CP-225,917 and CP-263,114, novel ras farnesylation inhibitors from an unidentified fungus. I. Taxonomy, fermentation, isolation, and biochemical properties

Journal of Antibiotics

Volumn 50, Issue 1, 1997, Pages 1-7

  Dabrah, Thomas T ^a   Harwood Jr , H James ^a   Huang, Liang H ^a   Jankovich, Nancy D ^a   Kaneko, Takushi ^a   Li, Jian Cheng ^a   Lindsey, Saralyn ^a   Moshier, Peter M ^a   Subashi, Timothy A ^a   Therrien, Michelle ^a   Watts, Paul C ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN ENZYME; ENZYME INHIBITOR; PHOMOIDRIDE A; PHOMOIDRIDE B; PROTEIN FARNESYLTRANSFERASE; SQUALENE SYNTHASE; SQUALENE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG; ZARAGOZIC ACID A;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; FERMENTATION; FUNGUS CULTURE; LIVER MICROSOME; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; RAT; TAXONOMY;

EID: 15644373055     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.50.1     Document Type: Article

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