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Volumn 403, Issue 6769, 2000, Pages 503-511

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

(31)  Alizadeh, Ash A a   Elsen, Michael B a,j   Davis, R Eric b   Ma, Ch L b   Lossos, Izidore S a   Rosenwald, Andreas c   Boldrick, Jennifer C a   Sabet, Hajeer b   Tran, True b   Yu, Xin b   Powell, John I c   Yang, Liming c   Marü, Gerald E d   Moore, Troy e   Hudson Jr , James e   Lu, Lisheng a   Lewis, David B a   Tibshirani, Robert a   Sherlock, Gavin j   Chan, Wing C h   more..


Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; B CELL LYMPHOMA; CANCER SURVIVAL; CARCINOGENESIS; DNA DETERMINATION; GENETIC ANALYSIS; GENETIC HETEROGENEITY; HUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 0034598746     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35000501     Document Type: Article
Times cited : (8444)

References (50)
  • 1
    • 0001785009 scopus 로고
    • On some morbid appearances of the absorbant glands and spleen
    • Hodgkin, T. On some morbid appearances of the absorbant glands and spleen. Med. -Chir. Trans. 17, 68-114 (1832).
    • (1832) Med. -chir. Trans. , vol.17 , pp. 68-114
    • Hodgkin, T.1
  • 2
    • 0002041031 scopus 로고
    • Über eine eigenartige unter dem Bilde der Pseudoleukamie verlaufende Tuberculose des lymphatischen Apparates
    • Sternberg, C. Über eine eigenartige unter dem Bilde der Pseudoleukamie verlaufende Tuberculose des lymphatischen Apparates. Heilk 19, 21-90 (1898).
    • (1898) Heilk , vol.19 , pp. 21-90
    • Sternberg, C.1
  • 3
    • 0001329373 scopus 로고
    • On the pathological changes in Hodgkins disease, with especial reference to its relation to tuberculosis
    • Reed, D. M. On the pathological changes in Hodgkins disease, with especial reference to its relation to tuberculosis. Johns Hopkins Hosp. Rep. 10, 133-196 (1902).
    • (1902) Johns Hopkins Hosp. Rep. , vol.10 , pp. 133-196
    • Reed, D.M.1
  • 4
    • 0027978937 scopus 로고
    • Classification of lymphoid neoplasms
    • Rosenberg, S. A. Classification of lymphoid neoplasms. Blood 84, 1359-1360 (1994).
    • (1994) Blood , vol.84 , pp. 1359-1360
    • Rosenberg, S.A.1
  • 5
    • 0028064764 scopus 로고
    • A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group
    • Harris, N. L. et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 84, 1361-1392 (1994).
    • (1994) Blood , vol.84 , pp. 1361-1392
    • Harris, N.L.1
  • 6
    • 0000069532 scopus 로고    scopus 로고
    • The Non-Hodgkin's Lymphoma Classification Project: A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma
    • The Non-Hodgkin's Lymphoma Classification Project: A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. Blood 89, 3909-3918 (1997).
    • (1997) Blood , vol.89 , pp. 3909-3918
  • 7
    • 0031928918 scopus 로고    scopus 로고
    • Currenl approaches to the management of non-Hodgkin's lymphoma
    • Vose, J. M. Currenl approaches to the management of non-Hodgkin's lymphoma. Semin. Oncol. 25, 483-491 (1998).
    • (1998) Semin. Oncol. , vol.25 , pp. 483-491
    • Vose, J.M.1
  • 8
    • 0027444652 scopus 로고
    • The International Non-Hodgkin's Lymphoma Prognostic Factors Project: A predictive model for aggressive non-Hodgkin's lymphoma
    • The International Non-Hodgkin's Lymphoma Prognostic Factors Project: A predictive model for aggressive non-Hodgkin's lymphoma. N. Engl. J. Med. 329, 987-994 (1993).
    • (1993) N. Engl. J. Med. , vol.329 , pp. 987-994
  • 9
    • 0031897511 scopus 로고    scopus 로고
    • Somatic hypermutation in normal and transformed human B cells
    • Klein, U. et al. Somatic hypermutation in normal and transformed human B cells. Immunol. Rev. 162, 261-280 (1998).
    • (1998) Immunol. Rev. , vol.162 , pp. 261-280
    • Klein, U.1
  • 10
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • Schena, M., Shalon, D., Davis, R. W. & Brown, P. O. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270, 467-470 (1995).
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 11
    • 0033589283 scopus 로고    scopus 로고
    • Hormone therapy failure in human prostate cancer: Analysis by complementary DNA and tissue microarrays
    • Bubendorf, L. et al. Hormone therapy failure in human prostate cancer: analysis by complementary DNA and tissue microarrays. J. Natl Cancer Inst. 91, 1758-1764 (1999).
    • (1999) J. Natl Cancer Inst. , vol.91 , pp. 1758-1764
    • Bubendorf, L.1
  • 12
    • 0033580456 scopus 로고    scopus 로고
    • Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray
    • Wang, K. et al. Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray. Gene 229, 101-108 (1999).
    • (1999) Gene , vol.229 , pp. 101-108
    • Wang, K.1
  • 13
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub, T. R. et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286, 531-537 (1999).
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1
  • 14
    • 0032534066 scopus 로고    scopus 로고
    • Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays
    • Khan, J. et al. Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays. Cancer Res. 58, 5009-5013 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 5009-5013
    • Khan, J.1
  • 15
    • 13044304179 scopus 로고    scopus 로고
    • Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
    • Perou, C. M. et al. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc. Natl Acad. Sci. USA 96, 9212-217 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 9212-9217
    • Perou, C.M.1
  • 16
    • 0029852580 scopus 로고    scopus 로고
    • Use of a cDNA microarray to analyse gene expression patterns in human cancer
    • DeRisi, J. et al. Use of a cDNA microarray to analyse gene expression patterns in human cancer. Nature Genet. 14, 457-460 (1996).
    • (1996) Nature Genet. , vol.14 , pp. 457-460
    • DeRisi, J.1
  • 17
    • 0033536012 scopus 로고    scopus 로고
    • Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays
    • Alon, U. et al. Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. Proc. Natl Acad. Sci. USA 96, 6745-6750 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 6745-6750
    • Alon, U.1
  • 18
    • 0343382826 scopus 로고    scopus 로고
    • The Lymphochip: A specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes
    • in the press
    • Alizadeh, A. et al. The Lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. Cold Spring Harbor Symp. Quant. Biol. (in the press).
    • Cold Spring Harbor Symp. Quant. Biol.
    • Alizadeh, A.1
  • 19
  • 21
    • 0023943432 scopus 로고
    • Independent prognostic significance of a nuclear proliferation antigen in diffuse large cell lymphomas as determined by the monoclonal antibody Ki-67
    • Grogan, T. M. et al. Independent prognostic significance of a nuclear proliferation antigen in diffuse large cell lymphomas as determined by the monoclonal antibody Ki-67, Blood 71, 1157-1160 (1988).
    • (1988) Blood , vol.71 , pp. 1157-1160
    • Grogan, T.M.1
  • 22
    • 0032773607 scopus 로고    scopus 로고
    • Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6
    • Staudt, L. M., Dent, A. L., Shaffer, A. L. & Yu, X. Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6. Int. J. Immunol 18, 381-403 (1999).
    • (1999) Int. J. Immunol , vol.18 , pp. 381-403
    • Staudt, L.M.1    Dent, A.L.2    Shaffer, A.L.3    Yu, X.4
  • 23
    • 0026636759 scopus 로고
    • Clonal evolution of a follicular lymphoma: Evidence for antigen selection. Proc
    • Bahler, D. W. & Levy, R. Clonal evolution of a follicular lymphoma: evidence for antigen selection. Proc. Natl Acad. Sci. USA 89, 6770-6774 (1992).
    • (1992) Natl Acad. Sci. USA , vol.89 , pp. 6770-6774
    • Bahler, D.W.1    Levy, R.2
  • 24
    • 0011615566 scopus 로고    scopus 로고
    • eds Weir. D., Blackwell, C., Herzenberg, L. & Herzenberg, L. Blackwell Scientific, Oxford
    • Liu, Y. -J. & Banchereau, J. in Handbook of Experimental Immunology (eds Weir. D., Blackwell, C., Herzenberg, L. & Herzenberg, L.) 93.1-93.9 [Blackwell Scientific, Oxford, 1996].
    • (1996) Handbook of Experimental Immunology , pp. 931-939
    • Liu, Y.-J.1    Banchereau, J.2
  • 25
    • 0028363014 scopus 로고
    • The A-myb gene is preferentially expressed in tonsillar CD38+, CD39-, and slgM-B lymphocytes and in Burkitt's lymphoma cell lines
    • Golay, J., Erba, E., Bernasconi, S., Peri, G. & Introna, M. The A-myb gene is preferentially expressed in tonsillar CD38+, CD39-, and slgM-B lymphocytes and in Burkitt's lymphoma cell lines. J. Immunol. 153, 543-553 (1994).
    • (1994) J. Immunol. , vol.153 , pp. 543-553
    • Golay, J.1    Erba, E.2    Bernasconi, S.3    Peri, G.4    Introna, M.5
  • 26
    • 0030698057 scopus 로고    scopus 로고
    • Augmented expression of a human gene for 8-oxoguanine DNA glycosylase (MutM) in B lymphocytes of the dark zone in lymph node germinal centers. J
    • Kuo, F. C. & Sklan J. Augmented expression of a human gene for 8-oxoguanine DNA glycosylase (MutM) in B lymphocytes of the dark zone in lymph node germinal centers. J. Exp. Med. 186, 1547-1556 (1997).
    • (1997) Exp. Med. , vol.186 , pp. 1547-1556
    • Kuo, F.C.1    Sklan, J.2
  • 27
    • 0029118040 scopus 로고
    • A specific monoclonal antibody (PG-B6) detects expression of the BCL-6 protein in germinal center B cells
    • Flenghi, L. et al. A specific monoclonal antibody (PG-B6) detects expression of the BCL-6 protein in germinal center B cells. Am. J. Pathol. 147, 405-411 (1995).
    • (1995) Am. J. Pathol. , vol.147 , pp. 405-411
    • Flenghi, L.1
  • 28
    • 0029898268 scopus 로고    scopus 로고
    • BCL-6 expression in reactive lymphoid tissue and in B-cell non-Hodgkin's lymphomas
    • Pittaluga, S. et al. BCL-6 expression in reactive lymphoid tissue and in B-cell non-Hodgkin's lymphomas. J. Pathol. 179, 145-150 (1996).
    • (1996) J. Pathol. , vol.179 , pp. 145-150
    • Pittaluga, S.1
  • 29
    • 0029867126 scopus 로고    scopus 로고
    • Molecular cloning of complex chromosomal translocation t(8;14;12)(q24. 1;q32. 3;q24. 1) in a Boskitt lymphoma cell line defines a new gene BCL7A] with homology to caldesmon
    • Zani, V. J. et al. Molecular cloning of complex chromosomal translocation t(8;14;12)(q24. 1;q32. 3;q24. 1) in a Boskitt lymphoma cell line defines a new gene (BCL7A] with homology to caldesmon. Blood 87, 3124-3134 (1996).
    • (1996) Blood 87 , pp. 3124-3134
    • Zani, V.J.1
  • 30
    • 0030763072 scopus 로고    scopus 로고
    • Disruption of the Bcl6 gene results in an impaired germinal center formation
    • Fukuda, T. et al. Disruption of the Bcl6 gene results in an impaired germinal center formation. J. Exp. Med. 186, 439-448 (1997).
    • (1997) J. Exp. Med. , vol.186 , pp. 439-448
    • Fukuda, T.1
  • 31
    • 17144439800 scopus 로고    scopus 로고
    • The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
    • Ye, B. H. et al. The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nature Const. 16, 161-170 (1997).
    • (1997) Nature Const. , vol.16 , pp. 161-170
    • Ye, B.H.1
  • 32
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and gectronal center formation by BCL-6
    • Dent, A. L. Shaffer, A. L., Yu, X., Allman, D. & Staudt, L. M. Control of inflammation, cytokine expression, and gectronal center formation by BCL-6. Science 276, 589-592 (1997).
    • (1997) Science , vol.276 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 33
    • 0032168564 scopus 로고    scopus 로고
    • LMO T-cell translocation oncogenes typify genes activated by chromosomal translocations that alter transcription and developmental processes
    • Rabbits, T. H. LMO T-cell translocation oncogenes typify genes activated by chromosomal translocations that alter transcription and developmental processes. Genes Dev 12, 2651-2657 (1998).
    • (1998) Genes Dev , vol.12 , pp. 2651-2657
    • Rabbits, T.H.1
  • 34
    • 84984756503 scopus 로고    scopus 로고
    • Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma
    • Iida, S. et al. Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma. Nature Genet. 17, 226-230 (1997).
    • (1997) Nature Genet. , vol.17 , pp. 226-230
    • Iida, S.1
  • 35
    • 0029069958 scopus 로고
    • Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE)
    • Matsuyama, T. et al. Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE). Nucleic Acids Res. 23, 2127-2136 (1995).
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2127-2136
    • Matsuyama, T.1
  • 36
    • 15444346834 scopus 로고    scopus 로고
    • Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function
    • Mittrucker, H. W. et al. Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 275, 540-543 (1997).
    • (1997) Science , vol.275 , pp. 540-543
    • Mittrucker, H.W.1
  • 37
    • 0031726359 scopus 로고    scopus 로고
    • Inhibition of fas death signals by FLIPs
    • Tschopp, J., Irmler, M. & Thome, M. Inhibition of fas death signals by FLIPs. Curr. Opin. Immunol. 10, 552-558 (1998).
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 552-558
    • Tschopp, J.1    Irmler, M.2    Thome, M.3
  • 38
    • 0033523684 scopus 로고    scopus 로고
    • The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors
    • Djerbi, M. et al. The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors. J. Exp. Med. 190, 1025-1031 (1999).
    • (1999) J. Exp. Med. , vol.190 , pp. 1025-1031
    • Djerbi, M.1
  • 39
    • 0033523670 scopus 로고    scopus 로고
    • Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein
    • Medema, J. P., de Jong, J., van Hall, T., Melief, C. J. M. & Offringa, R. Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein. J. Exp. Med. 190, 1033-1038 (1999).
    • (1999) J. Exp. Med. , vol.190 , pp. 1033-1038
    • Medema, J.P.1    De Jong, J.2    Van Hall, T.3    Melief, C.J.M.4    Offringa, R.5
  • 40
    • 0027394689 scopus 로고
    • Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma
    • Fisher, R. I. et al. Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma. N. Engl. J. Med. 328, 1002-1006 (1993).
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1002-1006
    • Fisher, R.I.1
  • 41
    • 0025847385 scopus 로고
    • Lymphocyte homing and clinical behavior of non-Hodgkin's lymphoma
    • Jalkanen, S., Joensuu, H., Soderstrom, K. O. & Klemi, P. Lymphocyte homing and clinical behavior of non-Hodgkin's lymphoma, J. Clin. Invest. 87, 1835-1840 (1991).
    • (1991) J. Clin. Invest. , vol.87 , pp. 1835-1840
    • Jalkanen, S.1    Joensuu, H.2    Soderstrom, K.O.3    Klemi, P.4
  • 42
    • 0032846422 scopus 로고    scopus 로고
    • Molecular and immunological dissection of diffuse large B cell lymphoma: CD5-, and CD5-with CD10+ groups may constitute clinically relevant subtypes
    • Harada, S. et al. Molecular and immunological dissection of diffuse large B cell lymphoma: CD5-, and CD5-with CD10+ groups may constitute clinically relevant subtypes. Leukemia 13, 1441-1447 (1999).
    • (1999) Leukemia , vol.13 , pp. 1441-1447
    • Harada, S.1
  • 43
    • 8944262192 scopus 로고    scopus 로고
    • Clinical significance of bcl2 and p53 protein expression in diffuse large B-cell lymphoma: A population-based study
    • Kramer, M. H. et al. Clinical significance of bcl2 and p53 protein expression in diffuse large B-cell lymphoma: a population-based study. J. Clin. Oncol 14, 2131-2138 (1996).
    • (1996) J. Clin. Oncol , vol.14 , pp. 2131-2138
    • Kramer, M.H.1
  • 44
    • 0030861218 scopus 로고    scopus 로고
    • Prognostic value of serum interleukin-6 in diffuse large cell lymphoma
    • Preti, H. A. et al. Prognostic value of serum interleukin-6 in diffuse large cell lymphoma. Ann. Int. Med. 127, 186-194 (1997).
    • (1997) Ann. Int. Med. , vol.127 , pp. 186-194
    • Preti, H.A.1
  • 45
    • 0030985194 scopus 로고    scopus 로고
    • Prognostic significance of Bcl-2 protein expression and Bcl-2 gene rearrangement in diffuse aggressive non-Hodgkin's lymphoma
    • Gascoyne, R. D. et al. Prognostic significance of Bcl-2 protein expression and Bcl-2 gene rearrangement in diffuse aggressive non-Hodgkin's lymphoma. Blood 90, 244-251 (1997).
    • (1997) Blood , vol.90 , pp. 244-251
    • Gascoyne, R.D.1
  • 46
    • 0032211147 scopus 로고    scopus 로고
    • Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma
    • Kramer, M. H. et al. Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma. Blood 92, 3152-3162 (1998).
    • (1998) Blood , vol.92 , pp. 3152-3162
    • Kramer, M.H.1
  • 47
    • 0032476611 scopus 로고    scopus 로고
    • Human immunoglobulin (lg)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells
    • Klein, U., Rajewsky, K. & Kuppers, R. Human immunoglobulin (lg)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J. Exp. Med. 188, 1679-1689 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 1679-1689
    • Klein, U.1    Rajewsky, K.2    Kuppers, R.3
  • 48
    • 0032476617 scopus 로고    scopus 로고
    • Identification of functional human splenic memory B cells by expression of CD148 and CD27
    • Tangye, S. G., Liu, Y. J., Aversa, G., Phillips, J. H. & de Vries, J. E. Identification of functional human splenic memory B cells by expression of CD148 and CD27. J. Exp. Med. 188, 1691-1703 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 1691-1703
    • Tangye, S.G.1    Liu, Y.J.2    Aversa, G.3    Phillips, J.H.4    De Vries, J.E.5
  • 49
    • 0029904294 scopus 로고    scopus 로고
    • BCL-6 expression during B-cell activation
    • Allman, D. et al. BCL-6 expression during B-cell activation. Blood 87, 5257-5268 (1996).
    • (1996) Blood , vol.87 , pp. 5257-5268
    • Allman, D.1
  • 50
    • 0033031437 scopus 로고    scopus 로고
    • DNA arrays for analysis of gene expression
    • Eisen, M. B. & Brown, P. O. DNA arrays for analysis of gene expression. Methods Enzymol. 303, 179-205 (1999).
    • (1999) Methods Enzymol. , vol.303 , pp. 179-205
    • Eisen, M.B.1    Brown, P.O.2


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