Cyclopentenediones, inhibitors of farnesyl protein transferase and anti-tumor compounds, isolated from the fruit of Lindera erythrocarpa Makino

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 22, 2005, Pages 6182-6187

  Oh, Hyun Mi ^a,b   Choi, Sung Kyu ^a   Lee, Ji Min ^a   Lee, Su Kyung ^a   Kim, Hak Yung ^b   Han, Dong Cho ^a   Kim, Hwan Mook ^a   Son, Kwang Hee ^a   Kwon, Byoung Mog ^a,c  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungbuk National University   (South Korea)

^c University of Science and Technology (UST)   (South Korea)

Author keywords

Anti tumor; Cyclopentenediones; Farnesyl protein transferase; Lindera erythrocarpa

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CYCLOPENTENE DERIVATIVE; DOXIFLURIDINE; LINDERONE; LUCIDEONE; METHYLLINEDERONE; METHYLLUCIDONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; COLON ADENOCARCINOMA; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; FRUIT; HUMAN; HUMAN CELL; IC 50; LINDERA; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUDE MOUSE; ONCOGENE H RAS; PROTEIN DEGRADATION; RAT; STRUCTURE ANALYSIS; XENOGRAFT;

ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLOPENTANES; DRUG SCREENING ASSAYS, ANTITUMOR; FRUIT; HUMANS; LINDERA; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICE; MICE, NUDE; PHYTOTHERAPY; RATS;

LAURACEAE; LINDERA ERYTHROCARPA; MUS MUSCULUS;

EID: 25844489066     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.06.029     Document Type: Article

References (17)

1. M. Malumbres, and M. Barbacid Nat. Rev. Cancer 3 2003 459
2. K. Kato, A.D. Cox, M.M. Hisaka, S.M. Graham, J.E. Buss, and C.J. Der Proc. Natl. Acad. Sci. U.S.A. 89 1992 6403
3. J.B. Gibbs, A. Oliff, and N.E. Kohl Cell 77 1994 175
4. Y. Gibbs, F.L. Goldstein, M.C. Seabra, P.J. Casey, and M.S. Brown Cell 62 1990 81
5. J. Downward Nat. Rev. Cancer 3 2003 11
6. A. Oliff Biochim. Biophys. Acta 1423 1999 C19 C30
7. K. Zhu, A.D. Hamilton, and S.M. Sebti Curr. Opin. Investig. Drugs 4 2003 1428
8. R.J. Doll, P. Kirschmeier, and W.R. Bishop Curr. Opin. Drug Discov. Devel 7 2004 478
9. S.H. Lee, H.K. Kim, H.M. Kang, J.M. Seo, K.H. Son, H.S. Lee, and B.M. Kwon J. Org. Chem. 67 2002 7670
10. S.H. Lee, M.Y. Lee, H.M. Kang, D.C. Han, K.H. Son, D.C. Yang, N.D. Sung, C.W. Lee, H.M. Kim, and B.M. Kwon Bioorg. Med. Chem. 11 2003 4545
11. J.M. Seo, H.M. Kang, K.H. Son, J.H. Kim, C.W. Lee, H.M. Kim, S.I. Chang, and B.M. Kwon Planta Med. 69 2003 218 222
12. D.J. Newman, G.M. Cragg, and K.M. Snader J. Nat. Prod. 66 2003 1022
13. Y. Aoyama, T. Konoike, A. Kanda, N. Naya, and M.T. Nakajima Bioorg. Med. Chem. Lett. 11 2001 1695
14. Yuan-Wah Leong, Leslie J. Harrison, Graham J. Bennett, Azizol A. Kadir, and Joseph D. Connolly Phytochemistry 47 1998 891
15. S. Ng, H.H. Lee, and G.J. Bennett Magn. Reson. Chem. 28 1990 337
16. B.S. Min, K.H. Bae, Y.H. Kim, K. Shimotohno, H. Miyashiro, and M. Hattori Nat. Prod. Sci. 4 1998 241
17. Y. Shi Mol. Cell 9 2002 459