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Volumn 25, Issue 9, 2007, Pages 401-408

Advancing mammalian cell culture engineering using genome-scale technologies

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; COST EFFECTIVENESS; GENES; MAMMALS; PROTEINS;

EID: 35548983052     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibtech.2007.07.004     Document Type: Review
Times cited : (53)

References (73)
  • 1
    • 33749256407 scopus 로고    scopus 로고
    • Engineering cells for cell culture bioprocessing-physiological fundamentals
    • Seth G., et al. Engineering cells for cell culture bioprocessing-physiological fundamentals. Adv. Biochem. Eng. Biotechnol. 101 (2006) 119-164
    • (2006) Adv. Biochem. Eng. Biotechnol. , vol.101 , pp. 119-164
    • Seth, G.1
  • 2
    • 8344271026 scopus 로고    scopus 로고
    • Production of recombinant protein therapeutics in cultivated mammalian cells
    • Wurm F.M. Production of recombinant protein therapeutics in cultivated mammalian cells. Nat. Biotechnol. 22 (2004) 1393-1398
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1393-1398
    • Wurm, F.M.1
  • 3
    • 1642325279 scopus 로고    scopus 로고
    • Life and death in mammalian cell culture: strategies for apoptosis inhibition
    • Arden N., and Betenbaugh M.J. Life and death in mammalian cell culture: strategies for apoptosis inhibition. Trends Biotechnol. 22 (2004) 174-180
    • (2004) Trends Biotechnol. , vol.22 , pp. 174-180
    • Arden, N.1    Betenbaugh, M.J.2
  • 4
    • 25444435396 scopus 로고    scopus 로고
    • Glycoengineering: the effect of glycosylation on the properties of therapeutic proteins
    • Sinclair A.M., and Elliott S. Glycoengineering: the effect of glycosylation on the properties of therapeutic proteins. J. Pharm. Sci. 94 (2005) 1626-1635
    • (2005) J. Pharm. Sci. , vol.94 , pp. 1626-1635
    • Sinclair, A.M.1    Elliott, S.2
  • 5
    • 0035930949 scopus 로고    scopus 로고
    • Blocking of acidosis-mediated apoptosis by a reduction of lactate dehydrogenase activity through antisense mRNA expression
    • Jeong D., et al. Blocking of acidosis-mediated apoptosis by a reduction of lactate dehydrogenase activity through antisense mRNA expression. Biochem. Biophys. Res. Commun. 289 (2001) 1141-1149
    • (2001) Biochem. Biophys. Res. Commun. , vol.289 , pp. 1141-1149
    • Jeong, D.1
  • 6
    • 0035808169 scopus 로고    scopus 로고
    • Engineering of a mammalian cell line for reduction of lactate formation and high monoclonal antibody production
    • Chen K., et al. Engineering of a mammalian cell line for reduction of lactate formation and high monoclonal antibody production. Biotechnol. Bioeng. 72 (2001) 55-61
    • (2001) Biotechnol. Bioeng. , vol.72 , pp. 55-61
    • Chen, K.1
  • 7
    • 0033385223 scopus 로고    scopus 로고
    • Improvement of the primary metabolism of cell cultures by introducing a new cytoplasmic pyruvate carboxylase reaction
    • Irani N., et al. Improvement of the primary metabolism of cell cultures by introducing a new cytoplasmic pyruvate carboxylase reaction. Biotechnol. Bioeng. 66 (1999) 238-246
    • (1999) Biotechnol. Bioeng. , vol.66 , pp. 238-246
    • Irani, N.1
  • 8
    • 13544249755 scopus 로고    scopus 로고
    • Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line
    • Borth N., et al. Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line. Biotechnol. Prog. 21 (2005) 106-111
    • (2005) Biotechnol. Prog. , vol.21 , pp. 106-111
    • Borth, N.1
  • 9
    • 0029360697 scopus 로고
    • Alteration of hybridoma viability and antibody secretion in transfectomas with inducible overexpression of protein disulfide isomerase
    • Kitchin K., and Flickinger M.C. Alteration of hybridoma viability and antibody secretion in transfectomas with inducible overexpression of protein disulfide isomerase. Biotechnol. Prog. 11 (1995) 565-574
    • (1995) Biotechnol. Prog. , vol.11 , pp. 565-574
    • Kitchin, K.1    Flickinger, M.C.2
  • 10
    • 0034281801 scopus 로고    scopus 로고
    • Effect of PDI overexpression on recombinant protein secretion in CHO cells
    • Davis R., et al. Effect of PDI overexpression on recombinant protein secretion in CHO cells. Biotechnol. Prog. 16 (2000) 736-743
    • (2000) Biotechnol. Prog. , vol.16 , pp. 736-743
    • Davis, R.1
  • 11
    • 33646078130 scopus 로고    scopus 로고
    • Xbp1-based engineering of secretory capacity enhances the productivity of Chinese hamster ovary cells
    • Tigges M., and Fussenegger M. Xbp1-based engineering of secretory capacity enhances the productivity of Chinese hamster ovary cells. Metab. Eng. 8 (2006) 264-272
    • (2006) Metab. Eng. , vol.8 , pp. 264-272
    • Tigges, M.1    Fussenegger, M.2
  • 12
    • 0031945008 scopus 로고    scopus 로고
    • Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells
    • Fussenegger M., et al. Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells. Nat. Biotechnol. 16 (1998) 468-472
    • (1998) Nat. Biotechnol. , vol.16 , pp. 468-472
    • Fussenegger, M.1
  • 13
    • 0037021802 scopus 로고    scopus 로고
    • Regulation of cell cycle and productivity in NS0 cells by the over-expression of p21CIP1
    • Watanabe S., et al. Regulation of cell cycle and productivity in NS0 cells by the over-expression of p21CIP1. Biotechnol. Bioeng. 77 (2002) 1-7
    • (2002) Biotechnol. Bioeng. , vol.77 , pp. 1-7
    • Watanabe, S.1
  • 14
    • 1442344781 scopus 로고    scopus 로고
    • A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures
    • Figueroa Jr. B., et al. A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures. Metab. Eng. 5 (2003) 230-245
    • (2003) Metab. Eng. , vol.5 , pp. 230-245
    • Figueroa Jr., B.1
  • 15
    • 0034607154 scopus 로고    scopus 로고
    • Part II. Overexpression of bcl-2 family members enhances survival of mammalian cells in response to various culture insults
    • Mastrangelo A.J., et al. Part II. Overexpression of bcl-2 family members enhances survival of mammalian cells in response to various culture insults. Biotechnol. Bioeng. 67 (2000) 555-564
    • (2000) Biotechnol. Bioeng. , vol.67 , pp. 555-564
    • Mastrangelo, A.J.1
  • 16
    • 15844397398 scopus 로고    scopus 로고
    • Diminished cell proliferation associated with the death-protective activity of Bcl-2
    • Borner C. Diminished cell proliferation associated with the death-protective activity of Bcl-2. J. Biol. Chem. 271 (1996) 12695-12698
    • (1996) J. Biol. Chem. , vol.271 , pp. 12695-12698
    • Borner, C.1
  • 17
    • 0033587794 scopus 로고    scopus 로고
    • Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells
    • Simpson N.H., et al. Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells. Biotechnol. Bioeng. 64 (1999) 174-186
    • (1999) Biotechnol. Bioeng. , vol.64 , pp. 174-186
    • Simpson, N.H.1
  • 18
    • 1442277071 scopus 로고    scopus 로고
    • Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions
    • Figueroa Jr. B., et al. Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions. Biotechnol. Bioeng. 85 (2004) 589-600
    • (2004) Biotechnol. Bioeng. , vol.85 , pp. 589-600
    • Figueroa Jr., B.1
  • 19
    • 0033526539 scopus 로고    scopus 로고
    • Dose-dependent reduction of apoptosis in nutrient-limited cultures of NS/0 myeloma cells transfected with the E1B-19K adenoviral gene
    • Mercille S., et al. Dose-dependent reduction of apoptosis in nutrient-limited cultures of NS/0 myeloma cells transfected with the E1B-19K adenoviral gene. Biotechnol. Bioeng. 63 (1999) 516-528
    • (1999) Biotechnol. Bioeng. , vol.63 , pp. 516-528
    • Mercille, S.1
  • 20
    • 0037140412 scopus 로고    scopus 로고
    • Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3
    • Kim N.S., and Lee G.M. Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3. Biotechnol. Bioeng. 78 (2002) 217-228
    • (2002) Biotechnol. Bioeng. , vol.78 , pp. 217-228
    • Kim, N.S.1    Lee, G.M.2
  • 21
    • 0347130954 scopus 로고    scopus 로고
    • Blocking caspase-3 activity with a U6 SnRNA promoter-driven ribozyme enhances survivability of CHO cells cultured in low serum medium and production of interferon-beta
    • Lai D., et al. Blocking caspase-3 activity with a U6 SnRNA promoter-driven ribozyme enhances survivability of CHO cells cultured in low serum medium and production of interferon-beta. Biotechnol. Bioeng. 85 (2004) 20-28
    • (2004) Biotechnol. Bioeng. , vol.85 , pp. 20-28
    • Lai, D.1
  • 22
    • 0024321508 scopus 로고
    • Alteration of Terminal Glycosylation Sequences on N-Linked Oligosaccharides of Chinese Hamster Ovary Cells by Expression of β-Galactoside α2,6-Sialyltransferase
    • Lee E.U., et al. Alteration of Terminal Glycosylation Sequences on N-Linked Oligosaccharides of Chinese Hamster Ovary Cells by Expression of β-Galactoside α2,6-Sialyltransferase. J. Biol. Chem. 264 (1989) 13848-13855
    • (1989) J. Biol. Chem. , vol.264 , pp. 13848-13855
    • Lee, E.U.1
  • 23
    • 0031730662 scopus 로고    scopus 로고
    • Stable expression of human alpha-2,6-sialyltransferase in Chinese hamster ovary cells: functional consequences for human erythropoietin expression and bioactivity
    • Zhang X., et al. Stable expression of human alpha-2,6-sialyltransferase in Chinese hamster ovary cells: functional consequences for human erythropoietin expression and bioactivity. Biochim. Biophys. Acta 1425 (1998) 441-452
    • (1998) Biochim. Biophys. Acta , vol.1425 , pp. 441-452
    • Zhang, X.1
  • 24
    • 0032925425 scopus 로고    scopus 로고
    • Construction and characterization of stably transfected BHK-21 cells with human-type sialylation characteristic
    • Schlenke P., et al. Construction and characterization of stably transfected BHK-21 cells with human-type sialylation characteristic. Cytotechnology 30 (1999) 17-25
    • (1999) Cytotechnology , vol.30 , pp. 17-25
    • Schlenke, P.1
  • 25
    • 85112384310 scopus 로고    scopus 로고
    • Rational design of novel erythropoiesis stimulating protein (ARANESP): a supersialyated molecule with increased biological activity
    • Elliott S., et al. Rational design of novel erythropoiesis stimulating protein (ARANESP): a supersialyated molecule with increased biological activity. Blood 96 (2000) 82a
    • (2000) Blood , vol.96
    • Elliott, S.1
  • 26
    • 4644245850 scopus 로고    scopus 로고
    • Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing completely defucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity
    • Yamane-Ohnuki N., et al. Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing completely defucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity. Biotechnol. Bioeng. 87 (2004) 614-622
    • (2004) Biotechnol. Bioeng. , vol.87 , pp. 614-622
    • Yamane-Ohnuki, N.1
  • 27
    • 33845898859 scopus 로고    scopus 로고
    • Microarrays Technologies 2006: an overview
    • Hardiman G. Microarrays Technologies 2006: an overview. Pharmacogenomics 7 (2006) 1153-1158
    • (2006) Pharmacogenomics , vol.7 , pp. 1153-1158
    • Hardiman, G.1
  • 28
    • 0346363685 scopus 로고    scopus 로고
    • Large scale gene expression profiling of metabolic shift of mammalian cells in culture
    • Korke R., et al. Large scale gene expression profiling of metabolic shift of mammalian cells in culture. J. Biotechnol. 107 (2004) 1-17
    • (2004) J. Biotechnol. , vol.107 , pp. 1-17
    • Korke, R.1
  • 29
    • 33645573249 scopus 로고    scopus 로고
    • Initial transcriptome and proteome analyses of low culture temperature-induced expression in CHO cells producing erythropoietin
    • Baik J.Y., et al. Initial transcriptome and proteome analyses of low culture temperature-induced expression in CHO cells producing erythropoietin. Biotechnol. Bioeng. 93 (2006) 361-371
    • (2006) Biotechnol. Bioeng. , vol.93 , pp. 361-371
    • Baik, J.Y.1
  • 30
    • 36349014482 scopus 로고    scopus 로고
    • De Leon Gatti, M., et al. (2006) Comparative Transcriptional Analysis of Mouse Hybridoma and Recombinant Chinese Hamster Ovary Cells Undergoing Butyrate Treatement. J. Biosci. Eng. (in press)
  • 31
    • 30944463410 scopus 로고    scopus 로고
    • Genome-wide analysis of the transcriptional response of murine hybridomas to osmotic shock
    • Shen D., and Sharfstein S.T. Genome-wide analysis of the transcriptional response of murine hybridomas to osmotic shock. Biotechnol. Bioeng. 93 (2006) 132-145
    • (2006) Biotechnol. Bioeng. , vol.93 , pp. 132-145
    • Shen, D.1    Sharfstein, S.T.2
  • 32
    • 19544363960 scopus 로고    scopus 로고
    • Large scale gene expression analysis of cholesterol dependence in NS0 cells
    • Seth G., et al. Large scale gene expression analysis of cholesterol dependence in NS0 cells. Biotechnol. Bioeng. 90 (2005) 552-567
    • (2005) Biotechnol. Bioeng. , vol.90 , pp. 552-567
    • Seth, G.1
  • 33
    • 33644900750 scopus 로고    scopus 로고
    • Reverting cholesterol auxotrophy of NS0 cells by altering epigenetic gene silencing
    • Seth G., et al. Reverting cholesterol auxotrophy of NS0 cells by altering epigenetic gene silencing. Biotechnol. Bioeng. 93 (2006) 820-827
    • (2006) Biotechnol. Bioeng. , vol.93 , pp. 820-827
    • Seth, G.1
  • 34
    • 36349011555 scopus 로고    scopus 로고
    • Wong, N.S.C. et al. Enhancing recombinant glycoprotein sialylation through CMP-sialic acid transporter over expression in Chinese hamster ovary cells. Biotechnol. Bioeng.
  • 35
    • 28844482838 scopus 로고    scopus 로고
    • The mouse genome
    • Guenet J.L. The mouse genome. Genome Res. 15 (2005) 1729-1740
    • (2005) Genome Res. , vol.15 , pp. 1729-1740
    • Guenet, J.L.1
  • 36
    • 36348977702 scopus 로고    scopus 로고
    • Evaluation of a genomics platform for cross-species transcriptome analysis of recombinant CHO cells
    • Ernst W., et al. Evaluation of a genomics platform for cross-species transcriptome analysis of recombinant CHO cells. Biotechnol. J. 1 (2006) 639-650
    • (2006) Biotechnol. J. , vol.1 , pp. 639-650
    • Ernst, W.1
  • 37
    • 29844439097 scopus 로고    scopus 로고
    • Over-expression of hTERT in CHOK1 results in decreased apoptosis and reduced serum dependency
    • Crea F., et al. Over-expression of hTERT in CHOK1 results in decreased apoptosis and reduced serum dependency. J. Biotechnol. 121 (2006) 109-123
    • (2006) J. Biotechnol. , vol.121 , pp. 109-123
    • Crea, F.1
  • 38
    • 0035241690 scopus 로고    scopus 로고
    • Mass spectrometry in proteomics
    • Aebersold R., and Goodlett D.R. Mass spectrometry in proteomics. Chem. Rev. 101 (2001) 269-295
    • (2001) Chem. Rev. , vol.101 , pp. 269-295
    • Aebersold, R.1    Goodlett, D.R.2
  • 39
    • 0037328020 scopus 로고    scopus 로고
    • Identification of cellular changes associated with increased production of human growth hormone in a recombinant Chinese hamster ovary cell line
    • Van Dyk D.D., et al. Identification of cellular changes associated with increased production of human growth hormone in a recombinant Chinese hamster ovary cell line. Proteomics 3 (2003) 147-156
    • (2003) Proteomics , vol.3 , pp. 147-156
    • Van Dyk, D.D.1
  • 40
    • 0348044478 scopus 로고    scopus 로고
    • Proteome analysis of antibody-expressing CHO cells in response to hyperosmotic pressure
    • Lee M.S., et al. Proteome analysis of antibody-expressing CHO cells in response to hyperosmotic pressure. Biotechnol. Prog. 19 (2003) 1734-1741
    • (2003) Biotechnol. Prog. , vol.19 , pp. 1734-1741
    • Lee, M.S.1
  • 41
    • 0037332128 scopus 로고    scopus 로고
    • Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion
    • van Anken E., et al. Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion. Immunity 18 (2003) 243-253
    • (2003) Immunity , vol.18 , pp. 243-253
    • van Anken, E.1
  • 42
    • 0035515020 scopus 로고    scopus 로고
    • Proteomic investigation of metabolic shift in mammalian cell culture
    • Seow T.K., et al. Proteomic investigation of metabolic shift in mammalian cell culture. Biotechnol. Prog. 17 (2001) 1137-1144
    • (2001) Biotechnol. Prog. , vol.17 , pp. 1137-1144
    • Seow, T.K.1
  • 43
    • 34447341435 scopus 로고    scopus 로고
    • Molecular portrait of high productivity in recombinant NS0 cells
    • Seth G., et al. Molecular portrait of high productivity in recombinant NS0 cells. Biotechnol. Bioeng. 97 (2007) 933-951
    • (2007) Biotechnol. Bioeng. , vol.97 , pp. 933-951
    • Seth, G.1
  • 44
    • 8844219682 scopus 로고    scopus 로고
    • Comparative proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate
    • Smales C.M., et al. Comparative proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate. Biotechnol. Bioeng. 88 (2004) 474-488
    • (2004) Biotechnol. Bioeng. , vol.88 , pp. 474-488
    • Smales, C.M.1
  • 45
    • 23644460630 scopus 로고    scopus 로고
    • Tag-based approaches for transcriptome research and genome annotation
    • Harbers M., and Carninci P. Tag-based approaches for transcriptome research and genome annotation. Nat. Methods 2 (2005) 495-502
    • (2005) Nat. Methods , vol.2 , pp. 495-502
    • Harbers, M.1    Carninci, P.2
  • 46
    • 0027943920 scopus 로고
    • Comparative genomic hybridization: an overview
    • Houldsworth J., and Chaganti R.S. Comparative genomic hybridization: an overview. Am. J. Pathol. 145 (1994) 1253-1260
    • (1994) Am. J. Pathol. , vol.145 , pp. 1253-1260
    • Houldsworth, J.1    Chaganti, R.S.2
  • 47
    • 33748567134 scopus 로고    scopus 로고
    • Gel-free mass spectrometry-based high throughput proteomics: tools for studying biological response of proteins and proteomes
    • Roe M.R., and Griffin T.J. Gel-free mass spectrometry-based high throughput proteomics: tools for studying biological response of proteins and proteomes. Proteomics 6 (2006) 4678-4687
    • (2006) Proteomics , vol.6 , pp. 4678-4687
    • Roe, M.R.1    Griffin, T.J.2
  • 48
    • 0037435030 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomics
    • Aebersold R., and Mann M. Mass spectrometry-based proteomics. Nature 422 (2003) 198-207
    • (2003) Nature , vol.422 , pp. 198-207
    • Aebersold, R.1    Mann, M.2
  • 49
    • 0012573999 scopus 로고    scopus 로고
    • Multidimensional peptide separations in proteomics
    • Link A.J. Multidimensional peptide separations in proteomics. Trends Biotechnol. 20 (2002) S8-S13
    • (2002) Trends Biotechnol. , vol.20
    • Link, A.J.1
  • 50
    • 0026507564 scopus 로고
    • Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry
    • Hunt D.F., et al. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science 255 (1992) 1261-1263
    • (1992) Science , vol.255 , pp. 1261-1263
    • Hunt, D.F.1
  • 51
    • 0031568420 scopus 로고    scopus 로고
    • Direct analysis and identification of proteins in mixtures by LC/MS/MS and database searching at the low-femtomole level
    • McCormack A.L., et al. Direct analysis and identification of proteins in mixtures by LC/MS/MS and database searching at the low-femtomole level. Anal. Chem. 69 (1997) 767-776
    • (1997) Anal. Chem. , vol.69 , pp. 767-776
    • McCormack, A.L.1
  • 52
    • 18744398125 scopus 로고    scopus 로고
    • Large-scale database searching using tandem mass spectra: looking up the answer in the back of the book
    • Sadygov R.G., et al. Large-scale database searching using tandem mass spectra: looking up the answer in the back of the book. Nat. Methods 1 (2004) 195-202
    • (2004) Nat. Methods , vol.1 , pp. 195-202
    • Sadygov, R.G.1
  • 53
    • 0034662907 scopus 로고    scopus 로고
    • Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology
    • Gygi S.P., et al. Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 9390-9395
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 9390-9395
    • Gygi, S.P.1
  • 54
    • 0035106351 scopus 로고    scopus 로고
    • Large-scale analysis of the yeast proteome by multidimensional protein identification technology
    • Washburn M.P., et al. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat. Biotechnol. 19 (2001) 242-247
    • (2001) Nat. Biotechnol. , vol.19 , pp. 242-247
    • Washburn, M.P.1
  • 55
    • 23844453654 scopus 로고    scopus 로고
    • Recent advancements in differential proteomics based on stable isotope coding
    • Julka S., and Regnier F.E. Recent advancements in differential proteomics based on stable isotope coding. Brief. Funct. Genomic. Proteomic. 4 (2005) 158-177
    • (2005) Brief. Funct. Genomic. Proteomic. , vol.4 , pp. 158-177
    • Julka, S.1    Regnier, F.E.2
  • 56
    • 0033535961 scopus 로고    scopus 로고
    • Accurate quantitation of protein expression and site-specific phosphorylation
    • Oda Y., et al. Accurate quantitation of protein expression and site-specific phosphorylation. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 6591-6596
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 6591-6596
    • Oda, Y.1
  • 57
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • Ong S.E., et al. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol. Cell. Proteomics 1 (2002) 376-386
    • (2002) Mol. Cell. Proteomics , vol.1 , pp. 376-386
    • Ong, S.E.1
  • 58
    • 0032875697 scopus 로고    scopus 로고
    • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
    • Gygi S.P., et al. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat. Biotechnol. 17 (1999) 994-999
    • (1999) Nat. Biotechnol. , vol.17 , pp. 994-999
    • Gygi, S.P.1
  • 59
    • 19944432197 scopus 로고    scopus 로고
    • Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents
    • Ross P.L., et al. Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol. Cell. Proteomics 3 (2004) 1154-1169
    • (2004) Mol. Cell. Proteomics , vol.3 , pp. 1154-1169
    • Ross, P.L.1
  • 60
    • 27744468403 scopus 로고    scopus 로고
    • Proteomics of organelles and large cellular structures
    • Yates III J.R., et al. Proteomics of organelles and large cellular structures. Nat. Rev. Mol. Cell Biol. 6 (2005) 702-714
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 702-714
    • Yates III, J.R.1
  • 61
    • 0037311421 scopus 로고    scopus 로고
    • Global organellar proteomics
    • Taylor S.W., et al. Global organellar proteomics. Trends Biotechnol. 21 (2003) 82-88
    • (2003) Trends Biotechnol. , vol.21 , pp. 82-88
    • Taylor, S.W.1
  • 62
    • 33646473345 scopus 로고    scopus 로고
    • A mammalian organelle map by protein correlation profiling
    • Foster L.J., et al. A mammalian organelle map by protein correlation profiling. Cell 125 (2006) 187-199
    • (2006) Cell , vol.125 , pp. 187-199
    • Foster, L.J.1
  • 63
    • 19944426486 scopus 로고    scopus 로고
    • Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane
    • Marelli M., et al. Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane. J. Cell Biol. 167 (2004) 1099-1112
    • (2004) J. Cell Biol. , vol.167 , pp. 1099-1112
    • Marelli, M.1
  • 64
    • 11944274520 scopus 로고    scopus 로고
    • Nucleolar proteome dynamics
    • Andersen J.S., et al. Nucleolar proteome dynamics. Nature 433 (2005) 77-83
    • (2005) Nature , vol.433 , pp. 77-83
    • Andersen, J.S.1
  • 65
    • 0242522206 scopus 로고    scopus 로고
    • Regulation of apoptosis by Bcl-2 family proteins
    • Burlacu A. Regulation of apoptosis by Bcl-2 family proteins. J. Cell. Mol. Med. 7 (2003) 249-257
    • (2003) J. Cell. Mol. Med. , vol.7 , pp. 249-257
    • Burlacu, A.1
  • 66
    • 23944453389 scopus 로고    scopus 로고
    • Global phosphoproteome of HT-29 human colon adenocarcinoma cells
    • Kim J.E., et al. Global phosphoproteome of HT-29 human colon adenocarcinoma cells. J. Proteome Res. 4 (2005) 1339-1346
    • (2005) J. Proteome Res. , vol.4 , pp. 1339-1346
    • Kim, J.E.1
  • 67
    • 0037417791 scopus 로고    scopus 로고
    • Quantitation of changes in protein phosphorylation: a simple method based on stable isotope labeling and mass spectrometry
    • Bonenfant D., et al. Quantitation of changes in protein phosphorylation: a simple method based on stable isotope labeling and mass spectrometry. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 880-885
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 880-885
    • Bonenfant, D.1
  • 68
    • 4344574540 scopus 로고    scopus 로고
    • Large-scale characterization of HeLa cell nuclear phosphoproteins
    • Beausoleil S.A., et al. Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 12130-12135
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 12130-12135
    • Beausoleil, S.A.1
  • 69
    • 23144441172 scopus 로고    scopus 로고
    • Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry
    • Tao W.A., et al. Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. Nat. Methods 2 (2005) 591-598
    • (2005) Nat. Methods , vol.2 , pp. 591-598
    • Tao, W.A.1
  • 70
    • 15744387329 scopus 로고    scopus 로고
    • Monitoring glycosylation pattern changes of glycoproteins using multi-lectin affinity chromatography
    • Yang Z., and Hancock W.S. Monitoring glycosylation pattern changes of glycoproteins using multi-lectin affinity chromatography. J. Chromatogr. A. 1070 (2005) 57-64
    • (2005) J. Chromatogr. A. , vol.1070 , pp. 57-64
    • Yang, Z.1    Hancock, W.S.2
  • 71
    • 0038699625 scopus 로고    scopus 로고
    • Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry
    • Zhang H., et al. Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. Nat. Biotechnol. 21 (2003) 660-666
    • (2003) Nat. Biotechnol. , vol.21 , pp. 660-666
    • Zhang, H.1
  • 72
    • 8644240243 scopus 로고    scopus 로고
    • Hydrophilic affinity isolation and MALDI multiple-stage tandem mass spectrometry of glycopeptides for glycoproteomics
    • Wada Y., et al. Hydrophilic affinity isolation and MALDI multiple-stage tandem mass spectrometry of glycopeptides for glycoproteomics. Anal. Chem. 76 (2004) 6560-6565
    • (2004) Anal. Chem. , vol.76 , pp. 6560-6565
    • Wada, Y.1
  • 73
    • 0035937542 scopus 로고    scopus 로고
    • Glycoprotein structure determination by mass spectrometry
    • Dell A., and Morris H.R. Glycoprotein structure determination by mass spectrometry. Science 291 (2001) 2351-2356
    • (2001) Science , vol.291 , pp. 2351-2356
    • Dell, A.1    Morris, H.R.2


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