메뉴 건너뛰기




Volumn 116, Issue 20, 2010, Pages 4185-4191

Mantle cell lymphoma activation enhances bortezomib sensitivity

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BORTEZOMIB; CYTOSINE DERIVATIVE; CYTOSINE PHOSPHATE GUANOSINE; DEXAMETHASONE; ETOPOSIDE; RETINAL DEHYDROGENASE; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

EID: 78349302466     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-02-268375     Document Type: Article
Times cited : (30)

References (46)
  • 1
    • 50249129796 scopus 로고    scopus 로고
    • Incidence trends of mantle cell lymphoma in the United States between 1992 and 2004
    • Zhou Y, Wang H, Fang W, et al. Incidence trends of mantle cell lymphoma in the United States between 1992 and 2004. Cancer Genet Cytogen. 2008;4(113):791-798.
    • (2008) Cancer Genet Cytogen , vol.4 , Issue.113 , pp. 791-798
    • Zhou, Y.1    Wang, H.2    Fang, W.3
  • 2
    • 0028920013 scopus 로고
    • Patterns of survival in mantle cell lymphoma
    • Zucca E, Roggero E, Pinotti G, et al. Patterns of survival in mantle cell lymphoma. Ann Oncol. 1995;3(6):257-262.
    • (1995) Ann Oncol , vol.3 , Issue.6 , pp. 257-262
    • Zucca, E.1    Roggero, E.2    Pinotti, G.3
  • 3
    • 59149105528 scopus 로고    scopus 로고
    • Improvement of overall survival in advanced stage mantle cell lymphoma
    • Herrmann A, Hoster E, Zwingers T, et al. Improvement of overall survival in advanced stage mantle cell lymphoma. J Clin Oncol. 2009;4(27): 511-518.
    • (2009) J Clin Oncol , vol.4 , Issue.27 , pp. 511-518
    • Herrmann, A.1    Hoster, E.2    Zwingers, T.3
  • 4
    • 34047096557 scopus 로고    scopus 로고
    • Cancer stem cells: Models and concepts
    • Dalerba P, Cho RW, Clarke MF. Cancer stem cells: models and concepts. Annu Rev Med. 2007;58:267-284.
    • (2007) Annu Rev Med , vol.58 , pp. 267-284
    • Dalerba, P.1    Cho, R.W.2    Clarke, M.F.3
  • 5
    • 0037606054 scopus 로고    scopus 로고
    • Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML)
    • Guan Y, Gerhard B, Hogge DE. Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML). Blood. 2003;8(101): 3142-3149.
    • (2003) Blood , vol.8 , Issue.101 , pp. 3142-3149
    • Guan, Y.1    Gerhard, B.2    Hogge, D.E.3
  • 6
    • 0033568250 scopus 로고    scopus 로고
    • Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia
    • Holyoake T, Jiang X, Eaves C, Eaves A. Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia. Blood. 1999;6(94):2056-2064.
    • (1999) Blood , vol.6 , Issue.94 , pp. 2056-2064
    • Holyoake, T.1    Jiang, X.2    Eaves, C.3    Eaves, A.4
  • 7
    • 38549132452 scopus 로고    scopus 로고
    • Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance
    • Matsui W, Wang Q, Barber JP, et al. Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance. Cancer Res. 2008; 1(68):190-197.
    • (2008) Cancer Res , vol.1 , Issue.68 , pp. 190-197
    • Matsui, W.1    Wang, Q.2    Barber, J.P.3
  • 8
    • 69949170038 scopus 로고    scopus 로고
    • CpG CODN enhances the efficacy of rituximab in non-Hodgkin lymphoma
    • Buhe V, Guerrier T, Youinou P, Berthou C, Loisel S. CpG CODN enhances the efficacy of rituximab in non-Hodgkin lymphoma. Ann N Y Acad Sci. 2009;1173:858-864.
    • (2009) Ann N Y Acad Sci , vol.1173 , pp. 858-864
    • Buhe, V.1    Guerrier, T.2    Youinou, P.3    Berthou, C.4    Loisel, S.5
  • 9
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol. 2002;20: 709-760.
    • (2002) Annu Rev Immunol , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 10
    • 0041743207 scopus 로고    scopus 로고
    • The toll-like receptor repertoire of human B lymphocytes: Inducible and selective expression of TLR9 and TLR10 in normal and transformed cells
    • Bourke E, Bosisio D, Golay J, Polentarutti N, Mantovani A. The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells. Blood. 2003;3(102):956-963.
    • (2003) Blood , vol.3 , Issue.102 , pp. 956-963
    • Bourke, E.1    Bosisio, D.2    Golay, J.3    Polentarutti, N.4    Mantovani, A.5
  • 11
    • 53549135771 scopus 로고    scopus 로고
    • Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6
    • Cognasse F, Hamzeh-Cognasse H, Lafarge S, et al. Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6. Immunology. 2008;3(125):430-437.
    • (2008) Immunology , vol.3 , Issue.125 , pp. 430-437
    • Cognasse, F.1    Hamzeh-Cognasse, H.2    Lafarge, S.3
  • 12
    • 40449137383 scopus 로고    scopus 로고
    • CpG drives human transitional B cells to terminal differentiation and production of natural antibodies
    • Capolunghi F, Cascioli S, Giorda E, et al. CpG drives human transitional B cells to terminal differentiation and production of natural antibodies. J Immunol. 2008;2(180):800-808.
    • (2008) J Immunol , vol.2 , Issue.180 , pp. 800-808
    • Capolunghi, F.1    Cascioli, S.2    Giorda, E.3
  • 13
    • 20044371011 scopus 로고    scopus 로고
    • B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides
    • Jahrsdorfer B, Muhlenhoff L, Blackwell SE, et al. B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides. Clin Cancer Res. 2005;4(11):1490-1499.
    • (2005) Clin Cancer Res , vol.4 , Issue.11 , pp. 1490-1499
    • Jahrsdorfer, B.1    Muhlenhoff, L.2    Blackwell, S.E.3
  • 14
    • 0035155134 scopus 로고    scopus 로고
    • CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens
    • Jahrsdorfer B, Hartmann G, Racila E, et al. CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens. J Leukoc Biol. 2001;1(69):81-88.
    • (2001) J Leukoc Biol , vol.1 , Issue.69 , pp. 81-88
    • Jahrsdorfer, B.1    Hartmann, G.2    Racila, E.3
  • 15
    • 68549103458 scopus 로고    scopus 로고
    • A threshold level of TLR9 mRNA predicts cellular responsiveness to CpG-ODN in haematological and non-haematological tumour cell lines
    • Assaf A, Esteves H, Curnow SJ, Browning MJ. A threshold level of TLR9 mRNA predicts cellular responsiveness to CpG-ODN in haematological and non-haematological tumour cell lines. Cell Immunol. 2009;1(259):90-99.
    • (2009) Cell Immunol , vol.1 , Issue.259 , pp. 90-99
    • Assaf, A.1    Esteves, H.2    Curnow, S.J.3    Browning, M.J.4
  • 16
    • 36348953188 scopus 로고    scopus 로고
    • Expression of functional toll-like receptors by B-chronic lymphocytic leukemia cells
    • Grandjenette C, Kennel A, Faure GC, Bene MC, Feugier P. Expression of functional toll-like receptors by B-chronic lymphocytic leukemia cells. Haematologica. 2007;9(92):1279-1281.
    • (2007) Haematologica , vol.9 , Issue.92 , pp. 1279-1281
    • Grandjenette, C.1    Kennel, A.2    Faure, G.C.3    Bene, M.C.4    Feugier, P.5
  • 17
    • 11244280803 scopus 로고    scopus 로고
    • Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: Increased interferon-alpha/ beta-inducible gene expression, without significant toxicity
    • Friedberg JW, Kim H, McCauley M, et al. Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-alpha/ beta-inducible gene expression, without significant toxicity. Blood. 2005;2(105):489-495.
    • (2005) Blood , vol.2 , Issue.105 , pp. 489-495
    • Friedberg, J.W.1    Kim, H.2    McCauley, M.3
  • 18
    • 33748683549 scopus 로고    scopus 로고
    • Oligode-oxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma
    • Link BK, Ballas ZK, Weisdorf D, et al. Oligode-oxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma. J Immunother. 2006;5(29):558-568.
    • (2006) J Immunother , vol.5 , Issue.29 , pp. 558-568
    • Link, B.K.1    Ballas, Z.K.2    Weisdorf, D.3
  • 19
    • 4444225475 scopus 로고    scopus 로고
    • Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity
    • Hess DA, Meyerrose TE, Wirthlin L, et al. Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity. Blood. 2004;6(104):1648-1655.
    • (2004) Blood , vol.6 , Issue.104 , pp. 1648-1655
    • Hess, D.A.1    Meyerrose, T.E.2    Wirthlin, L.3
  • 20
    • 33745508017 scopus 로고    scopus 로고
    • Identification of a primitive brain-derived neural stem cell population based on aldehyde dehydrogenase activity
    • Corti S, Locatelli F, Papadimitriou D, et al. Identification of a primitive brain-derived neural stem cell population based on aldehyde dehydrogenase activity. Stem Cells. 2006;4(24):975-985.
    • (2006) Stem Cells , vol.4 , Issue.24 , pp. 975-985
    • Corti, S.1    Locatelli, F.2    Papadimitriou, D.3
  • 21
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell. 2007;5(1):555-567.
    • (2007) Cell Stem Cell , vol.5 , Issue.1 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3
  • 22
    • 65949112714 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
    • Huang EH, Hynes MJ, Zhang T, et al. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res. 2009;8(69):3382-3389.
    • (2009) Cancer Res , vol.8 , Issue.69 , pp. 3382-3389
    • Huang, E.H.1    Hynes, M.J.2    Zhang, T.3
  • 23
    • 70350247558 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer
    • Carpentino JE, Hynes MJ, Appelman HD, et al. Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer. Cancer Res. 2009;20(69): 8208-8215.
    • (2009) Cancer Res , vol.20 , Issue.69 , pp. 8208-8215
    • Carpentino, J.E.1    Hynes, M.J.2    Appelman, H.D.3
  • 24
    • 1542283717 scopus 로고    scopus 로고
    • Characterization of clonogenic multiple myeloma cells
    • Matsui W, Huff CA, Wang Q, et al. Characterization of clonogenic multiple myeloma cells. Blood. 2004;6(103):2332-2336.
    • (2004) Blood , vol.6 , Issue.103 , pp. 2332-2336
    • Matsui, W.1    Huff, C.A.2    Wang, Q.3
  • 25
    • 67651092337 scopus 로고    scopus 로고
    • Circulating clonotypic B cells in classic Hodgkin lymphoma
    • Jones RJ, Gocke CD, Kasamon YL, et al. Circulating clonotypic B cells in classic Hodgkin lymphoma. Blood. 2009;23(113):5920-5926.
    • (2009) Blood , vol.23 , Issue.113 , pp. 5920-5926
    • Jones, R.J.1    Gocke, C.D.2    Kasamon, Y.L.3
  • 26
    • 49149107236 scopus 로고    scopus 로고
    • Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy
    • Dylla SJ, Beviglia L, Park IK, et al. Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. PLoS ONE. 2008; 6(3):e2428.
    • (2008) PLoS ONE , vol.6 , Issue.3
    • Dylla, S.J.1    Beviglia, L.2    Park, I.K.3
  • 27
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;7120(444):756-760.
    • (2006) Nature , vol.7120 , Issue.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3
  • 28
    • 0026644834 scopus 로고
    • Cyclophosphamide resistance in medulloblastoma
    • Friedman HS, Colvin OM, Kaufmann SH, et al. Cyclophosphamide resistance in medulloblastoma. Cancer Res. 1992;19(52):5373-5378.
    • (1992) Cancer Res , vol.19 , Issue.52 , pp. 5373-5378
    • Friedman, H.S.1    Colvin, O.M.2    Kaufmann, S.H.3
  • 29
    • 0029004122 scopus 로고
    • Assessment of aldehyde dehydrogenase in viable cells
    • Jones RJ, Barber JP, Vala MS, et al. Assessment of aldehyde dehydrogenase in viable cells. Blood. 1995;10(85):2742-2746.
    • (1995) Blood , vol.10 , Issue.85 , pp. 2742-2746
    • Jones, R.J.1    Barber, J.P.2    Vala, M.S.3
  • 30
    • 0034629129 scopus 로고    scopus 로고
    • Hematopoietic stem cell quiescence maintained by p21cip1/ waf1
    • Cheng T, Rodrigues N, Shen H, et al. Hematopoietic stem cell quiescence maintained by p21cip1/ waf1. Science. 2000;5459(287):1804-1808.
    • (2000) Science , vol.5459 , Issue.287 , pp. 1804-1808
    • Cheng, T.1    Rodrigues, N.2    Shen, H.3
  • 31
    • 11144353781 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of Tcell help
    • Poeck H, Wagner M, Battiany J, et al. Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of Tcell help. Blood. 2004;8(103):3058-3064.
    • (2004) Blood , vol.8 , Issue.103 , pp. 3058-3064
    • Poeck, H.1    Wagner, M.2    Battiany, J.3
  • 32
    • 0030950523 scopus 로고    scopus 로고
    • Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation
    • Lin Y, Wong K, Calame K. Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. Science. 1997;5312(276):596-599.
    • (1997) Science , vol.5312 , Issue.276 , pp. 596-599
    • Lin, Y.1    Wong, K.2    Calame, K.3
  • 33
    • 3142658576 scopus 로고    scopus 로고
    • XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
    • Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, et al. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity. 2004;1(21):81-93.
    • (2004) Immunity , vol.1 , Issue.21 , pp. 81-93
    • Shaffer, A.L.1    Shapiro-Shelef, M.2    Iwakoshi, N.N.3
  • 34
    • 0024755681 scopus 로고
    • B lymphocytes express and lose syndecan at specific stages of differentiation
    • Sanderson RD, Lalor P, Bernfield M. B lymphocytes express and lose syndecan at specific stages of differentiation. Cell Regul. 1989;1(1): 27-35.
    • (1989) Cell Regul , vol.1 , Issue.1 , pp. 27-35
    • Sanderson, R.D.1    Lalor, P.2    Bernfield, M.3
  • 35
    • 0037385313 scopus 로고    scopus 로고
    • Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
    • Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol. 2003;4(4):321-329.
    • (2003) Nat Immunol , vol.4 , Issue.4 , pp. 321-329
    • Iwakoshi, N.N.1    Lee, A.H.2    Vallabhajosyula, P.3    Otipoby, K.L.4    Rajewsky, K.5    Glimcher, L.H.6
  • 36
    • 70450227260 scopus 로고    scopus 로고
    • Proteasome inhibitors in the treatment of multiple myeloma
    • Shah JJ, Orlowski RZ. Proteasome inhibitors in the treatment of multiple myeloma. Leukemia. 2009;11(23):1964-1979.
    • (2009) Leukemia , vol.11 , Issue.23 , pp. 1964-1979
    • Shah, J.J.1    Orlowski, R.Z.2
  • 37
    • 68449096176 scopus 로고    scopus 로고
    • Dysregulation of unfolded protein response partially underlies proapoptotic activity of bortezomib in multiple myeloma cells
    • Dong H, Chen L, Chen X, et al. Dysregulation of unfolded protein response partially underlies proapoptotic activity of bortezomib in multiple myeloma cells. Leuk Lymphoma. 2009;6(50):974-984.
    • (2009) Leuk Lymphoma , vol.6 , Issue.50 , pp. 974-984
    • Dong, H.1    Chen, L.2    Chen, X.3
  • 38
    • 33744539521 scopus 로고    scopus 로고
    • Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
    • Obeng EA, Carlson LM, Gutman DM, Harrington WJ Jr, Lee KP, Boise LH. Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells. Blood. 2006;12(107): 4907-4916.
    • (2006) Blood , vol.12 , Issue.107 , pp. 4907-4916
    • Obeng, E.A.1    Carlson, L.M.2    Gutman, D.M.3    Harrington Jr., W.J.4    Lee, K.P.5    Boise, L.H.6
  • 39
    • 0031671642 scopus 로고    scopus 로고
    • A newly discovered class of human hematopoietic cells with SCID-repopulating activity
    • Bhatia M, Bonnet D, Murdoch B, Gan OI, Dick JE. A newly discovered class of human hematopoietic cells with SCID-repopulating activity. Nat Med. 1998;9(4):1038-1045.
    • (1998) Nat Med , vol.9 , Issue.4 , pp. 1038-1045
    • Bhatia, M.1    Bonnet, D.2    Murdoch, B.3    Gan, O.I.4    Dick, J.E.5
  • 40
    • 16144365969 scopus 로고    scopus 로고
    • Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
    • Larochelle A, Vormoor J, Hanenberg H, et al. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy. Nat Med. 1996;12(2):1329-1337.
    • (1996) Nat Med , vol.12 , Issue.2 , pp. 1329-1337
    • Larochelle, A.1    Vormoor, J.2    Hanenberg, H.3
  • 41
    • 0344735881 scopus 로고    scopus 로고
    • Cancerous stem cells can arise from pediatric brain tumors
    • Hemmati HD, Nakano I, Lazareff JA, et al. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci U S A. 2003;25(100): 15178-15183.
    • (2003) Proc Natl Acad Sci U S A , vol.25 , Issue.100 , pp. 15178-15183
    • Hemmati, H.D.1    Nakano, I.2    Lazareff, J.A.3
  • 42
    • 57749091753 scopus 로고    scopus 로고
    • Cancer stem cells are enriched in the side population cells in a mouse model of glioma
    • Harris MA, Yang H, Low BE, et al. Cancer stem cells are enriched in the side population cells in a mouse model of glioma. Cancer Res. 2008; 24(68):10051-10059.
    • (2008) Cancer Res , vol.24 , Issue.68 , pp. 10051-10059
    • Harris, M.A.1    Yang, H.2    Low, B.E.3
  • 44
    • 42049110004 scopus 로고    scopus 로고
    • Noxa mediates bortezomib induced apoptosis in both sensitive and intrinsically resistant mantle cell lymphoma cells and this effect is independent of constitutive activity of the AKT and NF-kappaB pathways
    • Rizzatti EG, Mora-Jensen H, Weniger MA, et al. Noxa mediates bortezomib induced apoptosis in both sensitive and intrinsically resistant mantle cell lymphoma cells and this effect is independent of constitutive activity of the AKT and NF-kappaB pathways. Leuk Lymphoma. 2008; 4(49):798-808.
    • (2008) Leuk Lymphoma , vol.4 , Issue.49 , pp. 798-808
    • Rizzatti, E.G.1    Mora-Jensen, H.2    Weniger, M.A.3
  • 45
    • 61649094981 scopus 로고    scopus 로고
    • Bortezomib in patients with relapsed or refractory mantle cell lymphoma: Updated time-to-event analyses of the multicenter phase 2 PINNACLE study
    • Goy A, Bernstein SH, Kahl BS, et al. Bortezomib in patients with relapsed or refractory mantle cell lymphoma: updated time-to-event analyses of the multicenter phase 2 PINNACLE study. Ann Oncol. 2009;3(20):520-525.
    • (2009) Ann Oncol , vol.3 , Issue.20 , pp. 520-525
    • Goy, A.1    Bernstein, S.H.2    Kahl, B.S.3
  • 46
    • 61849128387 scopus 로고    scopus 로고
    • Patients with chemotherapy-refractory mantle cell lymphoma experience high response rates and identical progression-free survivals compared with patients with relapsed disease following treatment with single agent bortezomib: Results of a multicentre Phase 2 clinical trial
    • O'Connor OA, Moskowitz C, Portlock C, et al. Patients with chemotherapy-refractory mantle cell lymphoma experience high response rates and identical progression-free survivals compared with patients with relapsed disease following treatment with single agent bortezomib: results of a multicentre Phase 2 clinical trial. Br J Haematol. 2009;1(145):34-39.
    • (2009) Br J Haematol , vol.1 , Issue.145 , pp. 34-39
    • O'Connor, O.A.1    Moskowitz, C.2    Portlock, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.