Small-molecule inhibitors of the cancer target, isoprenylcysteine carboxyl methyltransferase, from Hovea parvicalyx

Phytochemistry

Volumn 69, Issue 9, 2008, Pages 1886-1889

  Buchanan, Malcolm S ^a   Carroll, Anthony R ^a   Fechner, Gregory A ^a   Boyle, Anthony ^a   Simpson, Moana ^a   Addepalli, Rama ^a   Avery, Vicky M ^a   Forster, Paul I ^b   Guymer, Gordon P ^b   Cheung, Tony ^c   Chen, Huwei ^c   Quinn, Ronald J ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b QUEENSLAND HERBARIUM   (Australia)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Hydroxychalcone; 2 Methoxy 3 prenyl licodione; 2 Methoxy 3 3 diprenyl licodione; Fabaceae; Hovea parvicalyx; Isoprenylcysteine carboxyl methyltransferase (Icmt); Structure elucidation

Indexed keywords

ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; PROTEIN METHYLTRANSFERASE; PROTEIN S ISOPRENYLCYSTEINE O METHYLTRANSFERASE; PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; LEGUME; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANTINEOPLASTIC AGENTS; ENZYME INHIBITORS; FABACEAE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PROTEIN METHYLTRANSFERASES;

FABACEAE; HOVEA;

EID: 44549085002     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2008.04.011     Document Type: Article

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