On the physiological importance of endoproteolysis of CAAX proteins. Heart-specific Rce1 knockout mice develop a lethal cardiomyopathy

Journal of Biological Chemistry

Volumn 279, Issue 6, 2004, Pages 4729-4736

  Bergo, Martin O ^a   Lieu, Hsiao D ^a   Gavino, Bryant J ^a   Ambroziak, Patricia ^a   Otto, James C ^b   Casey, Patrick J ^b   Walker, Quinn M ^a   Young, Stephen G ^a,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL MEMBRANES; CHEMICAL MODIFICATION; HISTOLOGY; PATHOLOGY; PHYSIOLOGY;

ENDOPROTEOLYSIS;

PROTEINS;

AMINOTRANSFERASE; PROTEIN; PROTEIN CAAX; PROTEIN RCE1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME SPECIFICITY; HEART FUNCTION; KNOCKOUT MOUSE; LETHALITY; LIVER HISTOLOGY; MOUSE; NONHUMAN; PRENYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN MOTIF;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARDIOMYOPATHY, DILATED; DNA, COMPLEMENTARY; ENDOPEPTIDASES; LIVER; MICE; MICE, KNOCKOUT; MYOCARDIUM; PROTEINS;

ANIMALIA;

EID: 1042266632     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310081200     Document Type: Article

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