Aplysamine 6, an alkaloidal inhibitor of isoprenylcysteine carboxyl methyltransferase from the sponge Pseudoceratina sp.

Journal of Natural Products

Volumn 71, Issue 6, 2008, Pages 1066-1067

  Buchanan, Malcolm S ^a   Carroll, Anthony R ^a   Fechner, Gregory A ^a   Boyle, Anthony ^a   Simpson, Moana ^a   Addepalli, Rama ^a   Avery, Vicky M ^a   Hooper, John N A ^b   Cheung, Tony ^c   Chen, Huwei ^c   Quinn, Ronald J ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b QUEENSLAND MUSEUM   (Australia)

^c ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APLYSAMINE 6; METHYLTRANSFERASE INHIBITOR; PROTEIN S ISOPRENYLCYSTEINE O METHYLTRANSFERASE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOCERATINA; SPONGE (PORIFERA); STRUCTURE ANALYSIS;

ANIMALS; AUSTRALIA; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PORIFERA; PROTEIN METHYLTRANSFERASES; TYROSINE;

PSEUDOCERATINA;

EID: 47549105779     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np0706623     Document Type: Article

References (7)

1. Winter-Vann, A. M.; Casey, P. J. Nat. Rev. Cancer 2005, 5, 405-412.
2. Winter-Vann, A. M.; Baron, R. A.; Wong, W.; Dela Cruz, J.; York, J. D.; Gooden, D. M.; Bergo, M. O.; Young, S. G.; Toone, E. J.; Casey, P. J. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 4336-4341.
3. Buchanan, M. S.; Carroll, A. R.; Fechner, G. A.; Boyle, A.; Simpson, M.; Addepalli, R.; Avery, V. M.; Hooper, J. N. A.; Su, N.; ChenH.; Quinn, R. J. Bioorg. Med. Chem. Lett. 2007, 17, 6860-6863.
4. Tilvi, S.; Rodrigues, C.; Naik, C. G.; Parameswaran, P. S.; Wahidhulla, S. Tetrahedron 2004, 60, 10207-10215.
5. Schroeder, F. C.; Kau, T. R.; Silver, P. A.; Clardy, J. J. Nat. Prod. 2005, 68, 574-576.
6. Jurek, J.; Yoshida, W. Y.; Scheuer, P. J. J. Nat. Prod. 1993, 56, 1609-1612.
7. Yagi, H.; Matsunaga, S.; Fusetani, N. Tetrahedron 1993, 49, 3749-3754.