Generation of high-yield rapamycin-producing strains through protoplasts-related techniques

Applied Microbiology and Biotechnology

Volumn 83, Issue 3, 2009, Pages 507-512

  Chen, Xiyang ^a   Wei, Peilian ^b   Fan, Limei ^c   Yang, Dong ^a   Zhu, Xiangchen ^a   Shen, Wenhe ^a   Xu, Zhinan ^a   Cen, Peilin ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c ZHEJIANG UNIVERSITY CITY COLLEGE   (China)

Author keywords

Genome shuffling; Protoplast fusion; Rapamycin; Streptomyces hygroscopicus

Indexed keywords

CLINICAL MEDICINE; GENE SEQUENCES; GENOME SHUFFLING; MACROLIDE; NATURAL PRODUCTS; PARENTAL STRAINS; PROTOPLAST FUSION; RAPAMYCIN; STREPTOMYCES HYGROSCOPICUS; SYSTEMATIC RESEARCH; TARGET GENES; YIELD STRAIN;

GENES;

STRAIN;

RAPAMYCIN;

BACTERIUM; GENOME;

ARTICLE; BACTERIAL MUTATION; BACTERIAL STRAIN; CONTROLLED STUDY; GENE CLUSTER; GENE SEQUENCE; NONHUMAN; PROTOPLAST; STREPTOMYCES; STREPTOMYCES ERYTHREUS; STREPTOMYCES HYGROSCOPICUS;

DNA SHUFFLING; GENETIC TECHNIQUES; MUTATION; PROTOPLASTS; SIROLIMUS; STREPTOMYCES;

SACCHAROPOLYSPORA ERYTHRAEA; STREPTOMYCES HYGROSCOPICUS;

EID: 67349098201     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-1918-7     Document Type: Article

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