-
1
-
-
0022485201
-
CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: Tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species
-
TSUJITA, Y.; M. KURODA, Y. SHIMADA, K. TANZAWA, M. ARAI, I. KANEKO, M. TANAKA, H. MASUDA, C. TARUMI, Y. WATANABE & S. FUJII: CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species. Biochim. Biophys. Acta 877: 50-60, 1986
-
(1986)
Biochim. Biophys. Acta
, vol.877
, pp. 50-60
-
-
Tsujita, Y.1
Kuroda, M.2
Shimada, Y.3
Tanzawa, K.4
Arai, M.5
Kaneko, I.6
Tanaka, M.7
Masuda, H.8
Tarumi, C.9
Watanabe, Y.10
Fujii, S.11
-
2
-
-
0025120211
-
Regulation of the mevalonate pathway
-
GOLDSTEIN, J. L. & M. S. BROWN: Regulation of the mevalonate pathway. Nature 343: 425-430, 1990
-
(1990)
Nature
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
4
-
-
0026635536
-
Squalestatin 1, a competitive inhibitor of Squalene synthase, which lowers serum cholesterol in vivo
-
BAXTER, A.; B. J. FITZGERALD, J. L. HUTSON, A. D. MCCARTHY, J. M. MOTTERAM, B. C. ROSS, M. SAPRA, M. A. SNOWDEN, N. S. WATSON, R. J. WILLIAMS & C. WRIGHT: Squalestatin 1, a competitive inhibitor of Squalene synthase, which lowers serum cholesterol in vivo. J. Biol. Chem. 276: 11705-11708, 1992
-
(1992)
J. Biol. Chem.
, vol.276
, pp. 11705-11708
-
-
Baxter, A.1
Fitzgerald, B.J.2
Hutson, J.L.3
Mccarthy, A.D.4
Motteram, J.M.5
Ross, B.C.6
Sapra, M.7
Snowden, M.A.8
Watson, N.S.9
Williams, R.J.10
Wright, C.11
-
5
-
-
0027518332
-
Zaragozic acids: A family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase
-
BERGSTROM, J. D.; M. M. KURTZ, D. J. REW, A. M. AMEND, J. D. KARKAS, R. G. BOSTEDOR, V. S. BANSAL, C. DUFRESNE, F. L. VANMIDDLESWORTH, O. D. HENSENS, J. M. LIESCH, D. L. ZINK, K. E. WILSON, J. ONISHI, J. A. MILLIGAN, G. BILLS, L. KAPLAN, M. N. OMSTEAD, R. G. JENKINS, L. HUANG, M. S. MEINZ, L. QUINN, R. W. BURG, Y. L. KONG, S. MOCHALES, M. MOJENA, I. MARTIN, F. PELAEZ, M. T. DIEZ & A. W. ALBERTS: Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase. Proc. Natl. Acad. SCi. USA. 90: 80-84, 1993
-
(1993)
Proc. Natl. Acad. SCi. USA
, vol.90
, pp. 80-84
-
-
Bergstrom, J.D.1
Kurtz, M.M.2
Rew, D.J.3
Amend, A.M.4
Karkas, J.D.5
Bostedor, R.G.6
Bansal, V.S.7
Dufresne, C.8
Vanmiddlesworth, F.L.9
Hensens, O.D.10
Liesch, J.M.11
Zink, D.L.12
Wilson, K.E.13
Onishi, J.14
Milligan, J.A.15
Bills, G.16
Kaplan, L.17
Omstead, M.N.18
Jenkins, R.G.19
Huang, L.20
Meinz, M.S.21
Quinn, L.22
Burg, R.W.23
Kong, Y.L.24
Mochales, S.25
Mojena, M.26
Martin, I.27
Pelaez, F.28
Diez, M.T.29
Alberts, A.W.30
more..
-
6
-
-
0027217737
-
Competitive inhibition of squalene synthase by squalestatin 1
-
HASUMI, K.; K. TACHIKAWA, K. SAKAI, S. MURAKAWA, N. YOSHIKAWA, S. KUMAZAWA & A. ENDO: Competitive inhibition of squalene synthase by squalestatin 1. J. Antibiotics 46: 689-691, 1993
-
(1993)
J. Antibiotics
, vol.46
, pp. 689-691
-
-
Hasumi, K.1
Tachikawa, K.2
Sakai, K.3
Murakawa, S.4
Yoshikawa, N.5
Kumazawa, S.6
Endo, A.7
-
7
-
-
0029127323
-
Schizostatin, a potent squalene synthase inhibitor from Schizophyllum commune: Isolation, structure elucidation, and total synthesis
-
TANIMOTO, T.; Y. TSUJITA, K. HAMANO, H. HARUYAMA, T. KINOSHITA, T. HOSOYA, S. KANEKO, K. TAGO & H. KOGEN: Schizostatin, a potent squalene synthase inhibitor from Schizophyllum commune: Isolation, structure elucidation, and total synthesis. Tetrahedron Lett. 36: 6301-6304, 1995
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 6301-6304
-
-
Tanimoto, T.1
Tsujita, Y.2
Hamano, K.3
Haruyama, H.4
Kinoshita, T.5
Hosoya, T.6
Kaneko, S.7
Tago, K.8
Kogen, H.9
-
8
-
-
9344235429
-
Schizostatin, a novel squalene synthase inhibitor produced by the mushroom, Schizophyllum commune. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities
-
TANIMOTO, T.; K. ONODERA, T. HOSOYA, Y. TAKAMATSU, T. KINOSHITA, K. TAGO, H. KOGEN, T. FUJIOKA, K. HAMANO & Y. TSUJITA: Schizostatin, a novel squalene synthase inhibitor produced by the mushroom, Schizophyllum commune. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities J. Antibiotics 49: 617-623, 1996
-
(1996)
J. Antibiotics
, vol.49
, pp. 617-623
-
-
Tanimoto, T.1
Onodera, K.2
Hosoya, T.3
Takamatsu, Y.4
Kinoshita, T.5
Tago, K.6
Kogen, H.7
Fujioka, T.8
Hamano, K.9
Tsujita, Y.10
-
9
-
-
9344253815
-
Schizostatin, a novel squalene synthase inhibitor produced by the mushroom, Schizophyllum commune. II. Structure elucidation and total synthesis
-
KOGEN, H.; K. TAGO, S. KANEKO, K. HAMANO, K. ONODERA, H. HARUYAMA, K. MINAGAWA, T. KINOSHITA, T. ISHIKAWA, T. TANIMOTO & Y. TSUJITA: Schizostatin, a novel squalene synthase inhibitor produced by the mushroom, Schizophyllum commune. II. Structure elucidation and total synthesis J. Antibiotics 49: 624-630, 1996
-
(1996)
J. Antibiotics
, vol.49
, pp. 624-630
-
-
Kogen, H.1
Tago, K.2
Kaneko, S.3
Hamano, K.4
Onodera, K.5
Haruyama, H.6
Minagawa, K.7
Kinoshita, T.8
Ishikawa, T.9
Tanimoto, T.10
Tsujita, Y.11
-
10
-
-
0028841895
-
Discovery, biosynthesis, and mechanism of action of the zaragozic acids: Potent inhibitors of squalene synthase
-
BERGSTROM, J. D.; C. DUFRESNE, G. F. BILLS, M. NALLON-OMSTEAD & K. BYRNE: Discovery, biosynthesis, and mechanism of action of the zaragozic acids: Potent inhibitors of squalene synthase. Annu. Rev. Microbiol. 49: 607-639, 1995
-
(1995)
Annu. Rev. Microbiol.
, vol.49
, pp. 607-639
-
-
Bergstrom, J.D.1
Dufresne, C.2
Bills, G.F.3
Nallon-Omstead, M.4
Byrne, K.5
-
12
-
-
0027759397
-
The squalestatins: Potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety
-
WATSON, N. S.; R. BELL, C. CHAN, B. Cox, J. L. HUTSON, S. E. KEELING, B. E. KIRK, P. A. PROCOPIOU, I. P. STEEPLES & J. WIDDOUSON: The squalestatins: Potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety. Bioorg. Med. Chem. Lett. 12: 2541-2546, 1993
-
(1993)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 2541-2546
-
-
Watson, N.S.1
Bell, R.2
Chan, C.3
Cox, B.4
Hutson, J.L.5
Keeling, S.E.6
Kirk, B.E.7
Procopiou, P.A.8
Steeples, I.P.9
Widdouson, J.10
-
13
-
-
0027375980
-
Hepatoselective carrier-mediated sodium-independent uptake of pravastatin and pravastatin-lactone
-
ZIEGLER, K. & S. HUMMELSIEP: Hepatoselective carrier-mediated sodium-independent uptake of pravastatin and pravastatin-lactone. Biochim. Biophys. Acta 1153: 23-33, 1993
-
(1993)
Biochim. Biophys. Acta
, vol.1153
, pp. 23-33
-
-
Ziegler, K.1
Hummelsiep, S.2
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