-
1
-
-
0035393595
-
Rituximab inactivates signal transducer and activation of transcription 3 (STAT3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of Bcl-2 and sensitization to cytotoxic drugs
-
Alas S, Bonavida B. (2001). Rituximab inactivates signal transducer and activation of transcription 3 (STAT3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of Bcl-2 and sensitization to cytotoxic drugs. Cancer Res 61:5137-5144.
-
(2001)
Cancer Res
, vol.61
, pp. 5137-5144
-
-
Alas, S.1
Bonavida, B.2
-
2
-
-
0029880345
-
Incidence of homogeneously staining regions in non-Hodgkin lymphomas
-
Arranz E, Robledo M, Martfnez B, Gallego J, Remain A, Rivas C et al. (1996). Incidence of homogeneously staining regions in non-Hodgkin lymphomas. Cancer Genet Cytogenet 87:1-3.
-
(1996)
Cancer Genet Cytogenet
, vol.87
, pp. 1-3
-
-
Arranz, E.1
Robledo, M.2
Martfnez, B.3
Gallego, J.4
Remain, A.5
Rivas, C.6
-
3
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC. (2002). The phosphoinositide 3-kinase pathway. Science 296:1655-1657.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
4
-
-
0001457668
-
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
-
Cheng JQ, Ruggeri B, Klein WM, Sonoda G, Altomare DA, Watson DK et al. (1996). Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Sci USA 93:3636-3641.
-
(1996)
Sci USA
, vol.93
, pp. 3636-3641
-
-
Cheng, J.Q.1
Ruggeri, B.2
Klein, W.M.3
Sonoda, G.4
Altomare, D.A.5
Watson, D.K.6
-
5
-
-
27844598284
-
The Akt/PKB pathway:molecular target for cancer drug discovery
-
Cheng JQ, Lindsley CW, Cheng GZ, Yang H, Nicosia SV. (2005). The Akt/PKB pathway:molecular target for cancer drug discovery. Oncogene 24:7482-7492.
-
(2005)
Oncogene
, vol.24
, pp. 7482-7492
-
-
Cheng, J.Q.1
Lindsley, C.W.2
Cheng, G.Z.3
Yang, H.4
Nicosia, S.V.5
-
6
-
-
4344664011
-
A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells
-
Cuni S, Perez-Aciego P, Perez-Chacon G, Vargas JA, Sanchez A, Martin-Saavedra FM et al. (2004). A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells. Leukemia 18:139 1-1400.
-
(2004)
Leukemia
, vol.18
, Issue.139
, pp. 1-1400
-
-
Cuni, S.1
Perez-Aciego, P.2
Perez-Chacon, G.3
Vargas, J.A.4
Sanchez, A.5
Martin-Saavedra, F.M.6
-
7
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta SR, Brunet A, Greenberg ME. (1999). Cellular survival: a play in three Akts. Genes Dev 13:2905-2927.
-
(1999)
Genes Dev
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
8
-
-
0034681264
-
The multiple roles of PTEN in tumor suppression
-
Di Cristofano A, Pandolfi PP. (2000). The multiple roles of PTEN in tumor suppression. Cell 100:387-390.
-
(2000)
Cell
, vol.100
, pp. 387-390
-
-
Di Cristofano, A.1
Pandolfi, P.P.2
-
9
-
-
27944494840
-
Isolation and Characterization of the B-Cell Marker CD20
-
Ernst JA, Li H, Kim HS, Nakamura GR, Yansura DG, Vandlen RL. (2005). Isolation and Characterization of the B-Cell Marker CD20. Biochemistry 44:15150-15158.
-
(2005)
Biochemistry
, vol.44
, pp. 15150-15158
-
-
Ernst, J.A.1
Li, H.2
Kim, H.S.3
Nakamura, G.R.4
Yansura, D.G.5
Vandlen, R.L.6
-
10
-
-
33645524134
-
The phosphoinositide 3-kinase/Akt1/Par-4 axis:a cancer-selective therapeutic target
-
Goswami A, Ranganathan P, Rangnekar VM. (2006). The phosphoinositide 3-kinase/Akt1/Par-4 axis:a cancer-selective therapeutic target. Cancer Res 66:2889-2892.
-
(2006)
Cancer Res
, vol.66
, pp. 2889-2892
-
-
Goswami, A.1
Ranganathan, P.2
Rangnekar, V.M.3
-
11
-
-
33744742933
-
Common genetic variation at PTEN and risk of sporadic breast and prostate cancer
-
Haiman CA, Stram DO, Cheng I, Giorgi EE, Pooler L, Penney K et al. (2006). Common genetic variation at PTEN and risk of sporadic breast and prostate cancer. Cancer Epidemiol Biomarkers Prev 15:1 021-1025.
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, Issue.1
, pp. 021-1025
-
-
Haiman, C.A.1
Stram, D.O.2
Cheng, I.3
Giorgi, E.E.4
Pooler, L.5
Penney, K.6
-
12
-
-
0034326803
-
Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin
-
Hayakawa J, Ohmichi M, Kurachi H, Kanda Y, Hisamoto K, Nishio Y et al. (2000). Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin. Cancer Res 60: 5988-5994.
-
(2000)
Cancer Res
, vol.60
, pp. 5988-5994
-
-
Hayakawa, J.1
Ohmichi, M.2
Kurachi, H.3
Kanda, Y.4
Hisamoto, K.5
Nishio, Y.6
-
13
-
-
16444363534
-
Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkin's lymphoma:im plications in chemosensitization and therapeutic intervention
-
Jazirehi AR, Bonavida B. (2005). Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkin's lymphoma:im plications in chemosensitization and therapeutic intervention. Oncogene 24:21 21-2143.
-
(2005)
Oncogene
, vol.24
, Issue.21
, pp. 21-2143
-
-
Jazirehi, A.R.1
Bonavida, B.2
-
14
-
-
11244254238
-
-
Jazirehi AR, Huerta-Yepez S, Cheng G, Bonavida B. (2005). Rituximab (chimeric anti-CD20 monoclonal antibody) inhibits the constitutive nuclear factor-\{kappa\}B signaling pathway in non-Hodgkin's lymphoma B-cell lines:role in sensitization to chemo. Cancer Res 65:264-276.
-
Jazirehi AR, Huerta-Yepez S, Cheng G, Bonavida B. (2005). Rituximab (chimeric anti-CD20 monoclonal antibody) inhibits the constitutive nuclear factor-\{kappa\}B signaling pathway in non-Hodgkin's lymphoma B-cell lines:role in sensitization to chemo. Cancer Res 65:264-276.
-
-
-
-
15
-
-
33847014608
-
Development of rituximab-resistant lymphoma clones with altered cell signaling and cross-resistance to chemotherapy
-
Jazirehi AR, Vega MI, Bonavida B. (2007). Development of rituximab-resistant lymphoma clones with altered cell signaling and cross-resistance to chemotherapy. Cancer Res 67:1270-1281.
-
(2007)
Cancer Res
, vol.67
, pp. 1270-1281
-
-
Jazirehi, A.R.1
Vega, M.I.2
Bonavida, B.3
-
16
-
-
4944264724
-
Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab
-
Jazirehi AR, Vega MI, Chatterjee D, Goodglick L, Bonavida B. (2004). Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab. Cancer Res 64:71 17-7126.
-
(2004)
Cancer Res
, vol.64
, Issue.71
, pp. 17-7126
-
-
Jazirehi, A.R.1
Vega, M.I.2
Chatterjee, D.3
Goodglick, L.4
Bonavida, B.5
-
17
-
-
23444461754
-
PTEN expression in non-small-cell lung cancer:evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration
-
Marsit CJ, Zheng S, Aldape K, Hinds PW, Nelson HH, Wiencke JK et al. (2005). PTEN expression in non-small-cell lung cancer:evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration. Hum Pathol 36: 768-776.
-
(2005)
Hum Pathol
, vol.36
, pp. 768-776
-
-
Marsit, C.J.1
Zheng, S.2
Aldape, K.3
Hinds, P.W.4
Nelson, H.H.5
Wiencke, J.K.6
-
18
-
-
13844273087
-
PI3K-Akt pathway: Its functions and alterations in human cancer
-
Osaki M, Oshimura M, Ito H. (2004). PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis 9: 667-676.
-
(2004)
Apoptosis
, vol.9
, pp. 667-676
-
-
Osaki, M.1
Oshimura, M.2
Ito, H.3
-
19
-
-
0033517189
-
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
-
Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. (1999). NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 401:82-85.
-
(1999)
Nature
, vol.401
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
20
-
-
22244478639
-
LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway
-
Poh TW, Pervaiz S. (2005). LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway. Cancer Res 65:6264-6274.
-
(2005)
Cancer Res
, vol.65
, pp. 6264-6274
-
-
Poh, T.W.1
Pervaiz, S.2
-
21
-
-
0032804575
-
Epigenetic Mechanisms for Progression of Prostate Cancer
-
Review
-
Rennie PS, Nelson CC. (1998). Epigenetic Mechanisms for Progression of Prostate Cancer. Cancer Metastasis Rev 17: 401-409 Review.
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 401-409
-
-
Rennie, P.S.1
Nelson, C.C.2
-
22
-
-
33646581352
-
Overview of non-Hodgkin's lymphoma
-
Rogers BB. (2006). Overview of non-Hodgkin's lymphoma. Semin Oncol Nurs 22:67-72.
-
(2006)
Semin Oncol Nurs
, vol.22
, pp. 67-72
-
-
Rogers, B.B.1
-
23
-
-
0032030699
-
Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies
-
Shan D, Ledbetter JA, Press OW. (1998). Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies. Blood 91:1644-1652.
-
(1998)
Blood
, vol.91
, pp. 1644-1652
-
-
Shan, D.1
Ledbetter, J.A.2
Press, O.W.3
-
24
-
-
27644484777
-
BMP-2 prevents apoptosis of the N1511 chondrocytic cell line through PI3K/Akt-mediated NF-kappaB activation
-
Sugimori K, Matsui K, Motomura H, Tokoro T, Wang J, Higa S et al. (2005). BMP-2 prevents apoptosis of the N1511 chondrocytic cell line through PI3K/Akt-mediated NF-kappaB activation. J Bone Miner Metab 23:411-419.
-
(2005)
J Bone Miner Metab
, vol.23
, pp. 411-419
-
-
Sugimori, K.1
Matsui, K.2
Motomura, H.3
Tokoro, T.4
Wang, J.5
Higa, S.6
-
25
-
-
0034520342
-
Enhanced cell killing by overexpression of dominant-negative phosphatidylinositol 3-kinase subunit, Deltap85, following genotoxic stresses
-
Tachiiri S, Sasai K, Oya N, Hiraoka M. (2000). Enhanced cell killing by overexpression of dominant-negative phosphatidylinositol 3-kinase subunit, Deltap85, following genotoxic stresses. Jpn J Cancer Res 91:1314-1318.
-
(2000)
Jpn J Cancer Res
, vol.91
, pp. 1314-1318
-
-
Tachiiri, S.1
Sasai, K.2
Oya, N.3
Hiraoka, M.4
-
26
-
-
33646253672
-
Akt signaling and cancer: Surviving but not moving on
-
Toker A, Yoeli-Lerner M. (2006). Akt signaling and cancer: surviving but not moving on. Cancer Res 66:3963-3966.
-
(2006)
Cancer Res
, vol.66
, pp. 3963-3966
-
-
Toker, A.1
Yoeli-Lerner, M.2
-
27
-
-
3042801429
-
Inhibition of phosphatidylinositol 3′-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway
-
Uddin S, Hussain A, Al-Hussein K, Platanias LC, Bhatiaa KG. (2004). Inhibition of phosphatidylinositol 3′-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway. Biochem Biophys Res Commun 320:93 2-938.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, Issue.93
, pp. 2-938
-
-
Uddin, S.1
Hussain, A.2
Al-Hussein, K.3
Platanias, L.C.4
Bhatiaa, K.G.5
-
28
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco I, Sawyers CL. (2002). The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2: 489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
29
-
-
1642430931
-
Resistance to antineoplastic therapy. The oncogenic tyrosine kinase-Bcl-x(L) axis
-
Weintraub SJ, Manson SR, Deverman BE. (2004). Resistance to antineoplastic therapy. The oncogenic tyrosine kinase-Bcl-x(L) axis. Cancer Cell 5:3-4.
-
(2004)
Cancer Cell
, vol.5
, pp. 3-4
-
-
Weintraub, S.J.1
Manson, S.R.2
Deverman, B.E.3
-
30
-
-
2442596885
-
Phosphoinositide 3-kinases as targets for therapeutic intervention
-
Wetzker R, Rommel C. (2004). Phosphoinositide 3-kinases as targets for therapeutic intervention. Curr Pharm Des 10: 1915-1922.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 1915-1922
-
-
Wetzker, R.1
Rommel, C.2
-
31
-
-
0029927494
-
Predominant expression of the long isoform of Bcl-x (Bcl-xL) in human lymphomas
-
Xerri L, Parc P, Brousset P, Schlaifer D, Hassoun J, Reed JC et al. (1996). Predominant expression of the long isoform of Bcl-x (Bcl-xL) in human lymphomas. Br J Haematol 92: 900-906.
-
(1996)
Br J Haematol
, vol.92
, pp. 900-906
-
-
Xerri, L.1
Parc, P.2
Brousset, P.3
Schlaifer, D.4
Hassoun, J.5
Reed, J.C.6
-
32
-
-
33646098688
-
Morphine promotes Jurkat cell apoptosis through pro-apoptotic FADD/P53 and anti-apoptotic PI3K/Akt/NF-kappaB pathways
-
Yin D, Woodruff M, Zhang Y, Whaley S, Miao J, Ferslew K et al. (2006). Morphine promotes Jurkat cell apoptosis through pro-apoptotic FADD/P53 and anti-apoptotic PI3K/Akt/NF-kappaB pathways. J Neuroimmunol 174: 101-107.
-
(2006)
J Neuroimmunol
, vol.174
, pp. 101-107
-
-
Yin, D.1
Woodruff, M.2
Zhang, Y.3
Whaley, S.4
Miao, J.5
Ferslew, K.6
-
33
-
-
9144220128
-
Prognostic significance of bcl-xL gene expression and apoptotic cell counts in follicular lymphoma
-
Zhao WL, Daneshpouy ME, Mounier N, Briere J, Leboeuf C, Plassa LF et al. (2004). Prognostic significance of bcl-xL gene expression and apoptotic cell counts in follicular lymphoma. Blood 103:695-697.
-
(2004)
Blood
, vol.103
, pp. 695-697
-
-
Zhao, W.L.1
Daneshpouy, M.E.2
Mounier, N.3
Briere, J.4
Leboeuf, C.5
Plassa, L.F.6
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