메뉴 건너뛰기




Volumn 898, Issue , 2012, Pages 1-40

Essential role of genetics in the advancement of biotechnology

Author keywords

Agriculture; Bioconversions; Biopharmaceuticals; Enzymes; Genetic engineering; Hosts; Metabolic engineering; Polymers; Primary metabolites; Secondary metabolites

Indexed keywords

DRUG; RECOMBINANT PROTEIN;

EID: 84864148372     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-918-1_1     Document Type: Article
Times cited : (4)

References (261)
  • 1
    • 0036161274 scopus 로고    scopus 로고
    • A novel methodology employing corynebacterium glutamicum genome information to generate a new L-lysine-producing mutant
    • Ohnishi J, Mitsuhashi S, Hayashi M, Ando S, Yokoi H, Ochiai K et al (2002) A novel methodology employing Corynebacterium glutamicum genome information to generate a new L-lysine-producing mutant. Appl Microbiol Biotechnol 58:217-223
    • (2002) Appl. Microbiol. Biotechnol. , vol.58 , pp. 217-223
    • Ohnishi, J.1    Mitsuhashi, S.2    Hayashi, M.3    Ando, S.4    Yokoi, H.5    Ochiai, K.6
  • 2
    • 0032600888 scopus 로고    scopus 로고
    • Metabolic fluxes and metabolic engineering
    • Stephanopoulos G (1999) Metabolic fl uxes and metabolic engineering. Metab Eng 1:1-11
    • (1999) Metab. Eng. , vol.1 , pp. 1-11
    • Stephanopoulos, G.1
  • 4
    • 0033782932 scopus 로고    scopus 로고
    • Pathway analysis and metabolic engineering in Corynebacterium glutamicum
    • Sahm H, Eggeling L, De Graaf AA (2000) Pathway analysis and metabolic engineering in Corynebacterium glutamicum . Biol Chem 381:899-910
    • (2000) Biol. Chem. , vol.381 , pp. 899-910
    • Sahm, H.1    Eggeling, L.2    De Graaf, A.A.3
  • 5
    • 43049136820 scopus 로고    scopus 로고
    • Combinatorial engineering of microbes for optimizing cellular phenotype
    • Santos CSS, Stephanopoulos G (2008) Combinatorial engineering of microbes for optimizing cellular phenotype. Curr Opin Chem Biol 12:168-176
    • (2008) Curr. Opin. Chem. Biol. , vol.12 , pp. 168-176
    • Santos, C.S.S.1    Stephanopoulos, G.2
  • 8
    • 0030754926 scopus 로고    scopus 로고
    • Optimization of DNA shuf fl ing for high fi delity recombination
    • Zhao H, Arnold FH (1997) Optimization of DNA shuf fl ing for high fi delity recombination. Nucleic Acids Res 25:1307-1308
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1307-1308
    • Zhao, H.1    Arnold, F.H.2
  • 9
  • 11
    • 65049084532 scopus 로고    scopus 로고
    • Novel methods of genome shuf fling in Saccharomyces cerevisiae
    • Hou L (2009) Novel methods of genome shuf fl ing in Saccharomyces cerevisiae . Biotechnol Lett 31:671-677
    • (2009) Biotechnol. Lett. , vol.31 , pp. 671-677
    • Hou, L.1
  • 12
    • 5044237367 scopus 로고    scopus 로고
    • Exploiting biological complexity for strain improvement through systems biology
    • Stephanopoulos G, Alper H, Moxley J (2004) Exploiting biological complexity for strain improvement through systems biology. Nat Biotechnol 22:1261-1267
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1261-1267
    • Stephanopoulos, G.1    Alper, H.2    Moxley, J.3
  • 13
    • 28344455644 scopus 로고    scopus 로고
    • Biotechnological production of amino acids and derivatives: Current status and prospects
    • Leuchtenberger W, Huthmacher K, Drauz K (2005) Biotechnological production of amino acids and derivatives: Current status and prospects. Appl Microbiol Biotechnol 69:1-8
    • (2005) Appl. Microbiol. Biotechnol. , vol.69 , pp. 1-8
    • Leuchtenberger, W.1    Huthmacher, K.2    Drauz, K.3
  • 14
    • 38049185013 scopus 로고    scopus 로고
    • Microbial production of L-glutamate and L-glutamine by recombinant Corynebacterium glutamicum harboring Vitreoscilla hemoglobin gene vgb
    • Liu Q, Zhang J, Wei X-X, Ouyang S-P, Wu Q, Chen G-Q (2008) Microbial production of L-glutamate and L-glutamine by recombinant Corynebacterium glutamicum harboring Vitreoscilla hemoglobin gene vgb . Appl Microbiol Biotechnol 77:1297-1304
    • (2008) Appl. Microbiol. Biotechnol. , vol.77 , pp. 1297-1304
    • Liu, Q.1    Zhang, J.2    Wei, X.-X.3    Ouyang, S.-P.4    Wu, Q.5    Chen, G.-Q.6
  • 15
    • 34047252012 scopus 로고    scopus 로고
    • Innovative metabolic pathway design for Efficient L-glutamate production by suppreassing CO 2 emission
    • Chinen A, Kozlov YI, Hara Y, Izui H, Yasueda H (2007) Innovative metabolic pathway design for Efficient L-glutamate production by suppreassing CO 2 emission. J Biosci Bioeng 103:262-269
    • (2007) J. Biosci. Bioeng. , vol.103 , pp. 262-269
    • Chinen, A.1    Kozlov, Y.I.2    Hara, Y.3    Izui, H.4    Yasueda, H.5
  • 16
    • 11144261828 scopus 로고    scopus 로고
    • A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum
    • Ohnishi J, Katahira R, Mitsuhashi S, Kakita S, Ikeda M (2005) A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum . FEMS Microbiol Lett 242:265-274
    • (2005) FEMS Microbiol. Lett. , vol.242 , pp. 265-274
    • Ohnishi, J.1    Katahira, R.2    Mitsuhashi, S.3    Kakita, S.4    Ikeda, M.5
  • 17
    • 33745013345 scopus 로고    scopus 로고
    • A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for Efficient L-lysine production
    • Ikeda M, Ohnishi J, Hayashi M, Mitsuhashi S (2006) A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for Efficient L-lysine production. J Ind Microbiol Biotechnol 33:610-615
    • (2006) J. Ind. Microbiol. Biotechnol. , vol.33 , pp. 610-615
    • Ikeda, M.1    Ohnishi, J.2    Hayashi, M.3    Mitsuhashi, S.4
  • 18
    • 33344461468 scopus 로고    scopus 로고
    • Transcriptome analysis reveals global expression changes in an industrial L-lysine producer of Corynebacterium glutamicum
    • Hiyashi M, Ohnishi J, Mitsuhashi S, Yonetani Y, Hashimoto S, Ikeda M (2006) Transcriptome analysis reveals global expression changes in an industrial L-lysine producer of Corynebacterium glutamicum . Biosci Biotechnol Biochem 70:546-550
    • (2006) Biosci. Biotechnol. Biochem. , vol.70 , pp. 546-550
    • Hiyashi, M.1    Ohnishi, J.2    Mitsuhashi, S.3    Yonetani, Y.4    Hashimoto, S.5    Ikeda, M.6
  • 19
    • 34548050175 scopus 로고    scopus 로고
    • The three tricarboxylate synthase activities of Corynebacterium glutamicum and increase of L-lysine synthesis
    • Radmacher E, Eggeling L (2007) The three tricarboxylate synthase activities of Corynebacterium glutamicum and increase of L-lysine synthesis. Appl Microbiol Biotechnol 76:587-595
    • (2007) Appl. Microbiol. Biotechnol. , vol.76 , pp. 587-595
    • Radmacher, E.1    Eggeling, L.2
  • 20
    • 34548021634 scopus 로고    scopus 로고
    • Effect of pyruvate dehydrogenase complex Deficiency on L-lysine production with Corynebacterium glutamicum
    • Blombach B, Schreiner ME, Moch M, Oldiges M, Eikmanns BJ (2007) Effect of pyruvate dehydrogenase complex Deficiency on L-lysine production with Corynebacterium glutamicum . Appl Microbiol Biotechnol 76: 615-623
    • (2007) Appl. Microbiol. Biotechnol. , vol.76 , pp. 615-623
    • Blombach, B.1    Schreiner, M.E.2    Moch, M.3    Oldiges, M.4    Eikmanns, B.J.5
  • 21
    • 34548043216 scopus 로고    scopus 로고
    • Improving lysine production by Corynebacterium glutamicum through DNA microarray-based Identification of novel target genes
    • Sindelar G, Wendisch VF (2007) Improving lysine production by Corynebacterium glutamicum through DNA microarray-based Identification of novel target genes. Appl Microbiol Biotechnol 76:677-689
    • (2007) Appl. Microbiol. Biotechnol. , vol.76 , pp. 677-689
    • Sindelar, G.1    Wendisch, V.F.2
  • 22
    • 0018579738 scopus 로고
    • Transductional construction of a threonineproducing strain of Serratia marcescens
    • Komatsubara S, Kisumi M, Chibata I (1979) Transductional construction of a threonineproducing strain of Serratia marcescens . Appl Environ Microbiol 38:1045-1051
    • (1979) Appl. Environ. Microbiol. , vol.38 , pp. 1045-1051
    • Komatsubara, S.1    Kisumi, M.2    Chibata, I.3
  • 23
    • 0020619548 scopus 로고
    • Transductional construction of a threoninehyperproducing strain of Serratia marcescens: Lack of feedback controls of three aspartokinases and two homoserine dehydrogenases
    • Komatsubara S, Kisumi M, Chibata I (1983) Transductional construction of a threoninehyperproducing strain of Serratia marcescens: Lack of feedback controls of three aspartokinases and two homoserine dehydrogenases. Appl Environ Microbiol 45:1445-1452
    • (1983) Appl. Environ. Microbiol. , vol.45 , pp. 1445-1452
    • Komatsubara, S.1    Kisumi, M.2    Chibata, I.3
  • 24
    • 0043205398 scopus 로고
    • Construction of a threonine-hyperproducing strain of Serratia marcescens by amplifying the phosphoenolpyruvate carboxylase gene
    • Sugita T, Komatsubara S (1989) Construction of a threonine-hyperproducing strain of Serratia marcescens by amplifying the phosphoenolpyruvate carboxylase gene. Appl Microbiol Biotechnol 30:290-293
    • (1989) Appl. Microbiol. Biotechnol. , vol.30 , pp. 290-293
    • Sugita, T.1    Komatsubara, S.2
  • 26
    • 85007989254 scopus 로고
    • Factors improving L-threonine production by a three L-threonine biosynthetic genes-ampli fi ed recombinant strain of Brevibacterium lactofermentum
    • Ishida M, Kawashima H, Sato K, Hashiguchi K, Ito H, Enei H et al (1994) Factors improving L-threonine production by a three L-threonine biosynthetic genes-ampli fi ed recombinant strain of Brevibacterium lactofermentum . Biosci Biotechnol Biochem 58:768-770
    • (1994) Biosci. Biotechnol. Biochem. , vol.58 , pp. 768-770
    • Ishida, M.1    Kawashima, H.2    Sato, K.3    Hashiguchi, K.4    Ito, H.5    Enei, H.6
  • 27
    • 0001474927 scopus 로고    scopus 로고
    • Amino acid production: Principles of metabolic engineering
    • Lee SY, Papoutsakis ET (eds Marcel Dekker, New York
    • Eggeling L, Sahm H (1999) Amino acid production: Principles of metabolic engineering. In: Lee SY, Papoutsakis ET (eds) Metabolic engineering. Marcel Dekker, New York, pp 153-176
    • (1999) Metabolic Engineering , pp. 153-176
    • Eggeling, L.1    Sahm, H.2
  • 29
    • 36849002434 scopus 로고    scopus 로고
    • Systems metabolic engineering of Escherichia coli for L-threonine production
    • Lee KH, Park JH, Kim TY, Kim HU, Lee SY (2007) Systems metabolic engineering of Escherichia coli for L-threonine production. Mol Syst Biol 3:149-157
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 149-157
    • Lee, K.H.1    Park, J.H.2    Kim, T.Y.3    Kim, H.U.4    Lee, S.Y.5
  • 30
    • 34249934691 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout stimulation
    • Park JH, Lee KH, Kim TY, Lee SY (2007) Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout stimulation. Proc Natl Acad Sci USA 104:7797-7802
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 7797-7802
    • Park, J.H.1    Lee, K.H.2    Kim, T.Y.3    Lee, S.Y.4
  • 31
    • 0037883611 scopus 로고    scopus 로고
    • Global expression profiling and physiological characterization of Corynebacterium glutamicum grown in the presence of L-valine
    • Lange C, Rittmann D, Wendisch VF, Bott M, Sahm H (2003) Global expression profiling and physiological characterization of Corynebacterium glutamicum grown in the presence of L-valine. Appl Environ Microbiol 69:2521-2532
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 2521-2532
    • Lange, C.1    Rittmann, D.2    Wendisch, V.F.3    Bott, M.4    Sahm, H.5
  • 32
    • 0017670058 scopus 로고
    • Enhancement of isoleucine hydroxamatemediated growth inhibition and improvement of isoleucine-producing strains of Serratia marcescens
    • Kisumi M, Komatsubara S, Chibata I (1977) Enhancement of isoleucine hydroxamatemediated growth inhibition and improvement of isoleucine-producing strains of Serratia marcescens . Appl Environ Microbiol 34: 647-653
    • (1977) Appl. Environ. Microbiol. , vol.34 , pp. 647-653
    • Kisumi, M.1    Komatsubara, S.2    Chibata, I.3
  • 33
    • 0033014686 scopus 로고    scopus 로고
    • Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production
    • Guillouet S, Rodal AA, An G-H, Lessard PA, Sinskey AJ (1999) Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl Environ Microbiol 65:3100-3107
    • (1999) Appl. Environ. Microbiol. , vol.65 , pp. 3100-3107
    • Guillouet, S.1    Rodal, A.A.2    An, G.-H.3    Lessard, P.A.4    Sinskey, A.J.5
  • 34
    • 0029860181 scopus 로고    scopus 로고
    • L-Isoleucine production with Corynebacterium glutamicum: Further fl ux increase and limitation of export
    • Morbach S, Sahm H, Eggeling L (1996) L-Isoleucine production with Corynebacterium glutamicum: Further fl ux increase and limitation of export. Appl Environ Microbiol 62: 4345-4351
    • (1996) Appl. Environ. Microbiol. , vol.62 , pp. 4345-4351
    • Morbach, S.1    Sahm, H.2    Eggeling, L.3
  • 36
    • 0343581287 scopus 로고
    • The fruits of molecular physiology: Engineering the L-isoleucine biosynthesis pathway in Corynebacterium glutamicum
    • Eggeling L, Morbach S, Sahm H (1977) The fruits of molecular physiology: Engineering the L-isoleucine biosynthesis pathway in Corynebacterium glutamicum . J Biotechnol 56:167-182
    • (1977) J. Biotechnol. , vol.56 , pp. 167-182
    • Eggeling, L.1    Morbach, S.2    Sahm, H.3
  • 38
    • 0011727274 scopus 로고
    • L-Isoleucine production by analog-resistant mutants derived from threonine-producing strain of Corynebacterium glutamicum
    • Kase H, Nakayama K (1977) L-Isoleucine production by analog-resistant mutants derived from threonine-producing strain of Corynebacterium glutamicum . Agric Biol Chem 41:109-116
    • (1977) Agric. Biol. Chem. , vol.41 , pp. 109-116
    • Kase, H.1    Nakayama, K.2
  • 39
    • 0028791418 scopus 로고
    • Use of feedback-resistant threonine dehydratases of Corynebacterium glutamicum to increase carbon fl ux towards L-isoleucine
    • Morbach S, Sahm H, Eggeling L (1995) Use of feedback-resistant threonine dehydratases of Corynebacterium glutamicum to increase carbon fl ux towards L-isoleucine. Appl Environ Microbiol 61:4315-4320
    • (1995) Appl. Environ. Microbiol. , vol.61 , pp. 4315-4320
    • Morbach, S.1    Sahm, H.2    Eggeling, L.3
  • 40
    • 0029884122 scopus 로고    scopus 로고
    • Engineering the homoserine dehydrogenase and threonine dehydratase control points to analyse fl ux towards L-isoleucine in Corynebacterium glutamicum
    • Morbach S, Kelle R, Winkels S, Sahm H, Eggeling L (1996) Engineering the homoserine dehydrogenase and threonine dehydratase control points to analyse fl ux towards L-isoleucine in Corynebacterium glutamicum . Appl Microbiol Biotechnol 45:612-620
    • (1996) Appl. Microbiol. Biotechnol. , vol.45 , pp. 612-620
    • Morbach, S.1    Kelle, R.2    Winkels, S.3    Sahm, H.4    Eggeling, L.5
  • 41
    • 0032998388 scopus 로고    scopus 로고
    • Construction of L-isoleucineoverproducing strains of Corynebacterium glutamicum
    • Sahm H, Eggeling L, Morbach S, Eikmanns B (1999) Construction of L-isoleucineoverproducing strains of Corynebacterium glutamicum . Naturwissenschaften 86:33-38
    • (1999) Naturwissenschaften , vol.86 , pp. 33-38
    • Sahm, H.1    Eggeling, L.2    Morbach, S.3    Eikmanns, B.4
  • 42
    • 0015890810 scopus 로고
    • Production of L-isoleucine by AHV resistant mutants of Brevibacterium fl avum
    • Shiio I, Sasaki A, Nakamori S, Sano K (1973) Production of L-isoleucine by AHV resistant mutants of Brevibacterium fl avum . Agric Biol Chem 37:2053-2061
    • (1973) Agric. Biol. Chem. , vol.37 , pp. 2053-2061
    • Shiio, I.1    Sasaki, A.2    Nakamori, S.3    Sano, K.4
  • 43
    • 0017158836 scopus 로고
    • Culture conditions of L-isoleucine fermentation from acetic acid
    • Ikeda S, Fujita I, Hirose Y (1976) Culture conditions of L-isoleucine fermentation from acetic acid. Agric Biol Chem 40:517-522
    • (1976) Agric. Biol. Chem. , vol.40 , pp. 517-522
    • Ikeda, S.1    Fujita, I.2    Hirose, Y.3
  • 44
    • 3843134039 scopus 로고    scopus 로고
    • Aerobic production of alanine by Escherichia coli aceF IdhA mutants expressing the Bacillus sphaericus alaD gene
    • Lee M, Smith GM, Eiteman MA, Altman E (2004) Aerobic production of alanine by Escherichia coli aceF IdhA mutants expressing the Bacillus sphaericus alaD gene. Appl Microbiol Biotechnol 65:56-60
    • (2004) Appl. Microbiol. Biotechnol. , vol.65 , pp. 56-60
    • Lee, M.1    Smith, G.M.2    Eiteman, M.A.3    Altman, E.4
  • 45
    • 77953553412 scopus 로고
    • The use of genetically engineered strains of Escherichia coli for the overproduction of free amino acids: Proline as a model system
    • Downey K, Voellmy RW (eds Academic, New York
    • Bloom F, Smith CJ, Jessee J, Veileux B, Deutch AH (1984) The use of genetically engineered strains of Escherichia coli for the overproduction of free amino acids: Proline as a model system. In: Downey K, Voellmy RW (eds) Advances in gene technology: Molecular genetics of plants and animals. Academic, New York, pp 383-394
    • (1984) Advances in Gene Technology: Molecular Genetics of Plants and Animals , pp. 383-394
    • Bloom, F.1    Smith, C.J.2    Jessee, J.3    Veileux, B.4    Deutch, A.H.5
  • 46
    • 0021949984 scopus 로고
    • Proline production by regulatory mutants of Serratia marcescens
    • Sugiura M, Takagi T, Kisumu M (1995) Proline production by regulatory mutants of Serratia marcescens . Appl Microbiol Biotechnol 21:213-239
    • (1995) Appl. Microbiol. Biotechnol. , vol.21 , pp. 213-239
    • Sugiura, M.1    Takagi, T.2    Kisumu, M.3
  • 47
    • 0022377661 scopus 로고
    • Improvement of a proline-producing strain of Serratia marcescens by subcloning of a mutant allele of the proline gene
    • Sugiura M, Imai Y, Takagi T, Kisumi M (1985) Improvement of a proline-producing strain of Serratia marcescens by subcloning of a mutant allele of the proline gene. J Biotechnol 3:47-58
    • (1985) J. Biotechnol. , vol.3 , pp. 47-58
    • Sugiura, M.1    Imai, Y.2    Takagi, T.3    Kisumi, M.4
  • 48
    • 0027768557 scopus 로고
    • Improvement of culture conditions for L-proline production by a recombinant strain of Serratia marcescens
    • Masuda M, Takamatu S, Nishimura N, Komatsubara S, Tosa T (1993) Improvement of culture conditions for L-proline production by a recombinant strain of Serratia marcescens . Appl Biochem Biotechnol 43:189-197
    • (1993) Appl. Biochem. Biotechnol. , vol.43 , pp. 189-197
    • Masuda, M.1    Takamatu, S.2    Nishimura, N.3    Komatsubara, S.4    Tosa, T.5
  • 49
    • 0542431613 scopus 로고
    • Improvement of L-proline production by sulfaguanidine resistant mutants derived from L-glutamic acid-producing bacteria
    • Tsuchida T, Kubota K, Yoshinaga F (1986) Improvement of L-proline production by sulfaguanidine resistant mutants derived from L-glutamic acid-producing bacteria. Agric Biol Chem 50:2201-2207
    • (1986) Agric. Biol. Chem. , vol.50 , pp. 2201-2207
    • Tsuchida, T.1    Kubota, K.2    Yoshinaga, F.3
  • 50
    • 77953586608 scopus 로고
    • Conversion of L-glutamic acid fermentation to a L-proline fermentation by Corynebacterium glutamicum
    • Nakanishi T, Yokote Y, Taketsugu Y (1973) Conversion of L-glutamic acid fermentation to a L-proline fermentation by Corynebacterium glutamicum . J Ferment Technol 51:742-749
    • (1973) J. Ferment Technol. , vol.51 , pp. 742-749
    • Nakanishi, T.1    Yokote, Y.2    Taketsugu, Y.3
  • 51
    • 45949128891 scopus 로고
    • Application of L-glutamate to L-proline fermentation by Corynebac terium acetoacidophilum
    • Nakanishi T, Hirao T, Azuma T, Sakurai M, Hagino H (1987) Application of L-glutamate to L-proline fermentation by Corynebac terium acetoacidophilum . J Ferment Technol 65: 139-144
    • (1987) J. Ferment Technol. , vol.65 , pp. 139-144
    • Nakanishi, T.1    Hirao, T.2    Azuma, T.3    Sakurai, M.4    Hagino, H.5
  • 52
    • 0034319243 scopus 로고    scopus 로고
    • Construction of a novel hydroxyproline-producing recombinant Escherichia coli by introducing a proline 4-hydroxylase gene
    • Shibasaki T, Hashimoto S, Mori H, Ozaki A (2000) Construction of a novel hydroxyproline-producing recombinant Escherichia coli by introducing a proline 4-hydroxylase gene. J Biosci Bioeng 90:522-525
    • (2000) J. Biosci Bioeng , vol.90 , pp. 522-525
    • Shibasaki, T.1    Hashimoto, S.2    Mori, H.3    Ozaki, A.4
  • 53
    • 84864146885 scopus 로고    scopus 로고
    • Microbial gems: Microorganisms without frontiers
    • Vandamme EJ (2007) Microbial gems: Microorganisms without frontiers. SIM News 57:81-90
    • (2007) SIM News , vol.57 , pp. 81-90
    • Vandamme, E.J.1
  • 54
    • 0034840608 scopus 로고    scopus 로고
    • Effect of transketolase modifications on carbon flow to the purine-nucleotide pathway in Corynebacterium ammoniagenes
    • Kamada N, Yasuhara A, Takano Y, Nakano T (2001) Effect of transketolase modifications on carbon flow to the purine-nucleotide pathway in Corynebacterium ammoniagenes . Appl Microbiol Biotechnol 56:710-717
    • (2001) Appl. Microbiol. Biotechnol. , vol.56 , pp. 710-717
    • Kamada, N.1    Yasuhara, A.2    Takano, Y.3    Nakano, T.4
  • 55
    • 0033947879 scopus 로고    scopus 로고
    • Production of ribo fl avin by metabolically engineered Corynebacterium ammoniagenes
    • Koizumi S, Yonetani Y, Maruyama A, Teshiba S (2000) Production of ribo fl avin by metabolically engineered Corynebacterium ammoniagenes . Appl Microbiol Biotechnol 51: 674-679
    • (2000) Appl. Microbiol. Biotechnol. , vol.51 , pp. 674-679
    • Koizumi, S.1    Yonetani, Y.2    Maruyama, A.3    Teshiba, S.4
  • 56
  • 58
    • 0034130561 scopus 로고    scopus 로고
    • Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays
    • Brenner S, Johnson M, Bridgham J, Golda G, Lloyd DH, Johnson D et al (2000) Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays. Nat Biotechnol 18:630-634
    • (2000) Nat. Biotechnol. , vol.18 , pp. 630-634
    • Brenner, S.1    Johnson, M.2    Bridgham, J.3    Golda, G.4    Lloyd, D.H.5    Johnson, D.6
  • 59
    • 4544372921 scopus 로고    scopus 로고
    • A genome wide transcription analysis of a fungal rivo flavin overproducer
    • Karos M, Vilarino C, Bollschweiler C, Revuelta JL (2004) A genome wide transcription analysis of a fungal rivo fl avin overproducer. J Biotechnol 113:69-76
    • (2004) J. Biotechnol. , vol.113 , pp. 69-76
    • Karos, M.1    Vilarino, C.2    Bollschweiler, C.3    Revuelta, J.L.4
  • 60
    • 0027479515 scopus 로고
    • Biotin biosyntheric pathway in a recombinant strain of Escherichia coli overexpressing bio genes: Evidence for a limiting step upstream from KAPA
    • Levy-Schil S, Debussche L, Rigault S, Soubrier F, Bacchette F, Lagneaux D et al (1993) Biotin biosyntheric pathway in a recombinant strain of Escherichia coli overexpressing bio genes: Evidence for a limiting step upstream from KAPA. Appl Microbiol Biotechnol 38:755-762
    • (1993) Appl. Microbiol. Biotechnol. , vol.38 , pp. 755-762
    • Levy-Schil, S.1    Debussche, L.2    Rigault, S.3    Soubrier, F.4    Bacchette, F.5    Lagneaux, D.6
  • 61
    • 0027935616 scopus 로고
    • Improvement of a d-biotinhyperproducing recombinant strain of Serratia marcescens
    • Sakurai N, Imai Y, Masuda M, Komatsubara S, Tosa T (1994) Improvement of a d-biotinhyperproducing recombinant strain of Serratia marcescens . J Biotechnol 36:63-73
    • (1994) J. Biotechnol. , vol.36 , pp. 63-73
    • Sakurai, N.1    Imai, Y.2    Masuda, M.3    Komatsubara, S.4    Tosa, T.5
  • 64
    • 0022372833 scopus 로고
    • Production of 2-keto- L-gulonate: An intermediate in L-ascorbate synthesis by a genetically modi fied Erwinia herbicola
    • Anderson S, Marks CB, Lazarus R, Miller J, Stafford K, Seymour J et al (1985) Production of 2-keto- L-gulonate: An intermediate in L-ascorbate synthesis by a genetically modified Erwinia herbicola . Science 230:144-149
    • (1985) Science , vol.230 , pp. 144-149
    • Anderson, S.1    Marks, C.B.2    Lazarus, R.3    Miller, J.4    Stafford, K.5    Seymour, J.6
  • 65
    • 0023762137 scopus 로고
    • Conversion of glucose to 2-keto-L-gulonate, an intermediate in L-ascorbate syn thesis by a recombinant strain of Erwinia citreus
    • Grindley JF, Payton MA, Van De Pol H, Hardy KG (1988) Conversion of glucose to 2-keto-L-gulonate, an intermediate in L-ascorbate synthesis, by a recombinant strain of Erwinia citreus . Appl Environ Microbiol 54: 1770-1775
    • (1988) Appl. Environ. Microbiol. , vol.54 , pp. 1770-1775
    • Grindley, J.F.1    Payton, M.A.2    Van De Pol, H.3    Hardy, K.G.4
  • 66
    • 0030894636 scopus 로고    scopus 로고
    • Cloning of genes coding for L-sorbose and L-sorbosone dehydrogenases from Gluconobacter oxydans and microbial production of 2-keto-gulonate, a precursor of L-ascorbic acid, in a recombinant G. oxydans strain
    • Saito Y, Ishii Y, Hayashi H, Imao Y, Akashi T, Yoshikawa K et al (1997) Cloning of genes coding for L-sorbose and L-sorbosone dehydrogenases from Gluconobacter oxydans and microbial production of 2-keto-gulonate, a precursor of L-ascorbic acid, in a recombinant G. oxydans strain. Appl Environ Microbiol 63:454-460
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 454-460
    • Saito, Y.1    Ishii, Y.2    Hayashi, H.3    Imao, Y.4    Akashi, T.5    Yoshikawa, K.6
  • 67
    • 0013047227 scopus 로고    scopus 로고
    • Vitamins and related biofactors, microbial production
    • Lederberg J (ed, 2nd edn. Academic, New York
    • DeBaets S, Vandedrinck S, Vandamme EJ (2000) Vitamins and related biofactors, microbial production. In: Lederberg J (ed) Encyclopedia of microbiology, vol 4, 2nd edn. Academic, New York, pp 837-853
    • (2000) Encyclopedia of microbiology , vol.4 , pp. 837-853
    • DeBaets, S.1    Vandedrinck, S.2    Vandamme, E.J.3
  • 70
  • 71
    • 0000959638 scopus 로고
    • Carotenoids
    • Peppler HJ, Perlman D (eds, 2nd edn. Academic, New York
    • Ninet L, Renaut J (1979) Carotenoids. In: Peppler HJ, Perlman D (eds) Microbial technology, vol 1, 2nd edn. Academic, New York, pp 529-544
    • (1979) Microbial Technology , vol.1 , pp. 529-544
    • Ninet, L.1    Renaut, J.2
  • 72
    • 0034787233 scopus 로고    scopus 로고
    • Metabolic engineering of isoprenoids
    • Barkovich R, Liao JC (2001) Metabolic engineering of isoprenoids. Metab Eng 3: 27-39
    • (2001) Metab. Eng. , vol.3 , pp. 27-39
    • Barkovich, R.1    Liao, J.C.2
  • 73
    • 0037209731 scopus 로고    scopus 로고
    • Metabolic engineering towards biotechnological production of carotenoids in microorganisms
    • Lee PC, Schmidt-Dannert C (2002) Metabolic engineering towards biotechnological production of carotenoids in microorganisms. Appl Microbiol Biotechnol 60:1-11
    • (2002) Appl. Microbiol. Biotechnol. , vol.60 , pp. 1-11
    • Lee, P.C.1    Schmidt-Dannert, C.2
  • 74
    • 13844254903 scopus 로고    scopus 로고
    • Directed evolution of copy number of a broad host range plasmid for metabolic engineering
    • Tao L, Jackson RE, Cheng Q (2005) Directed evolution of copy number of a broad host range plasmid for metabolic engineering. Metab Eng 7:10-17
    • (2005) Metab. Eng. , vol.7 , pp. 10-17
    • Tao, L.1    Jackson, R.E.2    Cheng, Q.3
  • 75
    • 33749249253 scopus 로고    scopus 로고
    • Characterization of lycopene-overproducing E coli strains in high cell density fermentations
    • Alper H, Miyaoku K, Stephanopoulos G (2006) Characterization of lycopene-overproducing E. coli strains in high cell density fermentations. Appl Microbiol Biotechnol 72:968-974
    • (2006) Appl. Microbiol. Biotechnol. , vol.72 , pp. 968-974
    • Alper, H.1    Miyaoku, K.2    Stephanopoulos, G.3
  • 77
    • 0032922650 scopus 로고    scopus 로고
    • Production of ketocarotenoids by microalgae
    • Margalith PZ (1999) Production of ketocarotenoids by microalgae. Appl Microbiol Biotechnol 51:431-438
    • (1999) Appl. Microbiol. Biotechnol. , vol.51 , pp. 431-438
    • Margalith, P.Z.1
  • 78
    • 0141958309 scopus 로고    scopus 로고
    • Phaf fi a rhodozyma: A colorful odyssey
    • Johnson EA (2003) Phaf fi a rhodozyma: A colorful odyssey. Int Microbiol 6:169-174
    • (2003) Int. Microbiol. , vol.6 , pp. 169-174
    • Johnson, E.A.1
  • 82
    • 66149134426 scopus 로고    scopus 로고
    • Metabolic regulation and overproduction of primary metabolites
    • Sánchez S, Demain AL (2008) Metabolic regulation and overproduction of primary metabolites. Microb Biotechnol 1:283-319
    • (2008) Microb. Biotechnol. , vol.1 , pp. 283-319
    • Sánchez, S.1    Demain, A.L.2
  • 85
    • 0037417864 scopus 로고    scopus 로고
    • Engineering the metabolism of Escherichia coli W3110 for the conversion of sugar to redox-neutral and oxidized products: Homoacetate production
    • Causey TB, Zhou S, Shanmugam KT, Ingram LO (2003) Engineering the metabolism of Escherichia coli W3110 for the conversion of sugar to redox-neutral and oxidized products: Homoacetate production. Proc Natl Acad Sci USA 100:825-832
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 825-832
    • Causey, T.B.1    Zhou, S.2    Shanmugam, K.T.3    Ingram, L.O.4
  • 86
    • 0028210599 scopus 로고
    • High concentrations of acetate with a mutant strain of C. thermoaceticum
    • Parekh SR, Cheryan M (1994) High concentrations of acetate with a mutant strain of C. thermoaceticum . Biotechnol Lett 16: 139-142
    • (1994) Biotechnol. Lett. , vol.16 , pp. 139-142
    • Parekh, S.R.1    Cheryan, M.2
  • 87
    • 0024586192 scopus 로고
    • Cloning of the membrane-bound aldehyde dehydrogenase gene of Acetobacter polyoxogenes and improvement of acetic acid production by use of thecloned gene
    • Fukaya M, Tayama K, Tamaki T, Tagami H, Okumura H, Kawamura Y et al (1989) Cloning of the membrane-bound aldehyde dehydrogenase gene of Acetobacter polyoxogenes and improvement of acetic acid production by use of thecloned gene. Appl Environ Microbiol 55:171-176
    • (1989) Appl. Environ. Microbiol. , vol.55 , pp. 171-176
    • Fukaya, M.1    Tayama, K.2    Tamaki, T.3    Tagami, H.4    Okumura, H.5    Kawamura, Y.6
  • 89
    • 47749114582 scopus 로고    scopus 로고
    • Genome shuf fl ing of Lactobacillus delbrueckii mutant and Bacillus amyloliquuefaciens through protoplastic fusion for L-latic acid production from starchy wastes
    • John RP, Gangadharan D, Madhavan Nampoothiri K (2008) Genome shuf fl ing of Lactobacillus delbrueckii mutant and Bacillus amyloliquuefaciens through protoplastic fusion for L-latic acid production from starchy wastes. Bioresour Technol 99:8008-8015
    • (2008) Bioresour. Technol. , vol.99 , pp. 8008-8015
    • John, R.P.1    Gangadharan, D.2    Madhavan Nampoothiri, K.3
  • 90
    • 2142811523 scopus 로고    scopus 로고
    • Lactic acid production by Rhizopus oryzae transformants with modified lactate dehydrogenase activity
    • Skory CD (2004) Lactic acid production by Rhizopus oryzae transformants with modified lactate dehydrogenase activity. Appl Microbiol Biotechnol 64:237-242
    • (2004) Appl. Microbiol. Biotechnol. , vol.64 , pp. 237-242
    • Skory, C.D.1
  • 91
    • 18444393083 scopus 로고    scopus 로고
    • Genetically engineered wine yeast produces a high concentration of L-lactic acid of extremely high optical purity
    • Saito S, Ishida N, Onishi T, Tokuhiro K, Nagamori E, Kitamoto K et al (2005) Genetically engineered wine yeast produces a high concentration of L-lactic acid of extremely high optical purity. Appl Environ Microbiol 71:2789-2792
    • (2005) Appl. Environ. Microbiol. , vol.71 , pp. 2789-2792
    • Saito, S.1    Ishida, N.2    Onishi, T.3    Tokuhiro, K.4    Nagamori, E.5    Kitamoto, K.6
  • 93
    • 28444472789 scopus 로고    scopus 로고
    • Fermentation of 10% (w/v) sugar to D(-)-lactate by engineered Escherichia coli B
    • Zhou S, Yomano LP, Shanmugam KT, Ingram LO (2003) Fermentation of 10% (w/v) sugar to D(-)-lactate by engineered Escherichia coli B. Biotechnol Lett 27:1891-1896
    • (2003) Biotechnol. Lett. , vol.27 , pp. 1891-1896
    • Zhou, S.1    Yomano, L.P.2    Shanmugam, K.T.3    Ingram, L.O.4
  • 95
    • 18944378749 scopus 로고    scopus 로고
    • Novel pathway engineering design of the anaerobic central metabolic pathway in Escherichia coli
    • Sánchez AM, Bennett GN, San KY (2005) Novel pathway engineering design of the anaerobic central metabolic pathway in Escherichia coli . Metab Eng 7:229-239
    • (2005) Metab. Eng. , vol.7 , pp. 229-239
    • Sánchez, A.M.1    Bennett, G.N.2    San, K.Y.3
  • 96
    • 33645029734 scopus 로고    scopus 로고
    • Genomebased metabolic engineering of Mannheimia succiniciproducens for succinic acid production
    • Lee SJ, Song H, Lee SY (2006) Genomebased metabolic engineering of Mannheimia succiniciproducens for succinic acid production. Appl Environ Microbiol 72:1939-1948
    • (2006) Appl. Environ. Microbiol. , vol.72 , pp. 1939-1948
    • Lee, S.J.1    Song, H.2    Lee, S.Y.3
  • 97
    • 19744367895 scopus 로고    scopus 로고
    • Fedbatch culture of a metabolically engineered Escherichia coli strain designed for high-level succinate production and yield under aerobic conditions
    • Lin H, Bennett GN, San KY (2005) Fedbatch culture of a metabolically engineered Escherichia coli strain designed for high-level succinate production and yield under aerobic conditions. Biotechnol Bioeng 90:775-779
    • (2005) Biotechnol. Bioeng. , vol.90 , pp. 775-779
    • Lin, H.1    Bennett, G.N.2    San, K.Y.3
  • 98
    • 0036309458 scopus 로고    scopus 로고
    • Succinate production in dual-phase Escherichia coli fermentations depends on the time of transition from aerobic to anaerobic conditions
    • Vemuri GN, Eiteman MA, Altman E (2002) Succinate production in dual-phase Escherichia coli fermentations depends on the time of transition from aerobic to anaerobic conditions. J Ind Microbiol Biotechnol 28: 325-332
    • (2002) J. Ind. Microbiol. Biotechnol. , vol.28 , pp. 325-332
    • Vemuri, G.N.1    Eiteman, M.A.2    Altman, E.3
  • 99
    • 77957583526 scopus 로고    scopus 로고
    • Metabolic engineering of Clostridium tyrobutyricum for butyric acid fermentation
    • San Diego, Abstract 70
    • Liu X, Yang S-T (2005) Metabolic engineering of Clostridium tyrobutyricum for butyric acid fermentation. Proceedings of the 229th ACS National Meeting, San Diego, Abstract 70
    • (2005) Proceedings of the 229th ACS National Meeting
    • Liu, X.1    Yang, S.-T.2
  • 100
    • 0026410778 scopus 로고
    • L-Malic acid formation by immobilized Saccharomyces cerevisiae ampli fi ed for fumarase
    • Neufeld RJ, Peleg Y, Rokem JS, Pines O, Goldberg I (1991) L-Malic acid formation by immobilized Saccharomyces cerevisiae ampli fi ed for fumarase. Enzyme Microb Technol 13:991-996
    • (1991) Enzyme Microb. Technol. , vol.13 , pp. 991-996
    • Neufeld, R.J.1    Peleg, Y.2    Rokem, J.S.3    Pines, O.4    Goldberg, I.5
  • 101
    • 0026636011 scopus 로고
    • Metabolic engineering of Candida tropicalis for the production of long-chain dicarboxylic acids
    • Picataggio S, Rohver T, Deander K, Lanning D, Reynolds R, Mielenz J et al (1992) Metabolic engineering of Candida tropicalis for the production of long-chain dicarboxylic acids. Nat Biotechnol 10:894-898
    • (1992) Nat. Biotechnol. , vol.10 , pp. 894-898
    • Picataggio, S.1    Rohver, T.2    Deander, K.3    Lanning, D.4    Reynolds, R.5    Mielenz, J.6
  • 102
    • 57649149334 scopus 로고    scopus 로고
    • Genome shuf fl ing to improve thermotolerance, ethanol tolerance and ethanol productivity of Saccharomyces cerevisiae
    • Shi DJ, Wang CL, Wang KM (2009) Genome shuf fl ing to improve thermotolerance, ethanol tolerance and ethanol productivity of Saccharomyces cerevisiae . J Ind Microbiol Biotechnol 36:139-147
    • (2009) J. Ind. Microbiol. Biotechnol. , vol.36 , pp. 139-147
    • Shi, D.J.1    Wang, C.L.2    Wang, K.M.3
  • 103
    • 34447286236 scopus 로고    scopus 로고
    • Genetic improvement of Saccharomyces cerevisiae for xylose fermentation
    • Chu BCH, Lee H (2007) Genetic improvement of Saccharomyces cerevisiae for xylose fermentation. Biotechnol Adv 25:425-441
    • (2007) Biotechnol. Adv. , vol.25 , pp. 425-441
    • Chu, B.C.H.1    Lee, H.2
  • 104
    • 33744914986 scopus 로고    scopus 로고
    • Engineering yeast for xylose metabolism
    • Jeffries TW (2006) Engineering yeast for xylose metabolism. Curr Opin Biotechnol 17:320-326
    • (2006) Curr. Opin. Biotechnol. , vol.17 , pp. 320-326
    • Jeffries, T.W.1
  • 105
    • 33644832381 scopus 로고    scopus 로고
    • In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production
    • Bro C, Regenberg B, Forster J, Nielsen J (2006) In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production. Metab Eng 8:102-111
    • (2006) Metab. Eng. , vol.8 , pp. 102-111
    • Bro, C.1    Regenberg, B.2    Forster, J.3    Nielsen, J.4
  • 106
    • 38749088716 scopus 로고    scopus 로고
    • Genome shuf fl ing in the ethanologenic yeast Candida krusei to improve acetic acid tolerance
    • Wei P, Li Z, He P, Lin Y, Jiang N (2008) Genome shuf fl ing in the ethanologenic yeast Candida krusei to improve acetic acid tolerance. Biotechnol Appl Biochem 49:113-120
    • (2008) Biotechnol. Appl. Biochem. , vol.49 , pp. 113-120
    • Wei, P.1    Li, Z.2    He, P.3    Lin, Y.4    Jiang, N.5
  • 108
    • 0001574949 scopus 로고
    • Fermentation of crystalline cellulose to ethanol by Klebsiella oxytoca containing chromosomally integrated Zymomonas mobilis genes
    • Doran JB, Ingram LO (1993) Fermentation of crystalline cellulose to ethanol by Klebsiella oxytoca containing chromosomally integrated Zymomonas mobilis genes. Biotechnol Prog 9:533-538
    • (1993) Biotechnol. Prog. , vol.9 , pp. 533-538
    • Doran, J.B.1    Ingram, L.O.2
  • 109
    • 0034040510 scopus 로고    scopus 로고
    • Development of new ethanologenic Escherichia coli strains for fermentation of lignocellulosic biomass
    • Dien BS, Nichols NN, O'Bryan PJ, Bothast RJ (2000) Development of new ethanologenic Escherichia coli strains for fermentation of lignocellulosic biomass. Appl Biochem Biotechnol 84(86):181-196
    • (2000) Appl. Biochem. Biotechnol. , vol.84 , Issue.86 , pp. 181-196
    • Dien, B.S.1    Nichols, N.N.2    O'Bryan, P.J.3    Bothast, R.J.4
  • 110
    • 0033967647 scopus 로고    scopus 로고
    • High production of 1,3-propanediol from industrial glycerol by a newly isolated Clostridium butyricum strain
    • Papanikolaou S, Ruiz-Sánchez P, Pariset B, Blanchard F, Fick M (2000) High production of 1,3-propanediol from industrial glycerol by a newly isolated Clostridium butyricum strain. J Biotechnol 77:191-208
    • (2000) J. Biotechnol. , vol.77 , pp. 191-208
    • Papanikolaou, S.1    Ruiz-Sánchez, P.2    Pariset, B.3    Blanchard, F.4    Fick, M.5
  • 111
    • 0742286881 scopus 로고    scopus 로고
    • Pathway engineering through rational design tutorial: Designing and building cell factories for biobased production
    • Sanford K, Valle F, Ghirnikar R (2004) Pathway engineering through rational design. Tutorial: Designing and building cell factories for biobased production. Genet Eng News 24:44-45
    • (2004) Genet. Eng. News , vol.24 , pp. 44-45
    • Sanford, K.1    Valle, F.2    Ghirnikar, R.3
  • 112
    • 0142027026 scopus 로고    scopus 로고
    • Metabolic engineering for the microbial production of 1,3 propanediol
    • Nakamura C, Whited G (2003) Metabolic engineering for the microbial production of 1,3 propanediol. Curr Opin Biotechnol 14:454-459
    • (2003) Curr. Opin. Biotechnol. , vol.14 , pp. 454-459
    • Nakamura, C.1    Whited, G.2
  • 113
    • 2442587515 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli: Construction of an Efficient biocatalyst for D-mannitolformationinawhole-cellbiotransformation
    • Kaup B, Bringer-Meyer S, Sahm H (2004) Metabolic engineering of Escherichia coli: Construction of an Efficient biocatalyst for D-mannitolformationinawhole-cellbiotransformation. Appl Microbiol Biotechnol 64:333-339
    • (2004) Appl. Microbiol. Biotechnol. , vol.64 , pp. 333-339
    • Kaup, B.1    Bringer-Meyer, S.2    Sahm, H.3
  • 114
    • 28444455948 scopus 로고    scopus 로고
    • D-Mannitol formation from D-glucose in a whiole-cell biotransformation with recombinant Escherichia coli
    • Kaup B, Bringer-Meyer S, Sahm H (2005) D-Mannitol formation from D-glucose in a whiole-cell biotransformation with recombinant Escherichia coli . Appl Microbiol Biotechnol 69:397-403
    • (2005) Appl. Microbiol. Biotechnol. , vol.69 , pp. 397-403
    • Kaup, B.1    Bringer-Meyer, S.2    Sahm, H.3
  • 115
    • 33846149708 scopus 로고    scopus 로고
    • Ca2+ and Cu2+ supplementation increases mannitol production by Candida magnoliae
    • Lee J-K, Oh D-K, Song H-Y, Kim I-W (2007) Ca2+ and Cu2+ supplementation increases mannitol production by Candida magnoliae . Biotechnol Lett 29:291-294
    • (2007) Biotechnol. Lett. , vol.29 , pp. 291-294
    • Lee, J.-K.1    Oh, D.-K.2    Song, H.-Y.3    Kim, I.-W.4
  • 116
    • 68349121585 scopus 로고    scopus 로고
    • Recent advances in the biological production of mannitol
    • Song SH, Vieille C (2009) Recent advances in the biological production of mannitol. Appl Microbiol Biotechnol 84:55-62
    • (2009) Appl. Microbiol. Biotechnol. , vol.84 , pp. 55-62
    • Song, S.H.1    Vieille, C.2
  • 117
    • 0002292801 scopus 로고
    • The simultaneous production of sorbitol and gluconic acid by Zymomonas mobilis
    • Chun UH, Rogers PL (1988) The simultaneous production of sorbitol and gluconic acid by Zymomonas mobilis . Appl Microbiol Biotechnol 29:19-24
    • (1988) Appl. Microbiol. Biotechnol. , vol.29 , pp. 19-24
    • Chun, U.H.1    Rogers, P.L.2
  • 118
    • 33947431635 scopus 로고    scopus 로고
    • High-level; production of the low-calorie sugar sorbitol by Lactobacillus plantarum through metyabolic engineering
    • Ladero V, Ramos A, Wiersma A, Gof fi n P, Schanck A, Kleerbezem M (2007) High-level; production of the low-calorie sugar sorbitol by Lactobacillus plantarum through metyabolic engineering. Appl Environ Microbiol 73:1864-1872
    • (2007) Appl. Environ. Microbiol. , vol.73 , pp. 1864-1872
    • Ladero, V.1    Ramos, A.2    Wiersma, A.3    Goffin, P.4    Schanck, A.5    Kleerbezem, M.6
  • 120
    • 0026926475 scopus 로고
    • Application of continuous substrate feeding to the ABE fermentation: Relief of product inhibition using extraction, perstraction, stripping and pervaporation
    • Qureshi N, Maddox IS, Freidl A (1992) Application of continuous substrate feeding to the ABE fermentation: Relief of product inhibition using extraction, perstraction, stripping and pervaporation. Biotechnol Prog 8:382-390
    • (1992) Biotechnol. Prog. , vol.8 , pp. 382-390
    • Qureshi, N.1    Maddox, I.S.2    Freidl, A.3
  • 121
    • 0032868399 scopus 로고    scopus 로고
    • Acetate enhances solvent production and prevents degeneration in Clostridium beijerinckii BA101
    • Chen C-K, Blaschek HP (1999) Acetate enhances solvent production and prevents degeneration in Clostridium beijerinckii BA101. Appl Microbiol Biotechnol 52: 170-173
    • (1999) Appl. Microbiol. Biotechnol. , vol.52 , pp. 170-173
    • Chen, C.-K.1    Blaschek, H.P.2
  • 122
    • 67649771820 scopus 로고    scopus 로고
    • Microbial production of advanced transportation fuels in non-natural hosts
    • Connor MR, Liao JC (2009) Microbial production of advanced transportation fuels in non-natural hosts. Curr Opin Biotechnol 20:307-315
    • (2009) Curr. Opin. Biotechnol. , vol.20 , pp. 307-315
    • Connor, M.R.1    Liao, J.C.2
  • 123
    • 35148889024 scopus 로고    scopus 로고
    • Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity
    • Whiters ST, Gottlieb SS, Lieu B, Newman JD, Keasling JD (2007) Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity. Appl Environ Microbiol 73:6277-6283
    • (2007) Appl. Environ. Microbiol. , vol.73 , pp. 6277-6283
    • Whiters, S.T.1    Gottlieb, S.S.2    Lieu, B.3    Newman, J.D.4    Keasling, J.D.5
  • 124
    • 38049001166 scopus 로고    scopus 로고
    • Nonfermentative pathways for synthesis of branched-chain higher alcohols as biofuels
    • Atsumi S, Hanai T, Liao JC (2008) Nonfermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature 451:86-89
    • (2008) Nature , vol.451 , pp. 86-89
    • Atsumi, S.1    Hanai, T.2    Liao, J.C.3
  • 127
    • 0034646538 scopus 로고    scopus 로고
    • Pathways of discovery: Infectious history
    • Lederberg J (2000) Pathways of discovery: Infectious history. Science 288:287-293
    • (2000) Science , vol.288 , pp. 287-293
    • Lederberg, J.1
  • 128
    • 77957567131 scopus 로고    scopus 로고
    • Strain improvement of clavulanic acid producing Streptomyces clavuligerus
    • ISBA), Beijing, Abstr
    • Choi KP, Kim KH, Kim JW (1997) Strain improvement of clavulanic acid producing Streptomyces clavuligerus . Proc 10th Internat Symp Biol Actinomycetes (ISBA), Beijing, Abstr 12, 9
    • (1997) Proc 10th Internat Symp Biol Actinomycetes , vol.12 , pp. 9
    • Choi, K.P.1    Kim, K.H.2    Kim, J.W.3
  • 129
    • 33646082272 scopus 로고    scopus 로고
    • Rational strain improvement for enhanced clavulanic acid production by genetic engineering of the glycolytic pathway in Streptomyces clavuligerus
    • Li R, Townsend CA (2006) Rational strain improvement for enhanced clavulanic acid production by genetic engineering of the glycolytic pathway in Streptomyces clavuligerus . Metab Eng 8:240-252
    • (2006) Metab. Eng. , vol.8 , pp. 240-252
    • Li, R.1    Townsend, C.A.2
  • 130
    • 0345440126 scopus 로고    scopus 로고
    • Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: Evidence for two different genes in formation of the C3 unit
    • Pérez-Redondo RA, Rodríguez-García A, Martín JF, Liras P (1999) Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: Evidence for two different genes in formation of the C3 unit. J Bacteriol 181:6922-6928
    • (1999) J. Bacteriol. , vol.181 , pp. 6922-6928
    • Pérez-Redondo, R.A.1    Rodríguez-García, A.2    Martín, J.F.3    Liras, P.4
  • 131
    • 0031891879 scopus 로고    scopus 로고
    • A pathway-specific transcriptional activator regulates late steps of clavuklanic acid biosynthesis in Streptomyces clavuligerus
    • Paradkar AS, Aiodoo KA, Jensen SE (1998) A pathway-specific transcriptional activator regulates late steps of clavuklanic acid biosynthesis in Streptomyces clavuligerus . Mol Microbiol 27:831-843
    • (1998) Mol. Microbiol. , vol.27 , pp. 831-843
    • Paradkar, A.S.1    Aiodoo, K.A.2    Jensen, S.E.3
  • 132
    • 0030954966 scopus 로고    scopus 로고
    • A regulatory gene (ccaR ) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: Amplification results in overproduction of both α?-lactam compounds
    • Pérez-Llarena FJ, Liras P, Rodríguez-García A, Martín JF (1997) A regulatory gene (ccaR ) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: Amplification results in overproduction of both α?-lactam compounds. J Bacteriol 179: 2053-2059
    • (1997) J. Bacteriol. , vol.179 , pp. 2053-2059
    • Pérez-Llarena, F.J.1    Liras, P.2    Rodríguez-García, A.3    Martín, J.F.4
  • 134
    • 0029995755 scopus 로고    scopus 로고
    • γ?-( L-α-Aminoadipyl)- L-cysteinyl- D-valine synthetase is a rate limiting enzyme for penicillin production in Aspergillus nidulans
    • Kennedy J, Turner G (1996) γ?-( L-α-Aminoadipyl)- L-cysteinyl- D-valine synthetase is a rate limiting enzyme for penicillin production in Aspergillus nidulans . Mol Gen Genet 253:189-197
    • (1996) Mol. Gen. Genet. , vol.253 , pp. 189-197
    • Kennedy, J.1    Turner, G.2
  • 135
    • 0013543369 scopus 로고
    • Recombination studies with Cephalosporium acremonium
    • Sebek OK, Laskin AI (eds. American Society for Microbiology, Washington DC
    • Hamlyn PF, Ball C (1979) Recombination studies with Cephalosporium acremonium . In: Sebek OK, Laskin AI (eds) Genetics of industrial microorganisms. American Society for Microbiology, Washington, DC, pp 185-191
    • (1979) Genetics of Industrial Microorganisms , pp. 185-191
    • Hamlyn, P.F.1    Ball, C.2
  • 136
    • 33644966417 scopus 로고
    • Improved transformation of Cephalosporium acremonium
    • Alacevic M, Hranueli D, Toman Z (eds, part B. Zagreb, Pliva
    • Skatrud PL, Fisher DL, Ingolia TD, Queener SW (1987) Improved transformation of Cephalosporium acremonium . In: Alacevic M, Hranueli D, Toman Z (eds) Genetics of industrial microorganisms, part B. Zagreb, Pliva, pp 111-119
    • (1987) Genetics of Industrial Microorganisms , pp. 111-119
    • Skatrud, P.L.1    Fisher, D.L.2    Ingolia, T.D.3    Queener, S.W.4
  • 138
    • 0342967062 scopus 로고
    • Strain improvement by genetic recombination of cephamycin producers nocardia lactamdurans and Streptomyces griseus
    • Wesseling AC, Lago B (1981) Strain improvement by genetic recombination of cephamycin producers, Nocardia lactamdurans and Streptomyces griseus . Dev Ind Microbiol 22:641-651
    • (1981) Dev. Ind. Microbiol. , vol.22 , pp. 641-651
    • Wesseling, A.C.1    Lago, B.2
  • 139
    • 0034108566 scopus 로고    scopus 로고
    • Overexpression of the lat gene in Nocardia lactamdurans from strong heterologous promoters results in very high levels of lysine-6-aminotransferase and up to a two-fold increase in cephamycin C production
    • Chary VK, De La Fuente JL, Leitao AL, Liras P, Martín JF (2000) Overexpression of the lat gene in Nocardia lactamdurans from strong heterologous promoters results in very high levels of lysine-6-aminotransferase and up to a two-fold increase in cephamycin C production. Appl Microbiol Biotechnol 53:282-288
    • (2000) Appl. Microbiol. Biotechnol. , vol.53 , pp. 282-288
    • Chary, V.K.1    De La Fuente, J.L.2    Leitao, A.L.3    Liras, P.4    Martín, J.F.5
  • 140
    • 16244415184 scopus 로고    scopus 로고
    • Expression of ccaR encoding the positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus is dependent on bldG
    • Bignell DRD, Tahlan K, Colvin KR, Jensen SE, Leskiw BK (2005) Expression of ccaR encoding the positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus is dependent on bldG . Antimicrob Agents Chemother 49:1529-1541
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 1529-1541
    • Bignell, D.R.D.1    Tahlan, K.2    Colvin, K.R.3    Jensen, S.E.4    Leskiw, B.K.5
  • 142
    • 0028835709 scopus 로고
    • Production of cephalosporin intermediates by feeding adipic acid to recombinant Penicillium chrysogenum strains expressing ring expansion activity
    • Crawford L, Stepan AM, Mcada PC, Rambosek JA, Conder MJ, Vinci VA et al (1995) Production of cephalosporin intermediates by feeding adipic acid to recombinant Penicillium chrysogenum strains expressing ring expansion activity. Nat Biotechnol 13:58-62
    • (1995) Nat. Biotechnol. , vol.13 , pp. 58-62
    • Crawford, L.1    Stepan, A.M.2    Mcada, P.C.3    Rambosek, J.A.4    Conder, M.J.5    Vinci, V.A.6
  • 143
    • 0033898359 scopus 로고    scopus 로고
    • Environmentally safe production of 7-aminodeacetoxycephalosporanic acid (7ADCA) using recombinant strains of Acremonium chrysogenum
    • Velasco J, Adrio JL, Moreno MA, Díez B, Soler G, Barredo JL (2000) Environmentally safe production of 7-aminodeacetoxycephalosporanic acid (7ADCA) using recombinant strains of Acremonium chrysogenum . Nat Biotechnol 18:857-861
    • (2000) Nat. Biotechnol. , vol.18 , pp. 857-861
    • Velasco, J.1    Adrio, J.L.2    Moreno, M.A.3    Díez, B.4    Soler, G.5    Barredo, J.L.6
  • 144
    • 7544240471 scopus 로고    scopus 로고
    • Cloning and co-expression of D-amino acid oxidase and glutaryl-7-aminocephalosporanic acid acylase genes in Escherichia coli
    • Luo H, Yu H, Qiang L, Shen Z (2004) Cloning and co-expression of D-amino acid oxidase and glutaryl-7-aminocephalosporanic acid acylase genes in Escherichia coli . Enzyme Microb Technol 35:514-518
    • (2004) Enzyme Microb. Technol. , vol.35 , pp. 514-518
    • Luo, H.1    Yu, H.2    Qiang, L.3    Shen, Z.4
  • 145
  • 147
    • 76649138924 scopus 로고    scopus 로고
    • Genetic engineering of macrolide biosyn thesis past advances, current state and future prospects
    • Park SR, Han AR, Ban Y-H, Yoo YJ, Kim EJ et al (2010) Genetic engineering of macrolide biosynthesis: Past advances, current state and future prospects. Appl Microbiol Biotechnol 85:1227-1239
    • (2010) Appl. Microbiol. Biotechnol. , vol.85 , pp. 1227-1239
    • Park, S.R.1    Han, A.R.2    Ban, Y.-H.3    Yoo, Y.J.4    Kim, E.J.5
  • 148
    • 4544297816 scopus 로고    scopus 로고
    • Engineering precursor flow for increased erythromycin production in Aeromicrobium erythreum
    • Reeves AR, Cernota WH, Brikun IA, Wesley RK, Weber JM (2004) Engineering precursor flow for increased erythromycin production in Aeromicrobium erythreum . Metab Eng 6:300-312
    • (2004) Metab. Eng. , vol.6 , pp. 300-312
    • Reeves, A.R.1    Cernota, W.H.2    Brikun, I.A.3    Wesley, R.K.4    Weber, J.M.5
  • 149
    • 0030039759 scopus 로고    scopus 로고
    • Transposition mutagenesis in Streptomyces fradiae: Identification of a neutral site for the stable insertion of DNA by transposon exchange
    • Solenberg PJ, Cantwell CA, Tietz AJ, McGilvray D, Queener SW, Baltz RH (1996) Transposition mutagenesis in Streptomyces fradiae: Identification of a neutral site for the stable insertion of DNA by transposon exchange. Gene 16:67-72
    • (1996) Gene. , vol.16 , pp. 67-72
    • Solenberg, P.J.1    Cantwell, C.A.2    Tietz, A.J.3    McGilvray, D.4    Queener, S.W.5    Baltz, R.H.6
  • 151
    • 34447524208 scopus 로고    scopus 로고
    • Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis
    • Galm U, Shen B (2006) Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis. Expet Opin Drug Discov 1:409-437
    • (2006) Expet Opin. Drug Discov. , vol.1 , pp. 409-437
    • Galm, U.1    Shen, B.2
  • 152
    • 0141513836 scopus 로고    scopus 로고
    • On the generation of novel anticancer drugs by recombinant DNA technology: The use of combinatorial biosynthesis to produce novel drugs
    • Méndez C, Salas JA (2003) On the generation of novel anticancer drugs by recombinant DNA technology: The use of combinatorial biosynthesis to produce novel drugs. Comb Chem High Throughput Screen 6:513-526
    • (2003) Comb. Chem. High Throughput Screen , vol.6 , pp. 513-526
    • Méndez, C.1    Salas, J.A.2
  • 153
    • 0034788156 scopus 로고    scopus 로고
    • Combinatorial biosynthesis of antimicrobials and other natural products
    • Rodríguez E, McDaniel R (2001) Combinatorial biosynthesis of antimicrobials and other natural products. Curr Opin Microbiol 4: 526-534
    • (2001) Curr. Opin. Microbiol. , vol.4 , pp. 526-534
    • Rodríguez, E.1    McDaniel, R.2
  • 154
    • 0037140766 scopus 로고    scopus 로고
    • Rationally designed glycosylated premithramycins: Hybrid aromatic polyketides using genes from three different biosynthetic pathways
    • Trefzer A, Blanco G, Remsing L, Kunzel E, Rix U, Lipata F et al (2002) Rationally designed glycosylated premithramycins: Hybrid aromatic polyketides using genes from three different biosynthetic pathways. J Am Chem Soc 124:6056-6062
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 6056-6062
    • Trefzer, A.1    Blanco, G.2    Remsing, L.3    Kunzel, E.4    Rix, U.5    Lipata, F.6
  • 155
    • 0021744397 scopus 로고
    • Isolation and structure of a new antibiotic, indolizomycin, produced by a strain SK2-52 obtained by interspecies fusion treatment
    • Gomi S, Ikeda D, Nakamura H, Naganawa H, Yamashita F, Hotta K et al (1984) Isolation and structure of a new antibiotic, indolizomycin, produced by a strain SK2-52 obtained by interspecies fusion treatment. J Antibiot 37:1491-1494
    • (1984) J. Antibiot , vol.37 , pp. 1491-1494
    • Gomi, S.1    Ikeda, D.2    Nakamura, H.3    Naganawa, H.4    Yamashita, F.5    Hotta, K.6
  • 156
    • 0019989586 scopus 로고
    • 16, 17-dihydrorifamycin S and 16,17-dihydro-17-hydroxyrifamycin S, two novel rifamycins from a recombinant strain C5/42 of Nocardia mediterranei
    • Traxler P, Schupp T, Wehrli W (1982) 16, 17-dihydrorifamycin S and 16,17-dihydro-17-hydroxyrifamycin S, two novel rifamycins from a recombinant strain C5/42 of Nocardia mediterranei . J Antibiot 35:594-601
    • (1982) J. Antibiot. , vol.35 , pp. 594-601
    • Traxler, P.1    Schupp, T.2    Wehrli, W.3
  • 157
    • 0029913557 scopus 로고    scopus 로고
    • Variety of hybrid characters among recombinants obtained by interspecific protoplast fusion in streptomycetes
    • Okanishi M, Suzuki N, Furuta T (1996) Variety of hybrid characters among recombinants obtained by interspecific protoplast fusion in streptomycetes. Biosci Biotechnol Biochem 60:1233-1238
    • (1996) Biosci. Biotechnol. Biochem. , vol.60 , pp. 1233-1238
    • Okanishi, M.1    Suzuki, N.2    Furuta, T.3
  • 158
    • 0033610483 scopus 로고    scopus 로고
    • Engineering a methymycin/pikromycin-calicheamicin hybrid: Construction of two new macrolides carrying a designed sugar moiety
    • Zhou L, Ahlert J, Xue Y, Thorson JS, Sherman DH, Liu H-W (1999) Engineering a methymycin/pikromycin-calicheamicin hybrid: Construction of two new macrolides carrying a designed sugar moiety. J Am Chem Soc 121:9881-9882
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 9881-9882
    • Zhou, L.1    Ahlert, J.2    Xue, Y.3    Thorson, J.S.4    Sherman, D.H.5    Liu, H.-W.6
  • 159
    • 0035501490 scopus 로고    scopus 로고
    • Altering the glycosylation pattern of bioactive compounds
    • Méndez C, Salas JA (2001) Altering the glycosylation pattern of bioactive compounds. Trends Biotechnol 19:449-456
    • (2001) Trends Biotechnol. , vol.19 , pp. 449-456
    • Méndez, C.1    Salas, J.A.2
  • 160
    • 0027221459 scopus 로고
    • Transcriptional analysis of the Streptomyces glaucescens tetracenomycin biosynthesis gene cluster
    • Decker H, Hutchinson CR (1993) Transcriptional analysis of the Streptomyces glaucescens tetracenomycin biosynthesis gene cluster. J Bacteriol 175:3887-3892
    • (1993) J. Bacteriol. , vol.175 , pp. 3887-3892
    • Decker, H.1    Hutchinson, C.R.2
  • 161
    • 0032556233 scopus 로고    scopus 로고
    • Novel hybrid tetracenomycins through combinatorial biosynthesis using a glycosyltransferase encoded by the elm genes in cosmid 16 F4 which shows a very broad sugar substrate specificity
    • Wohlert S-E, Blanco G, Lombo F, Fernández E, Brana AF, Reich S, Udvarnoki G, Méndez C, Decker H, Frevert J et al (1998) Novel hybrid tetracenomycins through combinatorial biosynthesis using a glycosyltransferase encoded by the elm genes in cosmid 16 F4 which shows a very broad sugar substrate specificity. J Am Chem Soc 120: 10596-10601
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 10596-10601
    • Wohlert, S.-E.1    Blanco, G.2    Lombo, F.3    Fernández, E.4    Brana, A.F.5    Reich, S.6    Udvarnoki, G.7    Méndez, C.8    Decker, H.9    Frevert, J.10
  • 163
    • 48349146354 scopus 로고    scopus 로고
    • Evolution of Streptomyces pristinaespiralis for resistance and production of pristinamycin by genome shuf fl ing
    • Xu B, Jin Z, Wang H, Jin Q, Jin X et al (2008) Evolution of Streptomyces pristinaespiralis for resistance and production of pristinamycin by genome shuf fl ing. Appl Microbiol Biotechnol 80:261-267
    • (2008) Appl. Microbiol. Biotechnol. , vol.80 , pp. 261-267
    • Xu, B.1    Jin, Z.2    Wang, H.3    Jin, Q.4    Jin, X.5
  • 164
    • 33744533954 scopus 로고    scopus 로고
    • Microbial genomics for the improvement of natural product discovery
    • Van Lanen SG, Shen B (2006) Microbial genomics for the improvement of natural product discovery. Curr Opin Microbiol 9:252-260
    • (2006) Curr. Opin. Microbiol. , vol.9 , pp. 252-260
    • Van Lanen, S.G.1    Shen, B.2
  • 166
  • 168
    • 64249144646 scopus 로고    scopus 로고
    • Microbial prescreens for anticancer activity
    • Newman DJ, Shapiro S (2008) Microbial prescreens for anticancer activity. SIM News 58:132-150
    • (2008) SIM News , vol.58 , pp. 132-150
    • Newman, D.J.1    Shapiro, S.2
  • 169
    • 0029008896 scopus 로고
    • Expression of Streptomyces peucetius genes for doxorubicin resistance and aklavinone 11-hydroxylase in Streptomyces galilaeus ATCC 31133 and production of a hybrid aclacinomycin
    • Hwang CK, Kim HS, Hong YS, Kim YH, Hong SK, Kim SJ, Lee JJ (1995) Expression of Streptomyces peucetius genes for doxorubicin resistance and aklavinone 11-hydroxylase in Streptomyces galilaeus ATCC 31133 and production of a hybrid aclacinomycin. Antimicrob Agents Chemother 39: 1616-1620
    • (1995) Antimicrob. Agents Chemother , vol.39 , pp. 1616-1620
    • Hwang, C.K.1    Kim, H.S.2    Hong, Y.S.3    Kim, Y.H.4    Hong, S.K.5    Kim, S.J.6    Lee, J.J.7
  • 170
    • 0029873060 scopus 로고    scopus 로고
    • New anthracycline metabolites produced by the aklavinone 11-hydroxylase gene in Streptomyces galilaeus ATCC 3113
    • Kim HS, Hong YS, Kim YH, Yoo OJ, Lee JJ (1996) New anthracycline metabolites produced by the aklavinone 11-hydroxylase gene in Streptomyces galilaeus ATCC 3113. J Antibiot 49:355-360
    • (1996) J. Antibiot , vol.49 , pp. 355-360
    • Kim, H.S.1    Hong, Y.S.2    Kim, Y.H.3    Yoo, O.J.4    Lee, J.J.5
  • 171
    • 0029044853 scopus 로고
    • Nucleotide sequences and expression of genes from Streptomyces purpurascens that cause the production of new anthracyclines
    • Niemi J, Mäntäslä P (1995) Nucleotide sequences and
    • (1995) J. Bacteriol. , vol.177 , pp. 2942-2945
    • Niemi, J.1    Mäntäslä, P.2
  • 172
    • 0029820116 scopus 로고    scopus 로고
    • Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes
    • Ylihonko K, Hakala J, Kunnari T, Mäntsälä P (1996) Production of hybrid anthracycline antibiotics by heterologous expression of Streptomyces nogalater nogalamycin biosynthesis genes. Microbiology 142:1965-1972
    • (1996) Microbiology , vol.142 , pp. 1965-1972
    • Ylihonko, K.1    Hakala, J.2    Kunnari, T.3    Mäntsälä, P.4
  • 173
    • 0026141803 scopus 로고
    • Expression of polyketide biosynthesis and regulatory genes in heterologous streptomycetes
    • Strohl WR, Bartel PL, Li Y, Connors NC, Woodman RH (1991) Expression of polyketide biosynthesis and regulatory genes in heterologous streptomycetes. J Ind Microbiol 7:163-174
    • (1991) J. Ind. Microbiol. , vol.7 , pp. 163-174
    • Strohl, W.R.1    Bartel, P.L.2    Li, Y.3    Connors, N.C.4    Woodman, R.H.5
  • 174
    • 0024996111 scopus 로고
    • Biosynthesis of anthraquinones by interspecies cloning of actinorhodin genes in streptomycetes: Clari fi cation of actinorhodin gene functions
    • Bartel PL, Zhu CB, Lampel JS, Dosch DC, Connors NC, Strohl WR, Beale JM Jr, Floss HG (1990) Biosynthesis of anthraquinones by interspecies cloning of actinorhodin genes in streptomycetes: Clari fi cation of actinorhodin gene functions. J Bacteriol 172: 4816-4826
    • (1990) J. Bacteriol. , vol.172 , pp. 4816-4826
    • Bartel, P.L.1    Zhu, C.B.2    Lampel, J.S.3    Dosch, D.C.4    Connors, N.C.5    Strohl, W.R.6    Beale Jr., J.M.7    Floss, H.G.8
  • 177
    • 0021229643 scopus 로고
    • Taxol: An antimitotic agent with a new mechanism of action
    • Manfredi JJ, Horowitz SB (1984) Taxol: An antimitotic agent with a new mechanism of action. Pharmacol Ther 25:83-125
    • (1984) Pharmacol. Ther. , vol.25 , pp. 83-125
    • Manfredi, J.J.1    Horowitz, S.B.2
  • 178
    • 0028708677 scopus 로고
    • Taxol (paclitaxel): Mechanisms of action
    • Horwitz SB (1994) Taxol (paclitaxel): Mechanisms of action. Ann Oncol 5(Suppl 6): S3-S6
    • (1994) Ann. Oncol. , vol.5 , Issue.SUPPL6
    • Horwitz, S.B.1
  • 180
    • 44749083814 scopus 로고    scopus 로고
    • Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production
    • Engels B, Dahm P, Jennewein S (2008) Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production. Metab Eng 10: 201-206
    • (2008) Metab. Eng. , vol.10 , pp. 201-206
    • Engels, B.1    Dahm, P.2    Jennewein, S.3
  • 181
    • 0036998727 scopus 로고    scopus 로고
    • Epothilones: New tubulin polymerization agents in preclinical and clinical development
    • Borzlleri RM, Vite GD (2002) Epothilones: New tubulin polymerization agents in preclinical and clinical development. Drugs Future 27:1149-1163
    • (2002) Drugs Future , vol.27 , pp. 1149-1163
    • Borzlleri, R.M.1    Vite, G.D.2
  • 182
    • 0016913421 scopus 로고
    • Crystal and molecular structure of compactin: A new antifungal metabolite from Penicillium brevicompactum
    • Brown AG, Smale TC, King TJ, Hasenkamp R, Thompson RH (1976) Crystal and molecular structure of compactin: A new antifungal metabolite from Penicillium brevicompactum . J Chem Soc Perkin Trans I (11):1165-1170
    • (1976) J. Chem. Soc. Perkin Trans. I , Issue.11 , pp. 1165-1170
    • Brown, A.G.1    Smale, T.C.2    King, T.J.3    Hasenkamp, R.4    Thompson, R.H.5
  • 183
    • 0017055252 scopus 로고
    • ML-236B and ML-236 C, new inhibitors of cholesterolgenesis produced by Penicillium citrinun
    • Endo A, Kuroda M, Tsujita Y (1976) ML-236B and ML-236 C, new inhibitors of cholesterolgenesis produced by Penicillium citrinun . J Antibiot 29:1346-1348
    • (1976) J. Antibiot. , vol.29 , pp. 1346-1348
    • Endo, A.1    Kuroda, M.2    Tsujita, Y.3
  • 184
    • 0018592266 scopus 로고
    • Monacolin K, a new hypocholesterolemic agent produced by Monascus species
    • Endo A (1979) Monacolin K, a new hypocholesterolemic agent produced by Monascus species. J Antibiot 32:852-854
    • (1979) J. Antibiot. , vol.32 , pp. 852-854
    • Endo, A.1
  • 185
    • 0018939225 scopus 로고
    • Mevinolin: A highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent
    • Alberts AW, Chen J, Kuron G, Hunt V, Huff J, Hoffman C et al (1980) Mevinolin: A highly potent competitive inhibitor of hydroxymethylglutaryl- coenzyme A reductase and a cholesterol-lowering agent. Proc Natl Acad Sci USA 77:3957-3961
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 3957-3961
    • Alberts, A.W.1    Chen, J.2    Kuron, G.3    Hunt, V.4    Huff, J.5    Hoffman, C.6
  • 186
    • 0037316031 scopus 로고    scopus 로고
    • Integrating transcriptional and metabolite pro fi les to direct the engineering of lovastatin-producing fungal strains
    • Askenazi M, Driggers EM, Holtzman DA, Norman TC, Iverson S, Zimmer DP et al (2003) Integrating transcriptional and metabolite pro fi les to direct the engineering of lovastatin-producing fungal strains. Nat Biotechnol 21:150-156
    • (2003) Nat. Biotechnol. , vol.21 , pp. 150-156
    • Askenazi, M.1    Driggers, E.M.2    Holtzman, D.A.3    Norman, T.C.4    Iverson, S.5    Zimmer, D.P.6
  • 187
    • 0009524443 scopus 로고
    • Avermectins, antiparasitic lactones produced by Streptomyces avermitilis isolated from a soil in Japan
    • Umezawa H, Demain AL, Hata R, Hutchinson CR (eds, Tokyo
    • Stapley EO (1982) Avermectins, antiparasitic lactones produced by Streptomyces avermitilis isolated from a soil in Japan. In: Umezawa H, Demain AL, Hata R, Hutchinson CR (eds) Trends in antibiotic research. Japan Antibiotic Research Association, Tokyo, pp 154-170
    • (1982) Trends in antibiotic research. Japan Antibiotic Research Association , pp. 154-170
    • Stapley, E.O.1
  • 188
    • 0034210940 scopus 로고    scopus 로고
    • Effect of a global regulatory gene, afsR2 from Streptomyces lividans on avermectin production in Streptomyces avermitilis
    • Lee J-Y, Hwang Y-S, Kim S-S, Kim E-S, Choi C-Y (2000) Effect of a global regulatory gene, afsR2 from Streptomyces lividans on avermectin production in Streptomyces avermitilis . Biosci Bioeng 89:606-608
    • (2000) Biosci. Bioeng , vol.89 , pp. 606-608
    • Lee, J.-Y.1    Hwang, Y.-S.2    Kim, S.-S.3    Kim, E.-S.4    Choi, C.-Y.5
  • 189
    • 0027410919 scopus 로고
    • Transposon mutagenesis by Tn4560 and applications with avermectinproducing Streptomyces avermitilis
    • Ikeda H, Takada Y, Pang C-H, Tanaka H, Omura S (1993) Transposon mutagenesis by Tn4560 and applications with avermectinproducing Streptomyces avermitilis . J Bacteriol 175:2077-2082
    • (1993) J. Bacteriol. , vol.175 , pp. 2077-2082
    • Ikeda, H.1    Takada, Y.2    Pang, C.-H.3    Tanaka, H.4    Omura, S.5
  • 191
    • 33749177715 scopus 로고    scopus 로고
    • Construction of ivermectin producer by domain swaps of avermectin polyketide synthase in Streptomyces avermitilis
    • Zhang X, Chen Z, Li M, Wen Y, Song Y, Li J (2006) Construction of ivermectin producer by domain swaps of avermectin polyketide synthase in Streptomyces avermitilis . Appl Microbiol Biotechnol 72:986-994
    • (2006) Appl. Microbiol. Biotechnol. , vol.72 , pp. 986-994
    • Zhang, X.1    Chen, Z.2    Li, M.3    Wen, Y.4    Song, Y.5    Li, J.6
  • 192
    • 0002973568 scopus 로고    scopus 로고
    • The novel avermectin, Doramectin - A successful application of mutasynthesis
    • Hutchinson CR, McAlpine J (eds. Society for Industrial Microbiology, Fairfax
    • McArthur HIA (1998) The novel avermectin, Doramectin-a successful application of mutasynthesis. In: Hutchinson CR, McAlpine J (eds) Developments in industrial microbiology-BMP 97. Society for Industrial Microbiology, Fairfax, pp 43-48
    • (1998) Developments in Industrial Microbiology-BMP 97 , pp. 43-48
    • McArthur, H.I.A.1
  • 193
    • 0016724057 scopus 로고
    • Rapamycin (AY 22 989), a new antifungal antibiotic I Taxonomy of the producing streptomycete and isolation of the active principle
    • Vezina C, Kudelski A, Sehgal SN (1975) Rapamycin (AY 22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot 28:721-726
    • (1975) J. Antibiot. , vol.28 , pp. 721-726
    • Vezina, C.1    Kudelski, A.2    Sehgal, S.N.3
  • 194
    • 0023245677 scopus 로고
    • FK-506, a novel immunosuppressant isolated from Streptomyces I Fermentation, isolation and physico-chemical and biological characteristics
    • Kino T, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M, Kohsaka M, Aoki H, Imanaka H (1987) FK-506, a novel immunosuppressant isolated from Streptomyces . I. Fermentation, isolation and physico-chemical and biological characteristics. J Antibiot 40:1249-1255
    • (1987) J. Antibiot. , vol.40 , pp. 1249-1255
    • Kino, T.1    Hatanaka, H.2    Hashimoto, M.3    Nishiyama, M.4    Goto, T.5    Okuhara, M.6    Kohsaka, M.7    Aoki, H.8    Imanaka, H.9
  • 195
    • 71249150385 scopus 로고    scopus 로고
    • Strain development of Streptomyces sp. for tacrolimus production using sequential adaptation
    • Jung S, Moon S, Lee K, Park Y-J, Yoon S et al (2009) Strain development of Streptomyces sp. for tacrolimus production using sequential adaptation. J Ind Microbiol Biotechnol 36:1467-1471
    • (2009) J. Ind. Microbiol. Biotechnol. , vol.36 , pp. 1467-1471
    • Jung, S.1    Moon, S.2    Lee, K.3    Park, Y.-J.4    Yoon, S.5
  • 196
    • 67349098201 scopus 로고    scopus 로고
    • Generation of high-yield rapamycin-producing strains through protoplast-related techniques
    • Chen X, Wei P, Fan L, Yang D, Zhu X, Shen W et al (2009) Generation of high-yield rapamycin-producing strains through protoplast-related techniques. Appl Microbiol Biotechnol 83:507-512
    • (2009) Appl. Microbiol. Biotechnol. , vol.83 , pp. 507-512
    • Chen, X.1    Wei, P.2    Fan, L.3    Yang, D.4    Zhu, X.5    Shen, W.6
  • 197
    • 34347388220 scopus 로고    scopus 로고
    • Roles of rapH and rapG in positive regulation of rapamycin biosynthesis in Streptomyces hygroscopicus
    • Kuscer E, Coates N, Challis I, Gregory M, Wilkinson B, Sheridan R, Petkovic H (2007) Roles of rapH and rapG in positive regulation of rapamycin biosynthesis in Streptomyces hygroscopicus . J Bacteriol 189:4756-4763
    • (2007) J. Bacteriol. , vol.189 , pp. 4756-4763
    • Kuscer, E.1    Coates, N.2    Challis, I.3    Gregory, M.4    Wilkinson, B.5    Sheridan, R.6    Petkovic, H.7
  • 198
    • 70349937056 scopus 로고    scopus 로고
    • Enhanced production of spinosad in Saccharopolyspora spinosa by genome shuf fl ing
    • Jin ZH, Xu B, Lin SZ, Jin QC, Cen PL (2009) Enhanced production of spinosad in Saccharopolyspora spinosa by genome shuf fl ing. Appl Biochem Biotechnol 159:655-663
    • (2009) Appl. Biochem. Biotechnol. , vol.159 , pp. 655-663
    • Jin, Z.H.1    Xu, B.2    Lin, S.Z.3    Jin, Q.C.4    Cen, P.L.5
  • 199
    • 37749004225 scopus 로고    scopus 로고
    • Protein therapeutics: A summary and pharmacological classi fi cation
    • Leader B, Baca QJ, Golan De (2008) Protein therapeutics: A summary and pharmacological classi fi cation. Nat Rev Drug Discov 7:21-39
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 21-39
    • Leader, B.1    Baca, Q.J.2    Golan, D.E.3
  • 200
    • 61349178501 scopus 로고    scopus 로고
    • Production of recombinant proteins by microbes and higher organisms
    • Demain AL, Vaishnav P (2009) Production of recombinant proteins by microbes and higher organisms. Biotechnol Adv 27:297-306
    • (2009) Biotechnol. Adv. , vol.27 , pp. 297-306
    • Demain, A.L.1    Vaishnav, P.2
  • 201
    • 61349165045 scopus 로고    scopus 로고
    • Expression systems for process and product improvement
    • Rayder RA (2008) Expression systems for process and product improvement. Bioprocess Int 6:4-9
    • (2008) Bioprocess Int. , vol.6 , pp. 4-9
    • Rayder, R.A.1
  • 202
  • 204
    • 33747666218 scopus 로고    scopus 로고
    • Overview of bacterial expression systems for heterologous protein production: From molecular and biochemical fundamentals to commercial systems
    • Terpe K (1996) Overview of bacterial expression systems for heterologous protein production: From molecular and biochemical fundamentals to commercial systems. Appl Microbiol Biotechnol 72:211-223
    • (1996) Appl. Microbiol. Biotechnol. , vol.72 , pp. 211-223
    • Terpe, K.1
  • 205
    • 0000516479 scopus 로고    scopus 로고
    • Escherichia coli recombinant DNA technology
    • Neidhardt FC (ed, 2nd edn. American Society of Microbiology, Washington DC
    • Swartz J (1996) Escherichia coli recombinant DNA technology. In: Neidhardt FC (ed) Esherichia coli and Salmonella: Cellular and molecular biology, 2nd edn. American Society of Microbiology, Washington, DC, pp 1693-1771
    • (1996) Esherichia Coli and Salmonella: Cellular and Molecular Biology , pp. 1693-1771
    • Swartz, J.1
  • 206
    • 39849097985 scopus 로고    scopus 로고
    • Reduction of acetate accumulation in Escherichia coli cultures for increased recombinant protein production
    • Wong MS, Wu S, Causey TB, Bennett GN, San K-Y (2008) Reduction of acetate accumulation in Escherichia coli cultures for increased recombinant protein production. Metab Eng 10:97-108
    • (2008) Metab. Eng. , vol.10 , pp. 97-108
    • Wong, M.S.1    Wu, S.2    Causey, T.B.3    Bennett, G.N.4    San, K.-Y.5
  • 207
    • 62549137028 scopus 로고    scopus 로고
    • Grappling with biologic manufacturing concerns
    • Morrow K.J.
    • Morrow KJ (2009) Grappling with biologic manufacturing concerns. Genet Eng Biotechnol News 29(5):54-55
    • (2009) Genet. Eng. Biotechnol. News , vol.29 , Issue.5 , pp. 54-55
  • 208
    • 0043031143 scopus 로고    scopus 로고
    • Enhanced production of insulin-like growth factor I fusion protein in Escherichia coli by coexpression of the down-regulated genes identi fi ed by transcriptome profiling
    • Choi JH, Lee SJ, Lee SJ, Lee SY (2003) Enhanced production of insulin-like growth factor I fusion protein in Escherichia coli by coexpression of the down-regulated genes identi fi ed by transcriptome profiling. Appl Environ Microbiol 69:4737-4742
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 4737-4742
    • Choi, J.H.1    Lee, S.J.2    Lee, S.J.3    Lee, S.Y.4
  • 209
    • 8844262654 scopus 로고    scopus 로고
    • High level recombinant protein expression in Ralstonia eutropha using T7 RNA polymerase based amplification
    • Barnard GC, Henderson GE, Srinivasan S, Gerngross TU (2004) High level recombinant protein expression in Ralstonia eutropha using T7 RNA polymerase based amplification. Protein Expr Purif 38:264-271
    • (2004) Protein Expr. Purif. , vol.38 , pp. 264-271
    • Barnard, G.C.1    Henderson, G.E.2    Srinivasan, S.3    Gerngross, T.U.4
  • 210
    • 61349153751 scopus 로고    scopus 로고
    • Vendor voice: A new paradigm for bacterial strain engineering
    • Squires CH, Lucy P (2008) Vendor voice: A new paradigm for bacterial strain engineering. Bioprocess Int 6:22-27
    • (2008) Bioprocess Int. , vol.6 , pp. 22-27
    • Squires, C.H.1    Lucy, P.2
  • 211
    • 0024505731 scopus 로고
    • High level expression, purification, and characterization of recombinant human tumor necrosis factor synthesized in the methylotrophic yeast Pichia pastoris
    • Sreekrishana K, Nelles L, Potenz R, Cruze J, Mazzaferro P et al (1989) High level expression, purification, and characterization of recombinant human tumor necrosis factor synthesized in the methylotrophic yeast Pichia pastoris . Biochemistry 28:4117-4125
    • (1989) Biochemistry , vol.28 , pp. 4117-4125
    • Sreekrishana, K.1    Nelles, L.2    Potenz, R.3    Cruze, J.4    Mazzaferro, P.5
  • 213
    • 14744271884 scopus 로고
    • High level expression of tetanus toxin fragment C in Pichia pastoris strains containing multiple tandem integrations of the gene
    • Clare JJ, Rayment FB, Ballantine SP, Sreekrishna K, Romanos MA (1991) High level expression of tetanus toxin fragment C in Pichia pastoris strains containing multiple tandem integrations of the gene. Nat Biotechnol 9:455-460
    • (1991) Nat. Biotechnol. , vol.9 , pp. 455-460
    • Clare, J.J.1    Rayment, F.B.2    Ballantine, S.P.3    Sreekrishna, K.4    Romanos, M.A.5
  • 215
    • 54049146656 scopus 로고    scopus 로고
    • Strategic protein production
    • Morrow K.J.
    • Morrow KJ (2007) Strategic protein production. Genet Eng Biotechnol News 27:50-54
    • (2007) Genet. Eng. Biotechnol. News , vol.27 , pp. 50-54
  • 217
    • 38349002470 scopus 로고    scopus 로고
    • Genetic engineering of Filamentous fubgi-progress, obstacles and future trends
    • Meyer V (2008) Genetic engineering of Filamentous fubgi-progress, obstacles and future trends. Biotechnol Adv 26:177-185
    • (2008) Biotechnol. Adv. , vol.26 , pp. 177-185
    • Meyer, V.1
  • 218
    • 57249097123 scopus 로고    scopus 로고
    • Developing Aspergillus as a host for heterologous expression
    • Lubertozzi D, Keasling JD (2009) Developing Aspergillus as a host for heterologous expression. Biotechnol Adv 27:53-75
    • (2009) Biotechnol. Adv. , vol.27 , pp. 53-75
    • Lubertozzi, D.1    Keasling, J.D.2
  • 222
    • 84864146423 scopus 로고
    • Human lactoferrin from Aspergillus spp
    • Headon DR, Wyatt RD (1995) Human lactoferrin from Aspergillus spp. SIM News 45:113-117
    • (1995) SIM News , vol.45 , pp. 113-117
    • Headon, D.R.1    Wyatt, R.D.2
  • 224
    • 0036535753 scopus 로고    scopus 로고
    • Recombinant protein expression for therapeutic applications
    • Andersen DC, Krummen L (2002) Recombinant protein expression for therapeutic applications. Curr Opin Biotechnol 13:117-123
    • (2002) Curr. Opin. Biotechnol. , vol.13 , pp. 117-123
    • Andersen, D.C.1    Krummen, L.2
  • 225
    • 61349176665 scopus 로고    scopus 로고
    • Animal cell culture; novel systems for research and production
    • Wrotnowski C (1998) Animal cell culture; novel systems for research and production. Genet Eng News 18(3):13-37
    • (1998) Genet. Eng. News , vol.18 , Issue.3 , pp. 13-37
    • Wrotnowski, C.1
  • 226
    • 35548983052 scopus 로고    scopus 로고
    • Advancing mammalian cell culture engineering using genome-scale technologies
    • Grif fi n TJ, Seth G, Xie H, Bandhakavi S, Hu W-S (2007) Advancing mammalian cell culture engineering using genome-scale technologies. Trends Biotechnol 25:401-408
    • (2007) Trends Biotechnol. , vol.25 , pp. 401-408
    • Griffin, T.J.1    Seth, G.2    Xie, H.3    Bandhakavi, S.4    Hu, W.-S.5
  • 227
    • 77953469156 scopus 로고    scopus 로고
    • Many considerations in selecting bioproduction culture media
    • Decaria P, Smith A, Whitford W (2009) Many considerations in selecting bioproduction culture media. Bioprocess Int 7:44-51
    • (2009) Bioprocess Int. , vol.7 , pp. 44-51
    • Decaria, P.1    Smith, A.2    Whitford, W.3
  • 228
    • 77957589343 scopus 로고    scopus 로고
    • Genetic engineering leads to microbial, animal cell, and transgenic expression systems
    • Scott C, Montgomery SA, Rosin LJ (2007) Genetic engineering leads to microbial, animal cell, and transgenic expression systems. BIO Internat Convention, pp. 27-34
    • (2007) BIO Internat Convention , pp. 27-34
    • Scott, C.1    Montgomery, S.A.2    Rosin, L.J.3
  • 229
    • 37349024048 scopus 로고    scopus 로고
    • Improving protein production processes
    • Morrow K.J.
    • Morrow KJ (2007) Improving protein production processes. Genet Eng Biotechnol News 27:44-47
    • (2007) Genet. Eng. Biotechnol. News , vol.27 , pp. 44-47
  • 230
    • 85012852409 scopus 로고    scopus 로고
    • Antibody production using mammalian cell culture-how high can we push productivity ? SIM annual meeting program & abstract
    • Ryll T (2008) Antibody production using mammalian cell culture-how high can we push productivity ? SIM Annual Meeting Program & Abstract, San Diego, S146, p.101
    • (2008) San Diego S146 , pp. 101
    • Ryll, T.1
  • 232
    • 61349131530 scopus 로고    scopus 로고
    • A review of therapeutic protein expression by mammalian cells
    • CocoMartin JM, Harmsen MM (2008) A review of therapeutic protein expression by mammalian cells. Bioprocess Int 6:28-33
    • (2008) Bioprocess Int. , vol.6 , pp. 28-33
    • CocoMartin, J.M.1    Harmsen, M.M.2
  • 233
    • 43249118744 scopus 로고    scopus 로고
    • A technology bet DSM's pharma product unit leverages its biotech strength to survive in a tough environment
    • Jarvis LM (2008) A technology bet. DSM's pharma product unit leverages its biotech strength to survive in a tough environment. Chem Eng News 86:30-31
    • (2008) Chem. Eng. News , vol.86 , pp. 30-31
    • Jarvis, L.M.1
  • 234
    • 0025792409 scopus 로고
    • Production scale insect cell culture
    • Agathos SN (1991) Production scale insect cell culture. Biotechnol Adv 9:51-68
    • (1991) Biotechnol. Adv. , vol.9 , pp. 51-68
    • Agathos, S.N.1
  • 235
    • 0023881356 scopus 로고
    • Trends in the development of baculovirus expression vectors
    • Luckow VA, Summers MD (1988) Trends in the development of baculovirus expression vectors. Nat Biotechnol 6:47-55
    • (1988) Nat. Biotechnol. , vol.6 , pp. 47-55
    • Luckow, V.A.1    Summers, M.D.2
  • 236
    • 0024152865 scopus 로고
    • Baculoviruses as gene expression vectors
    • Miller LK (1988) Baculoviruses as gene expression vectors. Annu Rev Microbiol 42:177-199
    • (1988) Annu. Rev. Microbiol. , vol.42 , pp. 177-199
    • Miller, L.K.1
  • 237
    • 61349150719 scopus 로고    scopus 로고
    • Baculovirus expression system: The production of proteins for diagnostic, human therapeutic or vaccine use
    • Nov)rfis1
    • Wilkinson BE, Cox M (1998) Baculovirus expression system: The production of proteins for diagnostic, human therapeutic or vaccine use. Genet Eng News 18, 35(Nov)
    • (1998) Genet. Eng. News , vol.18 , pp. 35
    • Wilkinson, B.E.1    Cox, M.2
  • 238
    • 0024242299 scopus 로고
    • Large scale insect cell culture for recombinant protein production
    • Maiorella B, Harano D (1988) Large scale insect cell culture for recombinant protein production. Nat Biotechnol 6:1406-1409
    • (1988) Nat. Biotechnol. , vol.6 , pp. 1406-1409
    • Maiorella, B.1    Harano, D.2
  • 239
    • 37349024048 scopus 로고    scopus 로고
    • Improving protein production processes
    • Morrow KJ Jr (2007) Improving protein production processes. Genet Eng News 27(5):50-54
    • (2007) Genet. Eng. News , vol.27 , Issue.5 , pp. 50-54
    • Morrow Jr., K.J.1
  • 240
    • 61349160645 scopus 로고
    • Baculovirus vectors for making proteins in insect cells
    • Knight P (1991) Baculovirus vectors for making proteins in insect cells. ASM News 57:567-570
    • (1991) ASM News , vol.57 , pp. 567-570
    • Knight, P.1
  • 241
    • 0026371479 scopus 로고
    • Industrial enzymes-developments in production and application
    • Falch E (1991) Industrial enzymes-developments in production and application. Biotechnol Adv 9:643-658
    • (1991) Biotechnol. Adv. , vol.9 , pp. 643-658
    • Falch, E.1
  • 242
    • 0000434975 scopus 로고    scopus 로고
    • Industrial enzyme technology
    • Cowan D (1996) Industrial enzyme technology. Trends Biotechnol 14:177-178
    • (1996) Trends Biotechnol. , vol.14 , pp. 177-178
    • Cowan, D.1
  • 243
    • 0037247952 scopus 로고    scopus 로고
    • Phytases: Microbial sources, production, purification, and potential biotechnological applications
    • Vohra A, Satyanarayana T (2003) Phytases: Microbial sources, production, purification, and potential biotechnological applications. Crit Rev Biotechnol 23:29-60
    • (2003) Crit. Rev. Biotechnol. , vol.23 , pp. 29-60
    • Vohra, A.1    Satyanarayana, T.2
  • 244
    • 84974560892 scopus 로고    scopus 로고
    • Industrial biotechnology overview
    • Schaechter M, Lederberg J (eds, 3rd edn Elsevier, Oxford
    • Vaishnav P, Demain AL (2009) Industrial biotechnology overview. In: Schaechter M, Lederberg J (eds) Encyclopedia of microbiology, 3rd edn. Elsevier, Oxford, p 335
    • (2009) Encyclopedia of Microbiology , pp. 335
    • Vaishnav, P.1    Demain, A.L.2
  • 245
    • 0031132511 scopus 로고    scopus 로고
    • Bacterial biocatalysis: Stealing a page from nature's book
    • Wackett LP (1997) Bacterial biocatalysis: Stealing a page from nature's book. Nat Biotechnol 15:415-416
    • (1997) Nat. Biotechnol. , vol.15 , pp. 415-416
    • Wackett, L.P.1
  • 246
    • 0020438726 scopus 로고
    • Molecular cloning ofα-amylase gene from Bacillus amyloliquefaciens and its expression in Bacillus subtilis
    • Palva I (1982) Molecular cloning ofα-amylase gene from Bacillus amyloliquefaciens and its expression in Bacillus subtilis . Gene 19: 81-87
    • (1982) Gene. , vol.19 , pp. 81-87
    • Palva, I.1
  • 247
    • 0022444645 scopus 로고
    • Overproduction from a cellulase gene with a high guanosine-plus-cytosine content in Escherichia coli
    • O'Neill GP, Kilburn DG, Warren RAJ, Miller RC (1986) Overproduction from a cellulase gene with a high guanosine-plus-cytosine content in Escherichia coli . Appl Environ Microbiol 52:737-743
    • (1986) Appl. Environ. Microbiol. , vol.52 , pp. 737-743
    • O'Neill, G.P.1    Kilburn, D.G.2    Warren, R.A.J.3    Miller, R.C.4
  • 249
    • 84936285575 scopus 로고
    • Fungi: The perfect hosts
    • Van Brunt J (1986) Fungi: The perfect hosts? Biotechnology 4:1057-1062
    • (1986) Biotechnology , vol.4 , pp. 1057-1062
    • Van Brunt, J.1
  • 250
    • 0022885127 scopus 로고
    • Cloning of the xylanase gene of Streptomyces lividans
    • Mondou F, Shareck F, Morosoli R, Kleupfel D (1986) Cloning of the xylanase gene of Streptomyces lividans . Gene 49:323-329
    • (1986) Gene. , vol.49 , pp. 323-329
    • Mondou, F.1    Shareck, F.2    Morosoli, R.3    Kleupfel, D.4
  • 253
    • 0033976143 scopus 로고    scopus 로고
    • Directed evolution of enantioselective enzymes for organic chemistry
    • Jaeger KE, Reetz MT (2000) Directed evolution of enantioselective enzymes for organic chemistry. Curr Opin Chem Biol 4:68-73
    • (2000) Curr. Opin. Chem. Biol. , vol.4 , pp. 68-73
    • Jaeger, K.E.1    Reetz, M.T.2
  • 254
    • 0034878844 scopus 로고    scopus 로고
    • Directed evolution of biphenyl dioxygenase: Emergence of enhanced degradation capacity for benzene, toluene, and alkylbenzenes
    • Suenaga H, Mitsokua M, Ura Y, Watanabe T, Furukawa K (2001) Directed evolution of biphenyl dioxygenase: Emergence of enhanced degradation capacity for benzene, toluene, and alkylbenzenes. J Bacteriol 183: 5441-5444
    • (2001) J. Bacteriol. , vol.183 , pp. 5441-5444
    • Suenaga, H.1    Mitsokua, M.2    Ura, Y.3    Watanabe, T.4    Furukawa, K.5
  • 255
    • 0035844691 scopus 로고    scopus 로고
    • Enhancement of stability and activity of phospholipase A(1) in organic solvents by directed evolution
    • Song JK, Rhee JS (2001) Enhancement of stability and activity of phospholipase A(1) in organic solvents by directed evolution. Biochim Biophys Acta 1547:370-378
    • (2001) Biochim Biophys Acta , vol.1547 , pp. 370-378
    • Song, J.K.1    Rhee, J.S.2
  • 256
    • 0034833072 scopus 로고    scopus 로고
    • Novel enzyme activities and functional plasticity revealed by recombining highly homologous enzymes
    • Raillard S, Krebber A, Chen Y, Ness JE, Bermudez E, Trinidad R et al (2001) Novel enzyme activities and functional plasticity revealed by recombining highly homologous enzymes. Chem Biol 8:891-898
    • (2001) Chem. Biol. , vol.8 , pp. 891-898
    • Raillard, S.1    Krebber, A.2    Chen, Y.3    Ness, J.E.4    Bermudez, E.5    Trinidad, R.6
  • 258
    • 0036845827 scopus 로고    scopus 로고
    • DNA shuf fl ing: Induced molecular breeding to produce new generation long-lasting vaccines
    • Marshall SH (2002) DNA shuf fl ing: Induced molecular breeding to produce new generation long-lasting vaccines. Biotechnol Adv 20:229-238
    • (2002) Biotechnol. Adv. , vol.20 , pp. 229-238
    • Marshall, S.H.1
  • 260
  • 261
    • 0029670330 scopus 로고    scopus 로고
    • Improved green fluorescent protein by molecular evolution using DNA shuf fl ing
    • Crameri A, Whitehorn A, Stemmer WPC (1996) Improved green fluorescent protein by molecular evolution using DNA shuf fl ing. Nat Biotechnol 14:315-319
    • (1996) Nat. Biotechnol. , vol.14 , pp. 315-319
    • Crameri, A.1    Whitehorn, A.2    Stemmer, W.P.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.