메뉴 건너뛰기




Volumn 53, Issue 11, 2013, Pages 1202-1225

Grape Phytochemicals and Associated Health Benefits

Author keywords

antioxidant activity; cancer; cardiovascular disease; Grapes; phenolics; phytochemicals

Indexed keywords

ANTI-OXIDANT ACTIVITIES; CANCER; CARDIO-VASCULAR DISEASE; GRAPES; PHENOLICS; PHYTOCHEMICALS;

EID: 84884236081     PISSN: 10408398     EISSN: 15497852     Source Type: Journal    
DOI: 10.1080/10408398.2012.692408     Document Type: Article
Times cited : (151)

References (154)
  • 1
    • 33749321810 scopus 로고    scopus 로고
    • Phenolics and ripening in grape berries
    • Adams, D. O. 2006. Phenolics and ripening in grape berries. Am. J. Enol. Vitic., 57: 249 - 256.
    • (2006) Am. J. Enol. Vitic. , vol.57 , pp. 249-256
    • Adams, D.O.1
  • 2
    • 0037251437 scopus 로고    scopus 로고
    • Suppression of ultraviolet B exposure-mediated activation of NF-kappa B in normal human keratinocytes by resveratrol
    • Adhami, V. M., Afaq, F. and Ahmad, N. 2003. Suppression of ultraviolet B exposure-mediated activation of NF-kappa B in normal human keratinocytes by resveratrol. Neoplasia., 5: 74 - 82.
    • (2003) Neoplasia. , vol.5 , pp. 74-82
    • Adhami, V.M.1    Afaq, F.2    Ahmad, N.3
  • 3
    • 0037157034 scopus 로고    scopus 로고
    • Determination of antioxidant power of red and white wines by a new electrochemical method and its correlation with polyphenolic content
    • Alonso, Á. M., Domínguez, C., Guillén, D. A. and Barroso, C. G. 2002. Determination of antioxidant power of red and white wines by a new electrochemical method and its correlation with polyphenolic content. J. Agric. Food. Chem., 50: 3112 - 3115.
    • (2002) J. Agric. Food. Chem. , vol.50 , pp. 3112-3115
    • Alonso, A.1    Domínguez, C.2    Guillén, D.A.3    Barroso, C.G.4
  • 4
    • 0003964363 scopus 로고    scopus 로고
    • Cancer facts & figures
    • American Cancer Society, Available from
    • American Cancer Society. 2012. " Cancer facts & figures ". Available from http://www.cancer.org
    • (2012)
  • 6
    • 0345215163 scopus 로고    scopus 로고
    • Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice
    • Bagchi, D., Garg, A., Krohn, R. L., Bagchi, M., Bagchi, D. J., Balmoori, J. and Stohs, S. J. 1998. Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice. Gen. Pharmacol., 30: 771 - 776.
    • (1998) Gen. Pharmacol. , vol.30 , pp. 771-776
    • Bagchi, D.1    Garg, A.2    Krohn, R.L.3    Bagchi, M.4    Bagchi, D.J.5    Balmoori, J.6    Stohs, S.J.7
  • 7
    • 80053116397 scopus 로고    scopus 로고
    • Varietal differences among the phenolic profiles and antioxidant activities of seven table grape cultivars grown in the South of Italy based on chemometrics
    • Baiano, A. and Terracone, C. 2011. Varietal differences among the phenolic profiles and antioxidant activities of seven table grape cultivars grown in the South of Italy based on chemometrics. J. Agric. Food Chem., 59: 9815 - 9826.
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 9815-9826
    • Baiano, A.1    Terracone, C.2
  • 8
    • 0036733776 scopus 로고    scopus 로고
    • Suppression of 7,12-dimethylbenz(a) anthracene-induced mammary carcinogenesis in rats by resveratrol: Role of nuclear factor-κB, cyclooxygenase 2, and matrix metalloprotease 9
    • Banerjee, S., Bueso-Ramos, C. and Aggarwal, B. B. 2002. Suppression of 7,12-dimethylbenz(a) anthracene-induced mammary carcinogenesis in rats by resveratrol: Role of nuclear factor-κB, cyclooxygenase 2, and matrix metalloprotease 9. Cancer Res., 62: 4945 - 4954.
    • (2002) Cancer Res. , vol.62 , pp. 4945-4954
    • Banerjee, S.1    Bueso-Ramos, C.2    Aggarwal, B.B.3
  • 9
    • 0034695431 scopus 로고    scopus 로고
    • Estrogenic/antiestrogenic and scavenging properties of (E)- and (Z)-resveratrol
    • Basly, J. P., Marre-Fournier, F., Le Bail, J. C., Habrioux, G. and Chulia, A. J. 2000. Estrogenic/antiestrogenic and scavenging properties of (E)- and (Z)-resveratrol. Life Sci., 66: 769 - 777.
    • (2000) Life Sci. , vol.66 , pp. 769-777
    • Basly, J.P.1    Marre-Fournier, F.2    Le Bail, J.C.3    Habrioux, G.4    Chulia, A.J.5
  • 10
    • 0037193081 scopus 로고    scopus 로고
    • Biogeneration of C13-norisoprenoid compounds: Experiment supportive for an apo-carotenoid pathway in grapevines
    • Baumes, R., Wirth, J., Bureau, S., Gunata, Y. and Razungles, A. 2002. Biogeneration of C13-norisoprenoid compounds: Experiment supportive for an apo-carotenoid pathway in grapevines. Anal. Chim. Acta., 458: 3 - 14.
    • (2002) Anal. Chim. Acta. , vol.458 , pp. 3-14
    • Baumes, R.1    Wirth, J.2    Bureau, S.3    Gunata, Y.4    Razungles, A.5
  • 11
    • 74949098826 scopus 로고    scopus 로고
    • Grapes, wines, resveratrol, and heart health
    • Bertelli, A. A. and Das, D. K. 2009. Grapes, wines, resveratrol, and heart health. J. Cardiovasc. Pharmacol., 54: 468 - 476.
    • (2009) J. Cardiovasc. Pharmacol. , vol.54 , pp. 468-476
    • Bertelli, A.A.1    Das, D.K.2
  • 12
    • 0035886874 scopus 로고    scopus 로고
    • Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models
    • Bhat, K. P. L., Lantvit, D., Christov, K., Mehta, R. G., Moon, R. C. and Pezzuto, J. M. 2001. Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models. Cancer Res., 61: 7456 - 7463.
    • (2001) Cancer Res. , vol.61 , pp. 7456-7463
    • Bhat, K.P.L.1    Lantvit, D.2    Christov, K.3    Mehta, R.G.4    Moon, R.C.5    Pezzuto, J.M.6
  • 13
    • 0035881270 scopus 로고    scopus 로고
    • Resveratrol exhibits cytostatic and antiestrogenic properties with human endometrial adenocarcinoma (Ishikawa) cells
    • Bhat, K. P. L. and Pezzuto, J. M. 2001. Resveratrol exhibits cytostatic and antiestrogenic properties with human endometrial adenocarcinoma (Ishikawa) cells. Cancer Res., 61: 6137 - 6144.
    • (2001) Cancer Res. , vol.61 , pp. 6137-6144
    • Bhat, K.P.L.1    Pezzuto, J.M.2
  • 15
    • 80053286381 scopus 로고    scopus 로고
    • Opposing actions of rosiglitazone and resveratrol on mineralization in human vascular smooth muscle cells
    • Bruedigam, C., Eijken, M., Koedam, M., Chiba, H. and van Leeuwen, J. P. 2011. Opposing actions of rosiglitazone and resveratrol on mineralization in human vascular smooth muscle cells. J. Mol. Cell. Cardiol., 51: 862 - 871.
    • (2011) J. Mol. Cell. Cardiol. , vol.51 , pp. 862-871
    • Bruedigam, C.1    Eijken, M.2    Koedam, M.3    Chiba, H.4    van Leeuwen, J.P.5
  • 18
    • 82955165813 scopus 로고    scopus 로고
    • The protective role of natural phytoalexin resveratrol on inflammation, fibrosis and regeneration in cholestatic liver injury
    • Chan, C. C., Cheng, L.-Y., Lin, C.-L., Huang, Y.-H., Lin, H. C. and Lee, F. Y. 2011. The protective role of natural phytoalexin resveratrol on inflammation, fibrosis and regeneration in cholestatic liver injury. Mol. Nutr. Food Res., 55: 1841 - 1849.
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 1841-1849
    • Chan, C.C.1    Cheng, L.-Y.2    Lin, C.-L.3    Huang, Y.-H.4    Lin, H.C.5    Lee, F.Y.6
  • 19
    • 20344396620 scopus 로고    scopus 로고
    • Resveratrol inhibits angiotensin II-induced endothelin-1 gene expression and subsequent proliferation in rat aortic smooth muscle cells
    • Chao, H.-H., Juan, S.-H., Liu, J.-C., Yang, H.-Y., Yang, E., Cheng, T. H. and Shyu, K. G. 2005. Resveratrol inhibits angiotensin II-induced endothelin-1 gene expression and subsequent proliferation in rat aortic smooth muscle cells. Eur. J. Pharmcol., 515: 1 - 9.
    • (2005) Eur. J. Pharmcol. , vol.515 , pp. 1-9
    • Chao, H.-H.1    Juan, S.-H.2    Liu, J.-C.3    Yang, H.-Y.4    Yang, E.5    Cheng, T.H.6    Shyu, K.G.7
  • 21
    • 0029981730 scopus 로고    scopus 로고
    • Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta
    • Chen, C. and Pace-Asciak, C. R. 1996. Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta. Gen. Pharmacol., 27: 363 - 366.
    • (1996) Gen. Pharmacol. , vol.27 , pp. 363-366
    • Chen, C.1    Pace-Asciak, C.R.2
  • 22
    • 0027158765 scopus 로고
    • Antiplatelet effects and vasorelaxing action of some constituents of Formosan plants
    • Chung, M. I., Gan, K. H., Lin, C. N., Ko, F. N. and Teng, C. M. 1993. Antiplatelet effects and vasorelaxing action of some constituents of Formosan plants. J. Nat. Prod., 56: 929 - 934.
    • (1993) J. Nat. Prod. , vol.56 , pp. 929-934
    • Chung, M.I.1    Gan, K.H.2    Lin, C.N.3    Ko, F.N.4    Teng, C.M.5
  • 27
    • 0032860948 scopus 로고    scopus 로고
    • trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets
    • Dobrydneva, Y., Williams, R. L. and Blackmore, P. F. 1999. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br. J. Pharmacol., 128: 149 - 157.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 149-157
    • Dobrydneva, Y.1    Williams, R.L.2    Blackmore, P.F.3
  • 28
    • 69549138125 scopus 로고    scopus 로고
    • Grapes and cardiovascular disease
    • Dohadwala, M. M. and Vita, J. A. 2009. Grapes and cardiovascular disease. J Nutr., 139: 1788S - 1793S.
    • (2009) J Nutr. , vol.139
    • Dohadwala, M.M.1    Vita, J.A.2
  • 29
    • 0032911668 scopus 로고    scopus 로고
    • Resveratrol inhibits MAPK activity and nuclear translocation in coronary artery smooth muscle: Reversal of endothelin-1 stimulatory effects
    • El-Mowafy, A. M. and White, R. E. 1999. Resveratrol inhibits MAPK activity and nuclear translocation in coronary artery smooth muscle: Reversal of endothelin-1 stimulatory effects. FEBS Lett., 451: 63 - 67.
    • (1999) FEBS Lett. , vol.451 , pp. 63-67
    • El-Mowafy, A.M.1    White, R.E.2
  • 30
    • 0027396786 scopus 로고
    • Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine
    • Frankel, E. N., German, J. B., Kinsella, J. E., Parks, E. and Kinsella, J. E. 1993a. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. Lancet., 341: 454 - 457.
    • (1993) Lancet. , vol.341 , pp. 454-457
    • Frankel, E.N.1    German, J.B.2    Kinsella, J.E.3    Parks, E.4    Kinsella, J.E.5
  • 31
    • 0027447124 scopus 로고
    • Inhibition of human LDL oxidation by resveratrol
    • Frankel, E. N., Waterhouse, A. L. and Kinsella, J. E. 1993b. Inhibition of human LDL oxidation by resveratrol. Lancet., 341: 1103 - 1104.
    • (1993) Lancet. , vol.341 , pp. 1103-1104
    • Frankel, E.N.1    Waterhouse, A.L.2    Kinsella, J.E.3
  • 32
    • 0035849516 scopus 로고    scopus 로고
    • Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release
    • Freedman, J. E., Parker, C., Li, L., Perlman, J. A., Frei, B., Ivanov, V., Deak, L. R., Iafrati, M. D. and Folts, J. D. 2001. Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release. Circulation., 103: 2792 - 2798.
    • (2001) Circulation. , vol.103 , pp. 2792-2798
    • Freedman, J.E.1    Parker, C.2    Li, L.3    Perlman, J.A.4    Frei, B.5    Ivanov, V.6    Deak, L.R.7    Iafrati, M.D.8    Folts, J.D.9
  • 33
    • 0035989506 scopus 로고    scopus 로고
    • Potential health benefits from the flavonoids in grape products on vascular disease
    • Folts, J. D. 2002. Potential health benefits from the flavonoids in grape products on vascular disease. Adv. Exp. Med. Biol., 505: 95 - 111.
    • (2002) Adv. Exp. Med. Biol. , vol.505 , pp. 95-111
    • Folts, J.D.1
  • 34
    • 0033591299 scopus 로고    scopus 로고
    • Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids
    • Frémont, L., Belguendouz, L. and Delpal, S. 1999. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids. Life Sci., 64: 2511 - 2521.
    • (1999) Life Sci. , vol.64 , pp. 2511-2521
    • Frémont, L.1    Belguendouz, L.2    Delpal, S.3
  • 35
    • 0031444281 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor
    • Gehm, B. D., McAndrews, J. M., Chien, P. Y. and Jameson, J. L. 1997. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. Proc. Natl. Acad. Sci. USA, 94: 14138 - 14143.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14138-14143
    • Gehm, B.D.1    McAndrews, J.M.2    Chien, P.Y.3    Jameson, J.L.4
  • 36
    • 84858326289 scopus 로고    scopus 로고
    • Recent applications of grape polyphenols in foods, beverages and supplements
    • Gollücke, A. P. 2010. Recent applications of grape polyphenols in foods, beverages and supplements. Recent Pat Food Nutr. Agric., 2: 105 - 109.
    • (2010) Recent Pat Food Nutr. Agric. , vol.2 , pp. 105-109
    • Gollücke, A.P.1
  • 37
    • 34447264803 scopus 로고    scopus 로고
    • HPLC analysis of diverse grape and wine phenolics using direct injection and multidetection by DAD and fluorescence
    • Gómez-Alonso, S., García-Romero, E. and Hermosín-Gutiérrez, I. 2007. HPLC analysis of diverse grape and wine phenolics using direct injection and multidetection by DAD and fluorescence. J. Food Composi. Anal., 20: 618 - 626.
    • (2007) J. Food Composi. Anal. , vol.20 , pp. 618-626
    • Gómez-Alonso, S.1    García-Romero, E.2    Hermosín-Gutiérrez, I.3
  • 38
    • 0141850470 scopus 로고    scopus 로고
    • Screening of foods containing proanthocyanidins and their structural characterization using LC-MS/MS and thiolytic degradation
    • Gu, L., Kelm, M. A., Hammerstone, J. F., Beecher, G., Holden, J., Haytowitz, D. and Prior, R. L. 2003. Screening of foods containing proanthocyanidins and their structural characterization using LC-MS/MS and thiolytic degradation. J. Agric. Food Chem., 51: 7513 - 7521.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 7513-7521
    • Gu, L.1    Kelm, M.A.2    Hammerstone, J.F.3    Beecher, G.4    Holden, J.5    Haytowitz, D.6    Prior, R.L.7
  • 40
    • 0035965945 scopus 로고    scopus 로고
    • Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention
    • Hayes, J. D. and McMahon, M. 2001. Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention. Cancer Lett., 174: 103 - 113.
    • (2001) Cancer Lett. , vol.174 , pp. 103-113
    • Hayes, J.D.1    McMahon, M.2
  • 41
    • 0034658374 scopus 로고    scopus 로고
    • Flavonols, flavones and flavanols - nature, occurrence and dietary burden
    • Hollman, P. C. H. and Arts, I. C. W. 2000. Flavonols, flavones and flavanols - nature, occurrence and dietary burden. J. Sci. Food Agric., 80: 1081 - 1093.
    • (2000) J. Sci. Food Agric. , vol.80 , pp. 1081-1093
    • Hollman, P.C.H.1    Arts, I.C.W.2
  • 42
    • 0141612106 scopus 로고    scopus 로고
    • Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: Structure-activity relationship and mechanisms involved
    • Hou, D. X., Ose, T., Lin, S., Harazoro, K., Imamura, I., Kubo, M., Uto, T., Terahara, N., Yoshimoto, M. and Fujii, M. 2003. Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: Structure-activity relationship and mechanisms involved. Int. J. Oncol., 23: 705 - 712.
    • (2003) Int. J. Oncol. , vol.23 , pp. 705-712
    • Hou, D.X.1    Ose, T.2    Lin, S.3    Harazoro, K.4    Imamura, I.5    Kubo, M.6    Uto, T.7    Terahara, N.8    Yoshimoto, M.9    Fujii, M.10
  • 43
    • 0033173041 scopus 로고    scopus 로고
    • Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials
    • Hsieh, T. C., Burfeind, P., Laud, K., Bacher, J. M., Traganos, F., Darzynkiewicz, Z. and Wu, J. M. 1999a. Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials. Int. J. Oncol., 15: 245 - 252.
    • (1999) Int. J. Oncol. , vol.15 , pp. 245-252
    • Hsieh, T.C.1    Burfeind, P.2    Laud, K.3    Bacher, J.M.4    Traganos, F.5    Darzynkiewicz, Z.6    Wu, J.M.7
  • 44
    • 0033152949 scopus 로고    scopus 로고
    • Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1) and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G(2)
    • Hsieh, T. C., Juan, G., Darzynkiewicz, Z. and Wu, J. M. 1999b. Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1) and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G(2). Cancer Res., 59: 2596 - 2601.
    • (1999) Cancer Res. , vol.59 , pp. 2596-2601
    • Hsieh, T.C.1    Juan, G.2    Darzynkiewicz, Z.3    Wu, J.M.4
  • 45
    • 0034073147 scopus 로고    scopus 로고
    • Grape-derived chemopreventive agent resveratrol decreases prostate-specific antigen (PSA) expression in LNCaP cells by an androgen receptor (AR)-independent mechanism
    • Hsieh, T. C. and Wu, J. M. 2000. Grape-derived chemopreventive agent resveratrol decreases prostate-specific antigen (PSA) expression in LNCaP cells by an androgen receptor (AR)-independent mechanism. Anticancer Res., 20: 225 - 228.
    • (2000) Anticancer Res. , vol.20 , pp. 225-228
    • Hsieh, T.C.1    Wu, J.M.2
  • 46
    • 0032939164 scopus 로고    scopus 로고
    • Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway
    • Huang, C., Ma, W. Y., Goranson, A. and Dong, Z. 1999. Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway. Carcinogenesis., 20: 237 - 242.
    • (1999) Carcinogenesis. , vol.20 , pp. 237-242
    • Huang, C.1    Ma, W.Y.2    Goranson, A.3    Dong, Z.4
  • 47
    • 33745968572 scopus 로고    scopus 로고
    • Grape phytochemicals: A bouquet of old and new nutraceuticals for human health
    • Iriti, M. and Faoro, F. 2006. Grape phytochemicals: A bouquet of old and new nutraceuticals for human health. Med. Hypoth., 67: 833 - 838.
    • (2006) Med. Hypoth. , vol.67 , pp. 833-838
    • Iriti, M.1    Faoro, F.2
  • 48
    • 69549115609 scopus 로고    scopus 로고
    • Bioactivity of grape chemicals for human health
    • Iriti, M. and Faoro, F. 2009. Bioactivity of grape chemicals for human health. Nat Prod Commun, 4: 611 - 634.
    • (2009) Nat Prod Commun , vol.4 , pp. 611-634
    • Iriti, M.1    Faoro, F.2
  • 49
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J. D. and Yamamoto, M. 1999. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes. Dev., 13: 76 - 86.
    • (1999) Genes. Dev. , vol.13 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6    Yamamoto, M.7
  • 50
    • 80054691700 scopus 로고    scopus 로고
    • Identification of polyphenolic compounds in red and white grape varieties grown in R. Macedonia and changes of their content during ripening
    • Ivanova, V., Stefova, M., Vojnoski, B., Dörnyei, A., Márk, L., Dimovska, V., Stafilov, T. and Kilár, F. 2011. Identification of polyphenolic compounds in red and white grape varieties grown in R. Macedonia and changes of their content during ripening. Food Res. Int., 44: 2851 - 2860.
    • (2011) Food Res. Int. , vol.44 , pp. 2851-2860
    • Ivanova, V.1    Stefova, M.2    Vojnoski, B.3    Dörnyei, A.4    Márk, L.5    Dimovska, V.6    Stafilov, T.7    Kilár, F.8
  • 51
    • 0035922171 scopus 로고    scopus 로고
    • Protective effects of resveratrol on hydrogen peroxide-induced apoptosis in rat pheochromocytoma (PC12) cells
    • Jang, J. H. and Surh, YJ. 2001. Protective effects of resveratrol on hydrogen peroxide-induced apoptosis in rat pheochromocytoma (PC12) cells. Mutat. Res., 496: 181 - 190.
    • (2001) Mutat. Res. , vol.496 , pp. 181-190
    • Jang, J.H.1    Surh, Y.J.2
  • 54
    • 0036301453 scopus 로고    scopus 로고
    • Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines
    • Joe, A. K., Liu, H., Suzui, M., Vural, M. E., Xiao, D. and Weinstein, I. B. 2002. Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines. Clin. Canc. Res., 8: 893 - 903.
    • (2002) Clin. Canc. Res. , vol.8 , pp. 893-903
    • Joe, A.K.1    Liu, H.2    Suzui, M.3    Vural, M.E.4    Xiao, D.5    Weinstein, I.B.6
  • 57
    • 53449095485 scopus 로고    scopus 로고
    • Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system
    • Katiyar, S. K. 2008. Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system. Mol. Nutr. Food Res., 52: S71 - S76.
    • (2008) Mol. Nutr. Food Res. , vol.52
    • Katiyar, S.K.1
  • 58
    • 69549109965 scopus 로고    scopus 로고
    • Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products
    • Kaur, M., Agarwal, C. and Agarwal, R. 2009. Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products. J. Nutr., 139: 1806S - 1812S.
    • (2009) J. Nutr. , vol.139
    • Kaur, M.1    Agarwal, C.2    Agarwal, R.3
  • 60
    • 1642576020 scopus 로고    scopus 로고
    • Antiproliferative effect of resveratrol in human prostate carcinoma cells
    • Kim, Y. A., Rhee, S. H., Park, K. Y. and Choi, Y. H. 2003. Antiproliferative effect of resveratrol in human prostate carcinoma cells. J. Med. Food, 6: 273 - 280.
    • (2003) J. Med. Food , vol.6 , pp. 273-280
    • Kim, Y.A.1    Rhee, S.H.2    Park, K.Y.3    Choi, Y.H.4
  • 61
    • 0034991938 scopus 로고    scopus 로고
    • Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice
    • Kimura, Y. and Okuda, H. 2001. Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice. J. Nutr., 131: 1844 - 1849.
    • (2001) J. Nutr. , vol.131 , pp. 1844-1849
    • Kimura, Y.1    Okuda, H.2
  • 62
    • 13444269361 scopus 로고    scopus 로고
    • Resveratrol reduces oxidation and proliferation of human retinal pigment epithelial cells via extracellular signal-regulated kinase inhibition
    • King, R. E., Kent, K. D. and Bomser, J. A. 2005. Resveratrol reduces oxidation and proliferation of human retinal pigment epithelial cells via extracellular signal-regulated kinase inhibition. Chem. Biol. Interact., 151: 143 - 149.
    • (2005) Chem. Biol. Interact. , vol.151 , pp. 143-149
    • King, R.E.1    Kent, K.D.2    Bomser, J.A.3
  • 63
    • 0002621769 scopus 로고
    • Possible mechanisms for the protective role of antioxidants in wine and plant foods
    • Kinsella, J. E., Frankel, E., German, B. and Kanner, J. 1993. Possible mechanisms for the protective role of antioxidants in wine and plant foods. Food Technol., 47: 85 - 89.
    • (1993) Food Technol. , vol.47 , pp. 85-89
    • Kinsella, J.E.1    Frankel, E.2    German, B.3    Kanner, J.4
  • 64
    • 16444382588 scopus 로고    scopus 로고
    • Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets
    • Kundu, J. K., Chun, K.-S., Kim, S. O. and Surh, Y.-J. 2004. Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets. Biofactors., 21: 33 - 39.
    • (2004) Biofactors. , vol.21 , pp. 33-39
    • Kundu, J.K.1    Chun, K.-S.2    Kim, S.O.3    Surh, Y.-J.4
  • 65
    • 0041303655 scopus 로고    scopus 로고
    • Phenylpropanoids from medicinal plants: Distribution, classification, structural analysis and biological activity
    • Kurkin, V. A. 2003. Phenylpropanoids from medicinal plants: Distribution, classification, structural analysis and biological activity. Chem. Nat. Compd., 39: 123 - 153.
    • (2003) Chem. Nat. Compd. , vol.39 , pp. 123-153
    • Kurkin, V.A.1
  • 66
    • 2342653588 scopus 로고    scopus 로고
    • Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts
    • Kutuk, O., Adli, M., Poli, G. and Basaga, H. 2004. Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts. BioFactors., 20: 1 - 10.
    • (2004) BioFactors. , vol.20 , pp. 1-10
    • Kutuk, O.1    Adli, M.2    Poli, G.3    Basaga, H.4
  • 68
    • 79960442457 scopus 로고    scopus 로고
    • Trans-resveratrol inhibits phosphorylation of Smad2/3 and represses FSHβ gene expression by a SirT1-independent pathway in LβT2 gonadotrope cells
    • Lan, D. B., Lu, M., Sharma, S., Mellon, P. L., Olefsky, J. M. and Webster, N. J. 2011. Trans-resveratrol inhibits phosphorylation of Smad2/3 and represses FSHβ gene expression by a SirT1-independent pathway in LβT2 gonadotrope cells. Reprod. Toxicol., 32: 85 - 92.
    • (2011) Reprod. Toxicol. , vol.32 , pp. 85-92
    • Lan, D.B.1    Lu, M.2    Sharma, S.3    Mellon, P.L.4    Olefsky, J.M.5    Webster, N.J.6
  • 69
    • 0031399387 scopus 로고    scopus 로고
    • Breeding muscadine and southern bunch grapes
    • Lane, R. 1997. Breeding muscadine and southern bunch grapes. Fruit Var. J., 51: 144 - 148.
    • (1997) Fruit Var. J. , vol.51 , pp. 144-148
    • Lane, R.1
  • 70
    • 46849095716 scopus 로고
    • The production of resveratrol by Vitis vinifera and other members of the Vitaceae as a response to infection or injury
    • Langcake, P. and Pryce, R. J. 1976. The production of resveratrol by Vitis vinifera and other members of the Vitaceae as a response to infection or injury. Physiol. Plant Pathol., 9: 77 - 86.
    • (1976) Physiol. Plant Pathol. , vol.9 , pp. 77-86
    • Langcake, P.1    Pryce, R.J.2
  • 71
    • 5744234431 scopus 로고    scopus 로고
    • The grape and wine polyphenol piceatannol is a potent inducer of apoptosis in human SK-Mel-28 melanoma cells
    • Larrosa, M., Tomás-Barberán, F. A. and Espín, J. C. 2004. The grape and wine polyphenol piceatannol is a potent inducer of apoptosis in human SK-Mel-28 melanoma cells. Eur. J. Nutr., 43: 275 - 284.
    • (2004) Eur. J. Nutr. , vol.43 , pp. 275-284
    • Larrosa, M.1    Tomás-Barberán, F.A.2    Espín, J.C.3
  • 72
    • 0037419741 scopus 로고    scopus 로고
    • Anthocyanins protect against DNA damage induced by tert-butyl-hydroperoxide in rat smooth muscle and hepatoma cells
    • Lazzé, M. C., Pizzala, R., Savio, M., Stivala, L. A., Prosperi, E. and Bianchi, L. 2003. Anthocyanins protect against DNA damage induced by tert-butyl-hydroperoxide in rat smooth muscle and hepatoma cells. Mutat. Res., 535: 103 - 115.
    • (2003) Mutat. Res. , vol.535 , pp. 103-115
    • Lazzé, M.C.1    Pizzala, R.2    Savio, M.3    Stivala, L.A.4    Prosperi, E.5    Bianchi, L.6
  • 73
    • 79956097572 scopus 로고    scopus 로고
    • Extracellular HIV-1 Tat upregulates TNF-α dependent MCP-1/CCL2 production via activation of ERK1/2 pathway in rat hippocampal slice cultures: Inhibition by resveratrol, a polyphenolic phytostilbene
    • Lee, E. O., Kim, S. E., Park, H. K., Kang, J. L. and Chong, Y. H. 2011. Extracellular HIV-1 Tat upregulates TNF-α dependent MCP-1/CCL2 production via activation of ERK1/2 pathway in rat hippocampal slice cultures: Inhibition by resveratrol, a polyphenolic phytostilbene. Exp. Neurol., 229: 399 - 408.
    • (2011) Exp. Neurol. , vol.229 , pp. 399-408
    • Lee, E.O.1    Kim, S.E.2    Park, H.K.3    Kang, J.L.4    Chong, Y.H.5
  • 74
    • 0032913414 scopus 로고    scopus 로고
    • Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
    • Lu, R. and Serrero, G. 1999. Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells. J. Cell. Physiol., 179: 297 - 304.
    • (1999) J. Cell. Physiol. , vol.179 , pp. 297-304
    • Lu, R.1    Serrero, G.2
  • 76
    • 80053050460 scopus 로고    scopus 로고
    • Phenolics and antioxidant capacity of table grape (Vitis vinifera L.) cultivars grown in Chile
    • Lutz, M., Jorquera, K., Cancino, B., Ruby, R. and Henriquez, C. 2011. Phenolics and antioxidant capacity of table grape (Vitis vinifera L.) cultivars grown in Chile. J. Food Sci., 76: C1088 - C1093.
    • (2011) J. Food Sci. , vol.76
    • Lutz, M.1    Jorquera, K.2    Cancino, B.3    Ruby, R.4    Henriquez, C.5
  • 77
    • 33646521729 scopus 로고    scopus 로고
    • Flavonols in grapes, grape products and wines: Burden, profile and influential parameters
    • Makris, D. P., Kallithraka, S. and Kefalas, P. 2006. Flavonols in grapes, grape products and wines: Burden, profile and influential parameters. J. Food Composi. Anal., 19: 396 - 404.
    • (2006) J. Food Composi. Anal. , vol.19 , pp. 396-404
    • Makris, D.P.1    Kallithraka, S.2    Kefalas, P.3
  • 78
    • 0034660659 scopus 로고    scopus 로고
    • Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-κB, activator protein-1, and apoptosis: Potential role of reactive oxygen intermediates and lipid peroxidation
    • Manna, S. K., Mukhopadhyay, A. and Aggarwal, B. B. 2000. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-κB, activator protein-1, and apoptosis: Potential role of reactive oxygen intermediates and lipid peroxidation. J. Immunol., 164: 6509 - 6519.
    • (2000) J. Immunol. , vol.164 , pp. 6509-6519
    • Manna, S.K.1    Mukhopadhyay, A.2    Aggarwal, B.B.3
  • 79
    • 1542285473 scopus 로고    scopus 로고
    • Resveratrol, a polyphenol found in grapes, suppresses oxidative damage and stimulates apoptosis during early colonic inflammation in rats
    • Martín, A. R., Villegas, I., La Casa, C. and de la Lastra, C. A. 2004. Resveratrol, a polyphenol found in grapes, suppresses oxidative damage and stimulates apoptosis during early colonic inflammation in rats. Biochem. Pharmacol., 67: 1399 - 1410.
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 1399-1410
    • Martín, A.R.1    Villegas, I.2    La Casa, C.3    de la Lastra, C.A.4
  • 80
    • 35448949009 scopus 로고    scopus 로고
    • Flavonoid and aromatic characterisation of cv. Albarín blanco (Vitis vinifera L.)
    • Masa, A. and Vilanova, M. 2008. Flavonoid and aromatic characterisation of cv. Albarín blanco (Vitis vinifera L.). Food Chem., 107: 273 - 281.
    • (2008) Food Chem. , vol.107 , pp. 273-281
    • Masa, A.1    Vilanova, M.2
  • 82
    • 0035114407 scopus 로고    scopus 로고
    • The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor
    • Meiers, S., Kemeny, M., Weyand, U., Gastpar, R., von Angerer, E. and Marko, D. 2001. The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor. J. Agric. Food Chem., 49: 958 - 962.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 958-962
    • Meiers, S.1    Kemeny, M.2    Weyand, U.3    Gastpar, R.4    von Angerer, E.5    Marko, D.6
  • 83
    • 0001479611 scopus 로고    scopus 로고
    • Inhibition of human low-density lipoprotein oxidation in relation to composition of phenolic antioxidants in grapes (Vitis vinifera)
    • Meyer, A. S., Yi, O. S., Pearson, D. A., Waterhouse, A. L. and Frankel, E. N. 1997. Inhibition of human low-density lipoprotein oxidation in relation to composition of phenolic antioxidants in grapes (Vitis vinifera). J. Agric. Food Chem., 5: 1638 - 1643.
    • (1997) J. Agric. Food Chem. , vol.5 , pp. 1638-1643
    • Meyer, A.S.1    Yi, O.S.2    Pearson, D.A.3    Waterhouse, A.L.4    Frankel, E.N.5
  • 84
    • 83455170637 scopus 로고    scopus 로고
    • The Impact of Wine, Grapes and Grape Products on the American Economy 2007: Family Businesses Building Value
    • MKF Research, St. Helena, California: The Wine Business Center
    • MKF Research. 2007. The Impact of Wine, Grapes and Grape Products on the American Economy 2007: Family Businesses Building Value.: 1 - 22. St. Helena, California: The Wine Business Center.
    • (2007) , pp. 1-22
  • 85
    • 78649436142 scopus 로고    scopus 로고
    • Dose-dependency of resveratrol in providing health benefits
    • Mukherjee, S., Dudley, J. I. and Das, D. K. 2010. Dose-dependency of resveratrol in providing health benefits. Dose-Response., 8: 478 - 500.
    • (2010) Dose-Response. , vol.8 , pp. 478-500
    • Mukherjee, S.1    Dudley, J.I.2    Das, D.K.3
  • 86
    • 0036498948 scopus 로고    scopus 로고
    • Interactive gene expression pattern in prostate cancer cells exposed to phenolic antioxidants
    • Narayanan, B. A., Narayanan, N. K., Stoner, G. D. and Bullock, B. P. 2002. Interactive gene expression pattern in prostate cancer cells exposed to phenolic antioxidants. Life Sci., 70: 1821 - 1839.
    • (2002) Life Sci. , vol.70 , pp. 1821-1839
    • Narayanan, B.A.1    Narayanan, N.K.2    Stoner, G.D.3    Bullock, B.P.4
  • 87
    • 69449092522 scopus 로고    scopus 로고
    • Review of the pharmacological effects of Vitis vinifera (grape) and its bioactive compounds
    • Nassiri-Asl, M. and Hosseinzadeh, H. 2009. Review of the pharmacological effects of Vitis vinifera (grape) and its bioactive compounds. Phytother Res., 23: 1197 - 1204.
    • (2009) Phytother Res. , vol.23 , pp. 1197-1204
    • Nassiri-Asl, M.1    Hosseinzadeh, H.2
  • 88
    • 0036894497 scopus 로고    scopus 로고
    • Comparison of the antioxidant effects of Concord grape juice flavonoids alpha-tocopherol on markers of oxidative stress in healthy adults
    • O'Byrne, D. J., Devaraj, S., Grundy, S. M. and Jialal, I. 2002. Comparison of the antioxidant effects of Concord grape juice flavonoids alpha-tocopherol on markers of oxidative stress in healthy adults. Am. J. Clin. Nutr., 76: 1367 - 1374.
    • (2002) Am. J. Clin. Nutr. , vol.76 , pp. 1367-1374
    • O'Byrne, D.J.1    Devaraj, S.2    Grundy, S.M.3    Jialal, I.4
  • 89
    • 0037089067 scopus 로고    scopus 로고
    • Resveratrol and vitamin C as antioxidants in blood platelets
    • Olas, B. and Wachowicz, B. 2002. Resveratrol and vitamin C as antioxidants in blood platelets. Thromb. Res., 106: 143 - 148.
    • (2002) Thromb. Res. , vol.106 , pp. 143-148
    • Olas, B.1    Wachowicz, B.2
  • 91
    • 0032410759 scopus 로고    scopus 로고
    • Grape juice but not orange or grapefruit juice inhibits platelet activity in dogs and monkeys
    • Osman, H. E., Maalej, N., Shanmuganayagam, D. and Folts, J. D. 1998. Grape juice but not orange or grapefruit juice inhibits platelet activity in dogs and monkeys. J. Nutr., 128: 2307 - 2312.
    • (1998) J. Nutr. , vol.128 , pp. 2307-2312
    • Osman, H.E.1    Maalej, N.2    Shanmuganayagam, D.3    Folts, J.D.4
  • 92
    • 0032994036 scopus 로고    scopus 로고
    • Effect of resveratrol and some other natural compounds on tyrosine kinase activity and on cytolysis
    • Palmieri, L., Mameli, M. and Ronca, G. 1999. Effect of resveratrol and some other natural compounds on tyrosine kinase activity and on cytolysis. Drugs Exp. Clin. Res., 25: 79 - 85.
    • (1999) Drugs Exp. Clin. Res. , vol.25 , pp. 79-85
    • Palmieri, L.1    Mameli, M.2    Ronca, G.3
  • 93
    • 65249164833 scopus 로고    scopus 로고
    • Resveratrol: A promising agent in promoting cardioprotection against coronary heart disease
    • Penumathsa, S. V. and Maulika, N. 2009. Resveratrol: A promising agent in promoting cardioprotection against coronary heart disease. Can. J. Physiol. Pharmacol., 87: 275 - 286.
    • (2009) Can. J. Physiol. Pharmacol. , vol.87 , pp. 275-286
    • Penumathsa, S.V.1    Maulika, N.2
  • 94
    • 84862208884 scopus 로고    scopus 로고
    • Phenolic profile of Sercial and Tinta Negra Vitis vinifera L. grape skins by HPLC-DAD-ESI-MSn
    • doi
    • Perestrelo, R., Lu, Y., Santos, S., Silvestre, A. J. D., Neto, C. P., Câmara, J. S. and Rocha, S. M. 2012. Phenolic profile of Sercial and Tinta Negra Vitis vinifera L. grape skins by HPLC-DAD-ESI-MSn. Food Chem., 135: 94 - 104. doi: http://dx.doi.org/10.1016/j.foodchem.2012.04.102
    • (2012) Food Chem. , vol.135 , pp. 94-104
    • Perestrelo, R.1    Lu, Y.2    Santos, S.3    Silvestre, A.J.D.4    Neto, C.P.5    Câmara, J.S.6    Rocha, S.M.7
  • 95
    • 61549115347 scopus 로고    scopus 로고
    • Grape products and cardiovascular disease risk factors
    • Pérez-Jiménez, J. and Saura-Calixto, F. 2008. Grape products and cardiovascular disease risk factors. Nutr Res Rev., 21: 158 - 173.
    • (2008) Nutr Res Rev. , vol.21 , pp. 158-173
    • Pérez-Jiménez, J.1    Saura-Calixto, F.2
  • 97
    • 0028036133 scopus 로고
    • Oligomeric and polymeric procyanidins from grape seeds
    • Prieur, C., Rigaud, J., Cheynier, V. and Moutounet, M. 1994. Oligomeric and polymeric procyanidins from grape seeds. Phytochem, 36: 781 - 784.
    • (1994) Phytochem , vol.36 , pp. 781-784
    • Prieur, C.1    Rigaud, J.2    Cheynier, V.3    Moutounet, M.4
  • 100
    • 77955013223 scopus 로고    scopus 로고
    • Anti-atherogenic effects of resveratrol
    • Ramprasath, V. R. and Jones, P. J. 2010. Anti-atherogenic effects of resveratrol. Eur J Clin Nutr., 64: 660 - 668.
    • (2010) Eur J Clin Nutr. , vol.64 , pp. 660-668
    • Ramprasath, V.R.1    Jones, P.J.2
  • 101
    • 79960110969 scopus 로고    scopus 로고
    • Synergism between resveratrol and other phytochemicals: Implications for obesity and osteoporosis
    • Rayalam, S., Della-Fera, M. A. and Baile, C. A. 2011. Synergism between resveratrol and other phytochemicals: Implications for obesity and osteoporosis. Mol. Nutr. Food Res., 55: 1177 - 1185.
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 1177-1185
    • Rayalam, S.1    Della-Fera, M.A.2    Baile, C.A.3
  • 102
    • 0141820140 scopus 로고
    • Diversity of North American species of Vitis
    • Remaily, G. W. 1987. Diversity of North American species of Vitis. Plant Gen. Resour. Nwslt., 71: 25 - 30.
    • (1987) Plant Gen. Resour. Nwslt. , vol.71 , pp. 25-30
    • Remaily, G.W.1
  • 103
    • 0026651085 scopus 로고
    • Wine, alcohol, platelets, and the French paradox for coronary heart disease
    • Renaud, S. and de Lorgeril, M. 1992. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet., 339: 1523 - 1526.
    • (1992) Lancet. , vol.339 , pp. 1523-1526
    • Renaud, S.1    de Lorgeril, M.2
  • 104
    • 0002046322 scopus 로고
    • The anthocyanins of grapes and wines
    • In: Markakis P., editors New York, New York,: Academic Press
    • Riberau-Gayon, P. 1982. " The anthocyanins of grapes and wines. pp. 209-244 ". In Anthocyanins as Food Colors, Edited by: Markakis, P. New York: Academic Press.
    • (1982) Anthocyanins as Food Colors , pp. 209-244
    • Riberau-Gayon, P.1
  • 105
    • 20344387491 scopus 로고    scopus 로고
    • Effects of resveratrol, piceatannol, triacetoxystilbene, and genistein on the inflammatory response of human peripheral blood leukocytes
    • Richard, N., Porath, D., Radspieler, A. and Schwager, J. 2005. Effects of resveratrol, piceatannol, triacetoxystilbene, and genistein on the inflammatory response of human peripheral blood leukocytes. Mol. Nutr. Food Res., 49: 431 - 442.
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 431-442
    • Richard, N.1    Porath, D.2    Radspieler, A.3    Schwager, J.4
  • 106
    • 0037023981 scopus 로고    scopus 로고
    • Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol
    • Rimando, A. M., Cuendet, M., Desmarchelier, C., Mehta, R. G., Pezzuto, J. M. and Duke, S. O. 2002. Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol. J. Agric. Food Chem., 50: 3453 - 3457.
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 3453-3457
    • Rimando, A.M.1    Cuendet, M.2    Desmarchelier, C.3    Mehta, R.G.4    Pezzuto, J.M.5    Duke, S.O.6
  • 107
    • 56249132708 scopus 로고    scopus 로고
    • Biological/chemopreventive activity of stilbenes and their effect on colon cancer
    • Rimando, A. M. and Suh, N. 2008. Biological/chemopreventive activity of stilbenes and their effect on colon cancer. Planta Med., 74: 1635 - 1643.
    • (2008) Planta Med. , vol.74 , pp. 1635-1643
    • Rimando, A.M.1    Suh, N.2
  • 108
    • 79955571162 scopus 로고    scopus 로고
    • Phenolic compounds and antioxidant activity of seed and skin extracts of red grape (Vitis vinifera and Vitis labrusca) pomace from Brazilian winemaking
    • Rockenbach, I. I., Gonzaga, L. V., Rizelio, V. M., de Souza Schmidt Gonçalves, A. E., Genovese, M. I. and Fett, R. 2011. Phenolic compounds and antioxidant activity of seed and skin extracts of red grape (Vitis vinifera and Vitis labrusca) pomace from Brazilian winemaking. Food Res. Int., 44: 897 - 901.
    • (2011) Food Res. Int. , vol.44 , pp. 897-901
    • Rockenbach, I.I.1    Gonzaga, L.V.2    Rizelio, V.M.3    de Souza Schmidt Gonçalves, A.E.4    Genovese, M.I.5    Fett, R.6
  • 111
    • 77953711040 scopus 로고    scopus 로고
    • Resveratrol protects against experimental stroke: Putative neuroprotective role of heme oxygenase 1
    • Sakata, Y., Zhuang, H., Kwansa, H., Koehler, R. C. and Doré, S. 2010. Resveratrol protects against experimental stroke: Putative neuroprotective role of heme oxygenase 1. Exp. Neurol., 224: 325 - 329.
    • (2010) Exp. Neurol. , vol.224 , pp. 325-329
    • Sakata, Y.1    Zhuang, H.2    Kwansa, H.3    Koehler, R.C.4    Doré, S.5
  • 113
    • 0033395927 scopus 로고    scopus 로고
    • Anthocyanin-DNA copigmentation complex: Mutual protection against oxidative damage
    • Sarma, A. D. and Sharma, R. 1999. Anthocyanin-DNA copigmentation complex: Mutual protection against oxidative damage. Phytochemistry, 52: 1313 - 1318.
    • (1999) Phytochemistry , vol.52 , pp. 1313-1318
    • Sarma, A.D.1    Sharma, R.2
  • 115
    • 0035527493 scopus 로고    scopus 로고
    • Estrogenic activity of naturally occurring anthocyanidins
    • Schmitt, E. and Stopper, H. 2001. Estrogenic activity of naturally occurring anthocyanidins. Nutr. Cancer, 41: 145 - 149.
    • (2001) Nutr. Cancer , vol.41 , pp. 145-149
    • Schmitt, E.1    Stopper, H.2
  • 116
    • 0034730942 scopus 로고    scopus 로고
    • Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells
    • Schneider, Y., Vincent, F., Duranton, B., Badolo, L., Gossé, F., Bergmann, C., Seiler, N. and Raul, F. 2000. Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells. Cancer Lett., 158: 85 - 91.
    • (2000) Cancer Lett. , vol.158 , pp. 85-91
    • Schneider, Y.1    Vincent, F.2    Duranton, B.3    Badolo, L.4    Gossé, F.5    Bergmann, C.6    Seiler, N.7    Raul, F.8
  • 118
    • 0036900283 scopus 로고    scopus 로고
    • Grape seed and grape skin extracts elicit a greater antiplatelet effect when used in combination than when used individually in dogs and humans
    • Shanmuganayagam, D., Beahm, M. R., Osman, H. E., Krueger, C. G., Reed, J. D. and Folts, J. D. 2002. Grape seed and grape skin extracts elicit a greater antiplatelet effect when used in combination than when used individually in dogs and humans. J. Nutr., 132: 3592 - 3598.
    • (2002) J. Nutr. , vol.132 , pp. 3592-3598
    • Shanmuganayagam, D.1    Beahm, M.R.2    Osman, H.E.3    Krueger, C.G.4    Reed, J.D.5    Folts, J.D.6
  • 119
    • 1642559404 scopus 로고    scopus 로고
    • Polyphenolics in grape seeds-biochemistry and functionality
    • Shi, J., Yu, J., Pohorly, J. E. and Kakuda, Y. 2003. Polyphenolics in grape seeds-biochemistry and functionality. J. Med. Food, 6: 291 - 299.
    • (2003) J. Med. Food , vol.6 , pp. 291-299
    • Shi, J.1    Yu, J.2    Pohorly, J.E.3    Kakuda, Y.4
  • 120
    • 0036962164 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK- and p53-dependent mechanism
    • Shih, A., Davis, F. B., Lin, H. Y. and Davis, P. J. 2002. Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK- and p53-dependent mechanism. J. Clin. Endocrin. Metabol., 87: 1223 - 1232.
    • (2002) J. Clin. Endocrin. Metabol. , vol.87 , pp. 1223-1232
    • Shih, A.1    Davis, F.B.2    Lin, H.Y.3    Davis, P.J.4
  • 121
    • 0002256765 scopus 로고
    • Concentration of the phytoalexin resveratrol in wine
    • Siemann, E. H. and Creasy, L. L. 1992. Concentration of the phytoalexin resveratrol in wine. Am. J. Enol. Vitic., 43: 49 - 52.
    • (1992) Am. J. Enol. Vitic. , vol.43 , pp. 49-52
    • Siemann, E.H.1    Creasy, L.L.2
  • 122
    • 0014622923 scopus 로고
    • Phenolic substances in grapes and wine, and their significance
    • Singleton, V. L. and Esau, P. 1969. Phenolic substances in grapes and wine, and their significance. Adv. Food Res. Suppl., 1: 1 - 282.
    • (1969) Adv. Food Res. Suppl. , vol.1 , pp. 1-282
    • Singleton, V.L.1    Esau, P.2
  • 123
    • 0037433172 scopus 로고    scopus 로고
    • Sequestering ability of butylated hydrooxytoluene, propyl gallate, resveratrol, and vitamin C and E against ABTS, DPPH, and hydroxyl free radicals in chemical and biological systems
    • Soares, D. G., Andreazza, A. C. and Salvador, M. 2003. Sequestering ability of butylated hydrooxytoluene, propyl gallate, resveratrol, and vitamin C and E against ABTS, DPPH, and hydroxyl free radicals in chemical and biological systems. J. Agric. Food Chem., 51: 1077 - 1080.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 1077-1080
    • Soares, D.G.1    Andreazza, A.C.2    Salvador, M.3
  • 124
    • 0030760030 scopus 로고    scopus 로고
    • Wine as a biological fluid: History, production, and disease prevention
    • Soleas, G. J., Diamandis, E. P. and Goldberg, D. M. 1997. Wine as a biological fluid: History, production, and disease prevention. J. Clin. Lab. Anal., 11: 287 - 313.
    • (1997) J. Clin. Lab. Anal. , vol.11 , pp. 287-313
    • Soleas, G.J.1    Diamandis, E.P.2    Goldberg, D.M.3
  • 126
    • 0000334719 scopus 로고    scopus 로고
    • DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia
    • Sun, N. J., Woo, S. H., Cassady, J. M. and Snapka, R. M. 1998. DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia. J. Nat. Prod., 61: 362 - 366.
    • (1998) J. Nat. Prod. , vol.61 , pp. 362-366
    • Sun, N.J.1    Woo, S.H.2    Cassady, J.M.3    Snapka, R.M.4
  • 127
    • 0033042331 scopus 로고    scopus 로고
    • Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells
    • Surh, Y. J., Hurh, Y. J., Kang, J. Y., Lee, E., Kong, G. and Lee, S. J. 1999. Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells. Cancer Lett, 140: 1 - 10.
    • (1999) Cancer Lett , vol.140 , pp. 1-10
    • Surh, Y.J.1    Hurh, Y.J.2    Kang, J.Y.3    Lee, E.4    Kong, G.5    Lee, S.J.6
  • 128
    • 23844476731 scopus 로고    scopus 로고
    • Fascination with enzymes: The journey not the arrival matters
    • Talalay, P. A. 2005. Fascination with enzymes: The journey not the arrival matters. J. Biol. Chem., 280: 28829 - 28847.
    • (2005) J. Biol. Chem. , vol.280 , pp. 28829-28847
    • Talalay, P.A.1
  • 129
    • 34247282872 scopus 로고    scopus 로고
    • Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin
    • Tanigawa, S., Fujii, M. and Hou, D.-X. 2007. Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin. Free Radi. Bio. Medi., 42: 1690 - 1703.
    • (2007) Free Radi. Bio. Medi. , vol.42 , pp. 1690-1703
    • Tanigawa, S.1    Fujii, M.2    Hou, D.-X.3
  • 130
    • 0344962128 scopus 로고    scopus 로고
    • Inhibition of in-vitro human LDL oxidation by phenolic antioxidants from grapes and wines
    • Teissedre, P. L., Frankel, E. N., Waterhouse, A. L., Peleg, H. and German, J. B. 1996. Inhibition of in-vitro human LDL oxidation by phenolic antioxidants from grapes and wines. J. Sci. Food Agric., 70: 55 - 61.
    • (1996) J. Sci. Food Agric. , vol.70 , pp. 55-61
    • Teissedre, P.L.1    Frankel, E.N.2    Waterhouse, A.L.3    Peleg, H.4    German, J.B.5
  • 131
    • 0001269795 scopus 로고    scopus 로고
    • Resveratrol: Isomeric molar absorptivities and stability
    • Trela, B. C. and Waterhouse, A. L. 1996. Resveratrol: Isomeric molar absorptivities and stability. J. Agric. Food Chem., 44: 1253 - 1257.
    • (1996) J. Agric. Food Chem. , vol.44 , pp. 1253-1257
    • Trela, B.C.1    Waterhouse, A.L.2
  • 132
    • 0034490790 scopus 로고    scopus 로고
    • The role of anthocyanins as an antioxidant under oxidative stress in rats
    • Tsuda, T., Horio, F. and Osawa, T. 2000. The role of anthocyanins as an antioxidant under oxidative stress in rats. BioFactors, 13: 133 - 139.
    • (2000) BioFactors , vol.13 , pp. 133-139
    • Tsuda, T.1    Horio, F.2    Osawa, T.3
  • 133
    • 0025941984 scopus 로고
    • Inhibition of platelet aggregation by some flavonoids
    • Tzeng, S. H., Ko, W. C., Ko, F. N. and Teng, C. M. 1991. Inhibition of platelet aggregation by some flavonoids. Thromb Res, 64: 91 - 100.
    • (1991) Thromb Res , vol.64 , pp. 91-100
    • Tzeng, S.H.1    Ko, W.C.2    Ko, F.N.3    Teng, C.M.4
  • 134
    • 0023263456 scopus 로고
    • Condensed tannins scavenging active oxygen radicals
    • Uchida, S. 1980. Condensed tannins scavenging active oxygen radicals. Med. Sci. Res., 15: 831 - 832.
    • (1980) Med. Sci. Res. , vol.15 , pp. 831-832
    • Uchida, S.1
  • 135
    • 0035798831 scopus 로고    scopus 로고
    • Induction of human NAD(P)H:quinone oxidoreductase (NQO1) gene expression by the flavonol quercetin
    • Valerio, L. G. Jr., Kepa, J. K., Pickwell, G. V. and Quattrochi, L. C. 2001. Induction of human NAD(P)H:quinone oxidoreductase (NQO1) gene expression by the flavonol quercetin. Toxicol. Lett., 119: 49 - 57.
    • (2001) Toxicol. Lett. , vol.119 , pp. 49-57
    • Valerio Jr., L.G.1    Kepa, J.K.2    Pickwell, G.V.3    Quattrochi, L.C.4
  • 136
    • 80051634012 scopus 로고    scopus 로고
    • Resveratrol suppresses human colon cancer cell proliferation and induces apoptosis via targeting the pentose phosphate and the talin-FAK signaling pathways-A proteomic approach
    • Vanamala, J., Radhakrishnan, S., Reddivari, L., Bhat, V. B. and Ptitsyn, A. 2011. Resveratrol suppresses human colon cancer cell proliferation and induces apoptosis via targeting the pentose phosphate and the talin-FAK signaling pathways-A proteomic approach. Proteome Sci., 9 doi: 10.1186/1477-5956-9-49
    • (2011) Proteome Sci. , vol.9
    • Vanamala, J.1    Radhakrishnan, S.2    Reddivari, L.3    Bhat, V.B.4    Ptitsyn, A.5
  • 137
    • 77958518016 scopus 로고    scopus 로고
    • Biomedical effects of grape products
    • Vislocky, L. M. and Fernandez, M. L. 2010. Biomedical effects of grape products. Nutr. Rev., 68: 656 - 670.
    • (2010) Nutr. Rev. , vol.68 , pp. 656-670
    • Vislocky, L.M.1    Fernandez, M.L.2
  • 139
    • 0032986801 scopus 로고    scopus 로고
    • Antioxidant and antiinflammatory activites of anthocyanins and their aglycon, cyanidin, from tart cherries
    • Wang, K., Nair, M. G., Strasburg, G. M., Chang, Y.-C., Booren, A. M., Gray, J. I. and DeWitt, D. L. 1999. Antioxidant and antiinflammatory activites of anthocyanins and their aglycon, cyanidin, from tart cherries. J. Nat. Prod., 62: 294 - 296.
    • (1999) J. Nat. Prod. , vol.62 , pp. 294-296
    • Wang, K.1    Nair, M.G.2    Strasburg, G.M.3    Chang, Y.-C.4    Booren, A.M.5    Gray, J.I.6    DeWitt, D.L.7
  • 140
    • 0031000208 scopus 로고    scopus 로고
    • Functional antioxidant responsive elements
    • Wasserman, W. W. and Fahl, W. E. 1997. Functional antioxidant responsive elements. Proc. Natl. Acad. Sci. USA., 94: 5361 - 5366.
    • (1997) Proc. Natl. Acad. Sci. USA. , vol.94 , pp. 5361-5366
    • Wasserman, W.W.1    Fahl, W.E.2
  • 141
    • 82955207120 scopus 로고    scopus 로고
    • Pleiotropic benefit of monomeric and oligomeric flavanols on vascular health-A randomized controlled clinical pilot study
    • Weseler, A. R., Ruijters, E. J., Drittij-Reijnders, M. J., Reesink, K. D., Haenen, G. R. M. M. and Bast, A. 2011. Pleiotropic benefit of monomeric and oligomeric flavanols on vascular health-A randomized controlled clinical pilot study. PLoS One, 6: e28460
    • (2011) PLoS One , vol.6
    • Weseler, A.R.1    Ruijters, E.J.2    Drittij-Reijnders, M.J.3    Reesink, K.D.4    Haenen, G.R.M.M.5    Bast, A.6
  • 142
    • 0034900080 scopus 로고    scopus 로고
    • Downregulation of the cyclin D1/Cdk4 complex occurs during resveratrol-induced cell cycle arrest in colon cancer cell lines
    • Wolter, F., Akoglu, B., Clausnitzer, A. and Stein, J. 2001. Downregulation of the cyclin D1/Cdk4 complex occurs during resveratrol-induced cell cycle arrest in colon cancer cell lines. J. Nutr., 131: 2197 - 2203.
    • (2001) J. Nutr. , vol.131 , pp. 2197-2203
    • Wolter, F.1    Akoglu, B.2    Clausnitzer, A.3    Stein, J.4
  • 143
    • 0010839142 scopus 로고    scopus 로고
    • Anthocyanins. Ch. 11
    • In: Francis F. J., Lauro G. J., editors New York, New York,: Marcel Dekker, Inc
    • Wrolstad, R. E. 2000. " Anthocyanins. Ch. 11 ". In Natural Food Colorants, Edited by: Francis, F. J. and Lauro, G. J. 237 - 252. New York: Marcel Dekker, Inc.
    • (2000) Natural Food Colorants , pp. 237-252
    • Wrolstad, R.E.1
  • 144
    • 78851470003 scopus 로고    scopus 로고
    • Resveratrol: A cardioprotective substance
    • Wu, J. M. and Hsieh, T. C. 2011. Resveratrol: A cardioprotective substance. Ann. N Y Acad. Sci., 1215: 16 - 21.
    • (2011) Ann. N Y Acad. Sci. , vol.1215 , pp. 16-21
    • Wu, J.M.1    Hsieh, T.C.2
  • 146
    • 59649102647 scopus 로고    scopus 로고
    • Induction of phase II enzyme, quinone reductase, in murine hepatoma cells in vitro by grape extracts and selected phytochemicals
    • Yang, J. and Liu, R. H. 2009. Induction of phase II enzyme, quinone reductase, in murine hepatoma cells in vitro by grape extracts and selected phytochemicals. Food Chem., 114: 898 - 904.
    • (2009) Food Chem. , vol.114 , pp. 898-904
    • Yang, J.1    Liu, R.H.2
  • 147
    • 64449088061 scopus 로고    scopus 로고
    • Phytochemical profiles and antioxidant activities of wine grapes
    • Yang, J., Martinson, T. E. and Liu, R. H. 2009. Phytochemical profiles and antioxidant activities of wine grapes. Food Chem., 116: 332 - 339.
    • (2009) Food Chem. , vol.116 , pp. 332-339
    • Yang, J.1    Martinson, T.E.2    Liu, R.H.3
  • 148
    • 0029000906 scopus 로고
    • Antitumor promotion by phenolic antioxidants: Inhibition of AP-1 activity through induction of Fra expression
    • Yoshioka, K., Deng, T., Cavigelli, M. and Karin, M. 1995. Antitumor promotion by phenolic antioxidants: Inhibition of AP-1 activity through induction of Fra expression. Proc. Natl. Acad. Sci. USA., 92: 4972 - 4976.
    • (1995) Proc. Natl. Acad. Sci. USA. , vol.92 , pp. 4972-4976
    • Yoshioka, K.1    Deng, T.2    Cavigelli, M.3    Karin, M.4
  • 149
    • 84860456358 scopus 로고    scopus 로고
    • High-performance liquid chromatography-mass spectrometry and evaporative light-scattering detector to compare phenolic profiles of muscadine grapes
    • You, Q., Chen, F., Sharp, J. L., Wang, X., You, Y. and Zhang, C. 2012. High-performance liquid chromatography-mass spectrometry and evaporative light-scattering detector to compare phenolic profiles of muscadine grapes. J. Chromatogr. A., 1240: 96 - 103.
    • (2012) J. Chromatogr. A. , vol.1240 , pp. 96-103
    • You, Q.1    Chen, F.2    Sharp, J.L.3    Wang, X.4    You, Y.5    Zhang, C.6
  • 150
    • 84863267798 scopus 로고    scopus 로고
    • Cellular and molecular effects of resveratrol in health and disease
    • Yu, W., Fu, Y.-C. and Wang, W. 2011. Cellular and molecular effects of resveratrol in health and disease. J. Cellu. Biochem., 113: 752 - 759.
    • (2011) J. Cellu. Biochem. , vol.113 , pp. 752-759
    • Yu, W.1    Fu, Y.-C.2    Wang, W.3
  • 151
    • 0034948728 scopus 로고    scopus 로고
    • Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways
    • Yu, R., Hebbar, V., Kim, D. W., Mandlekar, S., Pezzuto, J. M. and Kong, A. N. 2001. Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways. Mol. Pharmacol., 60: 217 - 224.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 217-224
    • Yu, R.1    Hebbar, V.2    Kim, D.W.3    Mandlekar, S.4    Pezzuto, J.M.5    Kong, A.N.6
  • 152
    • 82955168301 scopus 로고    scopus 로고
    • Impact of apple and grape juice consumption on the antioxidant status in healthy subjects
    • Yuan, L. H., Meng, L. P., Ma, W. W., Xiao, Z. X., Zhu, X., Feng, J. F., Yu, H. and Xiao, R. 2011. Impact of apple and grape juice consumption on the antioxidant status in healthy subjects. Int. J. Food Sci. Nutr., 62: 844 - 850.
    • (2011) Int. J. Food Sci. Nutr. , vol.62 , pp. 844-850
    • Yuan, L.H.1    Meng, L.P.2    Ma, W.W.3    Xiao, Z.X.4    Zhu, X.5    Feng, J.F.6    Yu, H.7    Xiao, R.8
  • 153
    • 0027407231 scopus 로고
    • A case-control study of oral cancer in Beijing, People's Republic of China. Association with nutrient intakes, foods, and food groups
    • Zheng, T., Boyle, P., Willett, W. C., Hu, H., Dan, J., Evstifeeva, T. V., Niu, S. and MacMahon, B. 1993. A case-control study of oral cancer in Beijing, People's Republic of China. Association with nutrient intakes, foods, and food groups. Eur. J. Cancer Biol. Oral. Oncol., 29B: 45 - 55.
    • (1993) Eur. J. Cancer Biol. Oral. Oncol. , vol.29 B , pp. 45-55
    • Zheng, T.1    Boyle, P.2    Willett, W.C.3    Hu, H.4    Dan, J.5    Evstifeeva, T.V.6    Niu, S.7    MacMahon, B.8
  • 154
    • 69549097608 scopus 로고    scopus 로고
    • Type 2 diabetes and glycemic response to grapes or grape products
    • Zunino, S. 2009. Type 2 diabetes and glycemic response to grapes or grape products. J Nutr., 139: 1794S - 1800S.
    • (2009) J Nutr. , vol.139
    • Zunino, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.