Citrafungins A and B, Two New Fungal Metabolite Inhibitors of GGTase I with Antifungal Activity

Organic Letters

Volumn 6, Issue 3, 2004, Pages 337-340

  Singh, Sheo B ^a   Zink, Deborah L ^a   Doss, George A ^a   Polishook, Jon D ^a   Ruby, Carolyn ^a   Register, Elizabeth ^a   Kelly, Theresa M ^a   Bonfiglio, Cynthia ^a   Williamson, Joanne M ^a   Kelly, Rosemarie ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; CITRAFUNGIN A; CITRAFUNGIN B; CITRIC ACID; DRUG METABOLITE; ENZYME INHIBITOR; GERANYLTRANSFERASE; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME INHIBITION; EXTRACTION; FUNGAL STRAIN; IC 50; MINIMUM INHIBITORY CONCENTRATION; PATHOGENESIS; STEREOCHEMISTRY;

ALKENES; ALKYL AND ARYL TRANSFERASES; ANTIFUNGAL AGENTS; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; LACTONES; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 10744226252     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0361249     Document Type: Article

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