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Volumn 50, Issue 5, 1997, Pages 390-394

Biological activities of novel zaragozic acids, the potent inhibitors of squalene synthase, produced by the fungus, Mollisia sp. SANK 10294

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; F 10863; HYPOCHOLESTEROLEMIC AGENT; SQUALENE SYNTHASE; SQUALENE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG; ZARAGOZIC ACID A; ZARAGOZIC ACID C;

EID: 0030943097     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.50.390     Document Type: Article
Times cited : (18)

References (13)
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    • TSUJITA, Y.; M. KURODA, Y. SHIMADA, K. TANZAWA, M. ARAI, I. KANEKO, M. TANAKA, H. MASUDA, C. TARUMI, Y. WATANABE & S. FUJII: CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species. Biochim. Biophys. Acta 877: 50-60, 1986
    • (1986) Biochim. Biophys. Acta , vol.877 , pp. 50-60
    • Tsujita, Y.1    Kuroda, M.2    Shimada, Y.3    Tanzawa, K.4    Arai, M.5    Kaneko, I.6    Tanaka, M.7    Masuda, H.8    Tarumi, C.9    Watanabe, Y.10    Fujii, S.11
  • 2
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • GOLDSTEIN, J. L. & M. S. BROWN: Regulation of the mevalonate pathway. Nature 343: 425-430, 1990
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 7
    • 0029127323 scopus 로고
    • Schizostatin, a potent squalene synthase inhibitor from Schizophyllum commune: Isolation, structure elucidation, and total synthesis
    • TANIMOTO, T.; Y. TSUJITA, K. HAMANO, H. HARUYAMA, T. KINOSHITA, T. HOSOYA, S. KANEKO, K. TAGO & H. KOGEN: Schizostatin, a potent squalene synthase inhibitor from Schizophyllum commune: Isolation, structure elucidation, and total synthesis. Tetrahedron Lett. 36: 6301-6304, 1995
    • (1995) Tetrahedron Lett. , vol.36 , pp. 6301-6304
    • Tanimoto, T.1    Tsujita, Y.2    Hamano, K.3    Haruyama, H.4    Kinoshita, T.5    Hosoya, T.6    Kaneko, S.7    Tago, K.8    Kogen, H.9
  • 8
    • 9344235429 scopus 로고    scopus 로고
    • Schizostatin, a novel squalene synthase inhibitor produced by the mushroom, Schizophyllum commune. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities
    • TANIMOTO, T.; K. ONODERA, T. HOSOYA, Y. TAKAMATSU, T. KINOSHITA, K. TAGO, H. KOGEN, T. FUJIOKA, K. HAMANO & Y. TSUJITA: Schizostatin, a novel squalene synthase inhibitor produced by the mushroom, Schizophyllum commune. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities J. Antibiotics 49: 617-623, 1996
    • (1996) J. Antibiotics , vol.49 , pp. 617-623
    • Tanimoto, T.1    Onodera, K.2    Hosoya, T.3    Takamatsu, Y.4    Kinoshita, T.5    Tago, K.6    Kogen, H.7    Fujioka, T.8    Hamano, K.9    Tsujita, Y.10
  • 10
    • 0028841895 scopus 로고
    • Discovery, biosynthesis, and mechanism of action of the zaragozic acids: Potent inhibitors of squalene synthase
    • BERGSTROM, J. D.; C. DUFRESNE, G. F. BILLS, M. NALLON-OMSTEAD & K. BYRNE: Discovery, biosynthesis, and mechanism of action of the zaragozic acids: Potent inhibitors of squalene synthase. Annu. Rev. Microbiol. 49: 607-639, 1995
    • (1995) Annu. Rev. Microbiol. , vol.49 , pp. 607-639
    • Bergstrom, J.D.1    Dufresne, C.2    Bills, G.F.3    Nallon-Omstead, M.4    Byrne, K.5
  • 13
    • 0027375980 scopus 로고
    • Hepatoselective carrier-mediated sodium-independent uptake of pravastatin and pravastatin-lactone
    • ZIEGLER, K. & S. HUMMELSIEP: Hepatoselective carrier-mediated sodium-independent uptake of pravastatin and pravastatin-lactone. Biochim. Biophys. Acta 1153: 23-33, 1993
    • (1993) Biochim. Biophys. Acta , vol.1153 , pp. 23-33
    • Ziegler, K.1    Hummelsiep, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.