The miRNA-17 ∼ 92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation

Leukemia

Volumn 26, Issue 5, 2012, Pages 1064-1072

  Rao, E ^a,b,c   Jiang, C ^a   Ji, M ^a   Huang, X ^a   Iqbal, J ^a   Lenz, G ^d,e   Wright, G ^e   Staudt, L M ^e   Zhao, Y ^b   McKeithan, T W ^a   Chan, W C ^a   Fu, K ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b INSTITUTE OF ZOOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

mantle cell lymphoma; MiR 17B92 cluster; PHLPP2; PI3K AKT pathway; PTEN

Indexed keywords

BIM PROTEIN; MICRORNA; PH DOMAIN AND LEUCINERICH REPEAT PROTEIN PHOSPHATASE 2; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CANCER PATIENT; CANCER SURVIVAL; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MANTLE CELL LYMPHOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; XENOGRAFT;

EID: 84860755726     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.305     Document Type: Article

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