Inhibition of Human Low-Density Lipoprotein Oxidation in Relation to Composition of Phenolic Antioxidants in Grapes (Vitis vinifera)

Journal of Agricultural and Food Chemistry

Volumn 45, Issue 5, 1997, Pages 1638-1643

  Meyer, Anne S ^a,b   Yi, Ock Sook ^a   Pearson, Debra A ^a   Waterhouse, Andrew L ^a   Frankel, Edwin N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Anthocyanins; Flavan 3 ols; Flavonoids; Flavonols; HPLC; Hydroxycinnamates; LDL oxidation

Indexed keywords

VITACEAE; VITIS SP.; VITIS VINIFERA;

EID: 0001479611     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf960721a     Document Type: Article

References (30)

1. Berry, D. A.; Lindgren, B. W. Statistics: Theory and methods, 2nd ed.; Duxbury Press at Wadsworth Publ. Co.: Belmont, CA, 1996; pp 608-609.
2. Bourzeix, M.; Weyland, D.; Heredia, N. A study of catechins and procyanidins of grape clusters, the wine and other by-products of the vine. Bull. O.I.V. 1986, 59, 1171-1254 (transl. from French).
3. Cheynier, V.; Trousdale, E. K.; Singleton, V. L.; Salgues, M. J.; Wylde, R. Characterization of 2-S-glutathionylcaftaric acid and its hydrolysis in relation to grape wines. J. Agric. Food Chem. 1986, 34, 217-221.
4. Cheynier, V.; Moutounet, M. Oxidative reactions of caffeic acid in model systems containing polyphenol oxidase. J. Agric. Food Chem. 1992, 40, 2038-2044.
5. Criqui, M. H.; Ringel, B. L. Does diet or alcohol explain the French paradox? Lancet 1994, 344, 1719-1723.
6. Frankel, E. N.; German, J. B.; Davis, P. A. Headspace gas chromatography to determine human low-density lipoprotein oxidation. Lipids 1992, 27, 1047-1051.
7. Frankel, E. N.; Kanner, J.; German, J. B.; Parks, E.; Kinsella, J. E. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. Lancet 1993, 341, 454-457.
8. Frankel, E. N.; Waterhouse, A. L.; Teissedre, P. L. Principal phenolic phytochemicals in selected California wines and their antioxidant activity in inhibiting oxidation of human low-density lipoproteins. J. Agric. Food Chem. 1995, 43, 890-894.
9. Hertog, M. G. L.; Feskens, E. J. M.; Hollman, P. C. H.; Katan, M. B.; Kromhout, D. Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen elderly study. Lancet 1993, 342, 1007-1011.
10. Hertog, M. G. L.; Kromhout, D.; Aravanis, C.; Blackburn, H.; Buzina, R.; Fidanza, F.; Giampaoli, S.; Jansen, A.; Menotti, A., Nedeljkovic, S.; Pekkarinen, M.; Simic, B. S.; Toshima, H.; Feskens, E. J. M.; Hollman, P. C. H.; Katan, M. B. Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study. Arch. Intern. Med. 1995, 155, 381-386.
11. Hollman, P. C. H.; de Vries, J. H. M.; van Leeuwen, S. D.; Mengelers, M. J. B.; Katan, M. B. Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. Am. J. Clin. Nutr. 1995, 62, 1276-1282.
12. Kanner, J.; Frankel, E.; Granit, R.; German, B.; Kinsella, J. E. Natural antioxidants in grapes and wines. J. Agric. Food Chem. 1994, 42, 64-69.
13. Kinsella, J. E.; Frankel, E.; German, B.; Kanner, J. Possible mechanisms for the protective role of antioxidants in wine and plant foods. Food Technol. 1993, 47, 85-89.
14. Knekt, P.; Järvinen, R.; Reunanen, A.; Maatela, J. Flavonoid intake and coronary mortality in Finland: A cohort study. Br. Med. J. 1996, 372, 478-481.
15. Lamuela-Raventos, R. M.; Waterhouse, A. L. A direct HPLC separation of wine phenolics. Am. J. Enol. Vitic. 1994, 45, 1-5.
16. Lee, C. Y.; Jaworski A. W. Identification of some phenolics in white grapes. Am. J. Enol. Vitic. 1990, 41, 87-89.
17. Montgomery, D. C. Design and analysis of experiments, 3rd ed.; John Wiley & Sons: New York, 1991; pp 102-103.
18. Nardini, M.; D'Aquino, M.; Tomassi, G.; Gentili, V.; Di Felice, M.; Scaccini, C. Inhibition of human low-density lipoprotein oxidation by caffeic acid and other hydroxycinnamic acid derivatives. Free Radical Biol. Med. 1995, 19, 541-552.
19. Orr, J. R.; Adamson, G. L.; Lindgren, F. T. Preparative ultracentrifugation and analytic ultracentrifugation of plasma lipoproteins. In Analysis of fats, oils and lipoproteins; Perkins, E. G., Ed.; American Oil Chemists' Society: Champaign, IL, 1991; pp 524-554.
20. Renaud, S.; de Lorgeril, M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 1992, 339, 1523-1526.
21. Santos-Buelga, C.; Fancia-Aricha, E. M.; Escribano-Bailon, M. T. Comparative flavan-3-ol composition of seeds from different grape varieties. Food Chem. 1995, 53, 197-201.
22. Singleton, V. L. Grape and wine phenolics: background and prospects. In Proceedings of University of California-Davis, Grape wine centennial symposium; Webb, A. D., Ed.; Department of Viticulture and Enology, University of California-Davis: Davis, CA, 1982; pp 215-227.
23. Singleton, V. L. Oxygen with phenols and related reactions in musts, wines, and model systems: Observations and practical implications. Am. J. Enol. Vitic. 1987, 38, 69-77.
24. Singleton, V. L.; Rossi, J. A. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am. J. Enol. Vitic. 1965, 16, 144-158.
25. Singleton, V. L.; Salgues, M.; Zaya, J.; Trousdale, E. Caftaric acid disappearance and conversion to products of enzymic oxidation in grape must and wine. Am. J. Enol. Vitic. 1985, 36, 50-56.
26. Somers, T. C.; Ziemelis, G. Spectral evaluation of total phenolic components in Vitis viifera: Grapes and wines. J. Sci. Food Agric. 1985, 36, 1275-1284.
27. Steinberg, D. Metabolism of lipoproteins and their role in the pathogenesis of atherosclerosis. Atheroscler. Rev. 1992, 18, 1-6.
28. Steinberg, D.; Parthasarathy, S.; Carew, T. E.; Khoo, J. C.; Witztum, J. L. Beyond cholesterol. Modification of lowdensity lipoproteins that increase its atherogenicity. N. Engl. J. Med. 1989, 320, 915-924.
29. Teissedre, P. L.; Frankel, E. N.; Waterhouse, A. L.; Peleg, H.; German, J. B. Inhibition of in vitro human LDL oxidation by phenolic antioxidants from grapes and wines. J. Sci. Food Agric. 1996, 70, 55-61.
30. Wang, H.; Cao, G.; Prior, R. L. Total antioxidant capacity of fruits. J. Agric. Food Chem. 1996, 44, 701-705.