-
1
-
-
33645526144
-
Cancer statistics, 2006
-
Jemal, A. et al. Cancer statistics, 2006. CA Cancer J. Clin. 56, 106-130 (2006).
-
(2006)
CA Cancer J. Clin
, vol.56
, pp. 106-130
-
-
Jemal, A.1
-
2
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
Schiller, J. H. et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N. Engl. J. Med. 346, 92-98 (2002).
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 92-98
-
-
Schiller, J.H.1
-
3
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch, T. J. et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 350, 2129-2139 (2004).
-
(2004)
N. Engl. J. Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
-
4
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez, J. G. et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304, 1497-1500 (2004).
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
-
5
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker, B. J. et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N. Engl. J. Med. 344, 1031-1037 (2001).
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
-
6
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao, W. et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc. Natl Acad. Sci. USA 101, 13306-13311 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
-
7
-
-
6344262173
-
An alternative transcript derived from the Trio locus encodes a guanosine nucleotide exchange factor with mouse cell-transforming potential
-
Yoshizuka, N. et al. An alternative transcript derived from the Trio locus encodes a guanosine nucleotide exchange factor with mouse cell-transforming potential. J. Biol. Chem. 279, 43998-44004 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 43998-44004
-
-
Yoshizuka, N.1
-
8
-
-
33947663549
-
Transforming activity of purinergic receptor P2Y, G-protein coupled, 2 revealed by retroviral expression screening
-
Hatanaka, H. et al. Transforming activity of purinergic receptor P2Y, G-protein coupled, 2 revealed by retroviral expression screening. Biochem. Biophys. Res. Commun. 356, 723-726 (2007).
-
(2007)
Biochem. Biophys. Res. Commun
, vol.356
, pp. 723-726
-
-
Hatanaka, H.1
-
9
-
-
33845208243
-
Identification of a constitutively active mutant of JAK3 by retroviral expression screening
-
Choi, Y. L. et al. Identification of a constitutively active mutant of JAK3 by retroviral expression screening. Leuk. Res. 31, 203-209 (2007).
-
(2007)
Leuk. Res
, vol.31
, pp. 203-209
-
-
Choi, Y.L.1
-
10
-
-
27744570032
-
Transforming activity of the lymphotoxin-β receptor revealed by expression screening
-
Fujiwara, S. et al. Transforming activity of the lymphotoxin-β receptor revealed by expression screening. Biochem. Biophys. Res. Commun. 338, 1256-1262 (2005).
-
(2005)
Biochem. Biophys. Res. Commun
, vol.338
, pp. 1256-1262
-
-
Fujiwara, S.1
-
11
-
-
33748620045
-
Human EML4, a novel member of the EMAP family, is essential for microtubule formation
-
Pollmann, M. et al. Human EML4, a novel member of the EMAP family, is essential for microtubule formation. Exp. Cell Res. 312, 3241-3251 (2006).
-
(2006)
Exp. Cell Res
, vol.312
, pp. 3241-3251
-
-
Pollmann, M.1
-
12
-
-
0037059752
-
The human EMAP-like protein-70 (ELP70) is a microtubule destabilizer that localizes to the mitotic apparatus
-
Eichenmuller, B., Everley, P., Palange, J., Lepley, D. & Suprenant, K. A. The human EMAP-like protein-70 (ELP70) is a microtubule destabilizer that localizes to the mitotic apparatus. J. Biol. Chem. 277, 1301-1309 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 1301-1309
-
-
Eichenmuller, B.1
Everley, P.2
Palange, J.3
Lepley, D.4
Suprenant, K.A.5
-
13
-
-
0033133919
-
The WD repeat: A common architecture for diverse functions
-
Smith, T. F., Gaitatzes, C., Saxena, K. & Neer, E. J. The WD repeat: a common architecture for diverse functions. Trends Biochem. Sci. 24, 181-185 (1999).
-
(1999)
Trends Biochem. Sci
, vol.24
, pp. 181-185
-
-
Smith, T.F.1
Gaitatzes, C.2
Saxena, K.3
Neer, E.J.4
-
14
-
-
0028198206
-
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
-
Morris, S. W. et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 263, 1281-1284 (1994).
-
(1994)
Science
, vol.263
, pp. 1281-1284
-
-
Morris, S.W.1
-
15
-
-
0028275645
-
Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3
-
Shiota, M. et al. Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3. Oncogene 9, 1567-1574 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 1567-1574
-
-
Shiota, M.1
-
16
-
-
2342635959
-
Anaplastic lymphoma kinase proteins in growth control and cancer
-
Pulford, K., Morris, S. W. & Turturro, F. Anaplastic lymphoma kinase proteins in growth control and cancer. J. Cell. Physiol. 199, 330-358 (2004).
-
(2004)
J. Cell. Physiol
, vol.199
, pp. 330-358
-
-
Pulford, K.1
Morris, S.W.2
Turturro, F.3
-
17
-
-
33846110366
-
Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK
-
Galkin, A. V. et al. Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK. Proc. Natl Acad. Sci. USA 104, 270-275 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 270-275
-
-
Galkin, A.V.1
-
18
-
-
20444399542
-
Unique substrate specificity of anaplastic lymphoma kinase (ALK): Development of phosphoacceptor peptides for the assay of ALK activity
-
Donella-Deana, A. et al. Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity. Biochemistry 44, 8533-8542 (2005).
-
(2005)
Biochemistry
, vol.44
, pp. 8533-8542
-
-
Donella-Deana, A.1
-
19
-
-
0036111194
-
XL chimeric gene with transforming activity
-
XL chimeric gene with transforming activity. Am. J. Pathol. 160, 1487-1494 (2002).
-
(2002)
Am. J. Pathol
, vol.160
, pp. 1487-1494
-
-
Hernandez, L.1
-
20
-
-
0022274007
-
-
Palacious, R. & Steinmetz, M. IL-3 dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo. Cell 41, 727-734 (1985).
-
Palacious, R. & Steinmetz, M. IL-3 dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo. Cell 41, 727-734 (1985).
-
-
-
-
21
-
-
0034923241
-
Molecular detection of Mycobacterium tuberculosis: Impact on patient care
-
Kaul, K. L. Molecular detection of Mycobacterium tuberculosis: impact on patient care. Clin. Chem. 47, 1553-1558 (2001).
-
(2001)
Clin. Chem
, vol.47
, pp. 1553-1558
-
-
Kaul, K.L.1
-
22
-
-
27944485366
-
Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3
-
Marzec, M. et al. Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3. Lab. Invest. 85, 1544-1554 (2005).
-
(2005)
Lab. Invest
, vol.85
, pp. 1544-1554
-
-
Marzec, M.1
-
23
-
-
32344432487
-
Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinase
-
Li, R. et al. Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinase. J. Med. Chem. 49, 1006-1015 (2006).
-
(2006)
J. Med. Chem
, vol.49
, pp. 1006-1015
-
-
Li, R.1
-
24
-
-
15844389026
-
JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells
-
Watanabe, S., Itoh, T. & Arai, K. JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells. J. Biol. Chem. 271, 12681-12686 (1996).
-
(1996)
J. Biol. Chem
, vol.271
, pp. 12681-12686
-
-
Watanabe, S.1
Itoh, T.2
Arai, K.3
-
25
-
-
0035839867
-
Translocations involving anaplastic lymphoma kinase (ALK)
-
Duyster, J., Bai, R. Y. & Morris, S. W. Translocations involving anaplastic lymphoma kinase (ALK). Oncogene 20, 5623-5637 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 5623-5637
-
-
Duyster, J.1
Bai, R.Y.2
Morris, S.W.3
-
26
-
-
0029913455
-
Applications of retrovirus-mediated expression cloning
-
Onishi, M. et al. Applications of retrovirus-mediated expression cloning. Exp. Hematol. 24, 324-329 (1996).
-
(1996)
Exp. Hematol
, vol.24
, pp. 324-329
-
-
Onishi, M.1
-
27
-
-
18044403477
-
Sak serine/threonine kinase acts as an effector of Tec tyrosine kinase
-
Yamashita, Y. et al. Sak serine/threonine kinase acts as an effector of Tec tyrosine kinase. J. Biol. Chem. 276, 39012-39020 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 39012-39020
-
-
Yamashita, Y.1
|