Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

Nature

Volumn 416, Issue 6876, 2002, Pages 94-99

  Reif, Karin ^a   Ekland, Eric H ^a   Ohl, Lars ^b   Nakano, Hideki ^c   Lipp, Martin ^d   Förster, Reinhold ^b   Cyster, Jason G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; GENES; HEMODYNAMICS;

CHEMOATTRACTANTS;

ANTIGENS;

CHEMOATTRACTANT; CHEMOKINE; CHEMOKINE RECEPTOR CCL19; CHEMOKINE RECEPTOR CCL21; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCL13; CHEMOKINE RECEPTOR CXCR5; UNCLASSIFIED DRUG;

ANTIBODY; BIOCHEMISTRY;

ANIMAL CELL; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL INTERACTION; CELLULAR DISTRIBUTION; FEMALE; GENE OVEREXPRESSION; GENE TRANSFER; HELPER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS; B-LYMPHOCYTES; CELL MOVEMENT; CHEMOKINES, CC; CLONING, MOLECULAR; FLOW CYTOMETRY; HUMANS; LYMPHOID TISSUE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; MURAMIDASE; RECEPTORS, CHEMOKINE; RECEPTORS, CYTOKINE;

ANIMALIA; UNIDENTIFIED RETROVIRUS;

EID: 0037034880     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/416094a     Document Type: Article

References (30)

1. Memory B Cells in T Cell-dependent antibody responses colonize the splenic marginal zones
2. Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate
3. Visualization of specific B and T lymphoccyte interactions in the lymph node
4. Chemokines and cell migration in secondary lymphoid organs
5. Chemokines: A new classification system and their role in immunity
6. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
7. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization
8. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
9. Self tolerance in the B cell repertoire
10. Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse
11. Gene duplications at the chemokine locas on mouse chromosome 4: Multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation
12. The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes
13. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
14. A chemotine driven positive feedbackloop organizes lymphoid follicles
15. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism
16. Autoimmunity as a consequence of retrovirus-mediated expression of C- FLIP in lymphocytes
17. Differential expression of CCR7 on Th1 and Th2 cells: Importance in control of T cell localization and delivery of help for antibody responses in vivo
18. Integrating conflicting chemotactic signals. The role of memory in leukocyte navigation
19. Epstein-Barr virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts qnaive T cells and activated B cells
20. The CC chemokine receptor-7 ligands 6Ckine and macrophage inflammatory protein-3 beta are potent chemoattractants for in vitro- and in vivo-derived dendritic cells
21. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
22. Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: Localization to the T-B interface of the splenic follicle
23. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3α, MIP-3β, and secondary lymphoid organ chemokine
24. Control of cell migration during Caenorhabditis elegans development
25. Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes
26. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1
27. The pCL vector system: Rapid production of helper-free, high-titer, recombinant retroviruses
28. Production of high-titer helper-free retroviruses by transient transfection
29. A coordinated change in chemokine responsiveness guides plasma cell movements
30. Spontaneous follicular exclusion of SHPI-deficient B cells is conditional on the presence of competitor wild-type B cells