-
1
-
-
0021934042
-
Cloning the chromosomal breakpoint of t(14;18) human lymphomas: Clustering around JH on chromosome 14 and near a transcriptional unit on 18
-
Bakhshi A., Jensen J.P., Goldman P., Wright J.J., McBride O.W., Epstein A.L., and Korsmeyer S.J. Cloning the chromosomal breakpoint of t(14;18) human lymphomas: Clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell 41 (1985) 899-906
-
(1985)
Cell
, vol.41
, pp. 899-906
-
-
Bakhshi, A.1
Jensen, J.P.2
Goldman, P.3
Wright, J.J.4
McBride, O.W.5
Epstein, A.L.6
Korsmeyer, S.J.7
-
2
-
-
9744244990
-
The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA
-
Cartron P.F., Gallenne T., Bougras G., Gautier F., Manero F., Vusio P., Meflah K., Vallette F.M., and Juin P. The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA. Mol. Cell 16 (2004) 807-818
-
(2004)
Mol. Cell
, vol.16
, pp. 807-818
-
-
Cartron, P.F.1
Gallenne, T.2
Bougras, G.3
Gautier, F.4
Manero, F.5
Vusio, P.6
Meflah, K.7
Vallette, F.M.8
Juin, P.9
-
3
-
-
33646354381
-
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
-
Certo M., Moore Vdel G., Nishino M., Wei G., Korsmeyer S., Armstrong S.A., and Letai A. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. Cancer Cell 9 (2006) 351-365
-
(2006)
Cancer Cell
, vol.9
, pp. 351-365
-
-
Certo, M.1
Moore Vdel, G.2
Nishino, M.3
Wei, G.4
Korsmeyer, S.5
Armstrong, S.A.6
Letai, A.7
-
4
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L., Willis S.N., Wei A., Smith B.J., Fletcher J.I., Hinds M.G., Colman P.M., Day C.L., Adams J.M., and Huang D.C. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol. Cell 17 (2005) 393-403
-
(2005)
Mol. Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
Smith, B.J.4
Fletcher, J.I.5
Hinds, M.G.6
Colman, P.M.7
Day, C.L.8
Adams, J.M.9
Huang, D.C.10
-
5
-
-
0030026865
-
Bax-independent inhibition of apoptosis by Bcl-XL
-
Cheng E.H., Levine B., Boise L.H., Thompson C.B., and Hardwick J.M. Bax-independent inhibition of apoptosis by Bcl-XL. Nature 379 (1996) 554-556
-
(1996)
Nature
, vol.379
, pp. 554-556
-
-
Cheng, E.H.1
Levine, B.2
Boise, L.H.3
Thompson, C.B.4
Hardwick, J.M.5
-
6
-
-
0034786019
-
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
-
Cheng E.H., Wei M.C., Weiler S., Flavell R.A., Mak T.W., Lindsten T., and Korsmeyer S.J. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol. Cell 8 (2001) 705-711
-
(2001)
Mol. Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.C.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
Korsmeyer, S.J.7
-
7
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk J.E., Kuwana T., Bouchier-Hayes L., Droin N.M., Newmeyer D.D., Schuler M., and Green D.R. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303 (2004) 1010-1014
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
8
-
-
25444520537
-
miR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A., Calin G.A., Fabbri M., Iorio M.V., Ferracin M., Shimizu M., Wojcik S.E., Aqeilan R.I., Zupo S., Dono M., et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl. Acad. Sci. USA 102 (2005) 13944-13949
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
Iorio, M.V.4
Ferracin, M.5
Shimizu, M.6
Wojcik, S.E.7
Aqeilan, R.I.8
Zupo, S.9
Dono, M.10
-
9
-
-
0345055662
-
Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18
-
Cleary M.L., and Sklar J. Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. Proc. Natl. Acad. Sci. USA 82 (1985) 7439-7443
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 7439-7443
-
-
Cleary, M.L.1
Sklar, J.2
-
10
-
-
0036716281
-
The Bcl2 family: Regulators of the cellular life-or-death switch
-
Cory S., and Adams J.M. The Bcl2 family: Regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2 (2002) 647-656
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
11
-
-
0842281645
-
Cell death: Critical control points
-
Danial N.N., and Korsmeyer S.J. Cell death: Critical control points. Cell 116 (2004) 205-219
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
12
-
-
0031032294
-
Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
-
Decaudin D., Geley S., Hirsch T., Castedo M., Marchetti P., Macho A., Kofler R., and Kroemer G. Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res. 57 (1997) 62-67
-
(1997)
Cancer Res.
, vol.57
, pp. 62-67
-
-
Decaudin, D.1
Geley, S.2
Hirsch, T.3
Castedo, M.4
Marchetti, P.5
Macho, A.6
Kofler, R.7
Kroemer, G.8
-
13
-
-
33845994359
-
Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
-
Del Gaizo Moore V., Brown J.R., Certo M., Love T.M., Novina C.D., and Letai A. Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737. J. Clin. Invest. 117 (2007) 112-121
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 112-121
-
-
Del Gaizo Moore, V.1
Brown, J.R.2
Certo, M.3
Love, T.M.4
Novina, C.D.5
Letai, A.6
-
14
-
-
0033535350
-
Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
-
Desagher S., Osen-Sand A., Nichols A., Eskes R., Montessuit S., Lauper S., Maundrell K., Antonsson B., and Martinou J.C. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J. Cell Biol. 144 (1999) 891-901
-
(1999)
J. Cell Biol.
, vol.144
, pp. 891-901
-
-
Desagher, S.1
Osen-Sand, A.2
Nichols, A.3
Eskes, R.4
Montessuit, S.5
Lauper, S.6
Maundrell, K.7
Antonsson, B.8
Martinou, J.C.9
-
15
-
-
9244257908
-
An Mll-dependent Hox program drives hematopoietic progenitor expansion
-
Ernst P., Mabon M., Davidson A.J., Zon L.I., and Korsmeyer S.J. An Mll-dependent Hox program drives hematopoietic progenitor expansion. Curr. Biol. 14 (2004) 2063-2069
-
(2004)
Curr. Biol.
, vol.14
, pp. 2063-2069
-
-
Ernst, P.1
Mabon, M.2
Davidson, A.J.3
Zon, L.I.4
Korsmeyer, S.J.5
-
16
-
-
0030985194
-
Prognostic significance of Bcl-2 protein expression and Bcl-2 gene rearrangement in diffuse aggressive non-Hodgkin's lymphoma
-
Gascoyne R.D., Adomat S.A., Krajewski S., Krajewska M., Horsman D.E., Tolcher A.W., O'Reilly S.E., Hoskins P., Coldman A.J., Reed J.C., and Connors J.M. Prognostic significance of Bcl-2 protein expression and Bcl-2 gene rearrangement in diffuse aggressive non-Hodgkin's lymphoma. Blood 90 (1997) 244-251
-
(1997)
Blood
, vol.90
, pp. 244-251
-
-
Gascoyne, R.D.1
Adomat, S.A.2
Krajewski, S.3
Krajewska, M.4
Horsman, D.E.5
Tolcher, A.W.6
O'Reilly, S.E.7
Hoskins, P.8
Coldman, A.J.9
Reed, J.C.10
Connors, J.M.11
-
17
-
-
0036463405
-
A matter of life and death
-
Green D.R., and Evan G.I. A matter of life and death. Cancer Cell 1 (2002) 19-30
-
(2002)
Cancer Cell
, vol.1
, pp. 19-30
-
-
Green, D.R.1
Evan, G.I.2
-
18
-
-
3442886811
-
The pathophysiology of mitochondrial cell death
-
Green D.R., and Kroemer G. The pathophysiology of mitochondrial cell death. Science 305 (2004) 626-629
-
(2004)
Science
, vol.305
, pp. 626-629
-
-
Green, D.R.1
Kroemer, G.2
-
19
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A., McDonnell J.M., and Korsmeyer S.J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13 (1999) 1899-1911
-
(1999)
Genes Dev.
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
20
-
-
0036561908
-
Modelling the molecular circuitry of cancer
-
Hahn W.C., and Weinberg R.A. Modelling the molecular circuitry of cancer. Nat. Rev. Cancer 2 (2002) 331-341
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 331-341
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
21
-
-
0031007644
-
Nonionic detergents induce dimerization among members of the Bcl-2 family
-
Hsu Y.T., and Youle R.J. Nonionic detergents induce dimerization among members of the Bcl-2 family. J. Biol. Chem. 272 (1997) 13829-13834
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13829-13834
-
-
Hsu, Y.T.1
Youle, R.J.2
-
22
-
-
0030963602
-
Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis
-
Hsu Y.T., Wolter K.G., and Youle R.J. Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. Proc. Natl. Acad. Sci. USA 94 (1997) 3668-3672
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3668-3672
-
-
Hsu, Y.T.1
Wolter, K.G.2
Youle, R.J.3
-
23
-
-
0033635733
-
BH3-only proteins-Essential initiators of apoptotic cell death
-
Huang D.C., and Strasser A. BH3-only proteins-Essential initiators of apoptotic cell death. Cell 103 (2000) 839-842
-
(2000)
Cell
, vol.103
, pp. 839-842
-
-
Huang, D.C.1
Strasser, A.2
-
24
-
-
33644896809
-
BCL2 expression is a prognostic marker for the activated B-cell-like type of diffuse large B-cell lymphoma
-
Iqbal J., Neppalli V.T., Wright G., Dave B.J., Horsman D.E., Rosenwald A., Lynch J., Hans C.P., Weisenburger D.D., Greiner T.C., et al. BCL2 expression is a prognostic marker for the activated B-cell-like type of diffuse large B-cell lymphoma. J. Clin. Oncol. 24 (2006) 961-968
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 961-968
-
-
Iqbal, J.1
Neppalli, V.T.2
Wright, G.3
Dave, B.J.4
Horsman, D.E.5
Rosenwald, A.6
Lynch, J.7
Hans, C.P.8
Weisenburger, D.D.9
Greiner, T.C.10
-
25
-
-
33749846225
-
Role of Bax and Bak in mitochondrial morphogenesis
-
Karbowski M., Norris K.L., Cleland M.M., Jeong S.Y., and Youle R.J. Role of Bax and Bak in mitochondrial morphogenesis. Nature 443 (2006) 658-662
-
(2006)
Nature
, vol.443
, pp. 658-662
-
-
Karbowski, M.1
Norris, K.L.2
Cleland, M.M.3
Jeong, S.Y.4
Youle, R.J.5
-
26
-
-
0030695837
-
Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL
-
Kelekar A., Chang B.S., Harlan J.E., Fesik S.W., and Thompson C.B. Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL. Mol. Cell. Biol. 17 (1997) 7040-7046
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 7040-7046
-
-
Kelekar, A.1
Chang, B.S.2
Harlan, J.E.3
Fesik, S.W.4
Thompson, C.B.5
-
27
-
-
0032146987
-
Bcl-2-family proteins: The role of the BH3 domain in apoptosis
-
Kelekar A., and Thompson C.B. Bcl-2-family proteins: The role of the BH3 domain in apoptosis. Trends Cell Biol. 8 (1998) 324-330
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 324-330
-
-
Kelekar, A.1
Thompson, C.B.2
-
28
-
-
33751513394
-
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
-
Kim H., Rafiuddin-Shah M., Tu H.C., Jeffers J.R., Zambetti G.P., Hsieh J.J., and Cheng E.H. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies. Nat. Cell Biol. 8 (2006) 1348-1358
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1348-1358
-
-
Kim, H.1
Rafiuddin-Shah, M.2
Tu, H.C.3
Jeffers, J.R.4
Zambetti, G.P.5
Hsieh, J.J.6
Cheng, E.H.7
-
29
-
-
0032479165
-
Abrogation of mitochondrial cytochrome c release and caspase-3 activation in acquired multidrug resistance
-
Kojima H., Endo K., Moriyama H., Tanaka Y., Alnemri E.S., Slapak C.A., Teicher B., Kufe D., and Datta R. Abrogation of mitochondrial cytochrome c release and caspase-3 activation in acquired multidrug resistance. J. Biol. Chem. 273 (1998) 16647-16650
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16647-16650
-
-
Kojima, H.1
Endo, K.2
Moriyama, H.3
Tanaka, Y.4
Alnemri, E.S.5
Slapak, C.A.6
Teicher, B.7
Kufe, D.8
Datta, R.9
-
30
-
-
33750628289
-
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
-
Konopleva M., Contractor R., Tsao T., Samudio I., Ruvolo P.P., Kitada S., Deng X., Zhai D., Shi Y.X., Sneed T., et al. Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. Cancer Cell 10 (2006) 375-388
-
(2006)
Cancer Cell
, vol.10
, pp. 375-388
-
-
Konopleva, M.1
Contractor, R.2
Tsao, T.3
Samudio, I.4
Ruvolo, P.P.5
Kitada, S.6
Deng, X.7
Zhai, D.8
Shi, Y.X.9
Sneed, T.10
-
31
-
-
8944262192
-
Clinical significance of bcl2 and p53 protein expression in diffuse large B-cell lymphoma: A population-based study
-
Kramer M.H., Hermans J., Parker J., Krol A.D., Kluin-Nelemans J.C., Haak H.L., van Groningen K., van Krieken J.H., de Jong D., and Kluin P.M. Clinical significance of bcl2 and p53 protein expression in diffuse large B-cell lymphoma: A population-based study. J. Clin. Oncol. 14 (1996) 2131-2138
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 2131-2138
-
-
Kramer, M.H.1
Hermans, J.2
Parker, J.3
Krol, A.D.4
Kluin-Nelemans, J.C.5
Haak, H.L.6
van Groningen, K.7
van Krieken, J.H.8
de Jong, D.9
Kluin, P.M.10
-
32
-
-
0036850312
-
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
Kuwana T., Mackey M.R., Perkins G., Ellisman M.H., Latterich M., Schneiter R., Green D.R., and Newmeyer D.D. Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell 111 (2002) 331-342
-
(2002)
Cell
, vol.111
, pp. 331-342
-
-
Kuwana, T.1
Mackey, M.R.2
Perkins, G.3
Ellisman, M.H.4
Latterich, M.5
Schneiter, R.6
Green, D.R.7
Newmeyer, D.D.8
-
33
-
-
13944277343
-
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
Kuwana T., Bouchier-Hayes L., Chipuk J.E., Bonzon C., Sullivan B.A., Green D.R., and Newmeyer D.D. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol. Cell 17 (2005) 525-535
-
(2005)
Mol. Cell
, vol.17
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
Bonzon, C.4
Sullivan, B.A.5
Green, D.R.6
Newmeyer, D.D.7
-
34
-
-
0037395017
-
BH3 domains as BCL-2 inhibitors: Prototype cancer therapeutics
-
Letai A. BH3 domains as BCL-2 inhibitors: Prototype cancer therapeutics. Expert Opin. Biol. Ther. 3 (2003) 293-304
-
(2003)
Expert Opin. Biol. Ther.
, vol.3
, pp. 293-304
-
-
Letai, A.1
-
35
-
-
26444558130
-
Pharmacological manipulation of Bcl-2 family members to control cell death
-
Letai A. Pharmacological manipulation of Bcl-2 family members to control cell death. J. Clin. Invest. 115 (2005) 2648-2655
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2648-2655
-
-
Letai, A.1
-
36
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A., Bassik M.C., Walensky L.D., Sorcinelli M.D., Weiler S., and Korsmeyer S.J. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2 (2002) 183-192
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
37
-
-
4544340539
-
Anti-apoptotic BCL-2 is required for maintenance of a model leukemia
-
Letai A., Beard C., Sorcinelli M., and Korsmeyer S.J. Anti-apoptotic BCL-2 is required for maintenance of a model leukemia. Cancer Cell 6 (2004) 241-249
-
(2004)
Cancer Cell
, vol.6
, pp. 241-249
-
-
Letai, A.1
Beard, C.2
Sorcinelli, M.3
Korsmeyer, S.J.4
-
38
-
-
34249996230
-
'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-X(L) inhibitor ABT-737
-
Lin X., Morgan-Lappe S., Huang X., Li L., Zakula D.M., Vernetti L.A., Fesik S.W., and Shen Y. 'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-X(L) inhibitor ABT-737. Oncogene 26 (2006) 3972-3979
-
(2006)
Oncogene
, vol.26
, pp. 3972-3979
-
-
Lin, X.1
Morgan-Lappe, S.2
Huang, X.3
Li, L.4
Zakula, D.M.5
Vernetti, L.A.6
Fesik, S.W.7
Shen, Y.8
-
39
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X., Budihardjo I., Zou H., Slaughter C., and Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94 (1998) 481-490
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
40
-
-
0036091728
-
Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis
-
Marani M., Tenev T., Hancock D., Downward J., and Lemoine N.R. Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis. Mol. Cell. Biol. 22 (2002) 3577-3589
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3577-3589
-
-
Marani, M.1
Tenev, T.2
Hancock, D.3
Downward, J.4
Lemoine, N.R.5
-
41
-
-
5244224827
-
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
-
Muchmore S.W., Sattler M., Liang H., Meadows R.P., Harlan J.E., Yoon H.S., Nettesheim D., Chang B.S., Thompson C.B., Wong S.L., et al. X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature 381 (1996) 335-341
-
(1996)
Nature
, vol.381
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
Meadows, R.P.4
Harlan, J.E.5
Yoon, H.S.6
Nettesheim, D.7
Chang, B.S.8
Thompson, C.B.9
Wong, S.L.10
-
42
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf T., Elmore S.W., Shoemaker A.R., Armstrong R.C., Augeri D.J., Belli B.A., Bruncko M., Deckwerth T.L., Dinges J., Hajduk P.J., et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 435 (2005) 677-681
-
(2005)
Nature
, vol.435
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
-
43
-
-
0348148880
-
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1
-
Opferman J.T., Letai A., Beard C., Sorcinelli M.D., Ong C.C., and Korsmeyer S.J. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature 426 (2003) 671-676
-
(2003)
Nature
, vol.426
, pp. 671-676
-
-
Opferman, J.T.1
Letai, A.2
Beard, C.3
Sorcinelli, M.D.4
Ong, C.C.5
Korsmeyer, S.J.6
-
44
-
-
0030614915
-
Structure of Bcl-xL-Bak peptide complex: Recognition between regulators of apoptosis
-
Sattler M., Liang H., Nettesheim D., Meadows R.P., Harlan J.E., Eberstadt M., Yoon H.S., Shuker S.B., Chang B.S., Minn A.J., et al. Structure of Bcl-xL-Bak peptide complex: Recognition between regulators of apoptosis. Science 275 (1997) 983-986
-
(1997)
Science
, vol.275
, pp. 983-986
-
-
Sattler, M.1
Liang, H.2
Nettesheim, D.3
Meadows, R.P.4
Harlan, J.E.5
Eberstadt, M.6
Yoon, H.S.7
Shuker, S.B.8
Chang, B.S.9
Minn, A.J.10
-
45
-
-
0037418843
-
BAX and BAK regulation of endoplasmic reticulum Ca2+: A control point for apoptosis
-
Scorrano L., Oakes S.A., Opferman J.T., Cheng E.H., Sorcinelli M.D., Pozzan T., and Korsmeyer S.J. BAX and BAK regulation of endoplasmic reticulum Ca2+: A control point for apoptosis. Science 300 (2003) 135-139
-
(2003)
Science
, vol.300
, pp. 135-139
-
-
Scorrano, L.1
Oakes, S.A.2
Opferman, J.T.3
Cheng, E.H.4
Sorcinelli, M.D.5
Pozzan, T.6
Korsmeyer, S.J.7
-
46
-
-
0021821903
-
Involvement of the bcl-2 gene in human follicular lymphoma
-
Tsujimoto Y., Cossman J., Jaffe E., and Croce C.M. Involvement of the bcl-2 gene in human follicular lymphoma. Science 228 (1985) 1440-1443
-
(1985)
Science
, vol.228
, pp. 1440-1443
-
-
Tsujimoto, Y.1
Cossman, J.2
Jaffe, E.3
Croce, C.M.4
-
47
-
-
33750834023
-
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
-
van Delft M.F., Wei A.H., Mason K.D., Vandenberg C.J., Chen L., Czabotar P.E., Willis S.N., Scott C.L., Day C.L., Cory S., et al. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. Cancer Cell 10 (2006) 389-399
-
(2006)
Cancer Cell
, vol.10
, pp. 389-399
-
-
van Delft, M.F.1
Wei, A.H.2
Mason, K.D.3
Vandenberg, C.J.4
Chen, L.5
Czabotar, P.E.6
Willis, S.N.7
Scott, C.L.8
Day, C.L.9
Cory, S.10
-
48
-
-
0035890085
-
The expanding role of mitochondria in apoptosis
-
Wang X. The expanding role of mitochondria in apoptosis. Genes Dev. 15 (2001) 2922-2933
-
(2001)
Genes Dev.
, vol.15
, pp. 2922-2933
-
-
Wang, X.1
-
49
-
-
0034663829
-
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
-
Wei M.C., Lindsten T., Mootha V.K., Weiler S., Gross A., Ashiya M., Thompson C.B., and Korsmeyer S.J. tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c. Genes Dev. 14 (2000) 2060-2071
-
(2000)
Genes Dev.
, vol.14
, pp. 2060-2071
-
-
Wei, M.C.1
Lindsten, T.2
Mootha, V.K.3
Weiler, S.4
Gross, A.5
Ashiya, M.6
Thompson, C.B.7
Korsmeyer, S.J.8
-
50
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei M.C., Zong W.X., Cheng E.H., Lindsten T., Panoutsakopoulou V., Ross A.J., Roth K.A., MacGregor G.R., Thompson C.B., and Korsmeyer S.J. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 292 (2001) 727-730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
51
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
Willis S.N., Fletcher J.I., Kaufmann T., van Delft M.F., Chen L., Czabotar P.E., Ierino H., Lee E.F., Fairlie W.D., Bouillet P., et al. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 315 (2007) 856-859
-
(2007)
Science
, vol.315
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
van Delft, M.F.4
Chen, L.5
Czabotar, P.E.6
Ierino, H.7
Lee, E.F.8
Fairlie, W.D.9
Bouillet, P.10
-
52
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
Zong W.X., Lindsten T., Ross A.J., MacGregor G.R., and Thompson C.B. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev. 15 (2001) 1481-1486
-
(2001)
Genes Dev.
, vol.15
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
-
53
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
Zong W.X., Ditsworth D., Bauer D.E., Wang Z.Q., and Thompson C.B. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev. 18 (2004) 1272-1282
-
(2004)
Genes Dev.
, vol.18
, pp. 1272-1282
-
-
Zong, W.X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.Q.4
Thompson, C.B.5
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