niho, Y.5
  • 249
    • 0028200221 scopus 로고
    • Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells
    • Pietras RJ,Fendly BM,Chazin VR,Pegram MD,Howell SB,Slamon DJ.Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.Oncogene. 1994;9:1829-38.
    • (1994) Oncogene , vol.9 , pp. 1829-1838
    • Pietras, R.J.1    Fendly, B.M.2    Chazin, V.R.3    Pegram, M.D.4    Howell, S.B.5    Slamon, D.J.6
  • 250
  • 251
    • 0031105070 scopus 로고    scopus 로고
    • Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL
    • Sattler M,Salgia R.Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.Cytokine Growth Factor Rev. 1997;8:63-79.
    • (1997) Cytokine Growth Factor Rev , vol.8 , pp. 63-79
    • Sattler, M.1    Salgia, R.2
  • 252
    • 0033603435 scopus 로고    scopus 로고
    • Signaling pathways activated by oncogenic forms of Abl tyrosine kinase
    • Zou X,Calame K.Signaling pathways activated by oncogenic forms of Abl tyrosine kinase.J Biol Chem. 1999;274:18141-4.
    • (1999) J Biol Chem , vol.274 , pp. 18141-18144
    • Zou, X.1    Calame, K.2
  • 253
    • 0031439247 scopus 로고    scopus 로고
    • Cellular functions regulated by Src family kinases
    • Thomas SM,Brugge JS.Cellular functions regulated by Src family kinases.Annu Rev Cell Dev Biol. 1997;13:513-609.
    • (1997) Annu Rev Cell Dev Biol , vol.13 , pp. 513-609
    • Thomas, S.M.1    Brugge, J.S.2
  • 255
    • 33645310982 scopus 로고    scopus 로고
    • ITAM-mediated tonic signalling through pre-BCR and BCR complexes
    • Monroe JG.ITAM-mediated tonic signalling through pre-BCR and BCR complexes.Nat Rev Immunol. 2006;6:283-94.
    • (2006) Nat Rev Immunol , vol.6 , pp. 283-294
    • Monroe, J.G.1
  • 258
    • 0031008896 scopus 로고    scopus 로고
    • ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
    • Morris SW,Naeve C,Mathew P,James PL,Kirstein MN,Cui X,Witte DP.ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK).Oncogene. 1997;14:2175-88.
    • (1997) Oncogene , vol.14 , pp. 2175-2188
    • Morris, S.W.1    Naeve, C.2    Mathew, P.3    James, P.L.4    Kirstein, M.N.5    Cui, X.6    Witte, D.P.7
  • 259
    • 0036278515 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid-mediated apoptosis in hematological malignancies
    • Greenstein S,Ghias K,Krett NL,Rosen ST.Mechanisms of glucocorticoid-mediated apoptosis in hematological malignancies.Clin Cancer Res. 2002;8:1681-94.
    • (2002) Clin Cancer Res , vol.8 , pp. 1681-1694
    • Greenstein, S.1    Ghias, K.2    Krett, N.L.3    Rosen, S.T.4
  • 261
    • 0032619951 scopus 로고    scopus 로고
    • Glucocorticosteroid therapy in childhood acute lymphoblastic leukemia
    • Gaynon PS,Carrel AL.Glucocorticosteroid therapy in childhood acute lymphoblastic leukemia.Adv Exp Med Biol. 1999;457:593-605.
    • (1999) Adv Exp Med Biol , vol.457 , pp. 593-605
    • Gaynon, P.S.1    Carrel, A.L.2
  • 263
    • 0034517924 scopus 로고    scopus 로고
    • Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Munster
    • Schrappe M,Reiter A,Zimmermann M,Harbott J,Ludwig WD,Henze G,Gadner H,Odenwald E,Riehm H.Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Munster.Leukemia. 2000;14:2205-22.
    • (2000) Leukemia , vol.14 , pp. 2205-2222
    • Schrappe, M.1    Reiter, A.2    Zimmermann, M.3    Harbott, J.4    Ludwig, W.D.5    Henze, G.6    Gadner, H.7    Odenwald, E.8    Riehm, H.9
  • 270
    • 42549119526 scopus 로고    scopus 로고
    • Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy
    • Li R,Morris SW.Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy.Med Res Rev. 2008;28:372-412.
    • (2008) Med Res Rev , vol.28 , pp. 372-412
    • Li, R.1    Morris, S.W.2
  • 271
    • 56349118798 scopus 로고    scopus 로고
    • Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis
    • Gu L,Gao J,Li Q,Zhu YP,Jia CS,Fu RY,Chen Y,Liao QK,Ma Z.Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis.Leukemia. 2008;22:2091-6.
    • (2008) Leukemia , vol.22 , pp. 2091-2096
    • Gu, L.1    Gao, J.2    Li, Q.3    Zhu, Y.P.4    Jia, C.S.5    Fu, R.Y.6    Chen, Y.7    Liao, Q.K.8    Ma, Z.9
  • 272
    • 33846951463 scopus 로고    scopus 로고
    • Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf
    • Marzec M,Kasprzycka M,Liu X,Raghunath PN,Wlodarski P,Wasik MA.Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.Oncogene. 2007;26:813-21.
    • (2007) Oncogene , vol.26 , pp. 813-821
    • Marzec, M.1    Kasprzycka, M.2    Liu, X.3    Raghunath, P.N.4    Wlodarski, P.5    Wasik, M.A.6
  • 273
    • 33746118057 scopus 로고    scopus 로고
    • Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma
    • Vega F,Medeiros LJ,Leventaki V,Atwell C,Cho-Vega JH,Tian L,Claret FX,Rassidakis GZ.Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.Cancer Res. 2006;66:6589-97.
    • (2006) Cancer Res , vol.66 , pp. 6589-6597
    • Vega, F.1    Medeiros, L.J.2    Leventaki, V.3    Atwell, C.4    Cho-Vega, J.H.5    Tian, L.6    Claret, F.X.7    Rassidakis, G.Z.8
  • 275
    • 33846006506 scopus 로고    scopus 로고
    • In vitro studies of DNA damage and its repair in cells from NHL patients with different p53 mutant protein status, resistant (p53(+)) and sensitive (p53(-)) to cancer chemotherapy
    • Foroutan B,Ali Ruf A,Jerwood D,Anderson D.In vitro studies of DNA damage and its repair in cells from NHL patients with different p53 mutant protein status, resistant (p53(+)) and sensitive (p53(-)) to cancer chemotherapy.J Pharmacol Toxicol Methods. 2007;55:58-64.
    • (2007) J Pharmacol Toxicol Methods , vol.55 , pp. 58-64
    • Foroutan, B.1    Ali Ruf, A.2    Jerwood, D.3    Anderson, D.4
  • 277
    • 0033955825 scopus 로고    scopus 로고
    • p53 alterations in human leukemia-lymphoma cell lines: in vitroartifact or prerequisite for cell immortalization?
    • Drexler HG,Fombonne S,Matsuo Y,Hu ZB,Hamaguchi H,Uphoff CC.p53 alterations in human leukemia-lymphoma cell lines: in vitroartifact or prerequisite for cell immortalization?.Leukemia. 2000;14:198-206.
    • (2000) Leukemia , vol.14 , pp. 198-206
    • Drexler, H.G.1    Fombonne, S.2    Matsuo, Y.3    Hu, Z.B.4    Hamaguchi, H.5    Uphoff, C.C.6
  • 279
    • 0032901751 scopus 로고    scopus 로고
    • Disrupted p53 function as predictor of treatment failure and poor prognosis in B- and T-cell non-Hodgkin's lymphoma
    • Moller MB,Gerdes AM,Skjodt K,Mortensen LS,Pedersen NT.Disrupted p53 function as predictor of treatment failure and poor prognosis in B- and T-cell non-Hodgkin's lymphoma.Clin Cancer Res. 1999;5:1085-91.
    • (1999) Clin Cancer Res , vol.5 , pp. 1085-1091
    • Moller, M.B.1    Gerdes, A.M.2    Skjodt, K.3    Mortensen, L.S.4    Pedersen, N.T.5
  • 280
    • 0030831742 scopus 로고    scopus 로고
    • Correlation between mutation in p53, p53 expression, cytogenetics, histologic type, and survival in patients with B-cell non-Hodgkin's lymphoma
    • Koduru PR,Raju K,Vadmal V,Menezes G,Shah S,Susin M,Kolitz J,Broome JD.Correlation between mutation in p53, p53 expression, cytogenetics, histologic type, and survival in patients with B-cell non-Hodgkin's lymphoma.Blood. 1997;90:4078-91.
    • (1997) Blood , vol.90 , pp. 4078-4091
    • Koduru, P.R.1    Raju, K.2    Vadmal, V.3    Menezes, G.4    Shah, S.5    Susin, M.6    Kolitz, J.7    Broome, J.D.8
  • 282
    • 2342667387 scopus 로고    scopus 로고
    • The development of proteasome inhibitors as anticancer drugs
    • Adams J.The development of proteasome inhibitors as anticancer drugs.Cancer Cell. 2004;5:417-21.
    • (2004) Cancer Cell , vol.5 , pp. 417-421
    • Adams, J.1
  • 284
    • 41549133200 scopus 로고    scopus 로고
    • Proteasome inhibitors in cancer therapy: lessons from the first decade
    • Orlowski RZ,Kuhn DJ.Proteasome inhibitors in cancer therapy: lessons from the first decade.Clin Cancer Res. 2008;14:1649-57.
    • (2008) Clin Cancer Res , vol.14 , pp. 1649-1657
    • Orlowski, R.Z.1    Kuhn, D.J.2
  • 285
    • 33847410207 scopus 로고    scopus 로고
    • The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells
    • Stapnes C,Doskeland AP,Hatfield K,Ersvaer E,Ryningen A,Lorens JB,Gjertsen BT,Bruserud O.The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells.Br J Haematol. 2007;136:814-28.
    • (2007) Br J Haematol , vol.136 , pp. 814-828
    • Stapnes, C.1    Doskeland, A.P.2    Hatfield, K.3    Ersvaer, E.4    Ryningen, A.5    Lorens, J.B.6    Gjertsen, B.T.7    Bruserud, O.8
  • 286
    • 34047257880 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib acts independently of p53 and induces cell death via apoptosis and mitotic catastrophe in B-cell lymphoma cell lines
    • Strauss SJ,Higginbottom K,Juliger S,Maharaj L,Allen P,Schenkein D,Lister TA,Joel SP.The proteasome inhibitor bortezomib acts independently of p53 and induces cell death via apoptosis and mitotic catastrophe in B-cell lymphoma cell lines.Cancer Res. 2007;67:2783-90.
    • (2007) Cancer Res , vol.67 , pp. 2783-2790
    • Strauss, S.J.1    Higginbottom, K.2    Juliger, S.3    Maharaj, L.4    Allen, P.5    Schenkein, D.6    Lister, T.A.7    Joel, S.P.8
  • 288
    • 33744539521 scopus 로고    scopus 로고
    • Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
    • Obeng EA,Carlson LM,Gutman DM,Harrington WJ,Lee KP,Boise LH.Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells.Blood. 2006;107:4907-16.
    • (2006) Blood , vol.107 , pp. 4907-4916
    • Obeng, E.A.1    Carlson, L.M.2    Gutman, D.M.3    Harrington, W.J.4    Lee, K.P.5    Boise, L.H.6
  • 289
    • 53049083867 scopus 로고    scopus 로고
    • Mechanisms of proteasome inhibitor action and resistance in cancer
    • McConkey DJ,Zhu K.Mechanisms of proteasome inhibitor action and resistance in cancer.Drug Resist Updat. 2008;11:164-79.
    • (2008) Drug Resist Updat , vol.11 , pp. 164-179
    • McConkey, D.J.1    Zhu, K.2
  • 294
    • 0032499199 scopus 로고    scopus 로고
    • A proteolytic system that compensates for loss of proteasome function
    • Glas R,Bogyo M,McMaster JS,Gaczynska M,Ploegh HL.A proteolytic system that compensates for loss of proteasome function.Nature. 1998;392:618-22.
    • (1998) Nature , vol.392 , pp. 618-622
    • Glas, R.1    Bogyo, M.2    McMaster, J.S.3    Gaczynska, M.4    Ploegh, H.L.5
  • 295
    • 0035895299 scopus 로고    scopus 로고
    • Cells adapted to the proteasome inhibitor 4-hydroxy-5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival
    • Princiotta MF,Schubert U,Chen W,Bennink JR,Myung J,Crews CM,Yewdell JW.Cells adapted to the proteasome inhibitor 4-hydroxy-5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival.Proc Natl Acad Sci USA. 2001;98:513-8.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 513-518
    • Princiotta, M.F.1    Schubert, U.2    Chen, W.3    Bennink, J.R.4    Myung, J.5    Crews, C.M.6    Yewdell, J.W.7
  • 296
    • 0035801514 scopus 로고    scopus 로고
    • Lysosomal cysteine proteases: facts and opportunities
    • Turk V,Turk B,Turk D.Lysosomal cysteine proteases: facts and opportunities.EMBO J. 2001;20:4629-33.
    • (2001) EMBO J , vol.20 , pp. 4629-4633
    • Turk, V.1    Turk, B.2    Turk, D.3
  • 297
    • 33646171070 scopus 로고    scopus 로고
    • Stress induction of GRP78/BiP and its role in cancer
    • Li J,Lee AS.Stress induction of GRP78/BiP and its role in cancer.Curr Mol Med. 2006;6:45-54.
    • (2006) Curr Mol Med , vol.6 , pp. 45-54
    • Li, J.1    Lee, A.S.2
  • 298
    • 80054969637 scopus 로고    scopus 로고
    • The expression of the endoplasmic reticulum stress sensor BiP/GRP78 predicts response to chemotherapy and determines the efficacy of proteasome inhibitors in diffuse large B-cell lymphoma
    • Mozos A,Roue G,Lopez-Guillermo A,Jares P,Campo E,Colomer D,Martinez A.The expression of the endoplasmic reticulum stress sensor BiP/GRP78 predicts response to chemotherapy and determines the efficacy of proteasome inhibitors in diffuse large B-cell lymphoma.Am J Pathol. 2011;179:2601-10.
    • (2011) Am J Pathol , vol.179 , pp. 2601-2610
    • Mozos, A.1    Roue, G.2    Lopez-Guillermo, A.3    Jares, P.4    Campo, E.5    Colomer, D.6    Martinez, A.7
  • 299
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M.Epigenetics in cancer.N Engl J Med. 2008;358:1148-59.
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 300
    • 34248631385 scopus 로고    scopus 로고
    • The role of histone deacetylases (HDACs) in human cancer
    • Ropero S,Esteller M.The role of histone deacetylases (HDACs) in human cancer.Mol Oncol. 2007;1:19-25.
    • (2007) Mol Oncol , vol.1 , pp. 19-25
    • Ropero, S.1    Esteller, M.2
  • 301
    • 39749127166 scopus 로고    scopus 로고
    • The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men
    • Yang XJ,Seto E.The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men.Nat Rev Mol Cell Biol. 2008;9:206-18.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 206-218
    • Yang, X.J.1    Seto, E.2
  • 304
    • 0034596309 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells
    • Marks PA,Richon VM,Rifkind RA.Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells.J Natl Cancer Inst. 2000;92:1210-16.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1210-1216
    • Marks, P.A.1    Richon, V.M.2    Rifkind, R.A.3
  • 305
    • 0032868358 scopus 로고    scopus 로고
    • The Ig heavy chain intronic enhancer core region is necessary and sufficient to promote efficient class switch recombination
    • Sakai E,Bottaro A,Alt FW.The Ig heavy chain intronic enhancer core region is necessary and sufficient to promote efficient class switch recombination.Int Immunol. 1999;11:1709-13.
    • (1999) Int Immunol , vol.11 , pp. 1709-1713
    • Sakai, E.1    Bottaro, A.2    Alt, F.W.3
  • 307
    • 0037074010 scopus 로고    scopus 로고
    • Signaling network model of chromatin
    • Schreiber SL,Bernstein BE.Signaling network model of chromatin.Cell. 2002;111:771-8.
    • (2002) Cell , vol.111 , pp. 771-778
    • Schreiber, S.L.1    Bernstein, B.E.2
  • 310
    • 14044276343 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas
    • Duan H,Heckman CA,Boxer LM.Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas.Mol Cell Biol. 2005;25:1608-19.
    • (2005) Mol Cell Biol , vol.25 , pp. 1608-1619
    • Duan, H.1    Heckman, C.A.2    Boxer, L.M.3
  • 312
    • 77953937449 scopus 로고    scopus 로고
    • The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo
    • Dasmahapatra G,Lembersky D,Kramer L,Fisher RI,Friedberg J,Dent P,Grant S.The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo.Blood. 2010;115:4478-87.
    • (2010) Blood , vol.115 , pp. 4478-4487
    • Dasmahapatra, G.1    Lembersky, D.2    Kramer, L.3    Fisher, R.I.4    Friedberg, J.5    Dent, P.6    Grant, S.7
  • 313
    • 77958009878 scopus 로고    scopus 로고
    • HDAC inhibitors augment cytotoxic activity of rituximab by upregulating CD20 expression on lymphoma cells
    • Shimizu R,Kikuchi J,Wada T,Ozawa K,Kano Y,Furukawa Y.HDAC inhibitors augment cytotoxic activity of rituximab by upregulating CD20 expression on lymphoma cells.Leukemia. 2010;24:1760-8.
    • (2010) Leukemia , vol.24 , pp. 1760-1768
    • Shimizu, R.1    Kikuchi, J.2    Wada, T.3    Ozawa, K.4    Kano, Y.5    Furukawa, Y.6
  • 316
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov Y,Peinado MA,Malkhosyan S,Shibata D,Perucho M.Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis.Nature. 1993;363:558-61.
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3    Shibata, D.4    Perucho, M.5
  • 318
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Thibodeau SN,Bren G,Schaid D.Microsatellite instability in cancer of the proximal colon.Science. 1993;260:816-9.
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.N.1    Bren, G.2    Schaid, D.3
  • 321
    • 34548841964 scopus 로고    scopus 로고
    • Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia
    • Williams RT,den Besten W,Sherr CJ.Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia.Genes Dev. 2007;21:2283-7.
    • (2007) Genes Dev , vol.21 , pp. 2283-2287
    • Williams, R.T.1    den Besten, W.2    Sherr, C.J.3
  • 324
    • 52049103847 scopus 로고    scopus 로고
    • The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance
    • Meads MB,Hazlehurst LA,Dalton WS.The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance.Clin Cancer Res. 2008;14:2519-26.
    • (2008) Clin Cancer Res , vol.14 , pp. 2519-2526
    • Meads, M.B.1    Hazlehurst, L.A.2    Dalton, W.S.3
  • 326
    • 0031004077 scopus 로고    scopus 로고
    • Germinal center-derived signals act with Bcl-2 to decrease apoptosis and increase clonogenicity of drug-treated human B lymphoma cells
    • Walker A,Taylor ST,Hickman JA,Dive C.Germinal center-derived signals act with Bcl-2 to decrease apoptosis and increase clonogenicity of drug-treated human B lymphoma cells.Cancer Res. 1997;57:1939-45.
    • (1997) Cancer Res , vol.57 , pp. 1939-1945
    • Walker, A.1    Taylor, S.T.2    Hickman, J.A.3    Dive, C.4
  • 327
    • 0032894509 scopus 로고    scopus 로고
    • Survival signals within the tumour microenvironment suppress drug-induced apoptosis: lessons learned from B lymphomas
    • Taylor ST,Hickman JA,Dive C.Survival signals within the tumour microenvironment suppress drug-induced apoptosis: lessons learned from B lymphomas.Endocr Relat Cancer. 1999;6:21-3.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 21-23
    • Taylor, S.T.1    Hickman, J.A.2    Dive, C.3
  • 328
    • 0032915632 scopus 로고    scopus 로고
    • TALL-1 is a novel member of the TNF family that is down-regulated by mitogens
    • Shu HB,Hu WH,Johnson H.TALL-1 is a novel member of the TNF family that is down-regulated by mitogens.J Leukoc Biol. 1999;65:680-3.
    • (1999) J Leukoc Biol , vol.65 , pp. 680-683
    • Shu, H.B.1    Hu, W.H.2    Johnson, H.3
  • 329
    • 0027243576 scopus 로고
    • p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction
    • Mercurio F,DiDonato JA,Rosette C,Karin M.p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction.Genes Dev. 1993;7:705-18.
    • (1993) Genes Dev , vol.7 , pp. 705-718
    • Mercurio, F.1    DiDonato, J.A.2    Rosette, C.3    Karin, M.4
  • 330
    • 0027472317 scopus 로고
    • The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are I kappa B molecules and control nuclear translocation of NF-kappa B
    • Naumann M,Wulczyn FG,Scheidereit C.The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are I kappa B molecules and control nuclear translocation of NF-kappa B.EMBO J. 1993;12:213-22.
    • (1993) EMBO J , vol.12 , pp. 213-222
    • Naumann, M.1    Wulczyn, F.G.2    Scheidereit, C.3
  • 331
    • 58249102301 scopus 로고    scopus 로고
    • Lymphoma cell adhesion-induced expression of B cell-activating factor of the TNF family in bone marrow stromal cells protects non-Hodgkin's B lymphoma cells from apoptosis
    • Lwin T,Crespo LA,Wu A,Dessureault S,Shu HB,Moscinski LC,Sotomayor E,Dalton WS,Tao J.Lymphoma cell adhesion-induced expression of B cell-activating factor of the TNF family in bone marrow stromal cells protects non-Hodgkin's B lymphoma cells from apoptosis.Leukemia. 2009;23:170-7.
    • (2009) Leukemia , vol.23 , pp. 170-177
    • Lwin, T.1    Crespo, L.A.2    Wu, A.3    Dessureault, S.4    Shu, H.B.5    Moscinski, L.C.6    Sotomayor, E.7    Dalton, W.S.8    Tao, J.9
  • 332
    • 0036141462 scopus 로고    scopus 로고
    • BLyS and BLyS receptor expression in non-Hodgkin's lymphoma
    • Briones J,Timmerman JM,Hilbert DM,Levy R.BLyS and BLyS receptor expression in non-Hodgkin's lymphoma.Exp Hematol. 2002;30:135-41.
    • (2002) Exp Hematol , vol.30 , pp. 135-141
    • Briones, J.1    Timmerman, J.M.2    Hilbert, D.M.3    Levy, R.4
  • 333
    • 0027444652 scopus 로고
    • The International Non-Hodgkin's Lymphoma Prognostic Factors Project
    • The International Non-Hodgkin's Lymphoma Prognostic Factors Project.N Engl J Med. 1993;329:987-94.
    • (1993) N Engl J Med , vol.329 , pp. 987-994
  • 334
    • 0025880971 scopus 로고
    • Drug-target interactions: only the first step in the commitment to a programmed cell death?
    • Dive C,Hickman JA.Drug-target interactions: only the first step in the commitment to a programmed cell death?.Br J Cancer. 1991;64:192-6.
    • (1991) Br J Cancer , vol.64 , pp. 192-196
    • Dive, C.1    Hickman, J.A.2
  • 335
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff MC.Social controls on cell survival and cell death.Nature. 1992;356:397-400.
    • (1992) Nature , vol.356 , pp. 397-400
    • Raff, M.C.1
  • 336
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the Bcl-2 family
    • Reed JC.Double identity for proteins of the Bcl-2 family.Nature. 1997;387:773-6.
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 337
    • 0034606657 scopus 로고    scopus 로고
    • Epigenetic determinants of resistance to etoposide regulation of Bcl-X(L) and Bax by tumor microenvironmental factors
    • Taylor ST,Hickman JA,Dive C.Epigenetic determinants of resistance to etoposide regulation of Bcl-X(L) and Bax by tumor microenvironmental factors.J Natl Cancer Inst. 2000;92:18-23.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 18-23
    • Taylor, S.T.1    Hickman, J.A.2    Dive, C.3
  • 338
    • 0142250392 scopus 로고    scopus 로고
    • Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence
    • Trikha M,Corringham R,Klein B,Rossi JF.Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence.Clin Cancer Res. 2003;9:4653-65.
    • (2003) Clin Cancer Res , vol.9 , pp. 4653-4665
    • Trikha, M.1    Corringham, R.2    Klein, B.3    Rossi, J.F.4
  • 339
    • 77958501473 scopus 로고    scopus 로고
    • DNA damage-mediated induction of a chemoresistant niche
    • Gilbert LA,Hemann MT.DNA damage-mediated induction of a chemoresistant niche.Cell. 2010;143:355-66.
    • (2010) Cell , vol.143 , pp. 355-366
    • Gilbert, L.A.1    Hemann, M.T.2
  • 341
    • 0033485625 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells
    • Burger JA,Burger M,Kipps TJ.Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells.Blood. 1999;94:3658-67.
    • (1999) Blood , vol.94 , pp. 3658-3667
    • Burger, J.A.1    Burger, M.2    Kipps, T.J.3
  • 342
    • 36148930616 scopus 로고    scopus 로고
    • Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia
    • Burkle A,Niedermeier M,Schmitt-Graff A,Wierda WG,Keating MJ,Burger JA.Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia.Blood. 2007;110:3316-25.
    • (2007) Blood , vol.110 , pp. 3316-3325
    • Burkle, A.1    Niedermeier, M.2    Schmitt-Graff, A.3    Wierda, W.G.4    Keating, M.J.5    Burger, J.A.6
  • 344
    • 0036119210 scopus 로고    scopus 로고
    • Chemokine receptors and stromal cells in the homing and homeostasis of chronic lymphocytic leukemia B cells
    • Burger JA,Kipps TJ.Chemokine receptors and stromal cells in the homing and homeostasis of chronic lymphocytic leukemia B cells.Leuk Lymphoma. 2002;43:461-6.
    • (2002) Leuk Lymphoma , vol.43 , pp. 461-466
    • Burger, J.A.1    Kipps, T.J.2
  • 347
    • 0037034880 scopus 로고    scopus 로고
    • Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position
    • Reif K,Ekland EH,Ohl L,Nakano H,Lipp M,Forster R,Cyster JG.Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position.Nature. 2002;416:94-9.
    • (2002) Nature , vol.416 , pp. 94-99
    • Reif, K.1    Ekland, E.H.2    Ohl, L.3    Nakano, H.4    Lipp, M.5    Forster, R.6    Cyster, J.G.7
  • 348
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm
    • Springer TA.Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm.Cell. 1994;76:301-14.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 351
    • 24744438473 scopus 로고    scopus 로고
    • Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL)
    • Farinha P,Masoudi H,Skinnider BF,Shumansky K,Spinelli JJ,Gill K,Klasa R,Voss N,Connors JM,Gascoyne RD.Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL).Blood. 2005;106:2169-74.
    • (2005) Blood , vol.106 , pp. 2169-2174
    • Farinha, P.1    Masoudi, H.2    Skinnider, B.F.3    Shumansky, K.4    Spinelli, J.J.5    Gill, K.6    Klasa, R.7    Voss, N.8    Connors, J.M.9    Gascoyne, R.D.10
  • 352
    • 84862260770 scopus 로고    scopus 로고
    • A rare fraction of drug-resistant follicular lymphoma cancer stem cells interacts with follicular dendritic cells to maintain tumourigenic potential
    • Lee CG,Das B,Lin TL,Grimes C,Zhang X,Lavezzi T,Huang L,Cole J,Yau L,Li L.A rare fraction of drug-resistant follicular lymphoma cancer stem cells interacts with follicular dendritic cells to maintain tumourigenic potential.Br J Haematol. 2012;158:79-90.
    • (2012) Br J Haematol , vol.158 , pp. 79-90
    • Lee, C.G.1    Das, B.2    Lin, T.L.3    Grimes, C.4    Zhang, X.5    Lavezzi, T.6    Huang, L.7    Cole, J.8    Yau, L.9    Li, L.10
  • 356
    • 46749153415 scopus 로고    scopus 로고
    • Sphingosine kinase 1 protein and mRNA are overexpressed in non-Hodgkin lymphomas and are attractive targets for novel pharmacological interventions
    • Bayerl MG,Bruggeman RD,Conroy EJ,Hengst JA,King TS,Jimenez M,Claxton DF,Yun JK.Sphingosine kinase 1 protein and mRNA are overexpressed in non-Hodgkin lymphomas and are attractive targets for novel pharmacological interventions.Leuk Lymphoma. 2008;49:948-54.
    • (2008) Leuk Lymphoma , vol.49 , pp. 948-954
    • Bayerl, M.G.1    Bruggeman, R.D.2    Conroy, E.J.3    Hengst, J.A.4    King, T.S.5    Jimenez, M.6    Claxton, D.F.7    Yun, J.K.8
  • 357
    • 79953100959 scopus 로고    scopus 로고
    • Inhibition of geranylgeranylation mediates sensitivity to CHOP-induced cell death of DLBCL cell lines
    • Ageberg M,Rydstrom K,Linden O,Linderoth J,Jerkeman M,Drott K.Inhibition of geranylgeranylation mediates sensitivity to CHOP-induced cell death of DLBCL cell lines.Exp Cell Res. 2011;317:1179-91.
    • (2011) Exp Cell Res , vol.317 , pp. 1179-1191
    • Ageberg, M.1    Rydstrom, K.2    Linden, O.3    Linderoth, J.4    Jerkeman, M.5    Drott, K.6
  • 358
    • 0030860083 scopus 로고    scopus 로고
    • The diversity of Rab proteins in vesicle transport
    • Novick P,Zerial M.The diversity of Rab proteins in vesicle transport.Curr Opin Cell Biol. 1997;9:496-504.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 496-504
    • Novick, P.1    Zerial, M.2
  • 359
    • 33646777423 scopus 로고    scopus 로고
    • Thematic review series: lipid posttranslational modifications. CAAX modification and membrane targeting of Ras
    • Wright LP,Philips MR.Thematic review series: lipid posttranslational modifications. CAAX modification and membrane targeting of Ras.J Lipid Res. 2006;47:883-91.
    • (2006) J Lipid Res , vol.47 , pp. 883-891
    • Wright, L.P.1    Philips, M.R.2
  • 360
  • 361
    • 0030947983 scopus 로고    scopus 로고
    • Evaluation of continuous-infusion gallium nitrate and hydroxyurea in combination for the treatment of refractory non-Hodgkin's lymphoma
    • Chitambar CR,Zahir SA,Ritch PS,Anderson T.Evaluation of continuous-infusion gallium nitrate and hydroxyurea in combination for the treatment of refractory non-Hodgkin's lymphoma.Am J Clin Oncol. 1997;20:173-8.
    • (1997) Am J Clin Oncol , vol.20 , pp. 173-178
    • Chitambar, C.R.1    Zahir, S.A.2    Ritch, P.S.3    Anderson, T.4
  • 362
    • 0022547119 scopus 로고
    • Phase II evaluation of bolus gallium nitrate in lymphoproliferative disorders: a Southeastern Cancer Study Group trial
    • Keller J,Bartolucci A,Carpenter JT,Feagler J.Phase II evaluation of bolus gallium nitrate in lymphoproliferative disorders: a Southeastern Cancer Study Group trial.Cancer Treat Rep. 1986;70:1221-3.
    • (1986) Cancer Treat Rep , vol.70 , pp. 1221-1223
    • Keller, J.1    Bartolucci, A.2    Carpenter, J.T.3    Feagler, J.4
  • 363
    • 0038147469 scopus 로고    scopus 로고
    • Gallium nitrate in the treatment of lymphoma
    • Straus DJ.Gallium nitrate in the treatment of lymphoma.Semin Oncol. 2003;30:25-33.
    • (2003) Semin Oncol , vol.30 , pp. 25-33
    • Straus, D.J.1
  • 364
    • 0020561470 scopus 로고
    • Treatment of patients with advanced malignant lymphoma using gallium nitrate administered as a seven-day continuous infusion
    • Warrell RP,Coonley CJ,Straus DJ,Young CW.Treatment of patients with advanced malignant lymphoma using gallium nitrate administered as a seven-day continuous infusion.Cancer. 1983;51:1982-7.
    • (1983) Cancer , vol.51 , pp. 1982-1987
    • Warrell, R.P.1    Coonley, C.J.2    Straus, D.J.3    Young, C.W.4
  • 365
    • 0020592438 scopus 로고
    • Gallium nitrate in malignant lymphoma: a Southwest Oncology Group study
    • Weick JK,Stephens RL,Baker LH,Jones SE.Gallium nitrate in malignant lymphoma: a Southwest Oncology Group study.Cancer Treat Rep. 1983;67:823-5.
    • (1983) Cancer Treat Rep , vol.67 , pp. 823-825
    • Weick, J.K.1    Stephens, R.L.2    Baker, L.H.3    Jones, S.E.4
  • 366
    • 0023262160 scopus 로고
    • Uptake of gallium-67 by human leukemic cells: demonstration of transferrin receptor-dependent and transferrin-independent mechanisms
    • Chitambar CR,Zivkovic Z.Uptake of gallium-67 by human leukemic cells: demonstration of transferrin receptor-dependent and transferrin-independent mechanisms.Cancer Res. 1987;47:3929-34.
    • (1987) Cancer Res , vol.47 , pp. 3929-3934
    • Chitambar, C.R.1    Zivkovic, Z.2
  • 367
    • 0024388259 scopus 로고
    • An epitope of the transferrin receptor is exposed on the cell surface of high-grade but not low-grade human lymphomas
    • Esserman L,Takahashi S,Rojas V,Warnke R,Levy R.An epitope of the transferrin receptor is exposed on the cell surface of high-grade but not low-grade human lymphomas.Blood. 1989;74:2718-29.
    • (1989) Blood , vol.74 , pp. 2718-2729
    • Esserman, L.1    Takahashi, S.2    Rojas, V.3    Warnke, R.4    Levy, R.5
  • 368
    • 0020685104 scopus 로고
    • Correlation of transferrin receptor expression with histological class and outcome in non-Hodgkin lymphoma
    • Habeshaw JA,Lister TA,Stansfeld AG,Greaves MF.Correlation of transferrin receptor expression with histological class and outcome in non-Hodgkin lymphoma.Lancet. 1983;1:498-501.
    • (1983) Lancet , vol.1 , pp. 498-501
    • Habeshaw, J.A.1    Lister, T.A.2    Stansfeld, A.G.3    Greaves, M.F.4
  • 369
    • 0021107162 scopus 로고
    • Thermodynamic binding constants for gallium transferrin
    • Harris WR,Pecoraro VL.Thermodynamic binding constants for gallium transferrin.Biochemistry. 1983;22:292-9.
    • (1983) Biochemistry , vol.22 , pp. 292-299
    • Harris, W.R.1    Pecoraro, V.L.2
  • 370
    • 0034293535 scopus 로고    scopus 로고
    • Correlation of flow cytometric parameters and transferrin receptors with gallium-67 scintigraphic images in lymphoma patients
    • Kiratli PO,Canpinar H,Ruacan S,Kansu E.Correlation of flow cytometric parameters and transferrin receptors with gallium-67 scintigraphic images in lymphoma patients.Nucl Med Commun. 2000;21:925-31.
    • (2000) Nucl Med Commun , vol.21 , pp. 925-931
    • Kiratli, P.O.1    Canpinar, H.2    Ruacan, S.3    Kansu, E.4
  • 372
    • 33847409311 scopus 로고    scopus 로고
    • Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate
    • Yang M,Kroft SH,Chitambar CR.Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate.Mol Cancer Ther. 2007;6:633-43.
    • (2007) Mol Cancer Ther , vol.6 , pp. 633-643
    • Yang, M.1    Kroft, S.H.2    Chitambar, C.R.3
  • 373
    • 14944362858 scopus 로고    scopus 로고
    • Regulation of plasma-cell development
    • Shapiro-Shelef M,Calame K.Regulation of plasma-cell development.Nat Rev Immunol. 2005;5:230-42.
    • (2005) Nat Rev Immunol , vol.5 , pp. 230-242
    • Shapiro-Shelef, M.1    Calame, K.2
  • 374
    • 28544444025 scopus 로고    scopus 로고
    • Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow
    • Shapiro-Shelef M,Lin KI,Savitsky D,Liao J,Calame K.Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow.J Exp Med. 2005;202:1471-6.
    • (2005) J Exp Med , vol.202 , pp. 1471-1476
    • Shapiro-Shelef, M.1    Lin, K.I.2    Savitsky, D.3    Liao, J.4    Calame, K.5
  • 375
    • 0037443482 scopus 로고    scopus 로고
    • Identification of a functionally impaired positive regulatory domain I binding factor 1 transcription repressor in myeloma cell lines
    • Gyory I,Fejer G,Ghosh N,Seto E,Wright KL.Identification of a functionally impaired positive regulatory domain I binding factor 1 transcription repressor in myeloma cell lines.J Immunol. 2003;170:3125-33.
    • (2003) J Immunol , vol.170 , pp. 3125-3133
    • Gyory, I.1    Fejer, G.2    Ghosh, N.3    Seto, E.4    Wright, K.L.5
  • 382
    • 4444225475 scopus 로고    scopus 로고
    • Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity
    • Hess DA,Meyerrose TE,Wirthlin L,Craft TP,Herrbrich PE,Creer MH,Nolta JA.Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity.Blood. 2004;104:1648-55.
    • (2004) Blood , vol.104 , pp. 1648-1655
    • Hess, D.A.1    Meyerrose, T.E.2    Wirthlin, L.3    Craft, T.P.4    Herrbrich, P.E.5    Creer, M.H.6    Nolta, J.A.7
  • 385
    • 0021722034 scopus 로고    scopus 로고
    • Role of aldehyde dehydrogenase in cyclophosphamide-resistant L1210 leukemia
    • Hilton J.Role of aldehyde dehydrogenase in cyclophosphamide-resistant L1210 leukemia.Cancer Res. 2004;44:5156-60.
    • (2004) Cancer Res , vol.44 , pp. 5156-5160
    • Hilton, J.1
  • 386
    • 0025707866 scopus 로고    scopus 로고
    • Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells
    • Kastan MB,Schlaffer E,Russo JE,Colvin OM,Civin CI,Hilton J.Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells.Blood. 75:1947-50.
    • Blood , vol.75 , pp. 1947-1950
    • Kastan, M.B.1    Schlaffer, E.2    Russo, J.E.3    Colvin, O.M.4    Civin, C.I.5    Hilton, J.6
  • 387
    • 0022220140 scopus 로고
    • Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorines
    • Kohn FR,Sladek NE.Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorines.Biochem Pharmacol. 1985;34:3465-71.
    • (1985) Biochem Pharmacol , vol.34 , pp. 3465-3471
    • Kohn, F.R.1    Sladek, N.E.2
  • 388
    • 0030024868 scopus 로고    scopus 로고
    • Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer
    • Magni M,Shammah S,Schiro R,Mellado W,Dalla-Favera R,Gianni AM.Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer.Blood. 1996;87:1097-103.
    • (1996) Blood , vol.87 , pp. 1097-1103
    • Magni, M.1    Shammah, S.2    Schiro, R.3    Mellado, W.4    Dalla-Favera, R.5    Gianni, A.M.6
  • 389
    • 0023952342 scopus 로고
    • Characterization of cytosolic aldehyde dehydrogenase from cyclophosphamide resistant L1210 cells
    • Russo JE,Hilton J.Characterization of cytosolic aldehyde dehydrogenase from cyclophosphamide resistant L1210 cells.Cancer Res. 1988;48:2963-8.
    • (1988) Cancer Res , vol.48 , pp. 2963-2968
    • Russo, J.E.1    Hilton, J.2
  • 392
    • 33751172982 scopus 로고    scopus 로고
    • Aggresome induction by proteasome inhibitor bortezomib and alpha-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells
    • Catley L,Weisberg E,Kiziltepe T,Tai YT,Hideshima T,Neri P,Tassone P,Atadja P,Chauhan D,Munshi NC,Anderson KC.Aggresome induction by proteasome inhibitor bortezomib and alpha-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells.Blood. 2006;108:3441-9.
    • (2006) Blood , vol.108 , pp. 3441-3449
    • Catley, L.1    Weisberg, E.2    Kiziltepe, T.3    Tai, Y.T.4    Hideshima, T.5    Neri, P.6    Tassone, P.7    Atadja, P.8    Chauhan, D.9    Munshi, N.C.10    Anderson, K.C.11
  • 393
    • 38949105902 scopus 로고    scopus 로고
    • Interactions between bortezomib and romidepsin and belinostat in chronic lymphocytic leukemia cells
    • Dai Y,Chen S,Kramer LB,Funk VL,Dent P,Grant S.Interactions between bortezomib and romidepsin and belinostat in chronic lymphocytic leukemia cells.Clin Cancer Res. 2008;14:549-58.
    • (2008) Clin Cancer Res , vol.14 , pp. 549-558
    • Dai, Y.1    Chen, S.2    Kramer, L.B.3    Funk, V.L.4    Dent, P.5    Grant, S.6
  • 394
    • 79960432161 scopus 로고    scopus 로고
    • Distinct apoptotic signaling characteristics of the anti-CD40 monoclonal antibody dacetuzumab and rituximab produce enhanced antitumor activity in non-Hodgkin lymphoma
    • Lewis TS,McCormick RS,Emmerton K,Lau JT,Yu SF,McEarchern JA,Grewal IS,Law CL.Distinct apoptotic signaling characteristics of the anti-CD40 monoclonal antibody dacetuzumab and rituximab produce enhanced antitumor activity in non-Hodgkin lymphoma.Clin Cancer Res. 2011;17:4672-81.
    • (2011) Clin Cancer Res , vol.17 , pp. 4672-4681
    • Lewis, T.S.1    McCormick, R.S.2    Emmerton, K.3    Lau, J.T.4    Yu, S.F.5    McEarchern, J.A.6    Grewal, I.S.7    Law, C.L.8
  • 395
    • 84862701321 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib targets cell cycle and apoptosis and acts synergistically in a sequence-dependent way with chemotherapeutic agents in mantle cell lymphoma
    • Hutter G,Rieken M,Pastore A,Weigert O,Zimmermann Y,Weinkauf M,Hiddemann W,Dreyling M.The proteasome inhibitor bortezomib targets cell cycle and apoptosis and acts synergistically in a sequence-dependent way with chemotherapeutic agents in mantle cell lymphoma.Ann Hematol. 2012;91:847-56.
    • (2012) Ann Hematol , vol.91 , pp. 847-856
    • Hutter, G.1    Rieken, M.2    Pastore, A.3    Weigert, O.4    Zimmermann, Y.5    Weinkauf, M.6    Hiddemann, W.7    Dreyling, M.8
  • 397
    • 68549135304 scopus 로고    scopus 로고
    • Phospho-p70S6K and cdc2/cdk1 as therapeutic targets for diffuse large B-cell lymphoma
    • Zhao XF,Gartenhaus RB.Phospho-p70S6K and cdc2/cdk1 as therapeutic targets for diffuse large B-cell lymphoma.Expert Opinion Ther Targets. 2009;13:1085-93.
    • (2009) Expert Opinion Ther Targets , vol.13 , pp. 1085-1093
    • Zhao, X.F.1    Gartenhaus, R.B.2
  • 398
    • 34547603628 scopus 로고    scopus 로고
    • BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents
    • Deng J,Carlson N,Takeyama K,Dal Cin P,Shipp M,Letai A.BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents.Cancer Cell. 2007;12:171-85.
    • (2007) Cancer Cell , vol.12 , pp. 171-185
    • Deng, J.1    Carlson, N.2    Takeyama, K.3    Dal Cin, P.4    Shipp, M.5    Letai, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.