Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice

General Pharmacology

Volumn 30, Issue 5, 1998, Pages 771-776

  Bian, Jing Tan ^a   Bhargava, Hemendra N ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

carotene; 12 O tetradecanoylphorbol 13 acetate (TPA); DNA fragmentation; Grape sed proanthocyanidin extract; Lipid peroxidation; Oxidative stress; Swiss Webster mice; Vitamin C; Vitamin E succinate; Zinc L methionine

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; PROANTHOCYANIDIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN HOMOGENATE; BRAIN INJURY; BRAIN METABOLISM; BRAIN TISSUE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DOSE RESPONSE; DRUG EFFECT; FEMALE; GRAPE; LIPID BRAIN LEVEL; LIPID PEROXIDATION; LIVER INJURY; LIVER METABOLISM; NONHUMAN; OXIDATIVE STRESS; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; TISSUE INJURY;

ANIMALS; ANTHOCYANINS; ANTIOXIDANTS; BRAIN; DNA FRAGMENTATION; FEMALE; LIPID PEROXIDATION; LIVER; MACROPHAGE ACTIVATION; MICE; PROANTHOCYANIDINS; REACTIVE OXYGEN SPECIES; ROSALES; TETRADECANOYLPHORBOL ACETATE;

EID: 0345215163     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(97)00332-7     Document Type: Article

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