Arteminolide, an inhibitor of farnesyl transferase from Artemisia sylvatica

Journal of Organic Chemistry

Volumn 63, Issue 20, 1998, Pages 7111-7113

  Kirn, Mi Jeong ^a   Bok, Song Hae ^b   Kwon, Byoung Mog ^a,c   Shin, Jongheon ^a   Seo, Youngwan ^b  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea Research Institute of Ships and Ocean Engineering   (South Korea)

^c Chungbuk National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMINOLIDE; FARNESYL TRANS TRANSFERASE; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTEMISIA; ARTICLE; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PHYTOCHEMISTRY; PLANT LEAF; RAT;

EID: 0032476073     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo980919p     Document Type: Article

References (22)

1. Barbacid M. Annu. Rev. Biochem. 1987, 56, 779-827.
2. (a) Gibbs, J. B. Cell 1991, 65, 1-4 and references therein.
3. (b) Reiss, Y.; Goldstein, J. L.; Seabra, M. C.; Casey, P. J.; Brown, M. S. Cell 1990, 62, 81-88.
4. (a) Kato, K.; Cox, A. D.; Hisaka, M. M.; Graham, S. M.; Buss, J. E.; Der, C. J. Proc. Natl Acad. Sci. U.S.A. 1992, 89, 6403-6407.
5. (b) Casey, P. J.; Solski, P. A.; Der, C. J.; Buss, J. E. Proc. Natl. Acad. Sci. U.S.A. 1989, 86, 8323-8327.
6. For recent reviews, see: (a) Leonard D. M. J. Med. Chem. 1997, 40, 2971-2990 and references therein.
7. (b) Gibbs, J. B.; Oliff, A. Annu. Rev. Pharmacol. Toxicol. 1997, 37, 143-166.
8. (c) Cox, A. D.; Der, C. J. Biochim. Biophy. Acta 1997, 1333, F51-F71.
9. Kwon, B. M.; Cho, Y. K.; Lee, S. H.; Nam, J. Y.; Bok, S. H.; Chun, S. K.; Kirn, J. A.; Lee, I. R. Planta Med. 1996, 62, 183-184.
10. Seo, Y.; Cho, K. W.; Rho, J. R.; Shin, J.; Kwon, B. M.; Bok, S. H. Tetrahedron 1996, 52, 10583-10596.
11. Kwon, B. M.; Lee, S. H.; Kim, K. S.; Lee, I. R.; Lee, U. C.; Hong, S. H.; Bok, S. H. Bioorg. Med. Chem. Lett. 1997, 7, 971-974.
12. Marco, J. A.; Barbera, D. Studies in Natural Products Chemistry; Atta-ur-Rahman, Ed.; Elsevier: Amsterdam, 1990; pp 201-265.
13. (b) Valant-Vetschera, K M.; Wollenweber, E. Z. Naturforsch. 1995, 50c, 353-357.
14. For recent reviews, see: (a) Haynes, R. K.; Vonwiller, S. C. Ace. Chem. Res. 1997, 30, 73-79.
15. (b) Klayman, D. L. Science 1985, 228, 1049-1055.
16. (a) Robles, M.; Aregullin, M.; West, J.; Rodrigue, E. Planta Med. 1995, 61, 199-203.
17. (b) Pieman, A. K. Biochem. System. Ecol. 1986, 14, 255-281.
18. Chen, W. J.; Moomaw J. F., Overton, L. Kost, T. A.; Casey, P. J. J. Biol. Chem. 1993, 268, 9675-9680.
19. Jakupovic J.; Chen, Z. L.; Bohlmann, F. Phytochemistry 1987, 26, 2777-2779.
20. Orner, C. A.; Kohl, N. E. TiBS 1997, 18, 437-444 and references therein.
21. Patel, D. V.; Schmidt R. J.; Biller, S. A.; Gordon, E. M.; Robinson, S. S.; Manne, V. J. Med. Chem. 1995, 38, 2906-2921.
22. Agnew, W. S. Methods Enzymol. 1985, 110, 359-373.