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Volumn 29, Issue 2, 2011, Pages 380-391

Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma

Author keywords

Cardiac function; Chemoprevention; Diethylnitrosamine; Echocardiography; Hepatocarcinogenesis; Resveratrol

Indexed keywords

DIETHYLNITROSAMINE; RESVERATROL; CARDIOTOXIN; STILBENE DERIVATIVE;

EID: 79957444978     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-009-9332-7     Document Type: Article
Times cited : (35)

References (78)
  • 2
    • 0141491273 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • DOI 10.1016/S0140-6736(03)14964-1
    • Llovet JM, Burroughs A, Buix J (2003) Hepatocellular carcinoma. Lancet 362:1907-1917 (Pubitemid 37518510)
    • (2003) Lancet , vol.362 , Issue.9399 , pp. 1907-1917
    • Llovet, J.M.1    Burroughs, A.2    Bruix, J.3
  • 3
    • 7044231396 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Recent trends in the United States
    • DOI 10.1053/j.gastro.2004.09.013, PII S0016508504015926
    • El-Serag HB (2004) Hepatocellular carcinoma: recent trends in the United States. Gastroenterology 127:S27-S34 (Pubitemid 39423367)
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL.
    • El-Serag, H.B.1
  • 4
    • 67650385302 scopus 로고    scopus 로고
    • American Cancer Society, American Cancer Society, Atlanta
    • American Cancer Society (2009) Cancer facts and figures 2009. American Cancer Society, Atlanta
    • (2009) Cancer Facts and Figures 2009
  • 5
    • 0021680014 scopus 로고
    • Relevance of nitrosamines to human cancer
    • Bartsch H, Montesano R (1984) Relevance of nitrosamines to human cancer. Carcinogenesis 5:1381-1393 (Pubitemid 15218943)
    • (1984) Carcinogenesis , vol.5 , Issue.11 , pp. 1381-1393
    • Bartsch, H.1    Montesano, R.2
  • 7
    • 33746268320 scopus 로고    scopus 로고
    • Molecular pathways in hepatocellular carcinoma
    • DOI 10.1016/j.canlet.2005.08.031, PII S0304383505008037
    • Pang R, Tse E, Poon TP (2006) Molecular pathways in hepatocellular carcinoma. Cancer Lett 240:157-169 (Pubitemid 44093818)
    • (2006) Cancer Letters , vol.240 , Issue.2 , pp. 157-169
    • Pang, R.1    Tse, E.2    Poon, R.T.P.3
  • 8
    • 67650938576 scopus 로고    scopus 로고
    • Hepatocellular carcinoma-epidemiological trends and risk factors
    • Schütte K, Bornscein J, Malfertheiner P (2009) Hepatocellular carcinoma-epidemiological trends and risk factors. Dig Dis 27:80-92
    • (2009) Dig Dis , vol.27 , pp. 80-92
    • Schütte, K.1    Bornscein, J.2    Malfertheiner, P.3
  • 9
    • 46349101016 scopus 로고    scopus 로고
    • The influence of alcohol consumption and hepatitis B and C infections on the risk of liver cancer in Europe
    • Ribes J, Clèries R, Esteban L, Moreno V, Bosch FX (2008) The influence of alcohol consumption and hepatitis B and C infections on the risk of liver cancer in Europe. J Hepatol 49:233-242
    • (2008) J Hepatol , vol.49 , pp. 233-242
    • Ribes, J.1    Clèries, R.2    Esteban, L.3    Moreno, V.4    Bosch, F.X.5
  • 10
    • 0038049147 scopus 로고    scopus 로고
    • Translational strategies for cancer prevention in liver
    • DOI 10.1038/nrc1076
    • Kensler TW, Quian GS, Chen JG, Groopman JD (2003) Translational strategies for cancer prevention in liver. J Natl Cancer Inst 3:321-329 (Pubitemid 37328852)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.5 , pp. 321-329
    • Kensler, T.W.1    Qian, G.-S.2    Chen, J.-G.3    Groopman, J.D.4
  • 11
    • 0035702637 scopus 로고    scopus 로고
    • Chemoprevention of hepatocellular carcinoma: Concept, progress and perspectives
    • DOI 10.1046/j.1440-1746.2001.02634.x
    • Okuno M, Kojima S, Moriwaki H (2001) Chemoprevention of hepatocellular carcinoma: concept, progress and perspectives. J Gastroenterol Hepatol 16:1329-1335 (Pubitemid 34107398)
    • (2001) Journal of Gastroenterology and Hepatology , vol.16 , Issue.12 , pp. 1329-1335
    • Okuno, M.1    Kojima, S.2    Moriwaki, H.3
  • 12
    • 34548380363 scopus 로고    scopus 로고
    • Keap1 eye on the target: Chemoprevention of liver cancer
    • DOI 10.1111/j.1745-7254.2007.00688.x
    • Yates MS, Kensler TW (2007) Keap1 eye on the target: chemoprevention of liver cancer. Acta Pharmacol Sin 28:1331-1342 (Pubitemid 47366685)
    • (2007) Acta Pharmacologica Sinica , vol.28 , Issue.9 , pp. 1331-1342
    • Yates, M.S.1    Kensler, T.W.2
  • 13
    • 0037105738 scopus 로고    scopus 로고
    • Cancer chemoprevention science and practice
    • Lippman SM, Hong WK (2002) Cancer chemoprevention science and practice. Cancer Res 62:5119-5125
    • (2002) Cancer Res , vol.62 , pp. 5119-5125
    • Lippman, S.M.1    Hong, W.K.2
  • 15
    • 47549102103 scopus 로고    scopus 로고
    • Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trials
    • DOI 10.2174/092986708784221403
    • Naithani R, Huma LC, Moriarty RM, McCormick DL, Mehta RG (2008) Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trials. Curr Med Chem 15:1044-1071 (Pubitemid 352005717)
    • (2008) Current Medicinal Chemistry , vol.15 , Issue.11 , pp. 1044-1071
    • Naithani, R.1    Huma, L.C.2    Moriarty, R.M.3    McCormick, D.L.4    Mehta, R.G.5
  • 16
  • 17
    • 43549088782 scopus 로고    scopus 로고
    • Resveratrol: A multitargeted agent for age-associated chronic diseases
    • Harikumar KB, Aggarwal BB (2008) Resveratrol, a multitargeted agent for age associated chronic diseases. Cell cycle 7:1020-1037 (Pubitemid 351679835)
    • (2008) Cell Cycle , vol.7 , Issue.8 , pp. 1020-1037
    • Harikumar, K.B.1    Aggarwal, B.B.2
  • 18
    • 0034645693 scopus 로고    scopus 로고
    • Biological effects of resveratrol
    • Fremont L (2000) Biological effects of resveratrol. Life Sci 66:663-673
    • (2000) Life Sci , vol.66 , pp. 663-673
    • Fremont, L.1
  • 19
    • 0031839670 scopus 로고    scopus 로고
    • Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the 'French paradox'?
    • DOI 10.1530/eje.0.1380619
    • Kopp P (1998) Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the 'French paradox'? Eur J Endocrinol 138:619-620 (Pubitemid 28313808)
    • (1998) European Journal of Endocrinology , vol.138 , Issue.6 , pp. 619-620
    • Kopp, P.1
  • 20
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • DOI 10.1038/nrd2060, PII NRD2060
    • Baur JA, Sinclair DA (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5:493-506 (Pubitemid 44136961)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 21
    • 34547684362 scopus 로고    scopus 로고
    • Chemoprevention by resveratrol: Molecular mechanisms and therapeutic potential
    • Shankar S, Singh G, Srivastava RK (2007) Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential. Front Biosci 12:4839-4854
    • (2007) Front Biosci , vol.12 , pp. 4839-4854
    • Shankar, S.1    Singh, G.2    Srivastava, R.K.3
  • 22
    • 38649132291 scopus 로고    scopus 로고
    • Resveratrol and its analogs: Defense against cancer, coronary disease and neurodegenerative maladies or just a fad?
    • DOI 10.1016/j.mrrev.2007.08.004, PII S1383574207000324
    • Saiko P, Szakmary A, Jaeger W, Szekeres T (2008) Resveratrol and its analogs: defense against cancer, coronary disease and neurodegenerative maladies or just a fad? Mutat Res 658:68-94 (Pubitemid 351172881)
    • (2008) Mutation Research - Reviews in Mutation Research , vol.658 , Issue.1-2 , pp. 68-94
    • Saiko, P.1    Szakmary, A.2    Jaeger, W.3    Szekeres, T.4
  • 25
    • 46749136505 scopus 로고    scopus 로고
    • Resveratrol: One molecule, many targets
    • Pirola L, Fröjdö S (2008) Resveratrol: one molecule, many targets. IUBMB Life 60:323-332
    • (2008) IUBMB Life , vol.60 , pp. 323-332
    • Pirola, L.1    Fröjdö, S.2
  • 27
    • 51349132313 scopus 로고    scopus 로고
    • Cancer chemopreventive and therapeutic potential of resveratrol: Mechanistic perspectives
    • Kundu JK, Surh Y-J (2008) Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives. Cancer Lett 269:243-261
    • (2008) Cancer Lett , vol.269 , pp. 243-261
    • Kundu, J.K.1    Surh, Y.-J.2
  • 28
    • 67650297506 scopus 로고    scopus 로고
    • Cancer prevention and treatment with resveratrol: From rodent studies to clinical trials
    • Bishayee A (2009) Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials. Cancer Prev Res 2:409-418
    • (2009) Cancer Prev Res , vol.2 , pp. 409-418
    • Bishayee, A.1
  • 29
    • 62549154478 scopus 로고    scopus 로고
    • Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: Inhibition of cell proliferation and induction of apoptosis
    • Bishayee A, Dhir N (2009) Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. Chem-Biol Interact 179:131-144
    • (2009) Chem-Biol Interact , vol.179 , pp. 131-144
    • Bishayee, A.1    Dhir, N.2
  • 30
    • 65249164833 scopus 로고    scopus 로고
    • Resveratrol: A promising agent in promoting cardioprotection against coronary heart disease
    • Penumathsa SV, Maulik N (2009) Resveratrol: a promising agent in promoting cardioprotection against coronary heart disease. Can J Physiol Pharmacol 87:275-286
    • (2009) Can J Physiol Pharmacol , vol.87 , pp. 275-286
    • Penumathsa, S.V.1    Maulik, N.2
  • 31
    • 0032801975 scopus 로고    scopus 로고
    • The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury
    • DOI 10.1016/S0891-5849(99)00063-5, PII S0891584999000635
    • Ray PS, Maulik G, Cordis GA, Bertelli AA, Bertelli A, Das DK (1999) The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury. Free Radic Biol Med 27:160-169 (Pubitemid 29353096)
    • (1999) Free Radical Biology and Medicine , vol.27 , Issue.1-2 , pp. 160-169
    • Ray, P.S.1    Maulik, G.2    Cordis, G.A.3    Bertelli, A.A.E.4    Bertelli, A.5    Das, D.K.6
  • 34
    • 1342306855 scopus 로고    scopus 로고
    • Resveratrol protects myocardial ischemia-reperfusion injury through both NOdependent and NO-independent mechanisms
    • Hung LM, Su MJ, Chen JK (2004) Resveratrol protects myocardial ischemia-reperfusion injury through both NOdependent and NO-independent mechanisms. Free Radic Biol Med 36:774-781
    • (2004) Free Radic Biol Med , vol.36 , pp. 774-781
    • Hung, L.M.1    Su, M.J.2    Chen, J.K.3
  • 35
    • 0029981730 scopus 로고    scopus 로고
    • Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta
    • DOI 10.1016/0306-3623(95)02001-2
    • Chen CK, Pace-Asciak CR (1996) Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta. Gen Pharmacol 27:363-366 (Pubitemid 26129194)
    • (1996) General Pharmacology , vol.27 , Issue.2 , pp. 363-366
    • Chen, C.K.1    Pace-Asciak, C.R.2
  • 37
    • 34648830916 scopus 로고    scopus 로고
    • Anti-inflammatory responses of resveratrol
    • DOI 10.2174/187152807781696464
    • Das S, Das DK (2007) Anti-inflammatory responses of resveratrol. Inflamm Allergy Drug Targets 6:168-173 (Pubitemid 47455785)
    • (2007) Inflammation and Allergy - Drug Targets , vol.6 , Issue.3 , pp. 168-173
    • Das, S.1    Das, D.K.2
  • 39
    • 33749265695 scopus 로고    scopus 로고
    • Cardioprotective effect of resveratrol via HO-1 expression involves p38 map kinase and PI-3-kinase signaling, but does not involve NFκB
    • DOI 10.1080/10715760600833085, PII K4707753V2VQQ710, Polyphenols and Health
    • Das S, Fraga CG, Das DK (2006) Cardioprotective effect of resveratrol via HO-1 expression involves p38 map kinase and PI- 3-kinase signaling, but does not involve NFkappaB. Free Radic Res 40:1066-1075 (Pubitemid 44480547)
    • (2006) Free Radical Research , vol.40 , Issue.10 , pp. 1066-1075
    • Das, S.1    Fraga, C.G.2    Das, D.K.3
  • 40
    • 67349189553 scopus 로고    scopus 로고
    • Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose
    • Dudley J, Das S, Mukherjee S, Das DK (2009) Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose. J Nutr Biochem 20:443-452
    • (2009) J Nutr Biochem , vol.20 , pp. 443-452
    • Dudley, J.1    Das, S.2    Mukherjee, S.3    Das, D.K.4
  • 41
    • 31544468915 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in hepatocellular carcinoma
    • DOI 10.1016/j.ctrv.2005.10.004, PII S0305737205002124
    • Wu T (2006) Cyclooxygenase-2 in hepatocellular carcinoma. Cancer Treat Rev 32:28-44 (Pubitemid 43159775)
    • (2006) Cancer Treatment Reviews , vol.32 , Issue.1 , pp. 28-44
    • Wu, T.1
  • 42
  • 44
    • 0036014815 scopus 로고    scopus 로고
    • Rationale and feasibility of chemoprovention of hepatocellular carcinoma by cyclooxygenase-2 inhibitors
    • DOI 10.1067/mlc.2002.122281
    • Hu K-Q (2002) Rationale and feasibility of chemoprevention of hepatocellular carcinoma by cyclooxygenase-2 inhibitors. J Lab Clin Med 139:234-243 (Pubitemid 34557358)
    • (2002) Journal of Laboratory and Clinical Medicine , vol.139 , Issue.4 , pp. 234-243
    • Hu, K.-Q.1
  • 45
    • 0043073254 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Is there a potential for chemoprevention using cyclooxygenase-2 inhibitors?
    • DOI 10.1002/cncr.11576
    • Koga H (2003) Hepatocelluar carcinoma: is there a potential for chemoprevention using cyclooxygenase-2 inhibitors. Cancer 98:661-667 (Pubitemid 36959260)
    • (2003) Cancer , vol.98 , Issue.4 , pp. 661-667
    • Koga, H.1
  • 47
    • 33748480133 scopus 로고    scopus 로고
    • Cyclooxygenase in hepatocellular carcinoma
    • Cervello M, Montalto G (2006) Cyclooxygenase in hepatocellular carcinoma. World J Gastroenterol 12:5113-5121
    • (2006) World J Gastroenterol , vol.12 , pp. 5113-5121
    • Cervello, M.1    Montalto, G.2
  • 48
    • 60849093525 scopus 로고    scopus 로고
    • Cycloxygenase-2 (COX-2) in carcinogenesis and selective COX-2 inhibitors for chemoprevention in gastrointestinal cancers
    • Fujimura T, Ohta T, Oyama K, Miyashita T, Miwa K (2007) Cycloxygenase-2 (COX-2) in carcinogenesis and selective COX-2 inhibitors for chemoprevention in gastrointestinal cancers. J Gastrointest Cancer 38:78-82
    • (2007) J Gastrointest Cancer , vol.38 , pp. 78-82
    • Fujimura, T.1    Ohta, T.2    Oyama, K.3    Miyashita, T.4    Miwa, K.5
  • 49
    • 33750449699 scopus 로고    scopus 로고
    • Coxibs and cancer prevention
    • DOI 10.1097/00005344-200605001-00014, PII 0000534420060500100014
    • Yona D, Arber N (2004) Coxibs and cancer prevention. J Cardiovasc Pharmacol 47:S76-S81 (Pubitemid 44651790)
    • (2006) Journal of Cardiovascular Pharmacology , vol.47 , Issue.SUPPL. 1
    • Yona, D.1    Arber, N.2
  • 50
    • 33749482264 scopus 로고    scopus 로고
    • Resveratrol is rapidly metabolized in athymic (Nu/Nu) mice and does not inhibit human melanoma xenograft tumor growth
    • Niles RM, Cook CP, Meadows GG, Fu Y-M, McLaughlin JL, Rankin GO (2006) Resveratrol is rapidly metabolized in athymic (Nu/Nu) mice and does not inhibit human melanoma xenograft tumor growth. J Nutr 136:2542-2546 (Pubitemid 44521610)
    • (2006) Journal of Nutrition , vol.136 , Issue.10 , pp. 2542-2546
    • Niles, R.M.1    Cook, C.P.2    Meadows, G.G.3    Fu, Y.-M.4    McLaughlin, J.L.5    Rankin, G.O.6
  • 52
    • 0032618361 scopus 로고    scopus 로고
    • Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis
    • Bishayee A, Roy S, Chatterjee M (1999) Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis. Oncol Res 11:41-53
    • (1999) Oncol Res , vol.11 , pp. 41-53
    • Bishayee, A.1    Roy, S.2    Chatterjee, M.3
  • 53
    • 0033839715 scopus 로고    scopus 로고
    • Further evidence for chemopreventive potential of β-carotene against experimental carcinogenesis: Diethylnitrosamine-initiated and phenobarbital-promoted hepatocarcinogenesis is prevented more effectively by β-carotene than by retinoic acid
    • Bishayee A, Sarkar A, Chatterjee M (2000) Further evidence for chemopreventive potential of β-carotene against experimental hepatocarcinogenesis: diethylnitrosamine-initiated and phenobarbital promoted hepatocarcinogenesis is prevented more effectively by β-carotene than by retinoic acid. Nutr Cancer 37:89-98 (Pubitemid 30650672)
    • (2000) Nutrition and Cancer , vol.37 , Issue.1 , pp. 89-98
    • Bishayee, A.1    Sarkar, A.2    Chatterjee, M.3
  • 54
    • 0028990089 scopus 로고
    • Inhibition of altered liver cell foci and persistent nodule growth by vanadium during diethylnitrosamine-induced hepatocarcinogenesis in rats
    • Bishayee A, Chatterjee M (1995) Inhibition of altered liver cell foci and persistent nodule growth by vanadium during diethylnitrosamine-induced hepatocarcinogenesis in rats. Anticancer Res 15:455-462
    • (1995) Anticancer Res , vol.15 , pp. 455-462
    • Bishayee, A.1    Chatterjee, M.2
  • 56
    • 0018231715 scopus 로고
    • Recommendations regarding quantitation in M-mode echocardiography: Results of a survey of echocardiographic measurements
    • Sahn DJ, DeMaria A, Kisslo J, Weyman A (1978) Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 58:1072-1083 (Pubitemid 9091990)
    • (1978) Circulation , vol.58 , Issue.6 , pp. 1072-1083
    • Sahn, D.J.1    DeMaria, A.2    Kisslo, J.3    Weyman, A.4
  • 57
    • 0029024241 scopus 로고
    • Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital
    • Bishayee A, Chatterjee M (1995) Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital. Brit J Cancer 71:1214-1220
    • (1995) Brit J Cancer , vol.71 , pp. 1214-1220
    • Bishayee, A.1    Chatterjee, M.2
  • 58
    • 33845678662 scopus 로고    scopus 로고
    • Carcinogen-induced early molecular events and its implication in the initiation of chemical hepatocarcinogenesis in rats: Chemopreventive role of vanadium on this process
    • DOI 10.1016/j.bbadis.2006.10.019, PII S0925443906002225
    • Chakraborty T, Chatterjee A, Rana A, Dhachinamoorthi D, Kumar PA, Chatterjee M (2007) Carcinogen-induced early molecular events and its implication in the initiation of chemical hepatocarcinogenesis in rats: chemopreventive role of vanadium on this process. Biochim Biophys Acta 1772:48-59 (Pubitemid 44960731)
    • (2007) Biochimica et Biophysica Acta - Molecular Basis of Disease , vol.1772 , Issue.1 , pp. 48-59
    • Chakraborty, T.1    Chatterjee, A.2    Rana, A.3    Dhachinamoorthi, D.4    Kumar P, A.5    Chatterjee, M.6
  • 59
    • 9644254191 scopus 로고    scopus 로고
    • Application of comparative functional genomics to identify best-fit mouse models to study human cancer
    • DOI 10.1038/ng1481
    • Lee JS, Chu IS, Mikaelyan A, Calvisi DF, Heo J, Reddy JK, Thorgeirsson SS (2004) Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nat Genetics 36:1306-1311 (Pubitemid 39577940)
    • (2004) Nature Genetics , vol.36 , Issue.12 , pp. 1306-1311
    • Lee, J.-S.1    Chu, I.-S.2    Mikaelyan, A.3    Calvisi, D.F.4    Heo, J.5    Reddy, J.K.6    Thorgeirsson, S.S.7
  • 60
    • 0023124846 scopus 로고
    • Hepatocarcinogenesis: A dynamic cellular perspective
    • Farber E, Sarma DS (1987) Hepatocarcinogenesis: a dynamic cellular perspective. Lab Invest 56:4-22
    • (1987) Lab Invest , vol.56 , pp. 4-22
    • Farber, E.1    Sarma, D.S.2
  • 61
    • 0018955647 scopus 로고
    • The pathogenesis of rat liver cancer caused by chemical carcinogens
    • Williams GM (1980) The pathogenesis of rat liver cancer caused by chemical carcinogens. Biochim Biophys Acta 605:167-189 (Pubitemid 10044077)
    • (1980) Biochimica et Biophysica Acta , vol.605 , Issue.2 , pp. 167-189
    • Williams, G.M.1
  • 62
    • 33645075440 scopus 로고    scopus 로고
    • Chemopreventive properties of black raspberries in N- nitrosomethylbenzylamine- induced rat esophageal tumorigenesis: Downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and c-Jun
    • Chen T, Hwang H, Rose ME, Nines RG, Stoner GD (2006) Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine- induced rat esophageal tumorigenesis: downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and c-Jun. Cancer Res 66:2853-2859
    • (2006) Cancer Res , vol.66 , pp. 2853-2859
    • Chen, T.1    Hwang, H.2    Rose, M.E.3    Nines, R.G.4    Stoner, G.D.5
  • 63
    • 22844437949 scopus 로고    scopus 로고
    • Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: Implications for an improved chemotherapy of primary liver tumors
    • DOI 10.1111/j.1478-3231.2005.01118.x
    • Di Stefano G, Fiume L, Bolondi L, Lanza M, Pariali M, Chieco P (2005) Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumours. Liver Int 25:854-860 (Pubitemid 41038667)
    • (2005) Liver International , vol.25 , Issue.4 , pp. 854-860
    • Di Stefano, G.1    Fiume, L.2    Bolondi, L.3    Lanza, M.4    Pariali, M.5    Chieco, P.6
  • 66
    • 33746599012 scopus 로고    scopus 로고
    • Resveratrol, but not EGCG, in the diet suppresses DMBA-induced mammary cancer in rats
    • Whitsett T, Carpenter M, Lamartiniere CA (2006) Resveratrol, but not EGCG, in the diet suppresses DMBA-induced mammary cancer in rats. J Carcinog 5:15
    • (2006) J Carcinog , vol.5 , pp. 15
    • Whitsett, T.1    Carpenter, M.2    Lamartiniere, C.A.3
  • 68
    • 68049147267 scopus 로고    scopus 로고
    • Safety studies conducted on high-purity trans-resveratrol in experimental animals
    • Williams LD, Burdock GA, Edwards JA, Beck M, Bausch J (2009) Safety studies conducted on high-purity trans-resveratrol in experimental animals. Food Chem Toxicol 47:2170-2182
    • (2009) Food Chem Toxicol , vol.47 , pp. 2170-2182
    • Williams, L.D.1    Burdock, G.A.2    Edwards, J.A.3    Beck, M.4    Bausch, J.5
  • 69
    • 0034707105 scopus 로고    scopus 로고
    • Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
    • Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B et al (2000) Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. N Eng J Med 343:1520-1528
    • (2000) N Eng J Med , vol.343 , pp. 1520-1528
    • Bombardier, C.1    Laine, L.2    Reicin, A.3    Shapiro, D.4    Burgos-Vargas, R.5    Davis, B.6
  • 70
    • 2542570187 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 inhibitors versus non-selective non-steroidal anti-inflammatory drugs and congestive heart failure outcomes in elderly patients: A population-based cohort study
    • DOI 10.1016/S0140-6736(04)16299-5, PII S0140673604162995
    • Mamdani M, Juurlink DN, Lee DS, Rochon PA, Kopp A, Naglie G et al (2004) Cyclo-oxygenase-2 inhibitors versus non-selective non-steroidal anti-inflammatory drugs and congestive heart failure outcomes in elderly patients: a population-based cohort study. Lancet 363:1751-1756 (Pubitemid 38698377)
    • (2004) Lancet , vol.363 , Issue.9423 , pp. 1751-1756
    • Mamdani, M.1    Juurlink, D.N.2    Lee, D.S.3    Rochon, P.A.4    Kopp, A.5    Naglie, G.6    Austin, P.C.7    Laupacis, A.8    Stukel, T.A.9
  • 71
    • 2442493150 scopus 로고    scopus 로고
    • Relationship between Selective Cyclooxygenase-2 Inhibitors and Acute Myocardial Infarction in Older Adults
    • DOI 10.1161/01.CIR.0000127578.21885.3E
    • Solomon DH, Schneeweiss S, Glynn RJ, Kiyota Y, Lenin R, Mogun H (2004) Relationship between selective cyclooxygenase- 2 inhibitors and acute myocardial infarction in older adults. Circulation 109:2068-2073 (Pubitemid 38620213)
    • (2004) Circulation , vol.109 , Issue.17 , pp. 2068-2073
    • Solomon, D.H.1    Schneeweiss, S.2    Glynn, R.J.3    Kiyota, Y.4    Levin, R.5    Mogun, H.6    Avorn, J.7
  • 75
    • 49549114451 scopus 로고    scopus 로고
    • Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats
    • Lin JF, Lin SM, Chih CL, Nien MW, Su HH, Hu BR, Huang SS, Tsai SK (2008) Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats. Life Sci 89:313-317
    • (2008) Life Sci , vol.89 , pp. 313-317
    • Lin, J.F.1    Lin, S.M.2    Chih, C.L.3    Nien, M.W.4    Su, H.H.5    Hu, B.R.6    Huang, S.S.7    Tsai, S.K.8
  • 78
    • 61849166733 scopus 로고    scopus 로고
    • Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage
    • Tatlidede E, Sehirli O, Velioǧlu-Oǧünc A, Cetinel S, Yeǧen BC, Yarat A et al (2009) Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage. Free Radic Res 43:195-205
    • (2009) Free Radic Res , vol.43 , pp. 195-205
    • Tatlidede, E.1    Sehirli, O.2    Velioǧlu-Oǧünc, A.3    Cetinel, S.4    Yeǧen, B.C.5    Yarat, A.6


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