Epigenetic determinants of resistance to etoposide regulation of Bcl- x(L) and Bax by tumor microenvironmental factors

Journal of the National Cancer Institute

Volumn 92, Issue 1, 2000, Pages 18-23

  Taylor, Sian T ^b   Hickman, John A ^b   Dive, Caroline ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BETA1 INTEGRIN; CAPSAICIN; CD40 ANTIGEN; ETOPOSIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 4; PROTEIN BAX; PROTEIN BCL X; VASCULAR CELL ADHESION MOLECULE 1;

APOPTOSIS; ARTICLE; B CELL LYMPHOMA; CANCER CHEMOTHERAPY; DRUG SENSITIVITY; GENE ACTIVITY; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; WESTERN BLOTTING;

EID: 0034606657     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/92.1.18     Document Type: Article

References (24)

1. Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 1998;396:643-9.
2. Drug resistance in the treatment of cancer. In: Pinedo H, Giaccone G, editors. Cambridge (U.K.): Cambridge University Press; 1998.
3. Dive C, Hickman JA. Drug target interactions: only the first step in the commitment to a programmed cell death? Br J Cancer 1991;64:192-6.
4. Raff MC. Social controls on cell survival and cell death. Nature 1992;356: 397-400.
5. Reed JC. Double identity for proteins of the Bcl-2 family. Nature 1997; 387:773-6.
6. Del Peso L, Gonzalez-Garcia M, Page C, Herrara R, Nunez G. Interleukin-3 induced phosphorylation of Bad through protein kinase Akt. Science 1997;278:687-9.
7. Rohatiner A, Lister TA. Follicular lymphoma. In: Canellos G, Lister TA, Sklar J, editors. The lymphomas. Chap. 19. Philadelphia (PA): Saunders; 1998. p. 371-87.
8. Johnson PW, Rohatiner AZ, Whelan JS, Price CG, Love S, Lim J, et al. Patterns of survival in patients with recurrent follicular lymphoma: a 20 year study from a single center. J Clin Oncol 1995;13:140-7.
9. MacLennan IC. Germinal centers. Annu Rev Immunol 1994;12:117-39.
10. Thorbeck GJ, Amin AR, Tsiaghe VK. Biology of germinal centers in lymphoid tissue. FASEB J 1994;8:832-40.
11. Clark EA, Ledbetter JA. How B and T cells talk to each other. Nature 1994;367:425-8.
12. Walker A, Taylor ST, Hickman JA, Dive C. Germinal center-derived signals act with Bcl-2 to decrease apoptotic cell death and increase clonogenicity of drug-treated human B lymphoma cells. Cancer Res 1997;57: 1939-45.
13. Gregory CD, Dive C, Henderson S, Smith CA, Williams GT, Gordon J, et al. Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis. Nature 1991;349:612-4.
14. Harlow E, Lane D. Immunoblotting, In: Antibodies: a laboratory manual. Chap. 12. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory; 1998. p. 471-511.
15. Hsu YT, Youle RJ. Nonionic detergents induce dimerisation among members of the Bcl-2 family. J Biol Chem 1997;272:13829-934.
16. Berberich I, Shu GL, Clark EA. Cross-linking CD40 on B-cells rapidly activates nuclear factor-kappa-B. J Immunol 1994;153:4357-66.
17. Singh S, Natarajan K, Aggarwal BB. Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is a potent inhibitor of nuclear transcription factor-κB activation by diverse agents. J Immunol 1996;157:4412-20.
18. Griffiths GJ, Dubrez L, Morgan CP, Jones NA, Whitehouse J, Corfe BM, et al. Cell-damage induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis. J Cell Biol 1999;144: 903-14.
19. Sumimoto SI, Heike T, Kanazashi S, Shintaku N, Jung EY, Hata D, et al. Involvement of LFA-1 intracellular adhesion molecule-1-dependent cell adhesion in CD40 mediated inhibition of human B lymphoma cell death induced by surface IgM crosslinking. J Immunol 1994;153:2488-96.
20. Wang Z, Karras JG, Howard RG, Rothstein TL. Induction of Bcl-X by CD40 engagement rescues slg-induced apoptosis in murine B-cells. J Immunol 1995;155:3722-5.
21. L in CD40-mediated rescue from anti-mu-induced apoptosis in WEHI-231 B-lymphoma-cells. Eur J Immunol 1995;25:1352-7.
22. Tewari M. Dixit VM. Recent advances in tumor-necrosis-factor and CD40 signaling. Curr Opin Genet Dev 1996;6:39-44.
23. Tamatani M, Che YH, Matsuzaki H, Ogawa S, Okado H, Miyake SI, et al. Tumor necrosis factor induces Bcl-2 and Bcl-X expression through NF-κB activation in primary hippocampal neurons. J Biol Chem 1999;274:8531-8.
24. Desagher S, Osen-Sand A, Nichols A, Eskes R, Montessuit S, Lauper S, et al. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J Cell Biol 1999;144:891-901.