-
1
-
-
0028170814
-
Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes
-
Glomset, J. A. & Farnsworth, C. C. Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes. Annu. Rev. Cell Biol. 10, 181-205 (1994).
-
(1994)
Annu. Rev. Cell Biol.
, vol.10
, pp. 181-205
-
-
Glomset, J.A.1
Farnsworth, C.C.2
-
2
-
-
0029898894
-
Protein prenylation: Molecular mechanisms and functional consequences
-
Zhang, F. L. & Casey, P. J. Protein prenylation: molecular mechanisms and functional consequences. Annu. Rev. Biochem. 65, 241-269 (1996).
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 241-269
-
-
Zhang, F.L.1
Casey, P.J.2
-
3
-
-
0029966304
-
Protein prenyltransferases
-
Casey, P. J. & Seabra, M. C. Protein prenyltransferases. J. Biol. Chem. 271, 5289-5292 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5289-5292
-
-
Casey, P.J.1
Seabra, M.C.2
-
4
-
-
0031945668
-
CaaX converting enzymes
-
Ashby, M. N. CaaX converting enzymes. Curr. Opin. Lipidol. 9, 99-102 (1998).
-
(1998)
Curr. Opin. Lipidol.
, vol.9
, pp. 99-102
-
-
Ashby, M.N.1
-
5
-
-
0000332878
-
-
eds Tamanoi, F. and Sigman, D. G. Academic, San Diego
-
Young, S. G., Ambroziack, P., Kim, E. & Clarke, S. in The Enzymes 3rd edn Vol. 21 (eds Tamanoi, F. and Sigman, D. G.) 156-213 (Academic, San Diego, 2001).
-
(2001)
The Enzymes 3rd Edn
, vol.21
, pp. 156-213
-
-
Young, S.G.1
Ambroziack, P.2
Kim, E.3
Clarke, S.4
-
6
-
-
0024376173
-
ras oncogenes in human cancer: A review
-
Bos, J. L. ras oncogenes in human cancer: a review. Cancer Rss. 49, 4682-4689 (1989).
-
(1989)
Cancer Rss.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
8
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn, W. C. et al. Creation of human tumour cells with defined genetic elements. Nature 400, 464-468 (1999).
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
-
9
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger, J. Cell signaling by receptor tyrosine kinases. Cell 103, 211-225 (2000).
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
10
-
-
2342591455
-
The discovery of receptor tyrosine kinases: Targets for cancer therapy
-
Gschwind, A., Fischer, O. M. & Ullrich, A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nature Rev. Cancer 4, 361-370 (2004).
-
(2004)
Nature Rev. Cancer
, vol.4
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
11
-
-
0036191304
-
Rho GTPases in transformation and metastasis
-
Jaffe, A. B. & Hall, A. Rho GTPases in transformation and metastasis. Adv. Cancer Res. 84, 57-80 (2002).
-
(2002)
Adv. Cancer Res.
, vol.84
, pp. 57-80
-
-
Jaffe, A.B.1
Hall, A.2
-
13
-
-
10744228326
-
Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice
-
Ishida, D. et al. Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice. Cancer Cell 4, 55-65 (2003).
-
(2003)
Cancer Cell
, vol.4
, pp. 55-65
-
-
Ishida, D.1
-
14
-
-
1542290456
-
G proteins in cancer: The prostate cancer paradigm
-
Daaka, Y. G proteins in cancer: the prostate cancer paradigm. Sci. STKE 216, re2 (2004).
-
(2004)
Sci. STKE
, vol.216
-
-
Daaka, Y.1
-
15
-
-
0037180757
-
Inflammation and cancer
-
Coussens, L. M. & Werb, Z. Inflammation and cancer. Nature 420, 860-867 (2002).
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
16
-
-
0035952766
-
Heterotrimeric G-protein βγ-dimers in growth and differentiation
-
Schwindinger, W. F. & Robishaw, J. D. Heterotrimeric G-protein βγ-dimers in growth and differentiation. Oncogene 20, 1653-1660 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 1653-1660
-
-
Schwindinger, W.F.1
Robishaw, J.D.2
-
17
-
-
0035952679
-
Autocrine and paracrine signaling through neuropeptide receptors in human cancer
-
Heasley, L. E. Autocrine and paracrine signaling through neuropeptide receptors in human cancer. Oncogene 20, 1563-1569 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 1563-1569
-
-
Heasley, L.E.1
-
19
-
-
0030596111
-
Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases
-
Cates, C. A. et al. Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases. Cancer Lett. 110, 49-55 (1996).
-
(1996)
Cancer Lett.
, vol.110
, pp. 49-55
-
-
Cates, C.A.1
-
20
-
-
0034141636
-
LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo
-
Collins, S. P., Reoma, J. L., Gamm, D. M. & Uhler, M. D. LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo. Biochem. J. 345, 673-580 (2000).
-
(2000)
Biochem. J.
, vol.345
, pp. 673-1580
-
-
Collins, S.P.1
Reoma, J.L.2
Gamm, D.M.3
Uhler, M.D.4
-
21
-
-
0036843975
-
Lamins: Building blocks or regulators of gene expression?
-
Hutchison, C. J. Lamins: building blocks or regulators of gene expression? Nature Rev. Mol. Cell Biol. 3, 848-858 (2002).
-
(2002)
Nature Rev. Mol. Cell Biol.
, vol.3
, pp. 848-858
-
-
Hutchison, C.J.1
-
22
-
-
0034730625
-
Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules
-
Ashar, H. R. et al. Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules. J. Biol. Chem. 275, 30451-30457 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30451-30457
-
-
Ashar, H.R.1
-
23
-
-
3042559944
-
Prenyl-binding domains: Potential targets for Ras inhibitors and anti-cancer drugs
-
Kloog, Y. & Cox, A. D. Prenyl-binding domains: potential targets for Ras inhibitors and anti-cancer drugs. Semin. Cancer Biol. 14, 253-261 (2004).
-
(2004)
Semin. Cancer Biol.
, vol.14
, pp. 253-261
-
-
Kloog, Y.1
Cox, A.D.2
-
24
-
-
0026747866
-
Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity
-
Kato, K. et al. Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. Proc. Natl Acad. Sci. USA 89, 6403-6407 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6403-6407
-
-
Kato, K.1
-
25
-
-
0025906597
-
Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins
-
Hori, Y. et al. Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins. Oncogene 6, 515-522 (1991).
-
(1991)
Oncogene
, vol.6
, pp. 515-522
-
-
Hori, Y.1
-
26
-
-
0034613286
-
RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription
-
Allal, C. et al. RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription. J. Biol. Chem. 275, 31001-31008 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31001-31008
-
-
Allal, C.1
-
27
-
-
0025046234
-
Farnesylated γ-subunit of photoreceptor G protein indispensable for GTP-binding
-
Fukada, Y. et al. Farnesylated γ-subunit of photoreceptor G protein indispensable for GTP-binding. Nature 346, 658-660 (1990).
-
(1990)
Nature
, vol.346
, pp. 658-660
-
-
Fukada, Y.1
-
28
-
-
0028331587
-
Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic
-
Gibbs, J. B., Oliff, A. & Kohl, N. E. Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic. Cell 77, 175-178 (1994).
-
(1994)
Cell
, vol.77
, pp. 175-178
-
-
Gibbs, J.B.1
Oliff, A.2
Kohl, N.E.3
-
29
-
-
1542328237
-
Perspectives on farnesyl transferase inhibitors in cancer therapy
-
Mazieres, J., Pradines, A. & Favre, G. Perspectives on farnesyl transferase inhibitors in cancer therapy. Cancer Lett. 206, 159-167 (2004).
-
(2004)
Cancer Lett.
, vol.206
, pp. 159-167
-
-
Mazieres, J.1
Pradines, A.2
Favre, G.3
-
30
-
-
0029150669
-
Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice
-
Kohl, N. E. et al. Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice. Nature Med. 1, 792-797 (1995).
-
(1995)
Nature Med.
, vol.1
, pp. 792-797
-
-
Kohl, N.E.1
-
31
-
-
4644362784
-
Farnesyltransferase inhibitors as anticancer agents: Critical crossroads
-
Doll, R. J., Kirschmeier, P. & Bishop, W. R. Farnesyltransferase inhibitors as anticancer agents: critical crossroads. Curr. Opin. Drug Discov. Devel. 7, 478-486 (2004).
-
(2004)
Curr. Opin. Drug Discov. Devel.
, vol.7
, pp. 478-486
-
-
Doll, R.J.1
Kirschmeier, P.2
Bishop, W.R.3
-
32
-
-
17144361932
-
Farnesyltransferase inhibitor therapy in acute myelogenous leukemia
-
Gotlib, J. Farnesyltransferase inhibitor therapy in acute myelogenous leukemia. Curr. Hematol. Rep. 4, 77-84 (2005).
-
(2005)
Curr. Hematol. Rep.
, vol.4
, pp. 77-84
-
-
Gotlib, J.1
-
33
-
-
0036667388
-
Farnesyltransferase inhibitors: Promises and realities
-
Cox, A. D. & Der, C. J. Farnesyltransferase inhibitors: promises and realities. Curr. Opin. Pharmacol. 2, 388-393 (2002).
-
(2002)
Curr. Opin. Pharmacol.
, vol.2
, pp. 388-393
-
-
Cox, A.D.1
Der, C.J.2
-
34
-
-
0028958919
-
Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro
-
James, G. L., Goldstein, J. L. & Brown, M. S. Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro. J. Biol. Chem. 270, 6221-6226 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6221-6226
-
-
James, G.L.1
Goldstein, J.L.2
Brown, M.S.3
-
35
-
-
0030923192
-
K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors
-
Whyte, D. B. et al. K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors. J. Biol. Chem. 272, 14459-14464 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14459-14464
-
-
Whyte, D.B.1
-
36
-
-
1342331479
-
Searching for the elusive targets of farnesyltransferase inhibitors
-
Sebti, S. M. & Der, C. J. Searching for the elusive targets of farnesyltransferase inhibitors. Nature Rev. Cancer 3, 945-951 (2003).
-
(2003)
Nature Rev. Cancer
, vol.3
, pp. 945-951
-
-
Sebti, S.M.1
Der, C.J.2
-
37
-
-
0033605596
-
Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells
-
Kim, E. et al. Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells. J. Biol. Chem. 274, 8383-8390 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8383-8390
-
-
Kim, E.1
-
38
-
-
0034625181
-
Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells
-
Bergo, M. O. et al. Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells. J. Biol. Chem. 275, 17605-17610 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17605-17610
-
-
Bergo, M.O.1
-
39
-
-
1642340687
-
Fighting cancer by disrupting C-terminal methylation of signaling proteins
-
Clarke, S. & Tamanoi, F. Fighting cancer by disrupting C-terminal methylation of signaling proteins. J. Clin. Invest. 113, 513-515 (2004).
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 513-515
-
-
Clarke, S.1
Tamanoi, F.2
-
40
-
-
0030909336
-
Modulation of Ras and a-factor function by carboxyl-terminal proteolysis
-
Boyartchuk, V. L., Ashby, M. N. & Rine, J. Modulation of Ras and a-factor function by carboxyl-terminal proteolysis. Science 275, 1796-1800 (1997).
-
(1997)
Science
, vol.275
, pp. 1796-1800
-
-
Boyartchuk, V.L.1
Ashby, M.N.2
Rine, J.3
-
41
-
-
0033605743
-
Cloning and characterization of a mammalian prenyl protein-specific protease
-
Otto, J. C., Kim, E., Young, S. G. & Casey, P. J. Cloning and characterization of a mammalian prenyl protein-specific protease. J. Biol. Chem. 274, 8379-8382 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8379-8382
-
-
Otto, J.C.1
Kim, E.2
Young, S.G.3
Casey, P.J.4
-
42
-
-
0032530150
-
Endoplasmic reticulum membrane localization of Rce1 p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage
-
Schmidt, W. K., Tam, A., Fujimura-Kamada, K. & Michaelis, S. Endoplasmic reticulum membrane localization of Rce1 p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage. Proc. Natl Acad. Sci. USA 95, 11175-11180 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11175-11180
-
-
Schmidt, W.K.1
Tam, A.2
Fujimura-Kamada, K.3
Michaelis, S.4
-
43
-
-
0032584323
-
Substrate specificity of mammalian prenyl protein-specific endoprotease activity
-
Jang, G. F. & Gelb, M. H. Substrate specificity of mammalian prenyl protein-specific endoprotease activity. Biochemistry 37, 4473-4481 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 4473-4481
-
-
Jang, G.F.1
Gelb, M.H.2
-
44
-
-
0029990398
-
Solubilization, partial purification, and affinity labeling of the membrane-bound isoprenylated protein endoprotease
-
Chen, Y., Ma, Y. T. & Rando, R. R. Solubilization, partial purification, and affinity labeling of the membrane-bound isoprenylated protein endoprotease. Biochemistry 35, 3227-3237 (1996).
-
(1996)
Biochemistry
, vol.35
, pp. 3227-3237
-
-
Chen, Y.1
Ma, Y.T.2
Rando, R.R.3
-
45
-
-
0035339494
-
Type II CAAX prenyl endopeptidases belong to a novel superfamily of putative membrane-bound metalloproteases
-
Pei, J. & Grishin, N. V. Type II CAAX prenyl endopeptidases belong to a novel superfamily of putative membrane-bound metalloproteases. Trends Biochem. Sci. 26, 275-277 (2001).
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 275-277
-
-
Pei, J.1
Grishin, N.V.2
-
46
-
-
0034119314
-
The CaaX proteases, Afcip and Rce1p, have overlapping but distinct substrate specificities
-
Trueblood, C. E. et al. The CaaX proteases, Afcip and Rce1p, have overlapping but distinct substrate specificities. Mol. Cell. Biol. 20, 4381-4392 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4381-4392
-
-
Trueblood, C.E.1
-
47
-
-
1042266632
-
On the physiological importance of endoproteolysis of CAAX proteins: Heart-specific RCE1 knockout mice develop a lethal cardiomyopathy
-
Bergo, M. O. et al. On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy. J. Biol. Chem. 279, 4729-4736 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4729-4736
-
-
Bergo, M.O.1
-
48
-
-
0032511057
-
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
-
Dai, Q. et al. Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum. J. Biol. Chem. 273, 15030-15034 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15030-15034
-
-
Dai, Q.1
-
49
-
-
0031858844
-
The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane
-
Romano, J. D., Schmidt, W. K. & Michaelis, S. The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane. Mol. Biol. Cell 9, 2231-2247 (1998).
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 2231-2247
-
-
Romano, J.D.1
Schmidt, W.K.2
Michaelis, S.3
-
50
-
-
0025203977
-
Saccharomyces cerevisiae STE14 gene is required for COOH-terminal methylation of a-factor mating pheromone
-
Marr, R. S., Blair, L. C. & Thorner, J. Saccharomyces cerevisiae STE14 gene is required for COOH-terminal methylation of a-factor mating pheromone. J. Biol. Chem. 265, 20057-20060 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20057-20060
-
-
Marr, R.S.1
Blair, L.C.2
Thorner, J.3
-
51
-
-
0025764049
-
The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins
-
Hrycyna, C. A., Sapperstein, S. K., Clarke, S. & Michaelis, S. The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins. EMBO J. 10, 1699-1709 (1991).
-
(1991)
EMBO J.
, vol.10
, pp. 1699-1709
-
-
Hrycyna, C.A.1
Sapperstein, S.K.2
Clarke, S.3
Michaelis, S.4
-
52
-
-
0028179364
-
Widespread occurrence of three sequence motifs in diverse S-adenosylmethionine-dependent methyltransferases suggests a common structure for these enzymes
-
Kagan, R. M. & Clarke, S. Widespread occurrence of three sequence motifs in diverse S-adenosylmethionine-dependent methyltransferases suggests a common structure for these enzymes. Arch. Biochem. Biophys. 310, 417-427 (1994).
-
(1994)
Arch. Biochem. Biophys.
, vol.310
, pp. 417-427
-
-
Kagan, R.M.1
Clarke, S.2
-
53
-
-
0025870323
-
Identifying the recognition unit for G protein methylation
-
Tan, E. W., Perez-Sala, D., Canada, F. J. & Rando, R. R. Identifying the recognition unit for G protein methylation. J. Biol. Chem. 266, 10719-10722 (1991).
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 10719-10722
-
-
Tan, E.W.1
Perez-Sala, D.2
Canada, F.J.3
Rando, R.R.4
-
54
-
-
0036301339
-
Prenylcysteine carboxylmethyltransferase is essential for the earliest stages of liver development in mice
-
Lin, X. et al. Prenylcysteine carboxylmethyltransferase is essential for the earliest stages of liver development in mice. Gastroenterology 123, 345-351 (2002).
-
(2002)
Gastroenterology
, vol.123
, pp. 345-351
-
-
Lin, X.1
-
55
-
-
0035937112
-
Isoprenylcysteine carboxyl methyltransferase deficiency in mice
-
Bergo, M. O. et al. Isoprenylcysteine carboxyl methyltransferase deficiency in mice. J. Biol. Chem. 276, 5841-5845 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5841-5845
-
-
Bergo, M.O.1
-
56
-
-
0028153018
-
Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro
-
Smeland, T. E., Seabra, M. C., Goldstein, J. L. & Brown, M. S. Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro. Proc. Natl Acad. Sci. USA 91, 10712-10716 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10712-10716
-
-
Smeland, T.E.1
Seabra, M.C.2
Goldstein, J.L.3
Brown, M.S.4
-
57
-
-
0035135929
-
Small GTP-binding proteins
-
Takai, Y., Sasaki, T. & Matozaki, T. Small GTP-binding proteins. Physiol. Rev. 81, 153-208 (2001).
-
(2001)
Physiol. Rev.
, vol.81
, pp. 153-208
-
-
Takai, Y.1
Sasaki, T.2
Matozaki, T.3
-
58
-
-
0028196986
-
Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers
-
Silvius, J. R. & l'Heureux, F. Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers. Biochemistry 33, 3014-3022 (1994).
-
(1994)
Biochemistry
, vol.33
, pp. 3014-3022
-
-
Silvius, J.R.1
L'Heureux, F.2
-
59
-
-
0034731405
-
The C-terminal polylysine region and methylation of K-Ras are critical for the interaction between K-Ras and microtubules
-
Chen, Z., Otto, J. C., Bergo, M. O., Young, S. G. & Casey, P. J. The C-terminal polylysine region and methylation of K-Ras are critical for the interaction between K-Ras and microtubules. J. Biol. Chem. 275, 41251-41257 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 41251-41257
-
-
Chen, Z.1
Otto, J.C.2
Bergo, M.O.3
Young, S.G.4
Casey, P.J.5
-
60
-
-
0036732940
-
Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi
-
Michaelson, D., Ahearn, I., Bergo, M., Young, S. & Philips, M. Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi. Mol. Biol. Cell 13, 3294-3302 (2002).
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3294-3302
-
-
Michaelson, D.1
Ahearn, I.2
Bergo, M.3
Young, S.4
Philips, M.5
-
61
-
-
16344396081
-
Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases
-
in the press
-
Michaelson, D. et al. Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases. Mol. Biol. Cell (in the press).
-
Mol. Biol. Cell
-
-
Michaelson, D.1
-
62
-
-
0025051169
-
Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae
-
Hrycyna, C. A. & Clarke, S. Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae. Mol. Cell. Biol. 10, 5071-5076 (1990).
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 5071-5076
-
-
Hrycyna, C.A.1
Clarke, S.2
-
63
-
-
0028125792
-
Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export
-
Sapperstein, S., Berkower, C. & Michaelis, S. Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export. Mol. Cell. Biol. 14, 1438-1449 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1438-1449
-
-
Sapperstein, S.1
Berkower, C.2
Michaelis, S.3
-
64
-
-
0029075550
-
Functional significance of βγ subunit carboxymethylation for the activation of phospholipase C and phosphoinositide 3-kinase
-
Parish, C. A., Smrcka, A. V. & Rando, R. R. Functional significance of βγ subunit carboxymethylation for the activation of phospholipase C and phosphoinositide 3-kinase. Biochemistry 34, 7722-7727 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 7722-7727
-
-
Parish, C.A.1
Smrcka, A.V.2
Rando, R.R.3
-
65
-
-
0027983602
-
Effects of carboxyl methylation of photoreceptor G protein γ subunit in visual transduction
-
Fukada, Y. et al. Effects of carboxyl methylation of photoreceptor G protein γ subunit in visual transduction. J. Biol. Chem. 269, 5163-5170 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 5163-5170
-
-
Fukada, Y.1
-
66
-
-
0141530040
-
A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation
-
Maske, C. P. et al. A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation. J. Cell Biol. 162, 1223-1232 (2003).
-
(2003)
J. Cell Biol.
, vol.162
, pp. 1223-1232
-
-
Maske, C.P.1
-
67
-
-
2042544816
-
Post-translational processing of RhoA. Carboxyl methylation of the carboxyl-terminal prenylcysteine increases the half-life of RhoA
-
Backlund, P. S. Jr. Post-translational processing of RhoA. Carboxyl methylation of the carboxyl-terminal prenylcysteine increases the half-life of RhoA. J. Biol Chem. 272, 33175-33180 (1997).
-
(1997)
J. Biol Chem.
, vol.272
, pp. 33175-33180
-
-
Backlund Jr., P.S.1
-
68
-
-
1642326112
-
Inactivation of lcmt inhibits transformation by oncogenic K-Ras and B-Raf
-
Bergo, M. O. et al. Inactivation of lcmt inhibits transformation by oncogenic K-Ras and B-Raf. J. Clin. Invest. 113, 539-550 (2004).
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 539-550
-
-
Bergo, M.O.1
-
69
-
-
0027537491
-
Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils
-
Philips, M. R. et al. Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils. Science 259, 977-980 (1993).
-
(1993)
Science
, vol.259
, pp. 977-980
-
-
Philips, M.R.1
-
70
-
-
0942268920
-
Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR
-
Perez, E., West, A. H., Stock, A. M. & Djordjevic, S. Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR. Biochemistry 43, 953-961 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 953-961
-
-
Perez, E.1
West, A.H.2
Stock, A.M.3
Djordjevic, S.4
-
71
-
-
0004258020
-
Methylation of a membrane protein involved in bacterial chemotaxis
-
Kort, E. N., Goy, M. F., Larsen, S. H. & Adler, J. Methylation of a membrane protein involved in bacterial chemotaxis. Proc. Natl Acad. Sci. USA 72, 3939-3943 (1975).
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 3939-3943
-
-
Kort, E.N.1
Goy, M.F.2
Larsen, S.H.3
Adler, J.4
-
72
-
-
0035072252
-
Assays of human postprenylation processing enzymes
-
Choi, Y. J. et al. Assays of human postprenylation processing enzymes. Methods Enzymol. 332, 103-114 (2001).
-
(2001)
Methods Enzymol.
, vol.332
, pp. 103-114
-
-
Choi, Y.J.1
-
73
-
-
0026740602
-
Identification of an isoprenylated cysteine methyl ester hydrolase activity in bovine rod outer segment membranes
-
Tan, E. W. & Rando, R. R. Identification of an isoprenylated cysteine methyl ester hydrolase activity in bovine rod outer segment membranes. Biochemistry 31, 5572-5578 (1992).
-
(1992)
Biochemistry
, vol.31
, pp. 5572-5578
-
-
Tan, E.W.1
Rando, R.R.2
-
74
-
-
0028897903
-
Fractionation and characterization of protein C-terminal prenyl-cysteine methylesterase activities from rabbit brain
-
Dunten, R. L., Wait, S. J. & Backlund, P. S. Jr. Fractionation and characterization of protein C-terminal prenyl-cysteine methylesterase activities from rabbit brain. Biochem. Biophys. Res. Commun. 208, 174-182 (1995).
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.208
, pp. 174-182
-
-
Dunten, R.L.1
Wait, S.J.2
Backlund Jr., P.S.3
-
75
-
-
0036132907
-
Absence of the CAAX endoprotease Rce1: Effects on cell growth and transformation
-
Bergo, M. O. et al. Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation. Mol. Cell. Biol. 22, 171-181 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 171-181
-
-
Bergo, M.O.1
-
76
-
-
0037443394
-
Hematologic effects of inactivating the Ras processing enzyme Rce1
-
Alyagari, A. L., Taylor, B. R., Aurora, V., Young, S. G. & Shannon, K. M. Hematologic effects of inactivating the Ras processing enzyme Rce1. Blood 101, 2250-2252 (2003).
-
(2003)
Blood
, vol.101
, pp. 2250-2252
-
-
Alyagari, A.L.1
Taylor, B.R.2
Aurora, V.3
Young, S.G.4
Shannon, K.M.5
-
77
-
-
0035847663
-
Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1
-
Schlitzer, M., Winter-Vann, A. & Casey, P. J. Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1. Bioorg. Med. Chem. Lett. 11, 425-427 (2001).
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 425-427
-
-
Schlitzer, M.1
Winter-Vann, A.2
Casey, P.J.3
-
78
-
-
0027518956
-
Inhibitors of the isoprenylated protein endoprotease
-
Ma, Y. T., Gilbert, B. A. & Rando, R. R. Inhibitors of the isoprenylated protein endoprotease. Biochemistry 32, 2386-2393 (1993).
-
(1993)
Biochemistry
, vol.32
, pp. 2386-2393
-
-
Ma, Y.T.1
Gilbert, B.A.2
Rando, R.R.3
-
79
-
-
0033452547
-
Selective inhibition of Ras-transformed cell growth by a novel fatty acid-based chloromethyl ketone designed to target Ras endoprotease
-
Chen, Y. Selective inhibition of Ras-transformed cell growth by a novel fatty acid-based chloromethyl ketone designed to target Ras endoprotease. Ann. NY Acad. Sci. 886, 103-108 (1999).
-
(1999)
Ann. NY Acad. Sci.
, vol.886
, pp. 103-108
-
-
Chen, Y.1
-
80
-
-
0026630109
-
Kinetic mechanism of isoprenylated protein methyltransferase
-
Shi, Y. Q. & Rando, R. R. Kinetic mechanism of isoprenylated protein methyltransferase. J. Biol. Chem. 267, 9547-9551 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 9547-9551
-
-
Shi, Y.Q.1
Rando, R.R.2
-
81
-
-
0037637529
-
Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate
-
Winter-Vann, A. M. et al. Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate. Proc. Natl Acad. Sci. USA 100, 6529-6534 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6529-6534
-
-
Winter-Vann, A.M.1
-
82
-
-
0030610589
-
ras methylation in vascular endothelial cells by homocysteine but not cysteine
-
ras methylation in vascular endothelial cells by homocysteine but not cysteine. J. Biol. Chem. 272, 25380-25385 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25380-25385
-
-
Wang, H.1
-
83
-
-
0037342399
-
Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis
-
Kramer, K. et al. Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis. Mol. Biol. Cell 14, 848-857 (2003).
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 848-857
-
-
Kramer, K.1
-
84
-
-
1242297570
-
Isoprenylcysteine carboxyl methyltransferase modulates endothelial monolayer permeability. Involvement of RhoA carboxyl methylation
-
Lu, Q. et al. Isoprenylcysteine carboxyl methyltransferase modulates endothelial monolayer permeability. Involvement of RhoA carboxyl methylation. Circ. Res. 94, 306-315 (2004).
-
(2004)
Circ. Res.
, vol.94
, pp. 306-315
-
-
Lu, Q.1
-
85
-
-
0018378083
-
Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions
-
Hoffman, D. R., Cornatzer, W. E. & Duerre, J. A. Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions. Can. J. Biochem. 57, 56-65 (1979).
-
(1979)
Can. J. Biochem.
, vol.57
, pp. 56-65
-
-
Hoffman, D.R.1
Cornatzer, W.E.2
Duerre, J.A.3
-
86
-
-
0029926820
-
S-adenosylmethionine and methylation
-
Chiang, P. K. et al. S-adenosylmethionine and methylation. FASEB J. 10, 471-480 (1996).
-
(1996)
FASEB J.
, vol.10
, pp. 471-480
-
-
Chiang, P.K.1
-
87
-
-
0026748625
-
Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates
-
Perez-Sala, D., Gilbert, B. A., Tan, E. W. & Rando, R. R. Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates. Biochem. J. 284, 835-840 (1992).
-
(1992)
Biochem. J.
, vol.284
, pp. 835-840
-
-
Perez-Sala, D.1
Gilbert, B.A.2
Tan, E.W.3
Rando, R.R.4
-
88
-
-
0030056516
-
Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure β cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion
-
Kowluru, A. et al. Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure β cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion. J. Clin. Invest. 98, 540-555 (1996).
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 540-555
-
-
Kowluru, A.1
-
89
-
-
1342304078
-
Carboxyl methylation of ras regulates membrane targeting and effector engagment
-
Chiu, V. K. et al. Carboxyl methylation of ras regulates membrane targeting and effector engagment. J. Biol. Chem. 279, 7346-7352 (2003).
-
(2003)
J. Biol. Chem.
, vol.279
, pp. 7346-7352
-
-
Chiu, V.K.1
-
90
-
-
0029931495
-
Farnesyl analogues inhibit vasoconstriction in animal and human arteries
-
Roullet, J. B. et al. Farnesyl analogues inhibit vasoconstriction in animal and human arteries. J. Clin. Invest. 97, 2384-2390 (1996).
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2384-2390
-
-
Roullet, J.B.1
-
91
-
-
0027510182
-
Farnesylcysteine analogues inhibit chemotactic peptide receptor-mediated G-protein activation in human HL-60 granulocyte membranes
-
Scheer, A. & Gierschik, P. Farnesylcysteine analogues inhibit chemotactic peptide receptor-mediated G-protein activation in human HL-60 granulocyte membranes. FEBS Lett. 319, 110-114 (1993).
-
(1993)
FEBS Lett.
, vol.319
, pp. 110-114
-
-
Scheer, A.1
Gierschik, P.2
-
92
-
-
0028234889
-
Mechanistic studies on human platelet isoprenylated protein methyltransferase: Farnesylcysteine analogs block platelet aggregation without inhibiting the methyltransferase
-
Ma, Y. T. et al. Mechanistic studies on human platelet isoprenylated protein methyltransferase: farnesylcysteine analogs block platelet aggregation without inhibiting the methyltransferase. Biochemistry 33, 5414-5420 (1994).
-
(1994)
Biochemistry
, vol.33
, pp. 5414-5420
-
-
Ma, Y.T.1
-
93
-
-
0028246072
-
Farnesyl-L-cysteine analogs can inhibit or initiate superoxide release by human neutrophils
-
Ding, J. et al. Farnesyl-L-cysteine analogs can inhibit or initiate superoxide release by human neutrophils. J. Biol. Chem. 269, 16837-16844 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16837-16844
-
-
Ding, J.1
-
94
-
-
2442669390
-
Methotrexate and Ras methylation: A new trick for an old drug?
-
Philips, M. R. Methotrexate and Ras methylation: a new trick for an old drug? Sci. STKE 225, pe13 (2004).
-
(2004)
Sci. STKE
, vol.225
-
-
Philips, M.R.1
-
95
-
-
0031756961
-
Inhibition of K-ras-transformed rodent and human cancer cell growth via induction of apoptosis by irreversible inhibitors of Ras endoprotease
-
Chen, Y. Inhibition of K-ras-transformed rodent and human cancer cell growth via induction of apoptosis by irreversible inhibitors of Ras endoprotease. Cancer Lett. 131, 191-200 (1998).
-
(1998)
Cancer Lett.
, vol.131
, pp. 191-200
-
-
Chen, Y.1
-
96
-
-
2042544816
-
Post-translational processing of RhoA. Carboxyl methylation of the carboxyl-terminal prenylcysteine increases the half-life of Rhoa
-
Backlund, P. S. Post-translational processing of RhoA. Carboxyl methylation of the carboxyl-terminal prenylcysteine increases the half-life of Rhoa. J. Biol. Chem. 272, 33175-33180 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 33175-33180
-
-
Backlund, P.S.1
-
97
-
-
5444227865
-
Guilty as charged: B-RAF is a human oncogene
-
Garnett, M. J. & Marais, R. Guilty as charged: B-RAF is a human oncogene. Cancer Cell 6, 313-319 (2004).
-
(2004)
Cancer Cell
, vol.6
, pp. 313-319
-
-
Garnett, M.J.1
Marais, R.2
-
98
-
-
0347386407
-
Signal events: Cell signal transduction and its inhibition in cancer
-
Rowinsky, E. K. Signal events: cell signal transduction and its inhibition in cancer. Oncologist 8 (Suppl. 3), 5-17 (2003).
-
(2003)
Oncologist
, vol.8
, Issue.3 SUPPL.
, pp. 5-17
-
-
Rowinsky, E.K.1
-
99
-
-
4644370323
-
Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity
-
Reid, T. S., Terry, K. L., Casey, P. J. & Beese, L. S. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. J. Mol. Biol. 343, 417-433 (2004).
-
(2004)
J. Mol. Biol.
, vol.343
, pp. 417-433
-
-
Reid, T.S.1
Terry, K.L.2
Casey, P.J.3
Beese, L.S.4
-
100
-
-
0036280932
-
Clinical review 145: Pleiotropic effects of statins: Lipid reduction and beyond
-
McFariane, S. I., Munyappa, R., Francisco, R. & Sowers, J. R. Clinical review 145: pleiotropic effects of statins: lipid reduction and beyond. J. Clin. Endocrinol. Metab. 87, 1451-1458 (2002).
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 1451-1458
-
-
McFariane, S.I.1
Munyappa, R.2
Francisco, R.3
Sowers, J.R.4
-
101
-
-
0036382099
-
Clinical significance of pleiotropic effects of statins: Lipid reduction and beyond
-
Auer, J., Berent, R., Weber, T. & Eber, B. Clinical significance of pleiotropic effects of statins: lipid reduction and beyond. Curr. Med. Chem. 9, 1831-1850 (2002).
-
(2002)
Curr. Med. Chem.
, vol.9
, pp. 1831-1850
-
-
Auer, J.1
Berent, R.2
Weber, T.3
Eber, B.4
-
102
-
-
0037233011
-
The statins as anticancer agents
-
Chan, K. K., Oza, A. M. & Siu, L. L. The statins as anticancer agents. Clin. Cancer Res. 9, 10-19 (2003).
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 10-19
-
-
Chan, K.K.1
Oza, A.M.2
Siu, L.L.3
-
103
-
-
0028912662
-
Expression, purification, and characterization of the human squalene synthase: Use of yeast and baculoviral systems
-
Soltis, D. A. et al. Expression, purification, and characterization of the human squalene synthase: use of yeast and baculoviral systems. Arch. Biochem. Biophys. 316, 713-723 (1995).
-
(1995)
Arch. Biochem. Biophys.
, vol.316
, pp. 713-723
-
-
Soltis, D.A.1
-
104
-
-
0028088478
-
Purification and properties of geranylgeranyl-diphosphate synthase from bovine brain
-
Sagami, H., Morita, Y. & Ogura, K. Purification and properties of geranylgeranyl-diphosphate synthase from bovine brain. J. Biol. Chem. 269, 20561-20566 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 20561-20566
-
-
Sagami, H.1
Morita, Y.2
Ogura, K.3
-
105
-
-
0029007105
-
Protein farnesyltransferase: Kinetics of farnesyl pyrophosphate binding and product release
-
Furfine, E. S., Leban, J. J., Landavazo, A., Moomaw, J. F. & Casey, P. J. Protein farnesyltransferase: kinetics of farnesyl pyrophosphate binding and product release. Biochemistry 34, 6857-6862 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 6857-6862
-
-
Furfine, E.S.1
Leban, J.J.2
Landavazo, A.3
Moomaw, J.F.4
Casey, P.J.5
-
106
-
-
0035874879
-
Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors
-
Kusama, T. et al. Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. Cancer Res. 61, 4885-4891 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 4885-4891
-
-
Kusama, T.1
-
107
-
-
0442294188
-
Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation
-
Thorpe, J. L., Doitsidou, M., Ho, S. Y., Raz, E. & Farber, S. A. Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation. Dev. Cell 6, 295-302 (2004).
-
(2004)
Dev. Cell
, vol.6
, pp. 295-302
-
-
Thorpe, J.L.1
Doitsidou, M.2
Ho, S.Y.3
Raz, E.4
Farber, S.A.5
-
108
-
-
0346103657
-
Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation
-
Ye, J. et al. Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation. Proc. Natl Acad. Sci. USA 100, 15865-15870 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15865-15870
-
-
Ye, J.1
-
109
-
-
0036091925
-
Ras signalling on the endoplasmic reticulum and the Golgi
-
Chiu, V. K. et al. Ras signalling on the endoplasmic reticulum and the Golgi. Nature Cell Biol. 4, 343-350 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
, pp. 343-350
-
-
Chiu, V.K.1
-
110
-
-
0035825193
-
Differential localization of Rho GTPases in live cells: Regulation by hypervariable regions and RhoGDI binding
-
Michaelson, D. et al. Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding. J. Cell Biol. 152, 111-126 (2001).
-
(2001)
J. Cell Biol.
, vol.152
, pp. 111-126
-
-
Michaelson, D.1
-
112
-
-
1542577673
-
Rhebbing up mTOR: New insights on TSC1 and TSC2, and the pathogenesis of tuberous sclerosis
-
Kwiatkowski, D. J. Rhebbing up mTOR: new insights on TSC1 and TSC2, and the pathogenesis of tuberous sclerosis. Cancer Biol. Ther. 2, 471-476 (2003).
-
(2003)
Cancer Biol. Ther.
, vol.2
, pp. 471-476
-
-
Kwiatkowski, D.J.1
-
113
-
-
0344629830
-
PRL-3 expression in metastatic cancers
-
Bardelli, A. et al. PRL-3 expression in metastatic cancers. Clin. Cancer Res. 9, 5607-5615 (2003).
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5607-5615
-
-
Bardelli, A.1
|