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Journal of the American Chemical Society

Volumn 124, Issue 21, 2002, Pages 6056-6062

Rationally designed glycosylated premithramycins: Hybrid aromatic polyketides using genes from three different biosynthetic pathways

(11) Trefzer, Axel b Blanco, Gloria c Remsing, Lily a Künzel, Eva a Rix, Uwe a Lipata, Fredilyn a Braña, Alfredo F c Méndez, Carmen c Rohr, Jürgen a Bechthold, Andreas b Salas, José A c

a MEDICAL UNIVERSITY OF SOUTH CAROLINA (United States)

b UNIVERSITY OF FREIBURG (Germany)

c DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACCEPTOR SUBSTRATES;

BIOCHEMICAL ENGINEERING; BIOSYNTHESIS; POLYMERS; SUGARS;

GENES;

9 C DIOLIVOSYLPREMITHRAMYCINONE; 9 C MYCAROSYL 4 O DEMETHYLPREMITHRAMYCINONE; 9 C MYCAROSYLPREMITHRAMYCINONE; 9 C OLIVOSYL 4 O DEMETHYLPREMITHRAMYCINONE; 9 C OLIVOSYLPREMITHRAMYCINONE; ANTINEOPLASTIC AGENT; MITHRAMYCIN; POLYKETIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COMBINATORIAL CHEMISTRY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STREPTOMYCES FRADIAE; STRUCTURE ANALYSIS;

ANTIBIOTICS, ANTINEOPLASTIC; GLYCOSIDES; GLYCOSYLTRANSFERASES; PLICAMYCIN; STREPTOMYCES;

EID: 0037140766 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja017385l Document Type: Article

Times cited : (72)

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