Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 2, 2004, Pages 540-545

  Mitsiades, Constantine S ^a,b   Mitsiades, Nicholas S ^a,b   McMullan, Ciaran J ^a,b   Poulaki, Vassiliki ^b   Shringarpure, Reshma ^a,b   Hideshima, Teru ^a,b   Akiyama, Masaharu ^a,b   Chauhan, Dharminder ^a,b   Munshi, Nikhil ^a,b   Gu, Xuesong ^c   Bailey, Charles ^c   Joseph, Marie ^c   Libermann, Towia A ^c   Richon, Victoria M ^d   Marks, Paul A ^e   Anderson, Kenneth C ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

^d Aton Pharma Inc   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Cell signaling; Drug resistance; Oligonucleotide microarrays

Indexed keywords

APOPTOSIS INDUCING FACTOR; BORTEZOMIB; CASPASE INHIBITOR; CYTOTOXIC AGENT; DEXAMETHASONE; HISTONE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; INTERLEUKIN 6 RECEPTOR; ONCOPROTEIN; PHOSPHOTRANSFERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEASOME; PROTEASOME INHIBITOR; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TELOMERASE; THALIDOMIDE DERIVATIVE; TRANSCRIPTION FACTOR; VORINOSTAT;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL GROWTH; CELL SURVIVAL; CELL TRANSFORMATION; CHEMOSENSITIVITY; DNA REPAIR; DNA SYNTHESIS; DRUG EFFECT; DRUG RESISTANCE; ENZYME ASSAY; ENZYME INHIBITION; ENZYME MECHANISM; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; ONCOGENE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

APOPTOSIS; CELL DIVISION; CELL LINE, TUMOR; GENES, TUMOR SUPPRESSOR; HISTONE DEACETYLASES; HUMANS; MULTIPLE MYELOMA; ONCOGENES; SIGNAL TRANSDUCTION;

EID: 9144220841     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2536759100     Document Type: Article

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