Modulation of k-Ras signaling by natural products

Current Medicinal Chemistry

Volumn 19, Issue 14, 2012, Pages 2273-2291

  Bharate, S B ^a   Singh, B ^a   Vishwakarma, R A ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Cancer; Farnesyl transferase; Isoprenyl cysteine methyl transferase; K Ras; Natural products

Indexed keywords

3 BENZYL 7 CYANO 2,3,4,5 TETRAHYDRO 1 (1H IMIDAZOL 4 YLMETHYL) 4 (2 THIENYLSULFONYL) 1H 1,4 BENZODIAZEPINE; ALPHA,BETA DEHYDROCURVULARIN; ANTINEOPLASTIC AGENT; FARNESYL TRANS TRANSFERASE; GLIOTOXIN; GRANATICIN; K RAS PROTEIN; KALAFUNGIN; LIMONENE; LONAFARNIB; LUPEOL; MANUMYCIN; METHYLTRANSFERASE; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; NANAOMYCIN A; NANAOMYCIN D; NATURAL PRODUCT; OCHRACEOLIDE A; OCHRACEOLIDE B; PENICILLIC ACID; PERILLIC ACID; PERILLYL ALCOHOL; PHOMOIDRIDE A; PHOMOIDRIDE B; SCH 207278; SCH 58450; TAN 1813; TIPIFARNIB; UCF 67C; UCF 76A; UCF 76B; UNCLASSIFIED DRUG; UNINDEXED DRUG; WS 5995C; ZARAGOZIC ACID A; ZARAGOZIC ACID C;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER THERAPY; CELL CYCLE REGULATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CYTOTOXICITY; ENZYME MODIFICATION; HUMAN; NONHUMAN; PALMITOYLATION; PRENYLATION; PROTEIN DEGRADATION; PROTEIN METHYLATION; SIGNAL TRANSDUCTION;

EID: 84860669101     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712800229050     Document Type: Article

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