Resveratrol exhibits cytostatic and antiestrogenic properties with human endometrial adenocarcinoma (Ishikawa) cells

Cancer Research

Volumn 61, Issue 16, 2001, Pages 6137-6144

  Bhat, K P L ^a   Pezzuto, J M ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RESVERATROL;

ADENOCARCINOMA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; CYTOSTASIS; DRUG EFFECT; ENDOMETRIUM CARCINOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ADENOCARCINOMA; ALKALINE PHOSPHATASE; ANTIGENS, CD; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CDC2-CDC28 KINASES; CELL SURVIVAL; CYCLIN A; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; DOWN-REGULATION; DRUG INTERACTIONS; ENDOMETRIAL NEOPLASMS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGEN RECEPTOR MODULATORS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTEGRIN ALPHA1; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; RNA, MESSENGER; S PHASE; STILBENES; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED;

EID: 0035881270     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. The production of resveratrol by Vitis vinifera and other members of the Vitaceae as a response to infection or injury
2. Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the 'French paradox'?
3. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
4. Effects of resveratrol on 12-O-tetradecanoylphorbol-13 -acetate-induced oxidative events and gene expression in mouse skin
5. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorhol ester-treated human mammary epithelial cells
6. Resveratrol is a selective human cytochrome P450 1A1 inhibitor
7. Chemopreventive properties of transresveratrol are associated with inhibition of activation of the IκB kinase
8. Resveratrol inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells
9. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids
10. Resveratrol preferentially inhibits protein kinase C-catalyzed phosphorylation of a cofactor-independent, arginine-rich protein substrate by a novel mechanism
11. Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling dependent apoptosis in human tumor cells
12. Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells
13. Resveratrol: A molecule whose time has come? and gone?
14. Phytoestrogens act as estrogen agonists in an estrogen-responsive pituitary cell line
15. Stimulation of pS2 expression by diet-derived compounds
16. In vitro bioassays of non-steroidal phytoestrogens
17. Soy intake and cancer risk: A review of the in vitro and in vivo data
18. Dietary soybean may be antiestrogenic in male mice
19. Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro
20. Effects of phytoestrogens on aromatase, 3β and 17β-hydroxysteroid dehydrogenase activities and human breast cancer cells
21. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor
22. Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
23. Antiproliferative effect of synthetic resveratrol on human breast epithelial cells
24. Effect of tamoxifen on endometrial proliferation
25. Cell-based assay for the determination of estrogenic and anti-estrogenic activities
26. Use of reverse transcription-polymerase chain reaction methodology to detect estrogen-regulated gene expression in small breast cancer specimens
27. Altered estrogen receptor a and β messenger RNA expression during human breast tumorigenesis
28. Hormone- and DNA-binding mechanisms of the recombinant human estrogen receptor
29. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
30. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β
31. Estrogenic/antiestrogenic and scavenging properties of (E)- and (Z)-resveratrol
32. Endometrial cancer and estrogen use. Report of a large case-control study
33. Estrogen regulation of placental alkaline phosphatase gene expression in a human endometrial adenocarcinoma cell line
34. Blockade of the stimulatory effect of estrogens, OH-tamoxifen, OH- toremifene, droloxifene, and raloxifene on alkaline phosphatase activity by the antiestrogen EM-800 in human endometrial adenocarcinoma Ishikawa cells
35. Estrogen response elements can mediate agonist activity of anti-estrogens in human endometrial Ishikawa cells
36. Characterization of the functional progesterone receptor in an endometrial adenocarcinoma cell line (Ishikawa): Progesterone-induced expression of the α1 integrin
37. Epithelial integrins
38. Partial and weak oestrogenecity of the red wine constituent resveratrol: Consideration of its superagonist activity in MCF-7 cells and its suggested cardiovascular protective effects
39. Ligand structure-dependent differences in activation of estrogen receptor α in human HepG2 liver and U2 osteogenic cancer cell lines
40. Resveratrol acts as a mixed agonist/antagonist for estrogen receptors α and β
41. Differential response of immature rat uterine tissue to ethinylestradiol and the red wine constituent resveratrol
42. Eukaryotic DNA topoisomerase I: Genome gate keeper and its intruders, camptothecins
43. Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function
44. Interferon-β induces S phase slowing via up-regulated expression of PML in squamous carcinoma cells
45. Normal G1/S transition and prolonged S phase within one cell cycle after seeding cells in the presence of an ornithine decarboxylase inhibitor
46. Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells
47. Resveratrol, a remarkable inhibitor of ribonucleotide reductase
48. DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia
49. Resveratrol arrests the cell division cycle at S/G2 phase transition
50. 2
51. Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials
52. Chemopreventive agent resveratrol, a natural product derived from grapes, reversibly inhibits progression through S and G2 phases of the cell cycle in U937 cells