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Volumn 113, Issue 3, 2012, Pages 752-759

Cellular and molecular effects of resveratrol in health and disease

Author keywords

Aging; Cellular Effect; P53; Resveretrol; Signal Transduction Pathway; Sirt1

Indexed keywords

ENDOTHELIN 1; RESVERATROL; SIRTUIN;

EID: 84863267798     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23431     Document Type: Review
Times cited : (163)

References (99)
  • 1
    • 33747886389 scopus 로고    scopus 로고
    • Resveratrol-A boon for treating Alzheimer's disease?
    • DOI 10.1016/j.brainresrev.2006.04.004, PII S0165017306000178
    • Anekonda TS. 2006. Resveratrol-a boon for treating Alzheimer's disease? Brain Res Rev 52: 316-326. (Pubitemid 44291807)
    • (2006) Brain Research Reviews , vol.52 , Issue.2 , pp. 316-326
    • Anekonda, T.S.1
  • 2
    • 0028861236 scopus 로고
    • Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis
    • Arend WP, Dayer JM. 1995. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis. Arthritis Rheum 38: 151-160.
    • (1995) Arthritis Rheum , vol.38 , pp. 151-160
    • Arend, W.P.1    Dayer, J.M.2
  • 3
    • 75649091175 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo
    • Bai Y, Mao QQ, Qin J, et al. 2010. Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo. Cancer Sci 101: 488-493.
    • (2010) Cancer Sci , vol.101 , pp. 488-493
    • Bai, Y.1    Mao, Q.Q.2    Qin, J.3
  • 4
    • 77952479612 scopus 로고    scopus 로고
    • Modulation of Akt and ERK1/2 pathways by resveratrol in chronic myelogenous leukemia (CML) cells results in the downregulation of Hsp70
    • Banerjee Mustafi S, Chakraborty PK, Raha S. 2010. Modulation of Akt and ERK1/2 pathways by resveratrol in chronic myelogenous leukemia (CML) cells results in the downregulation of Hsp70. PLoS One 5: e8719.
    • (2010) PLoS One , vol.5
    • Banerjee Mustafi, S.1    Chakraborty, P.K.2    Raha, S.3
  • 5
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • DOI 10.1038/nrd2060, PII NRD2060
    • Baur JA, Sinclair DA. 2006. Therapeutic potential of resveratrol: The in vivo evidence. Nat Rev Drug Discov 5: 493-506. (Pubitemid 44136961)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 6
    • 0035201910 scopus 로고    scopus 로고
    • Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women
    • Bhavnani BR, Cecutti A, Gerulath A, et al. 2001. Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women. Menopause 8: 408-419. (Pubitemid 33111576)
    • (2001) Menopause , vol.8 , Issue.6 , pp. 408-419
    • Bhavnani, B.R.1    Cecutti, A.2    Gerulath, A.3    Woolever, A.C.4    Berco, M.5
  • 7
    • 18144417435 scopus 로고    scopus 로고
    • Resveratrol, an extract of red wine, inhibits lipopolysaccharide induced airway neutrophilia and inflammatory mediators through an NF-kappaB-independent mechanism
    • Birrell MA, McCluskie K, Wong S, et al. 2005. Resveratrol, an extract of red wine, inhibits lipopolysaccharide induced airway neutrophilia and inflammatory mediators through an NF-kappaB-independent mechanism. FASEB J 19: 840-851.
    • (2005) FASEB J , vol.19 , pp. 840-851
    • Birrell, M.A.1    McCluskie, K.2    Wong, S.3
  • 8
    • 58849158388 scopus 로고    scopus 로고
    • How does SIRT1 affect metabolism senescence and cancer?
    • Brooks CL, Gu W. 2009. How does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer 9: 123-128.
    • (2009) Nat Rev Cancer , vol.9 , pp. 123-128
    • Brooks, C.L.1    Gu, W.2
  • 9
    • 0029617952 scopus 로고
    • Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-α antibody with the interleukin-1 receptor antagonist
    • Butler DM, Maini RN, Feldmann M, et al. 1995. Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonist. Eur Cytokine Netw 6: 225-230. (Pubitemid 26018294)
    • (1995) European Cytokine Network , vol.6 , Issue.4 , pp. 225-230
    • Butler, D.M.1    Maini, R.N.2    Feldmann, M.3    Brennan, F.M.4
  • 10
    • 0242322744 scopus 로고    scopus 로고
    • Effect of resveratrol on some activities of isolated and in whole blood human neutrophils
    • Cavallaro A, Ainis T, Bottari C, et al. 2003. Effect of resveratrol on some activities of isolated and in whole blood human neutrophils. Physiol Res 52: 555-562. (Pubitemid 37345641)
    • (2003) Physiological Research , vol.52 , Issue.5 , pp. 555-562
    • Cavallaro, A.1    Ainis, T.2    Bottari, C.3    Fimiani, V.4
  • 11
    • 20344396620 scopus 로고    scopus 로고
    • Resveratrol inhibits angiotensin II-induced endothelin-1 gene expression and subsequent proliferation in rat aortic smooth muscle cells
    • Chao HH, Juan SH, Liu JC, et al. 2005. Resveratrol inhibits angiotensin II-induced endothelin-1 gene expression and subsequent proliferation in rat aortic smooth muscle cells. Eur J Pharmacol 515: 1-9.
    • (2005) Eur J Pharmacol , vol.515 , pp. 1-9
    • Chao, H.H.1    Juan, S.H.2    Liu, J.C.3
  • 12
    • 78049275832 scopus 로고    scopus 로고
    • Red wine may be used in the therapy of myocarditis
    • Chen CJ, Yu W, Wang W. 2010. Red wine may be used in the therapy of myocarditis. J Cell Biochem 111: 808-810.
    • (2010) J Cell Biochem , vol.111 , pp. 808-810
    • Chen, C.J.1    Yu, W.2    Wang, W.3
  • 13
    • 57749197168 scopus 로고    scopus 로고
    • Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway
    • Chen CJ, Yu W, Fu YC, et al. 2009. Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway. Biochem Biophys Res Commun 378: 389-393.
    • (2009) Biochem Biophys Res Commun , vol.378 , pp. 389-393
    • Chen, C.J.1    Yu, W.2    Fu, Y.C.3
  • 14
    • 6444222048 scopus 로고    scopus 로고
    • Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells
    • Chen ZH, Hurh YJ, Na HK, et al. 2004. Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells. Carcinogenesis 25: 2005-2013.
    • (2004) Carcinogenesis , vol.25 , pp. 2005-2013
    • Zh, C.1    Hurh, Y.J.2    Na, H.K.3
  • 15
    • 70349212203 scopus 로고    scopus 로고
    • Interactions of gallic acid, resveratrol, quercetin and aspirin at the platelet cyclooxygenase-1 level Functional and modelling studies
    • Crescente M, Jessen G, Momi S, et al. 2009. Interactions of gallic acid, resveratrol, quercetin and aspirin at the platelet cyclooxygenase-1 level. Functional and modelling studies. Thromb Haemost 102: 336-346.
    • (2009) Thromb Haemost , vol.102 , pp. 336-346
    • Crescente, M.1    Jessen, G.2    Momi, S.3
  • 16
    • 76449099412 scopus 로고    scopus 로고
    • Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: Inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis
    • Csaki C, Mobasheri A, Shakibaei M. 2009. Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: Inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis. Arthritis Res Ther 11: R165.
    • (2009) Arthritis Res Ther , vol.11
    • Csaki, C.1    Mobasheri, A.2    Shakibaei, M.3
  • 17
    • 2942733214 scopus 로고    scopus 로고
    • Role of endothelial dysfunction in atherosclerosis
    • Davignon J, Ganz P. 2004. Role of endothelial dysfunction in atherosclerosis. Circulation 109: III27-III32. (Pubitemid 38786440)
    • (2004) Circulation , vol.109 , Issue.SUPPL.23
    • Davignon, J.1    Ganz, P.2
  • 18
    • 20344407841 scopus 로고    scopus 로고
    • Resveratrol as an anti-inflammatory and anti-aging agent: Mechanisms and clinical implications
    • DOI 10.1002/mnfr.200500022
    • de la Lastra CA, Villegas I. 2005. Resveratrol as an anti-inflammatory and anti-aging agent: Mechanisms and clinical implications. Mol Nutr Food Res 49: 405-430. (Pubitemid 40780389)
    • (2005) Molecular Nutrition and Food Research , vol.49 , Issue.5 , pp. 405-430
    • De La Lastra, C.A.1    Villegas, I.2
  • 21
    • 5644283296 scopus 로고    scopus 로고
    • Role of chemopreventive agents in cancer therapy
    • DOI 10.1016/j.canlet.2004.07.013, PII S0304383504005464
    • Dorai T, Aggarwal BB. 2004. Role of chemopreventive agents in cancer therapy. Cancer Lett 215: 129-140. (Pubitemid 39370030)
    • (2004) Cancer Letters , vol.215 , Issue.2 , pp. 129-140
    • Dorai, T.1    Aggarwal, B.B.2
  • 22
    • 0032911668 scopus 로고    scopus 로고
    • Resveratrol inhibits MAPK activity and nuclear translocation in coronary artery smooth muscle: Reversal of endothelin-1 stimulatory effects
    • DOI 10.1016/S0014-5793(99)00541-4, PII S0014579399005414
    • El-Mowafy AM, White RE. 1999. Resveratrol inhibits MAPK activity and nuclear translocation in coronary artery smooth muscle: Reversal of endothelin-1 stimulatory effects. FEBS Lett 451: 63-67. (Pubitemid 29236173)
    • (1999) FEBS Letters , vol.451 , Issue.1 , pp. 63-67
    • El-Mowafy, A.M.1    White, R.E.2
  • 24
    • 57349153327 scopus 로고    scopus 로고
    • Beneficial effects of resveratrol on atherosclerosis
    • Fan E, Zhang L, Jiang S, et al. 2008. Beneficial effects of resveratrol on atherosclerosis. J Med Food 11: 610-614.
    • (2008) J Med Food , vol.11 , pp. 610-614
    • Fan, E.1    Zhang, L.2    Jiang, S.3
  • 25
    • 0030661964 scopus 로고    scopus 로고
    • Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests
    • DOI 10.1016/S0024-3205(97)00883-7, PII S0024320597008837
    • Fauconneau B, Waffo-Teguo P, Huguet F, et al. 1997. Comparative study of radical scavenger and antioxidant properties of phenolic compounds from vitis vinifera cell cultures using in vitro tests. Life Sci 61: 2103-2110. (Pubitemid 27478837)
    • (1997) Life Sciences , vol.61 , Issue.21 , pp. 2103-2110
    • Fauconneau, B.1    Waffo-Teguo, P.2    Huguet, F.3    Barrier, L.4    Decendit, A.5    Merillon, J.-M.6
  • 26
    • 0036843624 scopus 로고    scopus 로고
    • Effects of resveratrol and ethanol on production of pro-inflammatory factors from endotoxin-activated murine macrophages
    • Feng YH, Zou JP, Li XY. 2002. Effects of resveratrol and ethanol on production of pro-inflammatory factors from endotoxin-activated murine macrophages. Acta Pharmacol 23: 1002-1006.
    • (2002) Acta Pharmacol , vol.23 , pp. 1002-1006
    • Feng, Y.H.1    Zou, J.P.2    Li, X.Y.3
  • 27
    • 0034645693 scopus 로고    scopus 로고
    • Biological effects of resveratrol
    • Frémont L. 2000. Biological effects of resveratrol. Life Sci 66: 663-673.
    • (2000) Life Sci , vol.66 , pp. 663-673
    • Frémont, L.1
  • 29
    • 77954090603 scopus 로고    scopus 로고
    • Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant B16 melanoma
    • Gatouillat G, Balasse E, Joseph-Pietras D, et al. 2010. Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant B16 melanoma. J Cell Biochem 110: 893-902.
    • (2010) J Cell Biochem , vol.110 , pp. 893-902
    • Gatouillat, G.1    Balasse, E.2    Joseph-Pietras, D.3
  • 30
    • 4644309893 scopus 로고    scopus 로고
    • Mechanisms of cardiovascular protection by resveratrol
    • DOI 10.1089/jmf.2004.7.290
    • Hao HD, He LR. 2004. Mechanisms of cardiovascular protection by resveratrol. J Med Food 7: 290-298. (Pubitemid 39299486)
    • (2004) Journal of Medicinal Food , vol.7 , Issue.3 , pp. 290-298
    • Hao, H.D.1    He, L.R.2
  • 31
    • 0033152949 scopus 로고    scopus 로고
    • 1
    • Hsieh TC, Juan G, Darzynkiewicz Z, et al. 1999. Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21WAF1/CIP1, and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2. Cancer Res 59: 2596-2601. (Pubitemid 29269105)
    • (1999) Cancer Research , vol.59 , Issue.11 , pp. 2596-2601
    • Hsieh, T.-C.1    Juan, G.2    Darzynkiewicz, Z.3    Wu, J.M.4
  • 32
    • 79961092644 scopus 로고    scopus 로고
    • Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice
    • Jackson JR, Ryan MJ, Alway SE. 2011. Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice. J Gerontol A Biol Sci Med Sci 66: 751-764.
    • (2011) J Gerontol A Biol Sci Med Sci , vol.66 , pp. 751-764
    • Jackson, J.R.1    Ryan, M.J.2    Alway, S.E.3
  • 33
    • 0035922171 scopus 로고    scopus 로고
    • Protective effects of resveratrol on hydrogen peroxide-induced apoptosis in rat pheochromocytoma (PC12) cells
    • Jang JH, Surh YJ. 2001. Protective effects of resveratrol on hydrogen peroxide-induced apoptosis in rat pheochromocytoma (PC12) cells. Mutat Res 496: 181-190.
    • (2001) Mutat Res , vol.496 , pp. 181-190
    • Jang, J.H.1    Surh, Y.J.2
  • 35
    • 76849112501 scopus 로고    scopus 로고
    • Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells
    • Jiang H, Shang X, Wu H, et al. 2010. Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells. Neurochem Res 35: 152-161.
    • (2010) Neurochem Res , vol.35 , pp. 152-161
    • Jiang, H.1    Shang, X.2    Wu, H.3
  • 36
    • 56149119401 scopus 로고    scopus 로고
    • Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats
    • Jin F, Wu Q, Lu YF, et al. 2008. Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats. Eur J Pharmacol 600: 78-82.
    • (2008) Eur J Pharmacol , vol.600 , pp. 78-82
    • Jin, F.1    Wu, Q.2    Lu, Y.F.3
  • 37
    • 77952375084 scopus 로고    scopus 로고
    • Resveratrol ameliorates vasculopathy in STZ-induced diabetic rats: Role of AGE-RAGE signalling
    • Jing YH, Chen KH, Yang SH, et al. 2010. Resveratrol ameliorates vasculopathy in STZ-induced diabetic rats: Role of AGE-RAGE signalling. Diabetes Metab Res Rev 26: 212-222.
    • (2010) Diabetes Metab Res Rev , vol.26 , pp. 212-222
    • Jing, Y.H.1    Chen, K.H.2    Yang, S.H.3
  • 38
    • 77449099964 scopus 로고    scopus 로고
    • Resveratrol enhances p53 acetylation and apoptosis in prostate cancer by inhibiting MTA1/NuRD complex
    • Kai L, Samuel SK, Levenson AS. 2010. Resveratrol enhances p53 acetylation and apoptosis in prostate cancer by inhibiting MTA1/NuRD complex. Int J Cancer 126: 1538-1548.
    • (2010) Int J Cancer , vol.126 , pp. 1538-1548
    • Kai, L.1    Samuel, S.K.2    Levenson, A.S.3
  • 39
    • 77953536163 scopus 로고    scopus 로고
    • Resveratrol modulates adipokine expression and improves insulin sensitivity in adipocytes: Relative to inhibition of inflammatory responses
    • Kang L, Heng W, Yuan A, et al. 2010. Resveratrol modulates adipokine expression and improves insulin sensitivity in adipocytes: Relative to inhibition of inflammatory responses. Biochimie 92: 789-796.
    • (2010) Biochimie , vol.92 , pp. 789-796
    • Kang, L.1    Heng, W.2    Yuan, A.3
  • 40
    • 63349108526 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms of resveratrol in activated HMC-1cells: Pivotal roles of NF-kappaB and MAPK
    • Kang OH, Jang HJ, Chae HS, et al. 2009. Anti-inflammatory mechanisms of resveratrol in activated HMC-1cells: Pivotal roles of NF-kappaB and MAPK. Pharmacol Res 59: 330-337.
    • (2009) Pharmacol Res , vol.59 , pp. 330-337
    • Kang, O.H.1    Jang, H.J.2    Chae, H.S.3
  • 43
    • 60249098801 scopus 로고    scopus 로고
    • Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease
    • Karuppagounder SS, Pinto JT, Xu H, et al. 2009. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem Int 54: 111-118.
    • (2009) Neurochem Int , vol.54 , pp. 111-118
    • Karuppagounder, S.S.1    Pinto, J.T.2    Xu, H.3
  • 44
    • 77950594327 scopus 로고    scopus 로고
    • Resveratrol attenuates 6-hydroxydopamine- induced oxidative damage and dopamine depletion in rat model of Parkinson's disease
    • Khan MM, Ahmad A, Ishrat T, et al. 2010. Resveratrol attenuates 6-hydroxydopamine- induced oxidative damage and dopamine depletion in rat model of Parkinson's disease. Brain Res 1328: 139-151.
    • (2010) Brain Res , vol.1328 , pp. 139-151
    • Khan, M.M.1    Ahmad, A.2    Ishrat, T.3
  • 46
    • 77954268849 scopus 로고    scopus 로고
    • Resveratrol inhibits neuronal apoptosis and elevated Ca2+/calmodulin- dependent protein kinase II activity in diabetic mouse retina
    • Kim YH, Kim YS, Kang SS, et al. 2010. Resveratrol inhibits neuronal apoptosis and elevated Ca2+/calmodulin-dependent protein kinase II activity in diabetic mouse retina. Diabetes 59: 1825-1835.
    • (2010) Diabetes , vol.59 , pp. 1825-1835
    • Kim, Y.H.1    Kim, Y.S.2    Kang, S.S.3
  • 47
    • 0034926855 scopus 로고    scopus 로고
    • Endothelial function and coronary artery disease
    • DOI 10.1097/00041433-200108000-00003
    • Kinlay S, Libby P, Ganz P. 2001. Endothelial function and coronary artery disease. Curr Opin Lipidol 12: 383-389. (Pubitemid 32675498)
    • (2001) Current Opinion in Lipidology , vol.12 , Issue.4 , pp. 383-389
    • Kinlay, S.1    Libby, P.2    Ganz, P.3
  • 48
    • 0036381118 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 and inducible nitric oxide synthase in pancreatic cancer
    • Kong G, Kim EK, Kim WS, et al. 2002. Role of cyclooxygenase-2 and inducible nitric oxide synthase in pancreatic cancer. J Gastroenterol Hepatol 17: 914-921.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 914-921
    • Kong, G.1    Kim, E.K.2    Kim, W.S.3
  • 50
    • 77951934363 scopus 로고    scopus 로고
    • Resveratrol-mediated reversal of doxorubicin resistance in acute myeloid leukemia cells via downregulation of MRP1 expression
    • Kweon SH, Song JH, Kim TS. 2010. Resveratrol-mediated reversal of doxorubicin resistance in acute myeloid leukemia cells via downregulation of MRP1 expression. Biochem Biophys Res Commun 395: 104-110.
    • (2010) Biochem Biophys Res Commun , vol.395 , pp. 104-110
    • Kweon, S.H.1    Song, J.H.2    Kim, T.S.3
  • 52
    • 2642559707 scopus 로고    scopus 로고
    • Effects of cis-resveratrol on inflammatory murine macrophages: Antioxidant activity and down-regulation of inflammatory genes
    • DOI 10.1189/jlb.1103561
    • Leiro J, Alvarez E, Arranz JA, et al. 2004. Effects of cis-resveratrol on inflammatory murine macrophages: Antioxidant activity and down- regulation of inflammatory genes. J Leukoc Biol 75: 1156-1165. (Pubitemid 38720660)
    • (2004) Journal of Leukocyte Biology , vol.75 , Issue.6 , pp. 1156-1165
    • Leiro, J.1    Alvarez, E.2    Arranz, J.A.3    Laguna, R.4    Uriarte, E.5    Orallo, F.6
  • 53
    • 72949115257 scopus 로고    scopus 로고
    • Implication of unfolded protein response in resveratrol-induced inhibition of K562 cell proliferation
    • Liu BQ, Gao YY, Niu XF, et al. 2010. Implication of unfolded protein response in resveratrol-induced inhibition of K562 cell proliferation. Biochem Biophys Res Commun 391: 778-782.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 778-782
    • Liu, B.Q.1    Gao, Y.Y.2    Niu, X.F.3
  • 54
    • 0347479294 scopus 로고    scopus 로고
    • Inhibition of cyclic strain-induced endothelin-1 gene expression by resveratrol
    • DOI 10.1161/01.HYP.0000103162.76220.51
    • Liu JC, Chen JJ, Chan P, et al. 2003. Inhibition of cyclic strain-induced endothelin-1 gene expression by resveratrol. Hypertension 42: 1198-1205. (Pubitemid 37549077)
    • (2003) Hypertension , vol.42 , Issue.6 , pp. 1198-1205
    • Liu, J.-C.1    Chen, J.-J.2    Chan, P.3    Cheng, C.-F.4    Cheng, T.-H.5
  • 55
    • 0242662063 scopus 로고    scopus 로고
    • Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: Effect on nitrosative and oxidative stress derived from microglial cells
    • DOI 10.1016/j.niox.2003.09.005
    • Lorenz P, Roychowdhury S, Engelmann M, et al. 2003. Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: Effect on nitrosative and oxidative stress derived from microglial cells. Nitric Oxide 9: 64-76. (Pubitemid 37386375)
    • (2003) Nitric Oxide - Biology and Chemistry , vol.9 , Issue.2 , pp. 64-76
    • Lorenz, P.1    Roychowdhury, S.2    Engelmann, M.3    Wolf, G.4    Horn, T.F.W.5
  • 56
    • 0034660659 scopus 로고    scopus 로고
    • Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-κB, activator protein-1, and apoptosis: Potential role of reactive oxygen intermediates and lipid peroxidation
    • Manna SK, Mukhopadhyay A, Aggarwal BB. 2000. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: Potential role of reactive oxygen intermediates and lipid peroxidation. J Immunol 164: 6509-6519. (Pubitemid 30408836)
    • (2000) Journal of Immunology , vol.164 , Issue.12 , pp. 6509-6519
    • Manna, S.K.1    Mukhopadhyay, A.2    Aggarwal, B.B.3
  • 57
    • 27844497059 scopus 로고    scopus 로고
    • Resveratrol promotes clearance of Alzheimer's disease amyloid-β peptides
    • DOI 10.1074/jbc.M508246200
    • Marambaud P, Zhao H, Davies P. 2005. Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J Biol Chem 280: 37377-37382. (Pubitemid 41642343)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.45 , pp. 37377-37382
    • Marambaud, P.1    Zhao, H.2    Davies, P.3
  • 58
    • 47849132642 scopus 로고    scopus 로고
    • Resveratrol in prevention and treatment of common clinical conditions of aging
    • Markus MA, Morris BJ. 2008. Resveratrol in prevention and treatment of common clinical conditions of aging. Clin Interv Aging 3: 331-339. (Pubitemid 352037871)
    • (2008) Clinical Interventions in Aging , vol.3 , Issue.2 , pp. 331-339
    • Markus, M.A.1    Morris, B.J.2
  • 59
    • 70349265983 scopus 로고    scopus 로고
    • Resveratrol: Cellular actions of a potent natural chemical that confers a diversity of health benefits
    • Marques FZ, Markus MA, Morris BJ. 2009. Resveratrol: Cellular actions of a potent natural chemical that confers a diversity of health benefits. Int J Biochem Cell Biol 41: 2125-2128.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 2125-2128
    • Marques, F.Z.1    Markus, M.A.2    Morris, B.J.3
  • 60
    • 0033952265 scopus 로고    scopus 로고
    • Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production
    • DOI 10.1016/S0006-2952(99)00380-9, PII S0006295299003809
    • Martinez J, Moreno J. 2000. Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production. Biochem Pharmacol 59: 865-870. (Pubitemid 30081710)
    • (2000) Biochemical Pharmacology , vol.59 , Issue.7 , pp. 865-870
    • Martinez, J.1    Moreno, J.J.2
  • 61
    • 0034625386 scopus 로고    scopus 로고
    • Class A scavenger receptor up-regulation in smooth muscle cells by oxidized low density lipoprotein. Enhancement by calcium flux and concurrent cyclooxygenase-2 up-regulation
    • DOI 10.1074/jbc.275.23.17661
    • Mietus-Snyder M, Gowri MS, Pitas RE. 2000. Class A scavenger receptor upregulation in smooth muscle cells by oxidized low density lipoprotein. Enhancement by calcium flux and concurrent cyclooxygenase-2 up-regulation. J Biol Chem 275: 17661-17670. (Pubitemid 30430814)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.23 , pp. 17661-17670
    • Mietus-Snyder, M.1    Gowri, M.S.2    Pitas, R.E.3
  • 63
    • 0029867396 scopus 로고    scopus 로고
    • Wines and grape juices as modulators of platelet aggregation in healthy human subjects
    • DOI 10.1016/0009-8981(96)06236-5
    • Pace-Asciak CR, Rounova O, Hahn SE, et al. 1996. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 246: 163-182. (Pubitemid 26094547)
    • (1996) Clinica Chimica Acta , vol.246 , Issue.1-2 , pp. 163-182
    • Pace-Asciak, C.R.1    Rounova, O.2    Hahn, S.E.3    Diamandis, E.P.4    Goldberg, D.M.5
  • 64
    • 62549115284 scopus 로고    scopus 로고
    • Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats
    • Palsamy P, Subramanian S. 2009. Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats. Chem Biol Interact 179: 356-362.
    • (2009) Chem Biol Interact , vol.179 , pp. 356-362
    • Palsamy, P.1    Subramanian, S.2
  • 65
    • 77953644361 scopus 로고    scopus 로고
    • Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats
    • Palsamy P, Subramanian S. 2010. Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats. J Cell Physiol 224: 423-432.
    • (2010) J Cell Physiol , vol.224 , pp. 423-432
    • Palsamy, P.1    Subramanian, S.2
  • 66
    • 77956591357 scopus 로고    scopus 로고
    • Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells
    • Papoutsis AJ, Lamore SD, Wondrak GT, et al. 2010. Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells. J Nutr 140: 1607-1614.
    • (2010) J Nutr , vol.140 , pp. 1607-1614
    • Papoutsis, A.J.1    Lamore, S.D.2    Wondrak, G.T.3
  • 67
    • 57149123016 scopus 로고    scopus 로고
    • Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium
    • Penumathsa SV, Thirunavukkarasu M, Zhan L, et al. 2008. Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium. J Cell Mol Med 12: 2350-2361.
    • (2008) J Cell Mol Med , vol.12 , pp. 2350-2361
    • Penumathsa, S.V.1    Thirunavukkarasu, M.2    Zhan, L.3
  • 68
    • 0242695672 scopus 로고    scopus 로고
    • Resveratrol: From grapevines to mammalian biology
    • DOI 10.1096/fj.03-0168rev
    • Pervaiz S. 2003. Resveratrol: From grapevines to mammalian biology. FASEB J 17: 1975-1985. (Pubitemid 37392442)
    • (2003) FASEB Journal , vol.17 , Issue.14 , pp. 1975-1985
    • Pervaiz, S.1
  • 69
    • 76249124608 scopus 로고    scopus 로고
    • Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK- mediated p62/SQSTM1 expression and AMPK activation
    • Puissant A, Robert G, Fenouille N, et al. 2010. Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK- mediated p62/SQSTM1 expression and AMPK activation. Cancer Res 70: 1042-1052.
    • (2010) Cancer Res , vol.70 , pp. 1042-1052
    • Puissant, A.1    Robert, G.2    Fenouille, N.3
  • 70
    • 0026651085 scopus 로고
    • Wine, alcohol, platelets, and the French paradox for coronary heart disease
    • Renaud S, de Lorgeril M. 1992. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 339: 1523-1526.
    • (1992) Lancet , vol.339 , pp. 1523-1526
    • Renaud, S.1    De Lorgeril, M.2
  • 71
    • 0036249863 scopus 로고    scopus 로고
    • Interactions of nitric oxide and peroxynitrite with low-density lipoprotein
    • DOI 10.1515/BC.2002.055
    • Rubbo H, Trostchansky A, Botti H, et al. 2002. Interactions of nitric oxide and peroxynitrite with low-density lipoprotein. Biol Chem 383: 547-552. (Pubitemid 34506290)
    • (2002) Biological Chemistry , vol.383 , Issue.3-4 , pp. 547-552
    • Rubbo, H.1    Trostchansky, A.2    Botti, H.3    Batthyany, C.4
  • 73
    • 38649132291 scopus 로고    scopus 로고
    • Resveratrol and its analogs: Defense against cancer, coronary disease and neurodegenerative maladies or just a fad?
    • DOI 10.1016/j.mrrev.2007.08.004, PII S1383574207000324
    • Saiko P, Szakmary A, Jaeger W, et al. 2008. Resveratrol and its analogs: Defense against cancer, coronary disease and neurodegenerative maladies or just a fad? Mutat Res 658: 68-94. (Pubitemid 351172881)
    • (2008) Mutation Research - Reviews in Mutation Research , vol.658 , Issue.1-2 , pp. 68-94
    • Saiko, P.1    Szakmary, A.2    Jaeger, W.3    Szekeres, T.4
  • 74
    • 65049090141 scopus 로고    scopus 로고
    • Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin- induced diabetic rats
    • Schmatz R, Mazzanti CM, Spanevello R, et al. 2009. Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin- induced diabetic rats. Eur J Pharmacol 610: 42-48.
    • (2009) Eur J Pharmacol , vol.610 , pp. 42-48
    • Schmatz, R.1    Mazzanti, C.M.2    Spanevello, R.3
  • 76
    • 77649189281 scopus 로고    scopus 로고
    • Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells
    • Shu XH, Li H, Sun Z, et al. 2010. Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells. Biochem Pharmacol 79: 1516-1525.
    • (2010) Biochem Pharmacol , vol.79 , pp. 1516-1525
    • Shu, X.H.1    Li, H.2    Sun, Z.3
  • 77
    • 27244461732 scopus 로고    scopus 로고
    • Efficiency and mechanism of the antioxidant action of trans-resveratrol and its analogues in the radical liposome oxidation
    • DOI 10.1006/abbi.2001.2388
    • Stojanovic S, Sprinz H, Brede O. 2001. Efficiency and mechanism of the antioxidant action of trans-resveratrol and its analogues in the radical liposome oxidation. Arch Biochem Biophys 391: 79-89. (Pubitemid 32612575)
    • (2001) Archives of Biochemistry and Biophysics , vol.391 , Issue.1 , pp. 79-89
    • Stojanovic, S.1    Sprinz, H.2    Brede, O.3
  • 79
    • 77749254621 scopus 로고    scopus 로고
    • Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy
    • Sulaiman M, Matta MJ, Sunderesan NR, et al. 2010. Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol 298: H833-H843.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Sulaiman, M.1    Matta, M.J.2    Sunderesan, N.R.3
  • 80
    • 84868537428 scopus 로고    scopus 로고
    • Mitochondrial nutrients stimulate performance and mitochondrial biogenesis in exhaustively exercised rats
    • DOI: 10.1111/j.1600-0838.2011. 01314.x
    • Sun M, Qian F, Shen W, Tian C, Hao J, Sun L, Liu J. 2011. Mitochondrial nutrients stimulate performance and mitochondrial biogenesis in exhaustively exercised rats. Scand J Med Sci Sports DOI: 10.1111/j.1600-0838.2011. 01314.x.
    • (2011) Scand J Med Sci Sports
    • Sun, M.1    Qian, F.2    Shen, W.3    Tian, C.4    Hao, J.5    Sun, L.6    Liu, J.7
  • 81
    • 77955271629 scopus 로고    scopus 로고
    • Beta-arrestin 2 modulates resveratrolinduced apoptosis and regulation of Akt/GSK3ß pathways
    • Sun X, Zhang Y, Wang J, et al. 2010. Beta-arrestin 2 modulates resveratrolinduced apoptosis and regulation of Akt/GSK3ß pathways. Biochim Biophys Acta 1800: 912-918.
    • (2010) Biochim Biophys Acta , vol.1800 , pp. 912-918
    • Sun, X.1    Zhang, Y.2    Wang, J.3
  • 82
    • 34250221512 scopus 로고    scopus 로고
    • S) mice: Activation of SIRT2, an NAD-dependent tubulin deacetylase
    • DOI 10.1016/j.bbrc.2007.05.164, PII S0006291X07011394
    • Suzuki K, Koike T. 2007. Resveratrol abolishes resistance to axonal degeneration in slow Wallerian degeneration (WldS) mice: Activation of SIRT2, an NAD-dependent tubulin deacetylase. Biochem Biophys Res Commun 359: 665-671. (Pubitemid 46899003)
    • (2007) Biochemical and Biophysical Research Communications , vol.359 , Issue.3 , pp. 665-671
    • Suzuki, K.1    Koike, T.2
  • 83
    • 48849086013 scopus 로고    scopus 로고
    • Change in histone H3 phosphorylation, MAP kinase p38, SIR 2 and p53 expression by resveratrol in preventing streptozotocin induced type i diabetic nephropathy
    • Tikoo K, Singh K, Kabra D, et al. 2008. Change in histone H3 phosphorylation, MAP kinase p38, SIR 2 and p53 expression by resveratrol in preventing streptozotocin induced type I diabetic nephropathy. Free Radic Res 42: 397-404.
    • (2008) Free Radic Res , vol.42 , pp. 397-404
    • Tikoo, K.1    Singh, K.2    Kabra, D.3
  • 84
    • 77956290858 scopus 로고    scopus 로고
    • Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD
    • Tili E, Michaille JJ, Adair B, et al. 2010. Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD. Carcinogenesis 31: 1561-1566.
    • (2010) Carcinogenesis , vol.31 , pp. 1561-1566
    • Tili, E.1    Michaille, J.J.2    Adair, B.3
  • 85
    • 0033023541 scopus 로고    scopus 로고
    • Suppression of nitric oxide synthase and the down-regulation of the activation of NF-κB in macrophages by resveratrol
    • Tsai SH, Lin-Shiau SY, Lin JK. 1999. Suppression of nitric oxide synthase and the down-regulation of the activation of NF-κB in macrophages by resveratrol. Br J Pharmacol 126: 673-680.
    • (1999) Br J Pharmacol , vol.126 , pp. 673-680
    • Tsai, S.H.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 86
    • 77953741269 scopus 로고    scopus 로고
    • Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2
    • Ungvari Z, Bagi Z, Feher A, et al. 2010. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol 299: H18-H24.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Ungvari, Z.1    Bagi, Z.2    Feher, A.3
  • 87
    • 70350464512 scopus 로고    scopus 로고
    • Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells
    • Ungvari Z, Labinskyy N, Mukhopadhyay P, et al. 2009. Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells. Am J Physiol Heart Circ Physiol 297: H1876-H1881.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Ungvari, Z.1    Labinskyy, N.2    Mukhopadhyay, P.3
  • 88
    • 77952611330 scopus 로고    scopus 로고
    • Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways
    • Vanamala J, Reddivari L, Radhakrishnan S, et al. 2010. Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways. BMC Cancer 10: 238.
    • (2010) BMC Cancer , vol.10 , pp. 238
    • Vanamala, J.1    Reddivari, L.2    Radhakrishnan, S.3
  • 90
    • 34249103889 scopus 로고    scopus 로고
    • Resveratrol inhibits proliferation of cultured rat cardiac fibroblasts: Correlated with NO-cGMP signaling pathway
    • DOI 10.1016/j.ejphar.2007.04.023, PII S0014299907004803
    • Wang S, Wang X, Yan J, et al. 2007. Resveratrol inhibits proliferation of cultured rat cardiac fibroblasts: Correlated with NO-cGMP signaling pathway. Eur J Pharmacol 567: 26-35. (Pubitemid 46795491)
    • (2007) European Journal of Pharmacology , vol.567 , Issue.1-2 , pp. 26-35
    • Wang, S.1    Wang, X.2    Yan, J.3    Xie, X.4    Fan, F.5    Zhou, X.6    Han, L.7    Chen, J.8
  • 91
    • 77649305163 scopus 로고    scopus 로고
    • Differential effects of resveratrol and its naturally occurring methylether analogs on cell cycle and apoptosis in human androgen- responsive LNCaP cancer cells
    • Wang TT, Schoene NW, Kim YS, et al. 2010. Differential effects of resveratrol and its naturally occurring methylether analogs on cell cycle and apoptosis in human androgen- responsive LNCaP cancer cells. Mol Nutr Food Res 54: 335-344.
    • (2010) Mol Nutr Food Res , vol.54 , pp. 335-344
    • Wang, T.T.1    Schoene, N.W.2    Kim, Y.S.3
  • 92
    • 77949367262 scopus 로고    scopus 로고
    • Evaluation of anti-invasion effect of resveratrol and related methoxy analogues on human hepatocarcinoma cells
    • Weng CJ, Wu CF, Huang HW, et al. 2010. Evaluation of anti-invasion effect of resveratrol and related methoxy analogues on human hepatocarcinoma cells. J Agric Food Chem 58: 2886-2894.
    • (2010) J Agric Food Chem , vol.58 , pp. 2886-2894
    • Weng, C.J.1    Wu, C.F.2    Huang, H.W.3
  • 93
    • 34250330808 scopus 로고    scopus 로고
    • Low concentrations of resveratrol potentiate the antiplatelet effect of prostaglandins
    • Wu CC, Wu CI, Wang WY, et al. 2007. Low concentrations of resveratrol potentiate the antiplatelet effect of prostaglandins. Planta Med 73: 439-443.
    • (2007) Planta Med , vol.73 , pp. 439-443
    • Wu, C.C.1    Wu, C.I.2    Wang, W.Y.3
  • 94
    • 39649090942 scopus 로고    scopus 로고
    • Resveratrol attenuates thromboxane A2 receptor agonist-induced platelet activation by reducing phospholipase C activity
    • Yang YM, Chen JZ, Wang XX, et al. 2008a. Resveratrol attenuates thromboxane A2 receptor agonist-induced platelet activation by reducing phospholipase C activity. Eur J Pharmacol 583: 148-155.
    • (2008) Eur J Pharmacol , vol.583 , pp. 148-155
    • Yang, Y.M.1    Chen, J.Z.2    Wang, X.X.3
  • 95
    • 44949236212 scopus 로고    scopus 로고
    • Resveratrol attenuates adenosine diphosphate-induced platelet activation by reducing protein kinase C activity
    • Yang YM, Wang XX, Chen JZ, et al. 2008b. Resveratrol attenuates adenosine diphosphate-induced platelet activation by reducing protein kinase C activity. Am J Chin Med 36: 603-613.
    • (2008) Am J Chin Med , vol.36 , pp. 603-613
    • Yang, Y.M.1    Wang, X.X.2    Chen, J.Z.3
  • 96
    • 67650070375 scopus 로고    scopus 로고
    • 2-induced apoptosis and expression of SIRTs in H9c2cells
    • 2-induced apoptosis and expression of SIRTs in H9c2cells.J Cell Biochem 107: 741-747.
    • (2009) Cell Biochem , vol.107 , pp. 741-747
    • Yu, W.1    Fu, Y.C.2    Zhou, X.H.3
  • 97
    • 68149150584 scopus 로고    scopus 로고
    • Resveratrol improves endothelial function: Role of TNF{alpha} and vascular oxidative stress
    • Zhang H, Zhang J, Ungvari Z, et al. 2009. Resveratrol improves endothelial function: Role of TNF{alpha} and vascular oxidative stress. Arterioscler Thromb Vasc Biol 29: 1164-1171.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1164-1171
    • Zhang, H.1    Zhang, J.2    Ungvari, Z.3
  • 98
    • 0033129760 scopus 로고    scopus 로고
    • Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice
    • Zhong M, Cheng GF, Wang WJ, et al. 1999. Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice. Phytomedicine 6: 79-84. (Pubitemid 129634463)
    • (1999) Phytomedicine , vol.6 , Issue.2 , pp. 79-84
    • Zhong, M.1    Cheng, G.F.2    Wang, W.J.3    Guo, Y.4    Zhu, X.Y.5    Zhang, J.T.6
  • 99
    • 0042773944 scopus 로고    scopus 로고
    • Effect of red wine and wine polyphenol resveratrol on endothelial function in hypercholesterolemic rabbits
    • Zou JG, Wang ZR, Huang YZ, et al. 2003. Effect of red wine and wine polyphenol resveratrol on endothelial function in hypercholesterolemic rabbits. Int J Mol Med 11: 317-320.
    • (2003) Int J Mol Med , vol.11 , pp. 317-320
    • Zou, J.G.1    Wang, Z.R.2    Huang, Y.Z.3


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