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Volumn 52, Issue 5, 2011, Pages 849-864

Akt, 14-3-3ζ, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma

Author keywords

14 3 3zeta ( ); Akt; B cell lymphoma; DLBCL; drug resistance; invasion; vimentin

Indexed keywords

CHAPERONE; CYCLOPHOSPHAMIDE; DOXORUBICIN; ENOLASE; ENOLASE 1; EZRIN; GLYCINE HYDROXYMETHYLTRANSFERASE; PREDNISONE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN P53; SMALL INTERFERING RNA; SORCIN; STRATIFIN; TRIOSEPHOSPHATE ISOMERASE; TRIOSEPHOSPHATE ISOMERASE 1; TUBULIN SPECIFIC CHAPERONE B; UNCLASSIFIED DRUG; VIMENTIN; VINCRISTINE; WITHAFERIN A;

EID: 79955070726     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2010.551793     Document Type: Article
Times cited : (41)

References (87)
  • 1
    • 34250743767 scopus 로고    scopus 로고
    • Diffuse large B cell lymphoma
    • Ng AK. Diffuse large B cell lymphoma. Semin Radiat Oncol 2007;17:169-75.
    • (2007) Semin Radiat Oncol , vol.17 , pp. 169-175
    • Ng, A.K.1
  • 5
    • 0032818721 scopus 로고    scopus 로고
    • Somatic mutations and intraclonal variations in the rearranged V(K) genes of B-non-Hodgkin's lymphoma cell lines
    • Gabay C, Ben-Bassat H, Schlesinger M, Laskov R. Somatic mutations and intraclonal variations in the rearranged Vkappa genes of B-non-Hodgkin's lymphoma cell lines. Eur J Immunol 1999;63:180-191. (Pubitemid 29406735)
    • (1999) European Journal of Haematology , vol.63 , Issue.3 , pp. 180-191
    • Gabay, C.1    Ben-Bassat, H.2    Schlesinger, M.3    Laskov, R.4
  • 7
    • 0026531547 scopus 로고
    • A human B-cell lymphoma line with a de novo multidrug resistance phenotype
    • Mohammad RM, Mohamed AN, KuKuruga M, Smith MR, al-Katib A. A human B-cell lymphoma line with a de novo multidrug resistance phenotype. Cancer 1992;69:1468-1474.
    • (1992) Cancer , vol.69 , pp. 1468-1474
    • Mohammad, R.M.1    Mohamed, A.N.2    KuKuruga, M.3    Smith, M.R.4    Al-Katib, A.5
  • 8
    • 69249146105 scopus 로고    scopus 로고
    • 14-3-3zeta mediates resistance of diffuse large B cell lymphoma to an anthracycline-based chemotherapeutic regimen
    • Maxwell SA, Li Z, Jaya D, Ballard S, Ferrell J, Fu H. 14-3-3zeta mediates resistance of diffuse large B cell lymphoma to an anthracycline-based chemotherapeutic regimen. J Biol Chem 2009;284:22379-22389.
    • (2009) J Biol Chem , vol.284 , pp. 22379-22389
    • Maxwell, S.A.1    Li, Z.2    Jaya, D.3    Ballard, S.4    Ferrell, J.5    Fu, H.6
  • 10
    • 0025828515 scopus 로고
    • Possible role of acrolein in 4-hydroperoxycyclophosphamide-induced cell damage in vitro
    • Blomgren, H, Hallstrom M. Possible role of acrolein in 4-hydroperoxycyclophosphamide-induced cell damage in vitro. Methods Find Exp Clin Pharmacol 1991;13:11-14.
    • (1991) Methods Find Exp Clin Pharmacol , vol.13 , pp. 11-14
    • Blomgren, H.1    Hallstrom, M.2
  • 11
    • 0031852098 scopus 로고    scopus 로고
    • A novel one-step, highly sensitive fluorometric assay to evaluate cell- mediated cytotoxicity
    • DOI 10.1016/S0022-1759(98)00028-3, PII S0022175998000283
    • Nociari MM, Shalev A, Benias P, Russo C. A novel one-step, highly sensitive fluorometric assay to evaluate cell-mediated cytotoxicity. J Immunol Methods 1998;213:157-167. (Pubitemid 28332808)
    • (1998) Journal of Immunological Methods , vol.213 , Issue.2 , pp. 157-167
    • Nociari, M.M.1    Shalev, A.2    Benias, P.3    Russo, C.4
  • 12
    • 0028344958 scopus 로고
    • 3H]thymidine incorporation assay
    • DOI 10.1016/0022-1759(94)90396-4
    • Ahmed SA, Gogal RM Jr, Walsh JE. A new rapid and simple non-radioactive assay to monitor and determine the proliferation of lymphocytes: an alternative to [3H]thymidine incorporation assay. J Immunol Methods 1994;170:211-224. (Pubitemid 24122510)
    • (1994) Journal of Immunological Methods , vol.170 , Issue.2 , pp. 211-224
    • Ahmed, S.A.1    Gogal Jr., R.M.2    Walsh, J.E.3
  • 13
    • 57349109379 scopus 로고    scopus 로고
    • Molecular profile of endothelial invasion of three-dimensional collagen matrices: Insights into angiogenic sprout induction in wound healing
    • DOI 10.1152/ajpcell.00336.2008
    • Su SC, Mendoza EA, Kwak HI, Bayless KJ. Molecular profile of endothelial invasion of three-dimensional collagen matrices: insights into angiogenic sprout induction in would healing. Am J Physiol Cell Physiol 2008;295:C1215-C1229. (Pubitemid 352790352)
    • (2008) American Journal of Physiology - Cell Physiology , vol.295 , Issue.5
    • Su, S.-C.1    Mendoza, E.A.2    Kwak, H.-I.3    Bayless, K.J.4
  • 14
    • 33846689213 scopus 로고    scopus 로고
    • Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling
    • Fisher KE, Pop A, Koh W, Anthis NJ, Saunders WB, Davis GE. Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling. Mol Cancer 2006;5:69.
    • (2006) Mol Cancer , vol.5 , pp. 69
    • Fisher, K.E.1    Pop, A.2    Koh, W.3    Anthis, N.J.4    Saunders, W.B.5    Davis, G.E.6
  • 15
    • 74949103571 scopus 로고    scopus 로고
    • Investigating endothelial invasion and sprouting behavior in three-dimensional collagen matrices
    • Bayless KJ, Kwak HI, Su SC. Investigating endothelial invasion and sprouting behavior in three-dimensional collagen matrices. Nat Protoc 2009;4:1888-1898.
    • (2009) Nat Protoc , vol.4 , pp. 1888-1898
    • Bayless, K.J.1    Kwak, H.I.2    Su, S.C.3
  • 16
    • 0024533623 scopus 로고
    • Oxidative metabolism of cyclophosphamide: Identification of the hepatic monooxygenase catalysts of drug activation
    • Clarke L, Waxman DJ. Oxidative metabolism of cyclopho-sphamide: identification of the hepatic monooxygenase catalysts of drug activation. Cancer Res 1989;49:2344-2350. (Pubitemid 19125559)
    • (1989) Cancer Research , vol.49 , Issue.9 , pp. 2344-2350
    • Clarke, L.1    Waxman, D.J.2
  • 18
    • 0036238201 scopus 로고    scopus 로고
    • Expression profiling in transformed human B cells: Influence of Btk mutations and comparison to B cell lymphomas using filter and oligonucleotide arrays
    • DOI 10.10 02/1521-41 41(2002 04)32:4<9 82::AID-IMMU9 82>3.0.CO;2-I
    • Islam TC, Lindvall J, Wennborg A, Brandén LJ, Rabbani H, Smith CI. Expression profiling in transformed human B cells: influence of Btk mutations and comparison to B cell lymphomas using filter and oligonucleotide arrays. Eur J Immunol 2002;32:982-993. (Pubitemid 34428813)
    • (2002) European Journal of Immunology , vol.32 , Issue.4 , pp. 982-993
    • Islam, T.C.1    Lindvall, J.2    Wennborg, A.3    Branden, L.J.4    Rabbani, H.5    Smith, C.I.E.6
  • 19
    • 0026095575 scopus 로고
    • The kinetics of vimentin RNA and protein expression in interleukin 2-stimulated T lymphocytes
    • Podolin PL, Prystowsky MB. The kinetics of vimentin RNA and protein expression in interleukin 2-stimulated T lymphocytes. J Biol Chem 1991;266:5870-5875.
    • (1991) J Biol Chem , vol.266 , pp. 5870-5875
    • Podolin, P.L.1    Prystowsky, M.B.2
  • 22
    • 33749991874 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase-mediated glucose metabolism coincides with resveratrol-induced cell cycle arrest in human diffuse large B-cell lymphomas
    • DOI 10.1016/j.bcp.2006.08.009, PII S0006295206004990
    • Faber AC, Dufort FJ, Blair D, Wagner D, Roberts MF, Chiles TC. Inhibition of phosphatidylinositol 3-kinase-mediated glucose metabolism coincides with resveratrol-induced cell cycle arrest in human diffuse large B-cell lymphomas. Biochem Pharmacol 2006;72:1246-1256. (Pubitemid 44572191)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.10 , pp. 1246-1256
    • Faber, A.C.1    Dufort, F.J.2    Blair, D.3    Wagner, D.4    Roberts, M.F.5    Chiles, T.C.6
  • 24
    • 70449494636 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting akt signaling through mTORC2
    • Gupta M, Ansell SM, Novak AJ, Kumar S, Kaufmann SH, Witzig TE. Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2. Blood 2009;114:2926-2935.
    • (2009) Blood , vol.114 , pp. 2926-2935
    • Gupta, M.1    Ansell, S.M.2    Novak, A.J.3    Kumar, S.4    Kaufmann, S.H.5    Witzig, T.E.6
  • 25
    • 77951693077 scopus 로고    scopus 로고
    • High immuno-histochemical expression of p-AKT predicts inferior survival in patients with diffuse large B-cell lymphoma treated with immunochemotherapy
    • Hasselblom S, Hansson U, Olsson M, et al. High immunohistochemical expression of p-AKT predicts inferior survival in patients with diffuse large B-cell lymphoma treated with immunochemotherapy. Br J Haematol 2010;149: 560-568.
    • (2010) Br J Haematol , vol.149 , pp. 560-568
    • Hasselblom, S.1    Hansson, U.2    Olsson, M.3
  • 26
    • 0025870703 scopus 로고
    • B-cell lymphoma with vimentin-positive cytoplasmic inclusions
    • Lertprasertsuke N, Tsutsumi Y, Maruyama T. B-cell lymphoma with vimentin-positive cytoplasmic inclusions. Acta Pathol Jpn 1991;41:473-479.
    • (1991) Acta Pathol Jpn , vol.41 , pp. 473-479
    • Lertprasertsuke, N.1    Tsutsumi, Y.2    Maruyama, T.3
  • 28
    • 0026178536 scopus 로고
    • Cytokeratin expression and vimentin content in large cell anaplastic lymphomas and other non-Hodgkin's lymphomas
    • Gustmann C, Altmannsberger M, Osborn M, Griesser H, Feller AC. Cytokeratin expression and vimentin content in large cell anaplastic lymphomas and other non-Hodgkin's lymphomas. Am J Pathol 1991;138:1413-1422.
    • (1991) Am J Pathol , vol.138 , pp. 1413-1422
    • Gustmann, C.1    Altmannsberger, M.2    Osborn, M.3    Griesser, H.4    Feller, A.C.5
  • 30
    • 68849113475 scopus 로고    scopus 로고
    • Introducing intermediate filaments: From discovery to disease
    • Eriksson JE, Dechat T, Grin B, et al. Introducing intermediate filaments: from discovery to disease. J Clin Invest 2009;119: 1763-1771.
    • (2009) J Clin Invest , vol.119 , pp. 1763-1771
    • Eriksson, J.E.1    Dechat, T.2    Grin, B.3
  • 31
    • 77953484480 scopus 로고    scopus 로고
    • Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition
    • Mendez MG, Kojima SI, Goldman RD. Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition. FASEB J 2010;24:1838-1851.
    • (2010) FASEB J , vol.24 , pp. 1838-1851
    • Mendez, M.G.1    Kojima, S.I.2    Goldman, R.D.3
  • 32
    • 70349165716 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer metastasis: Mechanisms, markers and strategies to overcome drug resistance in the clinic
    • Voulgari A, Pintzas A. Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic. Biochim Biophys Acta 2009;1796:75-90.
    • (2009) Biochim Biophys Acta , vol.1796 , pp. 75-90
    • Voulgari, A.1    Pintzas, A.2
  • 35
    • 16644392631 scopus 로고    scopus 로고
    • Reduction of 9-nitrocamptothecin-triggered apoptosis in DU-145 human prostate cancer cells by ectopic expression of 14-3-3zeta
    • Chatterjee D, Goldman M, Braastad CD, et al. Reduction of 9-nitrocamptothecin-triggered apoptosis in DU-145 human prostate cancer cells by ectopic expression of 14-3-3zeta. Int J Oncol 2004;25:503-509.
    • (2004) Int J Oncol , vol.25 , pp. 503-509
    • Chatterjee, D.1    Goldman, M.2    Braastad, C.D.3
  • 36
    • 65949124697 scopus 로고    scopus 로고
    • 14-3-3zeta overexpression defines high risk for breast cancer recurrence and promotes cancer cell survival
    • Neal CL, Yao J, Yang W, et al. 14-3-3zeta overexpression defines high risk for breast cancer recurrence and promotes cancer cell survival. Cancer Res 2009;69:3425-3432.
    • (2009) Cancer Res , vol.69 , pp. 3425-3432
    • Neal, C.L.1    Yao, J.2    Yang, W.3
  • 37
    • 38349103951 scopus 로고    scopus 로고
    • Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation
    • Li Z, Zhao J, Du Y, et al. Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation. Proc Natl Acad Sci USA 2008;105: 162-167.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 162-167
    • Li, Z.1    Zhao, J.2    Du, Y.3
  • 39
    • 0346963162 scopus 로고    scopus 로고
    • Two 14-3-3 binding motifs are required for stable association of forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding
    • DOI 10.1021/bi0352724
    • Obsil T, Ghirlando R, Anderson DE, Hickman AB, Dyda F. Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding. Biochemistry 2003;42:15264-15272. (Pubitemid 38031725)
    • (2003) Biochemistry , vol.42 , Issue.51 , pp. 15264-15272
    • Obsil, T.1    Ghirlando, R.2    Anderson, D.E.3    Hickman, A.B.4    Dyda, F.5
  • 41
    • 33846551199 scopus 로고    scopus 로고
    • Proteomic identification of 14-3-3ζ as an adapter for IGF-1 and Akt/GSK-3β signaling and survival of renal mesangial cells
    • Singh LP, Jiang Y, Cheng DW. Proteomic identification of 14-3-3zeta as an adapter for IGF-1 and Akt/GSK-3beta signaling and survival of renal mesangial cells. Int J Biol Sci 2006;3:27-39. (Pubitemid 46155760)
    • (2007) International Journal of Biological Sciences , vol.3 , Issue.1 , pp. 27-39
    • Singh, L.P.1    Jiang, Y.2    Cheng, D.W.3
  • 42
    • 67651215903 scopus 로고    scopus 로고
    • Serine 58 of 14-3-3zeta is a molecular switch regulating ASK1 and oxidant stress-induced cell death
    • Zhou J, Shao Z, Kerkela R, et al. Serine 58 of 14-3-3zeta is a molecular switch regulating ASK1 and oxidant stress-induced cell death. Mol Cell Biol 2009;29:4167-4176.
    • (2009) Mol Cell Biol , vol.29 , pp. 4167-4176
    • Zhou, J.1    Shao, Z.2    Kerkela, R.3
  • 44
    • 58849120491 scopus 로고    scopus 로고
    • Role of a novel PH-kinase domain interface in PKB/Akt regulation: Structural mechanism for allosteric inhibition
    • Calleja V, Laguerre M, Parker PJ, Larijani B. Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition. PLoS Biol 2009;7:e17.
    • (2009) PLoS Biol , vol.7
    • Calleja, V.1    Laguerre, M.2    Parker, P.J.3    Larijani, B.4
  • 45
    • 15944406764 scopus 로고    scopus 로고
    • PHLPP: A phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
    • DOI 10.1016/j.molcel.2005.03.008
    • Gao T, Furnari F, Newton AC. PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Mol Cell 2005;18:13-24. (Pubitemid 40444644)
    • (2005) Molecular Cell , vol.18 , Issue.1 , pp. 13-24
    • Gao, T.1    Furnari, F.2    Newton, A.C.3
  • 46
    • 33947203621 scopus 로고    scopus 로고
    • PHLPP and a Second Isoform, PHLPP2, Differentially Attenuate the Amplitude of Akt Signaling by Regulating Distinct Akt Isoforms
    • DOI 10.1016/j.molcel.2007.02.017, PII S1097276507001177
    • Brognard J, Sierecki E, Gao T, Newton AC. PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms. Mol Cell 2007;25:917-931. (Pubitemid 46436532)
    • (2007) Molecular Cell , vol.25 , Issue.6 , pp. 917-931
    • Brognard, J.1    Sierecki, E.2    Gao, T.3    Newton, A.C.4
  • 47
    • 77953408308 scopus 로고    scopus 로고
    • Physiological regulation of akt activity and stability
    • Liao Y, Hung MC. Physiological regulation of Akt activity and stability. Am J Transl Res 2010;2:19-42.
    • (2010) Am J Transl Res , vol.2 , pp. 19-42
    • Liao, Y.1    Hung, M.C.2
  • 48
    • 47949125486 scopus 로고    scopus 로고
    • The mammalian target of rapamycin complex 2 controls folding and stability of akt and protein kinase C
    • Facchinetti V, Ouyang W, Wei H, et al. The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J 2008;27:1932-1943.
    • (2008) EMBO J , vol.27 , pp. 1932-1943
    • Facchinetti, V.1    Ouyang, W.2    Wei, H.3
  • 49
    • 27844461512 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in development and cancer: Role of phosphatidylinositol 3′ kinase/AKT pathways
    • DOI 10.1038/sj.onc.1209091, PII 1209091
    • Larue L, Bellacosa A. Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3'-kinase/AKT pathways. Oncogene 2005;24:7443-7454. (Pubitemid 41637984)
    • (2005) Oncogene , vol.24 , Issue.50 , pp. 7443-7454
    • Larue, L.1    Bellacosa, A.2
  • 50
    • 76749134221 scopus 로고    scopus 로고
    • Akt isoforms regulate intermediate filament protein levels in epithelial carcinoma cells
    • Fortier A-M, Themsche CV, Asselin E, Cadrin M. Akt isoforms regulate intermediate filament protein levels in epithelial carcinoma cells. FEBS Lett 2010;584:984-988.
    • (2010) FEBS Lett , vol.584 , pp. 984-988
    • Fortier, A.-M.1    Themsche, C.V.2    Asselin, E.3    Cadrin, M.4
  • 51
    • 0025163797 scopus 로고
    • Molecular basis of homing of intravenously transplanted stem cells to the marrow
    • Tavassoli M, Hardy C. Molecular basis of homing of intra-venously transplanted stem cells to the marrow. Blood 1990;76:1059-1070. (Pubitemid 20318147)
    • (1990) Blood , vol.76 , Issue.6 , pp. 1059-1070
    • Tavassoli, M.1    Hardy, C.L.2
  • 52
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • DOI 10.1016/0092-8674(94)90337-9
    • Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994;76: 301-314. (Pubitemid 24046692)
    • (1994) Cell , vol.76 , Issue.2 , pp. 301-314
    • Springer, T.A.1
  • 54
    • 77149158125 scopus 로고    scopus 로고
    • REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells
    • Rafa L, Dessein AF, Devisme L, et al. REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells. Int J Oncol 2010;36:689-698.
    • (2010) Int J Oncol , vol.36 , pp. 689-698
    • Rafa, L.1    Dessein, A.F.2    Devisme, L.3
  • 55
    • 74549132674 scopus 로고    scopus 로고
    • ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via akt and CREB
    • Park JK, Park SH, So K, Bae IH, Yoo YD, Um HD. ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB. Int J Oncol 2010;36:181-192.
    • (2010) Int J Oncol , vol.36 , pp. 181-192
    • Park, J.K.1    Park, S.H.2    So, K.3    Bae, I.H.4    Yoo, Y.D.5    Um, H.D.6
  • 56
    • 70349590317 scopus 로고    scopus 로고
    • Involvement of pin1 induction in epithelial-mesenchymal transition of tamoxifen-resistant breast cancer cells
    • Kim MR, Choi HK, Cho KB, Kim HS, Kang KW. Involvement of Pin1 induction in epithelial-mesenchymal transition of tamoxifen-resistant breast cancer cells. Cancer Sci 2009;100:1834-1841.
    • (2009) Cancer Sci , vol.100 , pp. 1834-1841
    • Kim, M.R.1    Choi, H.K.2    Cho, K.B.3    Kim, H.S.4    Kang, K.W.5
  • 57
    • 33947192053 scopus 로고    scopus 로고
    • Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
    • DOI 10.1158/0008-5472.CAN-06-1479
    • Cheng GZ, Chan J, Wang Q, Zhang W, Sun CD, Wang LH. Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res 2007;67:1979-1987. (Pubitemid 46424214)
    • (2007) Cancer Research , vol.67 , Issue.5 , pp. 1979-1987
    • Cheng, G.Z.1    Chan, J.2    Wang, Q.3    Zhang, W.4    Sun, C.D.5    Wang, L.-H.6
  • 58
    • 67549134670 scopus 로고    scopus 로고
    • Ritonavir blocks AKT signaling, activates apoptosis and inhibits migration and invasion in ovarian cancer cells
    • Kumar S, Bryant CS, Chamala S, et al. Ritonavir blocks AKT signaling, activates apoptosis and inhibits migration and invasion in ovarian cancer cells. Mol Cancer 2009;8:26.
    • (2009) Mol Cancer , vol.8 , pp. 26
    • Kumar, S.1    Bryant, C.S.2    Chamala, S.3
  • 59
    • 17144398831 scopus 로고    scopus 로고
    • Possible future issues in the treatment of glioblastomas: Special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis
    • DOI 10.1200/JCO.2005.03.089
    • Lefranc F, Brotchi J, Kiss R. Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J Clin Oncol 2005;23:2411-2422. (Pubitemid 46218735)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.10 , pp. 2411-2422
    • Lefranc, F.1    Brotchi, J.2    Kiss, R.3
  • 61
    • 36549089022 scopus 로고    scopus 로고
    • Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells
    • Hutcheson IR, Knowlden JM, Hiscox SE, et al. Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells. Breast Cancer Res 2007;9:R50.
    • (2007) Breast Cancer Res , vol.9
    • Hutcheson, I.R.1    Knowlden, J.M.2    Hiscox, S.E.3
  • 62
    • 62849087279 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion in prostate epithelial cells promotes anoikis resistance and invasion through activation of PI3K/Akt2
    • Moro L, Arbini AA, Yao JL, di Sant'Agnese PA, Marra E, Greco M. Mitochondrial DNA depletion in prostate epithelial cells promotes anoikis resistance and invasion through activation of PI3K/Akt2. Cell Death Differ 2009;16: 571-583.
    • (2009) Cell Death Differ , vol.16 , pp. 571-583
    • Moro, L.1    Arbini, A.A.2    Yao, J.L.3    Di Sant'Agnese, P.A.4    Marra, E.5    Greco, M.6
  • 63
    • 78049345949 scopus 로고    scopus 로고
    • LAPTM4B: A novel cancer-associated gene motivates multidrug resistance through efflux and activating PI3K/AKT signaling
    • Li L, Wei XH, Pan YP, et al. LAPTM4B: a novel cancer-associated gene motivates multidrug resistance through efflux and activating PI3K/AKT signaling. Oncogene 2010;29: 5785-5795.
    • (2010) Oncogene , vol.29 , pp. 5785-5795
    • Li, L.1    Wei, X.H.2    Pan, Y.P.3
  • 64
    • 79955075562 scopus 로고    scopus 로고
    • Vimentin is a novel AKT1 target mediating motility and invasion
    • Sep 20. [Epub ahead of print]
    • Zhu QS, Rosenblatt K, Huang KL, et al. Vimentin is a novel AKT1 target mediating motility and invasion. Oncogene 2010 Sep 20. [Epub ahead of print].
    • (2010) Oncogene
    • Zhu, Q.S.1    Rosenblatt, K.2    Huang, K.L.3
  • 65
    • 77956301589 scopus 로고    scopus 로고
    • Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies
    • Lahat G, Zhu QS, Huang KL, et al. Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies. PLoS One 2010;5:e10105.
    • (2010) PLoS One , vol.5
    • Lahat, G.1    Zhu, Q.S.2    Huang, K.L.3
  • 66
    • 29944447730 scopus 로고    scopus 로고
    • HSP90 protects apoptotic cleavage of vimentin in geldanamycin-induced apoptosis
    • Zhang MH, Lee JS, Kim HJ, et al. HSP90 protects apoptotic cleavage of vimentin in geldanamycin-induced apoptosis. Mol Cell Biochem 2006;281:111-121.
    • (2006) Mol Cell Biochem , vol.281 , pp. 111-121
    • Zhang, M.H.1    Lee, J.S.2    Kim, H.J.3
  • 68
    • 51649126148 scopus 로고    scopus 로고
    • Tyrosine kinase inhibition in diffuse large B-cell lymphoma: Molecular basis for antitumor activity and drug resistance of dasatinib
    • Yang C, Lu P, Lee FY, et al. Tyrosine kinase inhibition in diffuse large B-cell lymphoma: molecular basis for antitumor activity and drug resistance of dasatinib. Leukemia 2008;22: 1755-1766.
    • (2008) Leukemia , vol.22 , pp. 1755-1766
    • Yang, C.1    Lu, P.2    Lee, F.Y.3
  • 73
    • 23844471567 scopus 로고    scopus 로고
    • Immunohistochemical expression of multidrug resistance proteins as a predictor of poor response to chemotherapy and prognosis in patients with nodal diffuse large B-cell lymphoma
    • DOI 10.1159/000086984
    • Ohsawa M, Ikura Y, Fukushima H, et al. Immunohistochemical expression of multidrug resistance proteins as a predictor of poor response to chemotherapy and prognosis in patients with nodal diffuse large B-cell lymphoma. Oncology 2005;68: 422-431. (Pubitemid 41160973)
    • (2005) Oncology , vol.68 , Issue.4-6 , pp. 422-431
    • Ohsawa, M.1    Ikura, Y.2    Fukushima, H.3    Shirai, N.4    Sugama, Y.5    Suekane, T.6    Hirayama, M.7    Hino, M.8    Ueda, M.9
  • 74
    • 77951442337 scopus 로고    scopus 로고
    • Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1
    • Yecies D, Carlson NE, Deng J, Letai A. Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1. Blood 2010;115:3304-3313.
    • (2010) Blood , vol.115 , pp. 3304-3313
    • Yecies, D.1    Carlson, N.E.2    Deng, J.3    Letai, A.4
  • 76
    • 0033521010 scopus 로고    scopus 로고
    • Cortical actin organization: Lessons from ERM (Ezrin/Radixin/Moesin) proteins
    • Tsukita S, Yonemura S. Cortical actin organization: Lessons from ERM (ezrin/radixin/moesin) proteins. J Biol Chem 1999;274:34507-34510. (Pubitemid 129509480)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.49 , pp. 34507-34510
    • Tsukita, S.1    Yonemura, S.2
  • 77
    • 2542588542 scopus 로고    scopus 로고
    • Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes
    • DOI 10.1111/j.1365-2567.2004.01882.x
    • Ivetic A, Ridley AJ. Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes. Immunology 2004;112:165-176. (Pubitemid 38703562)
    • (2004) Immunology , vol.112 , Issue.2 , pp. 165-176
    • Ivetic, A.1    Ridley, A.J.2
  • 78
    • 33645066349 scopus 로고    scopus 로고
    • Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia - An in vivo study
    • Verrills NM, Liem NL, Liaw TYE, Hood BD, Lock RB, Kavallaris M. Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia - an in vivo study. Proteomics 2006;6:1681-1694.
    • (2006) Proteomics , vol.6 , pp. 1681-1694
    • Verrills, N.M.1    Liem, N.L.2    Liaw, T.Y.E.3    Hood, B.D.4    Lock, R.B.5    Kavallaris, M.6
  • 80
    • 45149104139 scopus 로고    scopus 로고
    • A subcelluar proteomic investigation into vincristine-resistant gastric cancer cell line
    • DOI 10.1002/jcb.21687
    • Yang YX, Chen ZC, Zhang GY, Yi H, Xiao ZQ. A subcelluar proteomic investigation into vincristine-resistant gastric cancer cell line. J Cell Biochem 2008;104:1010-1021. (Pubitemid 351830847)
    • (2008) Journal of Cellular Biochemistry , vol.104 , Issue.3 , pp. 1010-1021
    • Yang, Y.-X.1    Chen, Z.-C.2    Zhang, G.-Y.3    Yi, H.4    Xiao, Z.-Q.5
  • 82
    • 0023234519 scopus 로고
    • Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein
    • Cornwell MM, Pastan I, Gottesman MM. Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein. J Biol Chem 1987;262:2166-2170. (Pubitemid 17102655)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.5 , pp. 2166-2170
    • Cornwell, M.M.1    Pastan, I.2    Gottesman, M.M.3
  • 83
    • 0025261421 scopus 로고
    • Effect of exposure to calcium entry blockers on doxorubicin accumulation and cytotoxicity in multidrug-resistant cells
    • Bruno NA, Slate DL. Effect of exposure to calcium entry blockers on doxorubicin accumulation and cytotoxicity in multidrug-resistant cells. J Natl Cancer Inst 1990;82:419-424. (Pubitemid 20108035)
    • (1990) Journal of the National Cancer Institute , vol.82 , Issue.5 , pp. 419-424
    • Bruno, N.A.1    Slate, D.L.2
  • 84
    • 33645528750 scopus 로고    scopus 로고
    • Identification of 14-3-3sigma as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis
    • Liu Y, Liu H, Han B, Zhang JT. Identification of 14-3-3sigma as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis. Cancer Res 2006;66: 3248-3255.
    • (2006) Cancer Res , vol.66 , pp. 3248-3255
    • Liu, Y.1    Liu, H.2    Han, B.3    Zhang, J.T.4
  • 85
    • 67349214378 scopus 로고    scopus 로고
    • Neuroendocrine differentiation is involved in chemoresistance induced by EGF in prostate cancer cells
    • Li Y, Chen HQ, Chen MF, et al. Neuroendocrine differentiation is involved in chemoresistance induced by EGF in prostate cancer cells. Life Sci 2009;84:882-887.
    • (2009) Life Sci , vol.84 , pp. 882-887
    • Li, Y.1    Chen, H.Q.2    Chen, M.F.3
  • 86
    • 69749115434 scopus 로고    scopus 로고
    • Role of caveolin 1, E-cadherin, enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells
    • Selga E, Morales C, Noé V, Peinado MA, Ciudad CJ. Role of caveolin 1, E-cadherin, enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells. BMC Med Genomics 2008;1:35.
    • (2008) BMC Med Genomics , vol.1 , pp. 35
    • Selga, E.1    Morales, C.2    Noé, V.3    Peinado, M.A.4    Ciudad, C.J.5
  • 87
    • 0033770089 scopus 로고    scopus 로고
    • Identification of genes differentially expressed in association with acquired cisplatin resistance
    • Johnsson A, Zeelenberg I, Min Y, et al. Identification of genes differentially expressed in association with acquired cisplatin resistance. Br J Cancer 2000;83:1047-1054.
    • (2000) Br J Cancer , vol.83 , pp. 1047-1054
    • Johnsson, A.1    Zeelenberg, I.2    Min, Y.3


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