-
2
-
-
0023905288
-
The primary structure and heterogeneity of tau protein from mouse brain
-
G. Lee, N. Cowan, and M. Kirschner The primary structure and heterogeneity of tau protein from mouse brain Science 239 1988 285 288 (Pubitemid 18061495)
-
(1988)
Science
, vol.239
, Issue.4837
, pp. 285-288
-
-
Lee, G.1
Cowan, N.2
Kirschner, M.3
-
3
-
-
0026001490
-
The effect of tau antisence oligonucleotides on neurite formation of cultured cerebellar macroneurons
-
A. Caceres, S. Potrebic, and K.S. Kosik The effect of tau antisence oligonucleotides on neurite formation of cultured cerebellar macroneurons J Neurosci 11 1991 1515 1523
-
(1991)
J Neurosci
, vol.11
, pp. 1515-1523
-
-
Caceres, A.1
Potrebic, S.2
Kosik, K.S.3
-
4
-
-
0028301455
-
Altered microtubule organization in small-calibre axons of mice lacking tau protein
-
DOI 10.1038/369488a0
-
A. Harada, K. Oguchi, S. Okabe, J. Kuno, S. Terada, and T. Ohshima Altered microtubule organization in small-calibre axons of mice lacking tau protein Nature 369 1994 488 491 (Pubitemid 24210568)
-
(1994)
Nature
, vol.369
, Issue.6480
, pp. 488-491
-
-
Harada, A.1
Oguchi, K.2
Okabe, S.3
Kuno, J.4
Terada, S.5
Ohshima, T.6
Sato-Yoshitake, R.7
Takei, Y.8
Noda, T.9
Hirokawa, N.10
-
5
-
-
0035067021
-
Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice
-
H.N. Dawson, A. Ferreira, M.V. Eyster, N. Ghoshal, L.I. Binder, and M.P. Vitek Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice J Cell Sci 114 2001 1179 1187 (Pubitemid 32288531)
-
(2001)
Journal of Cell Science
, vol.114
, Issue.6
, pp. 1179-1187
-
-
Dawson, H.N.1
Ferreira, A.2
Eyster, M.V.3
Ghoshal, N.4
Binder, L.I.5
Vitek, M.P.6
-
6
-
-
0034605045
-
Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes
-
Y. Takei, J. Teng, A. Harada, and N. Hirokawa Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes J Cell Biol 150 2000 989 1000
-
(2000)
J Cell Biol
, vol.150
, pp. 989-1000
-
-
Takei, Y.1
Teng, J.2
Harada, A.3
Hirokawa, N.4
-
7
-
-
0024268202
-
Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein
-
S.A. Lewis, D.H. Wang, and N.J. Cowan Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein Science 242 1988 936 939 (Pubitemid 19015256)
-
(1988)
Science
, vol.242
, Issue.4880
, pp. 936-939
-
-
Lewis, S.A.1
Wang, D.2
Cowan, N.J.3
-
8
-
-
0025959396
-
r microtubule- associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau
-
S.J. Chapin, and J.C. Bulinski Non-neuronal 210 × 10(3) Mr microtubule-associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau J Cell Sci 98 1991 27 36 (Pubitemid 21924951)
-
(1991)
Journal of Cell Science
, vol.98
, Issue.1
, pp. 27-36
-
-
Chapin, S.J.1
Bulinski, J.C.2
-
9
-
-
1842685948
-
Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (τ)
-
J.G. Wood, S.S. Mirra, N.J. Pollock, and L.I. Binder Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau) Proc Natl Acad Sci USA 83 1986 4040 4043 [Published erratum appears in Proc Natl Acad Sci U S A 1986 Dec;83(24):9773] (Pubitemid 16062418)
-
(1986)
Proceedings of the National Academy of Sciences of the United States of America
, vol.83
, Issue.11
, pp. 4040-4043
-
-
Wood, J.G.1
Mirra, S.S.2
Pollock, N.J.3
Binder, L.I.4
-
10
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
I.I. Grundke, K. Iqbal, Y.C. Tung, M. Quinlan, H.M. Wisniewski, and L.I. Binder Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology Proc Natl Acad Sci USA 83 1986 4913 4917
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 4913-4917
-
-
Grundke, I.I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
12
-
-
0032543684
-
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
-
M. Hutton, C.L. Lendon, P. Rizzu, M. Baker, S. Froelich, and H. Houlden Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 Nature 393 1998 702 705
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
-
13
-
-
0032560487
-
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
-
DOI 10.1073/pnas.95.13.7737
-
M.G. Spillantini, J.R. Murrell, M. Goedert, M.R. Farlow, A. Klug, and B. Ghetti Mutation in the tau gene in familial multiple system tauopathy with presenile dementia Proc Natl Acad Sci USA 95 1998 7737 7741 (Pubitemid 28293323)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.13
, pp. 7737-7741
-
-
Spillantini, M.G.1
Murrell, J.R.2
Goedert, M.3
Farlow, M.R.4
Klug, A.5
Ghetti, B.6
-
14
-
-
14444284106
-
Tau is a candidate gene for chromosome 17 frontotemporal dementia
-
DOI 10.1002/ana.410430617
-
P. Poorkaj, T.D. Bird, E. Wijsman, E. Nemens, R.M. Garruto, and L. Anderson Tau is a candidate gene for chromosome 17 frontotemporal dementia Ann Neurol 43 1998 815 825 (Pubitemid 28280226)
-
(1998)
Annals of Neurology
, vol.43
, Issue.6
, pp. 815-825
-
-
Poorkaj, P.1
Bird, T.D.2
Wijsman, E.3
Nemens, E.4
Garruto, R.M.5
Anderson, L.6
Andreadis, A.7
Wiederholt, W.C.8
Raskind, M.9
Schellenberg, G.D.10
-
16
-
-
45749151056
-
Animal models of Alzheimer's disease and frontotemporal dementia
-
DOI 10.1038/nrn2420, PII NRN2420
-
J. Gotz, and L.M. Ittner Animal models of Alzheimer's disease and frontotemporal dementia Nat Rev Neurosci 9 2008 532 544 (Pubitemid 351873467)
-
(2008)
Nature Reviews Neuroscience
, vol.9
, Issue.7
, pp. 532-544
-
-
Gotz, J.1
Ittner, L.M.2
-
17
-
-
56049124560
-
Knock-out and transgenic mouse models of tauopathies
-
F. Denk, and R. Wade-Martins Knock-out and transgenic mouse models of tauopathies Neurobiol Aging 30 2009 1 13
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1-13
-
-
Denk, F.1
Wade-Martins, R.2
-
18
-
-
36949014742
-
Tauopathy models and human neuropathology: Similarities and differences
-
DOI 10.1007/s00401-007-0291-9
-
S. Frank, F. Clavaguera, and M. Tolnay Tauopathy models and human neuropathology: similarities and differences Acta Neuropathol 115 2008 39 53 (Pubitemid 350238667)
-
(2008)
Acta Neuropathologica
, vol.115
, Issue.1
, pp. 39-53
-
-
Frank, S.1
Clavaguera, F.2
Tolnay, M.3
-
19
-
-
0022827447
-
Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2
-
DOI 10.1016/0169-328X(86)90033-1
-
R.L. Neve, P. Harris, K.S. Kosik, D.M. Kurnit, and T.A. Donlon Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2 Brain Res 387 1986 271 280 (Pubitemid 17220131)
-
(1986)
Molecular Brain Research
, vol.1
, Issue.3
, pp. 271-280
-
-
Neve, R.L.1
Harris, P.2
Kosik, K.S.3
-
20
-
-
0026488111
-
Structure and novel exons of the human tau gene
-
A. Andreadis, W.M. Brown, and K.S. Kosik Structure and novel exons of the human tau gene Biochemistry 31 1992 10626 10633
-
(1992)
Biochemistry
, vol.31
, pp. 10626-10633
-
-
Andreadis, A.1
Brown, W.M.2
Kosik, K.S.3
-
21
-
-
0033041179
-
Association of an extended haplotype in the tau gene with progressive supranuclear palsy
-
M. Baker, I. Litvan, H. Houlden, J. Adamson, D. Dickson, and J. Perez-Tur Association of an extended haplotype in the tau gene with progressive supranuclear palsy Hum Mol Genet 8 1999 711 715 (Pubitemid 29139987)
-
(1999)
Human Molecular Genetics
, vol.8
, Issue.4
, pp. 711-715
-
-
Baker, M.1
Litvan, I.2
Houlden, H.3
Adamson, J.4
Dickson, D.5
Perez-Tur, J.6
Hardy, J.7
Lynch, T.8
Bigio, E.9
Hutton, M.10
-
22
-
-
0024745894
-
Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease
-
M. Goedert, M.G. Spillantini, R. Jakes, D. Rutherford, and R.A. Crowther Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease Neuron 3 1989 519 526
-
(1989)
Neuron
, vol.3
, pp. 519-526
-
-
Goedert, M.1
Spillantini, M.G.2
Jakes, R.3
Rutherford, D.4
Crowther, R.A.5
-
23
-
-
0025600995
-
Expression of separate isoforms of human tau protein: Correlation with the tau pattern in brain and effects on tubulin polymerization
-
M. Goedert, and R. Jakes Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization EMBO J 9 1990 4225 4230 (Pubitemid 120025977)
-
(1990)
EMBO Journal
, vol.9
, Issue.13
, pp. 4225-4230
-
-
Goedert, M.1
Jakes, R.2
-
24
-
-
0032484089
-
Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17
-
M. Hong, V. Zhukareva, V. Vogelsberg-Ragaglia, Z. Wszolek, L. Reed, and B.I. Miller Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17 Science 282 1998 1914 1917 (Pubitemid 28555275)
-
(1998)
Science
, vol.282
, Issue.5395
, pp. 1914-1917
-
-
Hong, M.1
Zhukareva, V.2
Vogelsberg-Ragaglia, V.3
Wszolek, Z.4
Reed, L.5
Miller, B.I.6
Geschwind, D.H.7
Bird, T.D.8
McKeel, D.9
Coate, A.10
Morris, J.C.11
Wilhelmsen, K.C.12
Schellenberg, G.D.13
Trojanowski, J.Q.14
Lee, V.M.-Y.15
-
25
-
-
0024641959
-
Developmentally regulated expression of specific tau sequences
-
K.S. Kosik, L.D. Orecchio, S. Bakalis, and R.L. Neve Developmentally regulated expression of specific tau sequences Neuron 2 1989 1389 1397
-
(1989)
Neuron
, vol.2
, pp. 1389-1397
-
-
Kosik, K.S.1
Orecchio, L.D.2
Bakalis, S.3
Neve, R.L.4
-
26
-
-
0024507707
-
Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains
-
A. Himmler, D. Drechsel, M.W. Kirschner, and D.J. Martin Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains Mol Cell Biol 9 1989 1381 1388 (Pubitemid 19095177)
-
(1989)
Molecular and Cellular Biology
, vol.9
, Issue.4
, pp. 1381-1388
-
-
Himmler, A.1
Drechsel, D.2
Kirschner, M.W.3
Martin Jr., D.W.4
-
27
-
-
0029830646
-
Molecular evolution of τ protein: Implications for Alzheimer's disease
-
P.T. Nelson, K. Stefansson, J. Gulcher, and C.B. Saper Molecular evolution of tau protein: implications for Alzheimer's disease J Neurochem 67 1996 1622 1632 (Pubitemid 26314220)
-
(1996)
Journal of Neurochemistry
, vol.67
, Issue.4
, pp. 1622-1632
-
-
Nelson, P.T.1
Stefansson, K.2
Gulcher, J.3
Saper, C.B.4
-
28
-
-
0037168494
-
Molecular cloning and functional characterization of chicken brain tau: Isoforms with up to five tandem repeats
-
DOI 10.1021/bi026464m
-
H. Yoshida, and M. Goedert Molecular cloning and functional characterization of chicken brain tau: isoforms with up to five tandem repeats Biochemistry 41 2002 15203 15211 (Pubitemid 36008129)
-
(2002)
Biochemistry
, vol.41
, Issue.51
, pp. 15203-15211
-
-
Yoshida, H.1
Goedert, M.2
-
29
-
-
0029909180
-
PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans
-
M. Goedert, C.P. Baur, J. Ahringer, R. Jakes, M. Hasegawa, and M.G. Spillantini PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans J Cell Sci 109 Pt 11 1996 2661 2672 (Pubitemid 26388351)
-
(1996)
Journal of Cell Science
, vol.109
, Issue.11
, pp. 2661-2672
-
-
Goedert, M.1
Baur, C.P.2
Ahringer, J.3
Jakes, R.4
Hasegawa, M.5
Spillantini, M.G.6
Smith, M.J.7
Hill, F.8
-
30
-
-
70350507090
-
Complex splicing and neural expression of duplicated tau genes in zebrafish embryos
-
M. Chen, R.N. Martins, and M. Lardelli Complex splicing and neural expression of duplicated tau genes in zebrafish embryos J Alzheimers Dis 18 2009 305 317
-
(2009)
J Alzheimers Dis
, vol.18
, pp. 305-317
-
-
Chen, M.1
Martins, R.N.2
Lardelli, M.3
-
31
-
-
0037160522
-
Molecular cloning of XTP, a tau-like microtubule-associated protein from Xenopus laevis tadpoles
-
DOI 10.1016/S0378-1119(01)00869-1, PII S0378111901008691
-
O.F. Olesen, H. Kawabata-Fukui, K. Yoshizato, and N. Noro Molecular cloning of XTP, a tau-like microtubule-associated protein from Xenopus laevis tadpoles Gene 283 2002 299 309 (Pubitemid 34178534)
-
(2002)
Gene
, vol.283
, Issue.1-2
, pp. 299-309
-
-
Olesen, O.F.1
Kawabata-Fukui, H.2
Yoshizato, K.3
Noro, N.4
-
32
-
-
0028175215
-
Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau
-
B.L. Goode, and S.C. Feinstein Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau J Cell Biol 124 1994 769 782
-
(1994)
J Cell Biol
, vol.124
, pp. 769-782
-
-
Goode, B.L.1
Feinstein, S.C.2
-
33
-
-
0028820411
-
Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules
-
B. Trinczek, J. Biernat, K. Baumann, E.M. Mandelkow, and E. Mandelkow Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules Mol Biol Cell 6 1995 1887 1902
-
(1995)
Mol Biol Cell
, vol.6
, pp. 1887-1902
-
-
Trinczek, B.1
Biernat, J.2
Baumann, K.3
Mandelkow, E.M.4
Mandelkow, E.5
-
34
-
-
34249706348
-
The "jaws" of the tau-microtubule interaction
-
M.D. Mukrasch, M. von Bergen, J. Biernat, D. Fischer, C. Griesinger, and E. Mandelkow The "jaws" of the tau-microtubule interaction J Biol Chem 282 2007 12230 12239
-
(2007)
J Biol Chem
, vol.282
, pp. 12230-12239
-
-
Mukrasch, M.D.1
Von Bergen, M.2
Biernat, J.3
Fischer, D.4
Griesinger, C.5
Mandelkow, E.6
-
35
-
-
0021338217
-
Phosphorylation affects the ability of tau protein to promote microtubule assembly
-
G. Lindwall, and R.D. Cole Phosphorylation affects the ability of tau protein to promote microtubule assembly J Biol Chem 259 1984 5301 5305 (Pubitemid 14140641)
-
(1984)
Journal of Biological Chemistry
, vol.259
, Issue.8
, pp. 5301-5305
-
-
Lindwall, G.1
Cole, R.D.2
-
36
-
-
0027370141
-
In vivo phosphorylation sites in fetal and adult rat tau
-
A. Watanabe, M. Hasegawa, M. Suzuki, K. Takio, M. Morishima-Kawashima, and K. Titani In vivo phosphorylation sites in fetal and adult rat tau J Biol Chem 268 1993 25712 25717 (Pubitemid 23358184)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.34
, pp. 25712-25717
-
-
Watanabe, A.1
Hasegawa, M.2
Suzuki, M.3
Takio, K.4
Morishima-Kawashima, M.5
Titani, K.6
Arai, T.7
Kosik, K.S.8
Ihara, Y.9
-
37
-
-
3042641844
-
Gem GTPase and Tau: Morphological changes induced by Gem GTpase in CHO cells are antagonized by tau
-
DOI 10.1074/jbc.M401634200
-
F. Oyama, S. Kotliarova, A. Harada, M. Ito, H. Miyazaki, and Y. Ueyama Gem GTPase and tau: morphological changes induced by gem GTPase in cho cells are antagonized by tau J Biol Chem 279 2004 27272 27277 (Pubitemid 38812566)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.26
, pp. 27272-27277
-
-
Oyama, F.1
Kotliarova, S.2
Harada, A.3
Ito, M.4
Miyazaki, H.5
Ueyama, Y.6
Hirokawa, N.7
Nukina, N.8
Ihara, Y.9
-
38
-
-
0033969771
-
Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice
-
DOI 10.1016/S0304-3940(99)00964-7, PII S0304394099009647
-
S. Ikegami, A. Harada, and N. Hirokawa Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice Neurosci Lett 279 2000 129 132 (Pubitemid 30069810)
-
(2000)
Neuroscience Letters
, vol.279
, Issue.3
, pp. 129-132
-
-
Ikegami, S.1
Harada, A.2
Hirokawa, N.3
-
39
-
-
34248181511
-
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
-
DOI 10.1126/science.1141736
-
E.D. Roberson, K. Scearce-Levie, J.J. Palop, F. Yan, I.H. Cheng, and T. Wu Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model Science 316 2007 750 754 (Pubitemid 46717684)
-
(2007)
Science
, vol.316
, Issue.5825
, pp. 750-754
-
-
Roberson, E.D.1
Scearce-Levie, K.2
Palop, J.J.3
Yan, F.4
Cheng, I.H.5
Wu, T.6
Gerstein, H.7
Yu, G.-Q.8
Mucke, L.9
-
40
-
-
0029843684
-
τ is widely expressed in rat tissues
-
Y. Gu, F. Oyama, and Y. Ihara τ is widely expressed in rat tissues J Neurochem 76 1996 1235 1244
-
(1996)
J Neurochem
, vol.76
, pp. 1235-1244
-
-
Gu, Y.1
Oyama, F.2
Ihara, Y.3
-
41
-
-
0028136116
-
Expression of three- and four-repeat tau isoforms in mouse liver
-
L. Kenner, Y. El-Shabrawi, H. Hutter, M. Forstner, K. Zatloukal, and G. Hoefler Expression of three- and four-repeat tau isoforms in mouse liver Hepatology 20 1994 1086 1089 (Pubitemid 24296520)
-
(1994)
Hepatology
, vol.20
, Issue.4
, pp. 1086-1089
-
-
Kenner, L.1
El-Shabrawi, Y.2
Hutter, H.3
Forstner, M.4
Zatloukal, K.5
Hoefler, G.6
Preisegger, K.-H.7
Kurzbauer, R.8
Denk, H.9
-
42
-
-
0031823710
-
Estramustine resistance correlates with tau over-expression in human prostatic carcinoma cells
-
DOI 10.1002/(SICI)1097-0215(19980812)77:4<626::AID-IJC24>3.0.CO;2-2
-
S. Sangrajrang, P. Denoulet, G. Millot, R. Tatoud, M.P. Podgorniak, and K.D. Tew Estramustine resistance correlates with tau over-expression in human prostatic carcinoma cells Int J Cancer 77 1998 626 631 (Pubitemid 28340913)
-
(1998)
International Journal of Cancer
, vol.77
, Issue.4
, pp. 626-631
-
-
Sangrajrang, S.1
Denoulet, P.2
Millot, G.3
Tatoud, R.4
Podgorniak, M.-P.5
Tew, K.D.6
Calvo, F.7
Fellous, A.8
-
43
-
-
70350180734
-
Microtubule-associated protein tau in human prostate cancer cells: Isoforms, phosphorylation, and interactions
-
S. Souter, and G. Lee Microtubule-associated protein tau in human prostate cancer cells: Isoforms, phosphorylation, and interactions J Cell Biochem 108 2009 555 564
-
(2009)
J Cell Biochem
, vol.108
, pp. 555-564
-
-
Souter, S.1
Lee, G.2
-
44
-
-
20444388706
-
Microtubule-associated protein tau: A marker of paclitaxel sensitivity in breast cancer
-
DOI 10.1073/pnas.0408974102
-
R. Rouzier, R. Rajan, P. Wagner, K.R. Hess, D.L. Gold, and J. Stec Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer Proc Natl Acad Sci USA 102 2005 8315 8320 (Pubitemid 40800086)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.23
, pp. 8315-8320
-
-
Rouzier, R.1
Rajan, R.2
Wagner, P.3
Hess, K.R.4
Gold, D.L.5
Stec, J.6
Ayers, M.7
Ross, J.S.8
Zhang, P.9
Buchholz, T.A.10
Kuerer, H.11
Green, M.12
Arun, B.13
Hortobagyi, G.N.14
Symmans, W.F.15
Pusztai, L.16
-
45
-
-
33745063686
-
Reduced tau expression in gastric cancer can identify candidates for successful Paclitaxel treatment
-
DOI 10.1038/sj.bjc.6603182, PII 6603182
-
K. Mimori, N. Sadanaga, Y. Yoshikawa, K. Ishikawa, M. Hashimoto, and F. Tanaka Reduced tau expression in gastric cancer can identify candidates for successful Paclitaxel treatment Br J Cancer 94 2006 1894 1897 (Pubitemid 43882581)
-
(2006)
British Journal of Cancer
, vol.94
, Issue.12
, pp. 1894-1897
-
-
Mimori, K.1
Sadanaga, N.2
Yoshikawa, Y.3
Ishikawa, K.4
Hashimoto, M.5
Tanaka, F.6
Sasaki, A.7
Inoue, H.8
Sugimachi, K.9
Mori, M.10
-
46
-
-
34250705854
-
Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer
-
DOI 10.1158/1535-7163.MCT-06-0592
-
A. Jimeno, G. Hallur, A. Chan, X. Zhang, G. Cusatis, and F. Chan Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer Mol Cancer Ther 6 2007 1509 1516 (Pubitemid 46954017)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.5
, pp. 1509-1516
-
-
Jimeno, A.1
Hallur, G.2
Chan, A.3
Zhang, X.4
Cusatis, G.5
Chan, F.6
Shah, P.7
Chen, R.8
Hamel, E.9
Garrett-Mayer, E.10
Khan, S.11
Hidalgo, M.12
-
47
-
-
0028246491
-
Twisted tubulofilaments of inclusion body myositis muscle resemble paired helical filaments of Alzheimer brain and contain hyperphosphorylated tau
-
V. Askanas, W.K. Engel, M. Bilak, R.B. Alvarez, and D.J. Selkoe Twisted tubulofilaments of inclusion body myositis muscle resemble paired helical filaments of Alzheimer brain and contain hyperphosphorylated tau Am J Pathol 144 1994 177 187 (Pubitemid 24158371)
-
(1994)
American Journal of Pathology
, vol.144
, Issue.1
, pp. 177-187
-
-
Askanas, V.1
Engel, W.K.2
Bilak, M.3
Alvarez, R.B.4
Selkoe, D.J.5
-
48
-
-
34548036227
-
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
-
DOI 10.1038/nrn2194, PII NRN2194
-
C. Ballatore, V.M. Lee, and J.Q. Trojanowski Tau-mediated neurodegeneration in Alzheimer's disease and related disorders Nat Rev Neurosci 8 2007 663 672 (Pubitemid 47283144)
-
(2007)
Nature Reviews Neuroscience
, vol.8
, Issue.9
, pp. 663-672
-
-
Ballatore, C.1
Lee, V.M.-Y.2
Trojanowski, J.Q.3
-
49
-
-
34249862316
-
The role of tau phosphorylation and cleavage in neuronal cell death
-
DOI 10.2741/2097
-
W. Chun, and G.V. Johnson The role of tau phosphorylation and cleavage in neuronal cell death Front Biosci 12 2007 733 756 (Pubitemid 46860209)
-
(2007)
Frontiers in Bioscience
, vol.12
, Issue.2
, pp. 733-756
-
-
Chun, W.1
Johnson, G.V.W.2
-
50
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
J. Hardy, and D.J. Selkoe The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science 297 2002 353 356 (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
51
-
-
0037197836
-
Tau is essential to β-amyloid-induced neurotoxicity
-
DOI 10.1073/pnas.092136199
-
M. Rapoport, H.N. Dawson, L.I. Binder, M.P. Vitek, and A. Ferreira Tau is essential to beta -amyloid-induced neurotoxicity Proc Natl Acad Sci USA 99 2002 6364 6369 (Pubitemid 34493317)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.9
, pp. 6364-6369
-
-
Rapoport, M.1
Dawson, H.N.2
Binder, L.I.3
Vitek, M.P.4
Ferreira, A.5
-
52
-
-
0842281547
-
Tau protein and neurodegeneration
-
DOI 10.1016/j.semcdb.2003.12.015
-
M. Goedert Tau protein and neurodegeneration Semin Cell Dev Biol 15 2004 45 49 (Pubitemid 38177367)
-
(2004)
Seminars in Cell and Developmental Biology
, vol.15
, Issue.1
, pp. 45-49
-
-
Goedert, M.1
-
53
-
-
0142139311
-
Tau Protein in Familial and Sporadic Diseases
-
DOI 10.1385/NMM:4:1-2:37
-
D. Yancopoulou, and M.G. Spillantini Tau protein in familial and sporadic diseases Neuromolecular Med 4 2003 37 48 (Pubitemid 37315184)
-
(2003)
NeuroMolecular Medicine
, vol.4
, Issue.1-2
, pp. 37-48
-
-
Yancopoulou, D.1
Spillantini, M.G.2
-
54
-
-
77449136474
-
Neuropathology of non-Alzheimer degenerative disorders
-
D.W. Dickson Neuropathology of non-Alzheimer degenerative disorders Int J Clin Exp Pathol 3 2009 1 23
-
(2009)
Int J Clin Exp Pathol
, vol.3
, pp. 1-23
-
-
Dickson, D.W.1
-
55
-
-
60049091402
-
Tauopathies with parkinsonism: Clinical spectrum, neuropathologic basis, biological markers, and treatment options
-
A.C. Ludolph, J. Kassubek, B.G. Landwehrmeyer, E. Mandelkow, E.M. Mandelkow, and D.J. Burn Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options Eur J Neurol 16 2009 297 309
-
(2009)
Eur J Neurol
, vol.16
, pp. 297-309
-
-
Ludolph, A.C.1
Kassubek, J.2
Landwehrmeyer, B.G.3
Mandelkow, E.4
Mandelkow, E.M.5
Burn, D.J.6
-
56
-
-
65249116483
-
Tau mutations in neurodegenerative diseases
-
M.S. Wolfe Tau mutations in neurodegenerative diseases J Biol Chem 284 2009 6021 6025
-
(2009)
J Biol Chem
, vol.284
, pp. 6021-6025
-
-
Wolfe, M.S.1
-
57
-
-
33847194237
-
Hereditary frontotemporal dementia caused by Tau gene mutations
-
J. van Swieten, and M.G. Spillantini Hereditary frontotemporal dementia caused by Tau gene mutations Brain Pathol 17 2007 63 73
-
(2007)
Brain Pathol
, vol.17
, pp. 63-73
-
-
Van Swieten, J.1
Spillantini, M.G.2
-
59
-
-
0033591225
-
5′ splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10
-
A. Grover, H. Houlden, M. Baker, J. Adamson, J. Lewis, and G. Prihar 5′ splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10 J Biol Chem 274 1999 15134 15143
-
(1999)
J Biol Chem
, vol.274
, pp. 15134-15143
-
-
Grover, A.1
Houlden, H.2
Baker, M.3
Adamson, J.4
Lewis, J.5
Prihar, G.6
-
60
-
-
33847178181
-
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
-
A.J. Myers, A.M. Pittman, A.S. Zhao, K. Rohrer, M. Kaleem, and L. Marlowe The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts Neurobiol Dis 25 2007 561 570
-
(2007)
Neurobiol Dis
, vol.25
, pp. 561-570
-
-
Myers, A.J.1
Pittman, A.M.2
Zhao, A.S.3
Rohrer, K.4
Kaleem, M.5
Marlowe, L.6
-
61
-
-
33847199377
-
A decade of tau transgenic animal models and beyond
-
J. Gotz, N. Deters, A. Doldissen, L. Bokhari, Y. Ke, and A. Wiesner A decade of tau transgenic animal models and beyond Brain Pathol 17 2007 91 103
-
(2007)
Brain Pathol
, vol.17
, pp. 91-103
-
-
Gotz, J.1
Deters, N.2
Doldissen, A.3
Bokhari, L.4
Ke, Y.5
Wiesner, A.6
-
62
-
-
33646126924
-
A decade of modeling Alzheimer's disease in transgenic mice
-
E. McGowan, J. Eriksen, and M. Hutton A decade of modeling Alzheimer's disease in transgenic mice Trends Genet 22 2006 281 289
-
(2006)
Trends Genet
, vol.22
, pp. 281-289
-
-
McGowan, E.1
Eriksen, J.2
Hutton, M.3
-
63
-
-
0042697305
-
Triple-transgenic model of Alzheimer's Disease with plaques and tangles: Intracellular Aβ and synaptic dysfunction
-
DOI 10.1016/S0896-6273(03)00434-3
-
S. Oddo, A. Caccamo, J.D. Shepherd, M.P. Murphy, T.E. Golde, and R. Kayed Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction Neuron 39 2003 409 421 (Pubitemid 36937044)
-
(2003)
Neuron
, vol.39
, Issue.3
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
64
-
-
0141960033
-
β-amyloid induces paired helical filament-like tau filaments in tissue culture
-
DOI 10.1074/jbc.M308243200
-
A. Ferrari, F. Hoerndli, T. Baechi, R.M. Nitsch, and J. Gotz beta-Amyloid induces paired helical filament-like tau filaments in tissue culture J Biol Chem 278 2003 40162 40168 (Pubitemid 37248584)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.41
, pp. 40162-40168
-
-
Ferrari, A.1
Hoerndli, F.2
Baechi, T.3
Nitsch, R.M.4
Gotz, J.5
-
65
-
-
0036841609
-
Tau Assembly in inducible transfectants expressing wild-type or FTDP-17 tau
-
M. DeTure, L.W. Ko, C. Easson, and S.H. Yen Tau assembly in inducible transfectants expressing wild-type or FTDP-17 tau Am J Pathol 161 2002 1711 1722 (Pubitemid 35265530)
-
(2002)
American Journal of Pathology
, vol.161
, Issue.5
, pp. 1711-1722
-
-
DeTure, M.1
Ko, L.-W.2
Easson, C.3
Yen, S.-H.4
-
66
-
-
10944258455
-
Tau aggregation is driven by a transition from random coil to beta sheet structure
-
DOI 10.1016/j.bbadis.2004.09.010, PII S0925443904001802
-
M. von Bergen, S. Barghorn, J. Biernat, E.M. Mandelkow, and E. Mandelkow Tau aggregation is driven by a transition from random coil to beta sheet structure Biochim Biophys Acta 1739 2005 158 166 (Pubitemid 40018535)
-
(2005)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1739
, Issue.2
, pp. 158-166
-
-
Von Bergen, M.1
Barghorn, S.2
Biernat, J.3
Mandelkow, E.-M.4
Mandelkow, E.5
-
67
-
-
10944248857
-
Tau, tangles, and Alzheimer's disease
-
DOI 10.1016/j.bbadis.2004.08.014, PII S0925443904001619
-
L.I. Binder, A.L. Guillozet-Bongaarts, F. Garcia-Sierra, and R.W. Berry Tau, tangles, and Alzheimer's disease Biochim Biophys Acta 1739 2005 216 223 (Pubitemid 40018540)
-
(2005)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1739
, Issue.2
, pp. 216-223
-
-
Binder, L.I.1
Guillozet-Bongaarts, A.L.2
Garcia-Sierra, F.3
Berry, R.W.4
-
68
-
-
0347594304
-
Modeling Tau Polymerization in Vitro: A Review and Synthesis
-
DOI 10.1021/bi035722s
-
T.C. Gamblin, R.W. Berry, and L.I. Binder Modeling tau polymerization in vitro: a review and synthesis Biochemistry 42 2003 15009 15017 (Pubitemid 38031698)
-
(2003)
Biochemistry
, vol.42
, Issue.51
, pp. 15009-15017
-
-
Gamblin, T.C.1
Berry, R.W.2
Binder, L.I.3
-
70
-
-
0041689948
-
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
DOI 10.1073/pnas.1630428100
-
T.C. Gamblin, F. Chen, A. Zambrano, A. Abraha, S. Lagalwar, and A.L. Guillozet Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease Proc Natl Acad Sci USA 100 2003 10032 10037 (Pubitemid 37087063)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.17
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
LaPointe, N.10
Miller, R.11
Berry, R.W.12
Binder, L.I.13
Cryns, V.L.14
-
71
-
-
0034705192
-
In vitro polymerization of tau protein monitored by laser light scattering: Method and application to the study of FTDP-17 mutants
-
DOI 10.1021/bi000201f
-
T.C. Gamblin, M.E. King, H. Dawson, M.P. Vitek, J. Kuret, and R.W. Berry In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants Biochemistry 39 2000 6136 6144 (Pubitemid 30327089)
-
(2000)
Biochemistry
, vol.39
, Issue.20
, pp. 6136-6144
-
-
Gamblin, T.C.1
King, M.E.2
Dawson, H.3
Vitek, M.P.4
Kuret, J.5
Berry, R.W.6
Binder, L.I.7
-
72
-
-
0035930625
-
Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure
-
M. von Bergen, S. Barghorn, L. Li, A. Marx, J. Biernat, and E.M. Mandelkow Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure J Biol Chem 276 2001 48165 48174
-
(2001)
J Biol Chem
, vol.276
, pp. 48165-48174
-
-
Von Bergen, M.1
Barghorn, S.2
Li, L.3
Marx, A.4
Biernat, J.5
Mandelkow, E.M.6
-
73
-
-
0035425347
-
Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein
-
DOI 10.1042/0264-6021:3570759
-
J. Eidenmuller, T. Fath, T. Maas, M. Pool, E. Sontag, and R. Brandt Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein Biochem J 357 2001 759 767 (Pubitemid 32735156)
-
(2001)
Biochemical Journal
, vol.357
, Issue.3
, pp. 759-767
-
-
Eidenmuller, J.1
Fath, T.2
Maas, T.3
Pool, M.4
Sontag, E.5
Brandt, R.6
-
74
-
-
0033596946
-
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
-
A. Schneider, J. Biernat, M. von Bergen, E. Mandelkow, and E.M. Mandelkow Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments Biochemistry 38 1999 3549 3558
-
(1999)
Biochemistry
, vol.38
, pp. 3549-3558
-
-
Schneider, A.1
Biernat, J.2
Von Bergen, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
75
-
-
67649622427
-
Pseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization
-
Q. Sun, and T.C. Gamblin Pseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization Biochemistry 48 2009 6002 6011
-
(2009)
Biochemistry
, vol.48
, pp. 6002-6011
-
-
Sun, Q.1
Gamblin, T.C.2
-
76
-
-
9644273963
-
Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro
-
DOI 10.1074/jbc.M405527200
-
M. Necula, and J. Kuret Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro J Biol Chem 279 2004 49694 49703 (Pubitemid 39577773)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.48
, pp. 49694-49703
-
-
Necula, M.1
Kuret, J.2
-
77
-
-
22344438508
-
Medicine: Tau suppression in a neurodegenerative mouse model improves memory function
-
DOI 10.1126/science.1113694
-
K. SantaCruz, J. Lewis, T. Spires, J. Paulson, L. Kotilinek, and M. Ingelsson Tau suppression in a neurodegenerative mouse model improves memory function Science 309 2005 476 481 (Pubitemid 40994688)
-
(2005)
Science
, vol.309
, Issue.5733
, pp. 476-481
-
-
Santacruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McCowan, E.10
Forster, C.11
Yue, M.12
Orne, J.13
Janus, C.14
Mariash, A.15
Kuskowski, M.16
Hyman, B.17
Hutton, M.18
Ashe, K.H.19
-
78
-
-
37149046340
-
Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau
-
DOI 10.1038/sj.emboj.7601917, PII 7601917
-
T. Kimura, S. Yamashita, T. Fukuda, J.M. Park, M. Murayama, and T. Mizoroki Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau EMBO J 26 2007 5143 5152 (Pubitemid 350261280)
-
(2007)
EMBO Journal
, vol.26
, Issue.24
, pp. 5143-5152
-
-
Kimura, T.1
Yamashita, S.2
Fukuda, T.3
Park, J.-M.4
Murayama, M.5
Mizoroki, T.6
Yoshiike, Y.7
Sahara, N.8
Takashima, A.9
-
79
-
-
26844479213
-
Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation
-
DOI 10.1016/j.febslet.2005.09.047, PII S0014579305011683
-
T. Taniguchi, N. Doe, S. Matsuyama, Y. Kitamura, H. Mori, and N. Saito Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation FEBS Lett 579 2005 5704 5712 (Pubitemid 41460490)
-
(2005)
FEBS Letters
, vol.579
, Issue.25
, pp. 5704-5712
-
-
Taniguchi, T.1
Doe, N.2
Matsuyama, S.3
Kitamura, Y.4
Mori, H.5
Saito, N.6
Tanaka, C.7
-
80
-
-
0035958642
-
Tauopathy in Drosophila: Neurodegeneration without neurofibrillary tangles
-
C.W. Wittmann, M.F. Wszolek, J.M. Shulman, P.M. Salvaterra, J. Lewis, and M. Hutton Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles Science 293 2001 711 714 (Pubitemid 32728676)
-
(2001)
Science
, vol.293
, Issue.5530
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
81
-
-
0042889049
-
Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy
-
DOI 10.1073/pnas.1533448100
-
B.C. Kraemer, B. Zhang, J.B. Leverenz, J.H. Thomas, J.Q. Trojanowski, and G.D. Schellenberg Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy Proc Natl Acad Sci USA 100 2003 9980 9985 (Pubitemid 37087054)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.17
, pp. 9980-9985
-
-
Kraemer, B.C.1
Zhang, B.2
Leverenz, J.B.3
Thomas, J.H.4
Trojanowski, J.Q.5
Schellenberg, G.D.6
-
82
-
-
58049214009
-
Tau oligomerization: A role for tau aggregation intermediates linked to neurodegeneration
-
N. Sahara, S. Maeda, and A. Takashima Tau oligomerization: a role for tau aggregation intermediates linked to neurodegeneration Curr Alzheimer Res 5 2008 591 598
-
(2008)
Curr Alzheimer Res
, vol.5
, pp. 591-598
-
-
Sahara, N.1
Maeda, S.2
Takashima, A.3
-
83
-
-
67349142329
-
Mechanisms of tau-induced neurodegeneration
-
K. Iqbal, F. Liu, C.X. Gong, C. Alonso Adel, and I. Grundke-Iqbal Mechanisms of tau-induced neurodegeneration Acta Neuropathol 118 2009 53 69
-
(2009)
Acta Neuropathol
, vol.118
, pp. 53-69
-
-
Iqbal, K.1
Liu, F.2
Gong, C.X.3
Alonso Adel, C.4
Grundke-Iqbal, I.5
-
84
-
-
49149098525
-
Tau aggregates: Toxic, inert, or protective species?
-
A. Bretteville, and E. Planel Tau aggregates: toxic, inert, or protective species? J Alzheimers Dis 14 2008 431 436
-
(2008)
J Alzheimers Dis
, vol.14
, pp. 431-436
-
-
Bretteville, A.1
Planel, E.2
-
85
-
-
17044435830
-
Tau phosphorylation in Alzheimer's disease: Pathogen or protector?
-
H.G. Lee, G. Perry, P.I. Moreira, M.R. Garrett, Q. Liu, and X. Zhu Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends Mol Med 11 2005 164 169
-
(2005)
Trends Mol Med
, vol.11
, pp. 164-169
-
-
Lee, H.G.1
Perry, G.2
Moreira, P.I.3
Garrett, M.R.4
Liu, Q.5
Zhu, X.6
-
87
-
-
0026711059
-
Fetal-type phosphorylation of the tau in paired helical filaments
-
K. Kanemaru, K. Takio, R. Miura, K. Titani, and Y. Ihara Fetal-type phosphorylation of the tau in paired helical filaments J Neurochem 58 1992 1667 1675
-
(1992)
J Neurochem
, vol.58
, pp. 1667-1675
-
-
Kanemaru, K.1
Takio, K.2
Miura, R.3
Titani, K.4
Ihara, Y.5
-
88
-
-
0027429479
-
Developmental changes in τ phosphorylation: Fetal τ is transiently phosphorylated in a manner similar to paired helical filament-τ characteristic of Alzheimer's disease
-
DOI 10.1111/j.1471-4159.1993.tb07444.x
-
J.P. Brion, C. Smith, A.M. Couck, J.M. Gallo, and B.H. Anderton Developmental changes in tau phosphorylation: fetal tau is transiently phosphorylated in a manner similar to paired helical filament-tau characteristic of Alzheimer's disease J Neurochem 61 1993 2071 2080 (Pubitemid 23354063)
-
(1993)
Journal of Neurochemistry
, vol.61
, Issue.6
, pp. 2071-2080
-
-
Brion, J.-P.1
Smith, C.2
Couck, A.-M.3
Gallo, J.-M.4
Anderton, B.H.5
-
89
-
-
70349638299
-
Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies
-
K.R. Brunden, J.Q. Trojanowski, and V.M. Lee Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies Nat Rev Drug Discov 8 2009 783 793
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 783-793
-
-
Brunden, K.R.1
Trojanowski, J.Q.2
Lee, V.M.3
-
90
-
-
55249086251
-
Hyperphosphorylation of microtubule-associated protein tau: A promising therapeutic target for Alzheimer disease
-
C.X. Gong, and K. Iqbal Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease Curr Med Chem 15 2008 2321 2328
-
(2008)
Curr Med Chem
, vol.15
, pp. 2321-2328
-
-
Gong, C.X.1
Iqbal, K.2
-
91
-
-
77956056008
-
Animal models reveal role for tau phosphorylation in human disease
-
J. Gotz, A. Gladbach, L. Pennanen, J. van Eersel, A. Schild, and D. David Animal models reveal role for tau phosphorylation in human disease Biochim Biophys Acta 1802 2010 860 871
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 860-871
-
-
Gotz, J.1
Gladbach, A.2
Pennanen, L.3
Van Eersel, J.4
Schild, A.5
David, D.6
-
92
-
-
21044449225
-
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
-
DOI 10.1073/pnas.0500466102
-
W. Noble, E. Planel, C. Zehr, V. Olm, J. Meyerson, and F. Suleman Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo Proc Natl Acad Sci USA 102 2005 6990 6995 (Pubitemid 40675429)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.19
, pp. 6990-6995
-
-
Noble, W.1
Planel, E.2
Zehr, C.3
Olm, V.4
Meyerson, J.5
Suleman, F.6
Gaynor, K.7
Wang, L.8
LaFrancois, J.9
Feinstein, B.10
Burns, M.11
Krishnamurthy, P.12
Wen, Y.13
Bhat, R.14
Lewis, J.15
Dickson, D.16
Duff, K.17
-
93
-
-
31944434543
-
TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model
-
DOI 10.1016/j.cub.2005.12.042, PII S0960982206010256
-
V. Khurana, Y. Lu, M.L. Steinhilb, S. Oldham, J.M. Shulman, and M.B. Feany TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model Curr Biol 16 2006 230 241 (Pubitemid 43190222)
-
(2006)
Current Biology
, vol.16
, Issue.3
, pp. 230-241
-
-
Khurana, V.1
Lu, Y.2
Steinhilb, M.L.3
Oldham, S.4
Shulman, J.M.5
Feany, M.B.6
-
94
-
-
33947289969
-
Cell division in the CNS: Protective response or lethal event in post-mitotic neurons?
-
DOI 10.1016/j.bbadis.2006.10.002, PII S0925443906001992
-
Y. Yang, and K. Herrup Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim Biophys Acta 1772 2007 457 466 (Pubitemid 46420409)
-
(2007)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1772
, Issue.4
, pp. 457-466
-
-
Yang, Y.1
Herrup, K.2
-
95
-
-
60649083945
-
Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease
-
H.G. Lee, G. Casadesus, X. Zhu, R.J. Castellani, A. McShea, and G. Perry Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease Neurochem Int 54 2009 84 88
-
(2009)
Neurochem Int
, vol.54
, pp. 84-88
-
-
Lee, H.G.1
Casadesus, G.2
Zhu, X.3
Castellani, R.J.4
McShea, A.5
Perry, G.6
-
96
-
-
0030062245
-
Mitotic mechanisms in Alzheimer's disease?
-
DOI 10.1083/jcb.132.3.413
-
I. Vincent, M. Rosado, and P. Davies Mitotic mechanisms in Alzheimer's disease? J Cell Biol 132 1996 413 425 (Pubitemid 26053445)
-
(1996)
Journal of Cell Biology
, vol.132
, Issue.3
, pp. 413-425
-
-
Vincent, I.1
Rosado, M.2
Davies, P.3
-
97
-
-
0031928259
-
Mitotic phosphorylation of tau protein in neuronal cell lines resembles phosphorylation in Alzheimer's disease
-
U. Preuss, and E.M. Mandelkow Mitotic phosphorylation of tau protein in neuronal cell lines resembles phosphorylation in Alzheimer's disease Eur J Cell Biol 76 1998 176 184 (Pubitemid 28365356)
-
(1998)
European Journal of Cell Biology
, vol.76
, Issue.3
, pp. 176-184
-
-
Preuss, U.1
Mandelkow, E.-M.2
-
98
-
-
17044461433
-
The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: Implications for Alzheimer's disease
-
S. Illenberger, Q. Zheng-Fischhofer, U. Preuss, K. Stamer, K. Baumann, and B. Trinczek The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease Mol Biol Cell 9 1998 1495 1512 (Pubitemid 28303492)
-
(1998)
Molecular Biology of the Cell
, vol.9
, Issue.6
, pp. 1495-1512
-
-
Illenberger, S.1
Zheng-Fischhofer, Q.2
Preuss, U.3
Stamer, K.4
Baumann, K.5
Trinczek, B.6
Biernat, J.7
Godemann, R.8
Mandelkow, E.-M.9
Mandelkow, E.10
-
99
-
-
18644369888
-
Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis
-
DOI 10.1046/j.1471-4159.2002.01143.x
-
P. Delobel, S. Flament, M. Hamdane, C. Mailliot, A.V. Sambo, and S. Begard Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis J Neurochem 83 2002 412 420 (Pubitemid 35191406)
-
(2002)
Journal of Neurochemistry
, vol.83
, Issue.2
, pp. 412-420
-
-
Delobel, P.1
Flament, S.2
Hamdane, M.3
Mailliot, C.4
Sambo, A.-V.5
Begard, S.6
Sergeant, N.7
Delacourte, A.8
Vilain, J.-P.9
Buee, L.10
-
100
-
-
0035871660
-
DNA replication precedes neuronal cell death in Alzheimer's disease
-
Y. Yang, D.S. Geldmacher, and K. Herrup DNA replication precedes neuronal cell death in Alzheimer's disease J Neurosci 21 2001 2661 2668 (Pubitemid 32298208)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.8
, pp. 2661-2668
-
-
Yang, Y.1
Geldmacher, D.S.2
Herrup, K.3
-
101
-
-
0027058857
-
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau
-
D.N. Drechsel, A.A. Hyman, M.H. Cobb, and M.W. Kirschner Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau Mol Biol Cell 3 1992 1141 1154 (Pubitemid 23088964)
-
(1992)
Molecular Biology of the Cell
, vol.3
, Issue.10
, pp. 1141-1154
-
-
Drechsel, D.N.1
Hyman, A.A.2
Cobb, M.H.3
Kirschner, M.W.4
-
102
-
-
0026704256
-
Expression of tau protein in non-neuronal cells: Microtubule binding and stabilization
-
G. Lee, and S.L. Rook Expression of tau protein in non-neuronal cells: microtubule binding and stabilization J Cell Sci 102 Pt 2 1992 227 237
-
(1992)
J Cell Sci
, vol.102
, Issue.PART 2
, pp. 227-237
-
-
Lee, G.1
Rook, S.L.2
-
103
-
-
0027406644
-
Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro
-
R. Brandt, and G. Lee Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro J Biol Chem 268 1993 3414 3419 (Pubitemid 23070977)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.5
, pp. 3414-3419
-
-
Brandt, R.1
Lee, G.2
-
104
-
-
0028027088
-
Domains of τ protein and interactions with microtubules
-
N. Gustke, B. Trinczek, J. Biernat, E.M. Mandelkow, and E. Mandelkow Domains of tau protein and interactions with microtubules Biochemistry 33 1994 9511 9522 (Pubitemid 24272907)
-
(1994)
Biochemistry
, vol.33
, Issue.32
, pp. 9511-9522
-
-
Gustke, N.1
Trinczek, B.2
Biernat, J.3
Mandelkow, E.-M.4
Mandelkow, E.5
-
105
-
-
0031035402
-
Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly
-
B.L. Goode, P.E. Denis, D. Panda, M.J. Radeke, H.P. Miller, and L. Wilson Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly Mol Biol Cell 8 1997 353 365 (Pubitemid 27097949)
-
(1997)
Molecular Biology of the Cell
, vol.8
, Issue.2
, pp. 353-365
-
-
Goode, B.L.1
Denis, P.E.2
Panda, D.3
Radeke, M.J.4
Miller, H.P.5
Wilson, L.6
Feinstein, S.C.7
-
106
-
-
21644446496
-
Sites of tau important for aggregation populate β-structure and bind to microtubules and polyanions
-
DOI 10.1074/jbc.M501565200
-
M.D. Mukrasch, J. Biernat, M. von Bergen, C. Griesinger, E. Mandelkow, and M. Zweckstetter Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions J Biol Chem 280 2005 24978 24986 (Pubitemid 40934590)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.26
, pp. 24978-24986
-
-
Mukrasch, M.D.1
Biernat, J.2
Von Bergen, M.3
Griesinger, C.4
Mandelkow, E.5
Zweckstetter, M.6
-
107
-
-
33947383699
-
NMR investigation of the interaction between the neuronal protein Tau and the microtubules
-
DOI 10.1021/bi061920i
-
A. Sillen, P. Barbier, I. Landrieu, S. Lefebvre, J.M. Wieruszeski, and A. Leroy NMR investigation of the interaction between the neuronal protein tau and the microtubules Biochemistry 46 2007 3055 3064 (Pubitemid 46449129)
-
(2007)
Biochemistry
, vol.46
, Issue.11
, pp. 3055-3064
-
-
Sillen, A.1
Barbier, P.2
Landrieu, I.3
Lefebvre, S.4
Wieruszeski, J.-M.5
Leroy, A.6
Peyrot, V.7
Lippens, G.8
-
108
-
-
33144463940
-
Global hairpin folding of tau in solution
-
DOI 10.1021/bi0521543
-
S. Jeganathan, M. von Bergen, H. Brutlach, H.J. Steinhoff, and E. Mandelkow Global hairpin folding of tau in solution Biochemistry 45 2006 2283 2293 (Pubitemid 43271328)
-
(2006)
Biochemistry
, vol.45
, Issue.7
, pp. 2283-2293
-
-
Jeganathan, S.1
Von Bergen, M.2
Brutlach, H.3
Steinhoff, H.-J.4
Mandelkow, E.5
-
109
-
-
0042924434
-
Differential regulation of microtubule dynamics by three- and four-repeat tau: Implications for the onset of neurodegenerative disease
-
DOI 10.1073/pnas.1633508100
-
D. Panda, J.C. Samuel, M. Massie, S.C. Feinstein, and L. Wilson Differential regulation of microtubule dynamics by three- and four-repeat tau: implications for the onset of neurodegenerative disease Proc Natl Acad Sci USA 100 2003 9548 9553 (Pubitemid 37033965)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.16
, pp. 9548-9553
-
-
Panda, D.1
Samuel, J.C.2
Massie, M.3
Feinstein, S.C.4
Wilson, L.5
-
110
-
-
17144409371
-
Three- and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners: Implications for neurodegeneration
-
DOI 10.1074/jbc.M413490200
-
S.F. Levy, A.C. Leboeuf, M.R. Massie, M.A. Jordan, L. Wilson, and S.C. Feinstein Three- and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners. Implications for neurodegeneration J Biol Chem 280 2005 13520 13528 (Pubitemid 40517243)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.14
, pp. 13520-13528
-
-
Levy, S.F.1
LeBoeuf, A.C.2
Massie, M.R.3
Jordan, M.A.4
Wilson, L.5
Feinstein, S.C.6
-
111
-
-
0037166943
-
MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments
-
DOI 10.1083/jcb.200201048
-
J. Al-Bassam, R.S. Ozer, D. Safer, S. Halpain, and R.A. Milligan MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments J Cell Biol 157 2002 1187 1196 (Pubitemid 34847789)
-
(2002)
Journal of Cell Biology
, vol.157
, Issue.7
, pp. 1187-1196
-
-
Al-Bassam, J.1
Ozer, R.S.2
Safer, D.3
Halpain, S.4
Milligan, R.A.5
-
112
-
-
68949101914
-
Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: A synchrotron x-ray scattering study
-
M.C. Choi, U. Raviv, H.P. Miller, M.R. Gaylord, E. Kiris, and D. Ventimiglia Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: a synchrotron x-ray scattering study Biophys J 97 2009 519 527
-
(2009)
Biophys J
, vol.97
, pp. 519-527
-
-
Choi, M.C.1
Raviv, U.2
Miller, H.P.3
Gaylord, M.R.4
Kiris, E.5
Ventimiglia, D.6
-
113
-
-
0033042978
-
Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation
-
DOI 10.1016/S0014-5793(99)00222-7, PII S0014579399002227
-
R. Dayanandan, M. Van Slegtenhorst, T.G. Mack, L. Ko, S.H. Yen, and K. Leroy Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation FEBS Lett 446 1999 228 232 (Pubitemid 29132731)
-
(1999)
FEBS Letters
, vol.446
, Issue.2-3
, pp. 228-232
-
-
Dayanandan, R.1
Van Slegtenhorst, M.2
Mack, T.G.A.3
Ko, L.4
Yen, S.-H.5
Leroy, K.6
Brion, J.-P.7
Anderton, B.H.8
Hutton, M.9
Lovestone, S.10
-
114
-
-
0032561415
-
Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly
-
DOI 10.1016/S0014-5793(98)01217-4, PII S0014579398012174
-
M. Hasegawa, M.J. Smith, and M. Goedert Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly FEBS Lett 437 1998 207 210 (Pubitemid 28511158)
-
(1998)
FEBS Letters
, vol.437
, Issue.3
, pp. 207-210
-
-
Hasegawa, M.1
Smith, M.J.2
Goedert, M.3
-
115
-
-
0034718571
-
Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias
-
S. Barghorn, Q. Zheng-Fischhofer, M. Ackmann, J. Biernat, M. von Bergen, and E.M. Mandelkow Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias Biochemistry 39 2000 11714 11721
-
(2000)
Biochemistry
, vol.39
, pp. 11714-11721
-
-
Barghorn, S.1
Zheng-Fischhofer, Q.2
Ackmann, M.3
Biernat, J.4
Von Bergen, M.5
Mandelkow, E.M.6
-
116
-
-
33947261950
-
Structural and microtubule binding properties of tau mutants of frontotemporal dementias
-
DOI 10.1021/bi061318s
-
D. Fischer, M.D. Mukrasch, M. von Bergen, A. Klos-Witkowska, J. Biernat, and C. Griesinger Structural and microtubule binding properties of tau mutants of frontotemporal dementias Biochemistry 46 2007 2574 2582 (Pubitemid 46417901)
-
(2007)
Biochemistry
, vol.46
, Issue.10
, pp. 2574-2582
-
-
Fischer, D.1
Mukrasch, M.D.2
Von Bergen, M.3
Klos-Witkowska, A.4
Biemat, J.5
Griesinger, C.6
Mandelkow, E.7
Zweckstetter, M.8
-
117
-
-
33744952341
-
FTDP-17 mutations compromise the ability of Tau to regulate microtubule dynamics in cells
-
DOI 10.1074/jbc.M509420200
-
J.M. Bunker, K. Kamath, L. Wilson, M.A. Jordan, and S.C. Feinstein FTDP-17 mutations compromise the ability of tau to regulate microtubule dynamics in cells J Biol Chem 281 2006 11856 11863 (Pubitemid 43855446)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.17
, pp. 11856-11863
-
-
Bunker, J.M.1
Kamath, K.2
Wilson, L.3
Jordan, M.A.4
Feinstein, S.C.5
-
118
-
-
0037088687
-
Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation
-
DOI 10.1074/jbc.M107716200
-
P. Delobel, S. Flament, M. Hamdane, R. Jakes, A. Rousseau, and A. Delacourte Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation J Biol Chem 277 2002 9199 9205 (Pubitemid 34952999)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.11
, pp. 9199-9205
-
-
Delobel, P.1
Flament, S.2
Hamdane, M.3
Jakes, R.4
Rousseau, A.5
Delacourte, A.6
Vilain, J.-P.7
Goedert, M.8
Buee, L.9
-
119
-
-
0027338266
-
262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
-
DOI 10.1016/0896-6273(93)90279-Z
-
J. Biernat, N. Gustke, G. Drewes, E.M. Mandelkow, and E. Mandelkow Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding Neuron 11 1993 153 163 (Pubitemid 23222542)
-
(1993)
Neuron
, vol.11
, Issue.1
, pp. 153-163
-
-
Biernat, J.1
Gustke, N.2
Drewes, G.3
Mandelkow, E.-M.4
Mandelkow, E.5
-
120
-
-
0038982381
-
Conversion of serine to aspartate imitates phosphorylation-induced changes in the structure and function of microtubule-associated protein tau
-
DOI 10.1074/jbc.272.13.8441
-
J. Leger, M. Kempf, G. Lee, and R. Brandt Conversion of serine to aspartate imitates phosphorylation-induced changes in the structure and function of microtubule-associated protein tau J Biol Chem 272 1997 8441 8446 (Pubitemid 27147805)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.13
, pp. 8441-8446
-
-
Leger, J.1
Kempf, M.2
Lee, G.3
Brandt, R.4
-
121
-
-
1642280378
-
Pseudophosphorylation of tau protein alters its ability for self-aggregation
-
C. Haase, J.T. Stieler, T. Arendt, and M. Holzer Pseudophosphorylation of tau protein alters its ability for self-aggregation J Neurochem 88 2004 1509 1520 (Pubitemid 38366927)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.6
, pp. 1509-1520
-
-
Haase, C.1
Stieler, J.T.2
Arendt, T.3
Holzer, M.4
-
122
-
-
0346457015
-
Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3β (GSK3β) plays a critical role in regulating tau's ability to bind and stabilize microtubules
-
J.H. Cho, and G.V. Johnson Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3beta (GSK3beta) plays a critical role in regulating tau's ability to bind and stabilize microtubules J Neurochem 88 2004 349 358 (Pubitemid 38084551)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.2
, pp. 349-358
-
-
Cho, J.-H.1
Johnson, G.V.W.2
-
123
-
-
10944256690
-
Inability of tau to properly regulate neuronal microtubule dynamics: A loss-of-function mechanism by which tau might mediate neuronal cell death
-
DOI 10.1016/j.bbadis.2004.07.002, PII S0925443904001334
-
S.C. Feinstein, and L. Wilson Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death Biochim Biophys Acta 1739 2005 268 279 (Pubitemid 40018544)
-
(2005)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1739
, Issue.2
, pp. 268-279
-
-
Feinstein, S.C.1
Wilson, L.2
-
124
-
-
77958065504
-
Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy
-
K.R. Brunden, B. Zhang, J. Carroll, Y. Yao, J.S. Potuzak, and A.M. Hogan Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy J Neurosci 30 2010 13861 13866
-
(2010)
J Neurosci
, vol.30
, pp. 13861-13866
-
-
Brunden, K.R.1
Zhang, B.2
Carroll, J.3
Yao, Y.4
Potuzak, J.S.5
Hogan, A.M.6
-
125
-
-
70350455072
-
Axonal transport defects in neurodegenerative diseases
-
G.A. Morfini, M. Burns, L.I. Binder, N.M. Kanaan, N. LaPointe, and D.A. Bosco Axonal transport defects in neurodegenerative diseases J Neurosci 29 2009 12776 12786
-
(2009)
J Neurosci
, vol.29
, pp. 12776-12786
-
-
Morfini, G.A.1
Burns, M.2
Binder, L.I.3
Kanaan, N.M.4
Lapointe, N.5
Bosco, D.A.6
-
126
-
-
0032476645
-
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease
-
DOI 10.1083/jcb.143.3.777
-
A. Ebneth, R. Godemann, K. Stamer, S. Illenberger, B. Trinczek, and E. Mandelkow Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease J Cell Biol 143 1998 777 794 (Pubitemid 28512571)
-
(1998)
Journal of Cell Biology
, vol.143
, Issue.3
, pp. 777-794
-
-
Ebneth, A.1
Godemann, R.2
Stamer, K.3
Illenberger, S.4
Trinczek, B.5
Mandelkow, E.-M.6
Mandelkow, E.7
-
127
-
-
0032799381
-
Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles
-
B. Trinczek, A. Ebneth, E.M. Mandelkow, and E. Mandelkow Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles J Cell Sci 112 Pt 14 1999 2355 2367 (Pubitemid 29381026)
-
(1999)
Journal of Cell Science
, vol.112
, Issue.14
, pp. 2355-2367
-
-
Trinczek, B.1
Ebneth, A.2
Mandelkow, E.-M.3
Mandelkow, E.4
-
128
-
-
0035139540
-
Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy
-
G.F. Hall, V.M. Lee, G. Lee, and J. Yao Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy Am J Pathol 158 2001 235 246 (Pubitemid 32096489)
-
(2001)
American Journal of Pathology
, vol.158
, Issue.1
, pp. 235-246
-
-
Hall, G.F.1
Lee, V.M.-Y.2
Lee, G.3
Yao, J.4
-
129
-
-
0037128935
-
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
-
DOI 10.1083/jcb.200108057
-
K. Stamer, R. Vogel, E. Thies, E. Mandelkow, and E.M. Mandelkow Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress J Cell Biol 156 2002 1051 1063 (Pubitemid 34839854)
-
(2002)
Journal of Cell Biology
, vol.156
, Issue.6
, pp. 1051-1063
-
-
Stamer, K.1
Vogel, R.2
Thies, E.3
Mandelkow, E.4
Mandelkow, E.-M.5
-
130
-
-
0345276565
-
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
-
DOI 10.1016/j.neurobiolaging.2003.04.007
-
E.M. Mandelkow, K. Stamer, R. Vogel, E. Thies, and E. Mandelkow Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses Neurobiol Aging 24 2003 1079 1085 (Pubitemid 37487885)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.8
, pp. 1079-1085
-
-
Mandelkow, E.-M.1
Stamer, K.2
Vogel, R.3
Thies, E.4
Mandelkow, E.5
-
131
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
T. Ishihara, M. Hong, B. Zhang, Y. Nakagawa, M.K. Lee, and J.Q. Trojanowski Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform Neuron 24 1999 751 762
-
(1999)
Neuron
, vol.24
, pp. 751-762
-
-
Ishihara, T.1
Hong, M.2
Zhang, B.3
Nakagawa, Y.4
Lee, M.K.5
Trojanowski, J.Q.6
-
132
-
-
57349172663
-
Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia
-
L.M. Ittner, T. Fath, Y.D. Ke, M. Bi, J. van Eersel, and K.M. Li Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia Proc Natl Acad Sci USA 105 2008 15997 16002
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15997-16002
-
-
Ittner, L.M.1
Fath, T.2
Ke, Y.D.3
Bi, M.4
Van Eersel, J.5
Li, K.M.6
-
133
-
-
27844470590
-
Molecular motors implicated in the axonal transport of tau and α-synuclein
-
DOI 10.1242/jcs.02558
-
M.A. Utton, W.J. Noble, J.E. Hill, B.H. Anderton, and D.P. Hanger Molecular motors implicated in the axonal transport of tau and alpha-synuclein J Cell Sci 118 2005 4645 4654 (Pubitemid 41646375)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.20
, pp. 4645-4654
-
-
Utton, M.A.1
Noble, W.J.2
Hill, J.E.3
Anderton, B.H.4
-
134
-
-
39449138356
-
Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: Neurofilaments attenuate tau-mediated neurite instability
-
DOI 10.1002/cm.20243
-
M. Dubey, P. Chaudhury, H. Kabiru, and T.B. Shea Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: neurofilaments attenuate tau-mediated neurite instability Cell Motil Cytoskeleton 65 2008 89 99 (Pubitemid 351272971)
-
(2008)
Cell Motility and the Cytoskeleton
, vol.65
, Issue.2
, pp. 89-99
-
-
Dubey, M.1
Chaudhury, P.2
Kabiru, H.3
Shea, T.B.4
-
135
-
-
0030561943
-
Tau proteins bind to kinesin and modulate its activation by microtubules
-
V. Jancsik, D. Filliol, and A. Rendon Tau proteins bind to kinesin and modulate its activation by microtubules Neurobiology (Bp) 4 1996 417 429 (Pubitemid 29113088)
-
(1996)
Neurobiology
, vol.4
, Issue.4
, pp. 417-429
-
-
Jancsik, V.1
Filliol, D.2
Rendon, A.3
-
136
-
-
51349143580
-
Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin
-
I. Cuchillo-Ibanez, A. Seereeram, H.L. Byers, K.Y. Leung, M.A. Ward, and B.H. Anderton Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin FASEB J 22 2008 3186 3195
-
(2008)
FASEB J
, vol.22
, pp. 3186-3195
-
-
Cuchillo-Ibanez, I.1
Seereeram, A.2
Byers, H.L.3
Leung, K.Y.4
Ward, M.A.5
Anderton, B.H.6
-
137
-
-
35649028013
-
Interaction of tau protein with the dynactin complex
-
DOI 10.1038/sj.emboj.7601878, PII 7601878
-
E. Magnani, J. Fan, L. Gasparini, M. Golding, M. Williams, and G. Schiavo Interaction of tau protein with the dynactin complex EMBO J 26 2007 4546 4554 (Pubitemid 350036634)
-
(2007)
EMBO Journal
, vol.26
, Issue.21
, pp. 4546-4554
-
-
Magnani, E.1
Fan, J.2
Gasparini, L.3
Golding, M.4
Williams, M.5
Schiavo, G.6
Goedert, M.7
Amos, L.A.8
Spillantini, M.G.9
-
138
-
-
0037119947
-
Single-molecule investigation of the interference between kinesin, tau and MAP2c
-
A. Seitz, H. Kojima, K. Oiwa, E.M. Mandelkow, Y.H. Song, and E. Mandelkow Single-molecule investigation of the interference between kinesin, tau and MAP2c EMBO J 21 2002 4896 4905
-
(2002)
EMBO J
, vol.21
, pp. 4896-4905
-
-
Seitz, A.1
Kojima, H.2
Oiwa, K.3
Mandelkow, E.M.4
Song, Y.H.5
Mandelkow, E.6
-
139
-
-
39749165656
-
Differential regulation of dynein and kinesin motor proteins by tau
-
DOI 10.1126/science.1152993
-
R. Dixit, J.L. Ross, Y.E. Goldman, and E.L. Holzbaur Differential regulation of dynein and kinesin motor proteins by tau Science 319 2008 1086 1089 (Pubitemid 351300789)
-
(2008)
Science
, vol.319
, Issue.5866
, pp. 1086-1089
-
-
Dixit, R.1
Ross, J.L.2
Goldman, Y.E.3
Holzbaur, E.L.F.4
-
140
-
-
33846118789
-
Multiple-motor based transport and its regulation by Tau
-
DOI 10.1073/pnas.0607919104
-
M. Vershinin, B.C. Carter, D.S. Razafsky, S.J. King, and S.P. Gross Multiple-motor based transport and its regulation by Tau Proc Natl Acad Sci USA 104 2007 87 92 (Pubitemid 46067989)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.1
, pp. 87-92
-
-
Vershinin, M.1
Carter, B.C.2
Razafsky, D.S.3
King, S.J.4
Gross, S.P.5
-
141
-
-
68949105821
-
Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease
-
L.M. Ittner, Y.D. Ke, and J. Gotz Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease J Biol Chem 284 2009 20909 20916
-
(2009)
J Biol Chem
, vol.284
, pp. 20909-20916
-
-
Ittner, L.M.1
Ke, Y.D.2
Gotz, J.3
-
142
-
-
40449093880
-
Tau-induced traffic jams reflect organelles accumulation at points of microtubule polar mismatching
-
DOI 10.1111/j.1600-0854.2007.00695.x
-
O.A. Shemesh, H. Erez, I. Ginzburg, and M.E. Spira Tau-induced traffic jams reflect organelles accumulation at points of microtubule polar mismatching Traffic 9 2008 458 471 (Pubitemid 351351608)
-
(2008)
Traffic
, vol.9
, Issue.4
, pp. 458-471
-
-
Shemesh, O.A.1
Erez, H.2
Ginzburg, I.3
Spira, M.E.4
-
143
-
-
34250317264
-
Tau binding to microtubules does not directly affect microtubule-based vesicle motility
-
DOI 10.1002/jnr.21154
-
G. Morfini, G. Pigino, N. Mizuno, M. Kikkawa, and S.T. Brady Tau binding to microtubules does not directly affect microtubule-based vesicle motility J Neurosci Res 85 2007 2620 2630 (Pubitemid 47344564)
-
(2007)
Journal of Neuroscience Research
, vol.85
, Issue.12
, pp. 2620-2630
-
-
Morfini, G.1
Pigino, G.2
Mizuno, N.3
Kikkawa, M.4
Brady, S.T.5
-
144
-
-
62849088641
-
The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity
-
N.E. LaPointe, G. Morfini, G. Pigino, I.N. Gaisina, A.P. Kozikowski, and L.I. Binder The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity J Neurosci Res 87 2009 440 451
-
(2009)
J Neurosci Res
, vol.87
, pp. 440-451
-
-
Lapointe, N.E.1
Morfini, G.2
Pigino, G.3
Gaisina, I.N.4
Kozikowski, A.P.5
Binder, L.I.6
-
145
-
-
39549117998
-
Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
-
DOI 10.1523/JNEUROSCI.5242-07.2008
-
A. Yuan, A. Kumar, C. Peterhoff, K. Duff, and R.A. Nixon Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice J Neurosci 28 2008 1682 1687 (Pubitemid 351287026)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.7
, pp. 1682-1687
-
-
Yuan, A.1
Kumar, A.2
Peterhoff, C.3
Duff, K.4
Nixon, R.A.5
-
146
-
-
0018129689
-
Evidence for actin filament-microtubule interaction mediated by microtubule-associated proteins
-
DOI 10.1083/jcb.78.3.958
-
L.M. Griffith, and T.D. Pollard Evidence for actin filament-microtubule interaction mediated by microtubule-associated proteins J Cell Biol 78 1978 958 965 (Pubitemid 9007434)
-
(1978)
Journal of Cell Biology
, vol.78
, Issue.3
, pp. 958-965
-
-
Griffith, L.M.1
Pollard, T.D.2
-
147
-
-
0020287381
-
The interaction of actin filaments with microtubules and microtubule-associated proteins
-
L.M. Griffith, and T.D. Pollard The interaction of actin filaments with microtubules and microtubule-associated proteins J Biol Chem 257 1982 9143 9151 (Pubitemid 12001882)
-
(1982)
Journal of Biological Chemistry
, vol.257
, Issue.15
, pp. 9143-9151
-
-
Griffith, L.M.1
Pollard, T.D.2
-
148
-
-
0025335664
-
The tubulin-binding sequence of brain microtubule-associated proteins, tau and MAP-2, is also involved in actin binding
-
I. Correas, R. Padilla, and J. Avila The tubulin-binding sequence of brain microtubule-associated proteins, tau and MAP-2, is also involved in actin binding Biochem J 269 1990 61 64 (Pubitemid 20210840)
-
(1990)
Biochemical Journal
, vol.269
, Issue.1
, pp. 61-64
-
-
Correas, I.1
Padilla, R.2
Avila, J.3
-
149
-
-
0027261518
-
A τ fragment containing a repetitive sequence induces bundling of actin filaments
-
D.M. Moraga, P. Nunez, J. Garrido, and R.B. Maccioni A tau fragment containing a repetitive sequence induces bundling of actin filaments J Neurochem 61 1993 979 986 (Pubitemid 23241236)
-
(1993)
Journal of Neurochemistry
, vol.61
, Issue.3
, pp. 979-986
-
-
Moraga, D.M.1
Nunez, P.2
Garrido, J.3
Maccioni, R.B.4
-
150
-
-
0027978832
-
Microfilament-associated growth cone component depends upon Tau for its intracellular localization
-
DOI 10.1002/cm.970290204
-
M. DiTella, F. Feiguin, G. Morfini, and A. Caceres Microfilament- associated growth cone component depends upon Tau for its intracellular localization Cell Motil Cytoskeleton 29 1994 117 130 (Pubitemid 24303011)
-
(1994)
Cell Motility and the Cytoskeleton
, vol.29
, Issue.2
, pp. 117-130
-
-
DiTella, M.1
Feiguin, F.2
Morfini, G.3
Caceres, A.4
-
151
-
-
0032976176
-
Tau is required for neurite outgrowth and growth cone motility of chick sensory neurons
-
DOI 10.1002/(SICI)1097-0169(1999)43:3<232::AID-CM6>3.0.CO;2-7
-
C.W. Liu, G. Lee, and D.G. Jay Tau is required for neurite outgrowth and growth cone motility of chick sensory neurons Cell Motil Cytoskeleton 43 1999 232 242 (Pubitemid 29305099)
-
(1999)
Cell Motility and the Cytoskeleton
, vol.43
, Issue.3
, pp. 232-242
-
-
Liu, C.-W.A.1
Lee, G.2
Jay, D.G.3
-
152
-
-
33746565567
-
Tau associates with actin in differentiating PC12 cells
-
DOI 10.1096/fj.05-5206com
-
J.Z. Yu, and M.M. Rasenick Tau associates with actin in differentiating PC12 cells FASEB J 20 2006 1452 1461 (Pubitemid 44943853)
-
(2006)
FASEB Journal
, vol.20
, Issue.9
, pp. 1452-1461
-
-
Yu, J.-Z.1
Rasenick, M.M.2
-
153
-
-
1842432582
-
MAP2c, but not tau, binds and bundles F-actin via its microtubule binding domain
-
DOI 10.1016/j.cub.2004.01.058, PII S0960982204000491
-
B. Roger, J. Al-Bassam, L. Dehmelt, R.A. Milligan, and S. Halpain MAP2c,
-
(2004)
Current Biology
, vol.14
, Issue.5
, pp. 363-371
-
-
Roger, B.1
Al-Bassam, J.2
Dehmelt, L.3
Milligan, R.A.4
Halpain, S.5
-
154
-
-
0036854327
-
Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity
-
DOI 10.1091/mbc.02-03-0046
-
J. Biernat, Y.Z. Wu, T. Timm, Q. Zheng-Fischhofer, E. Mandelkow, and L. Meijer Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity Mol Biol Cell 13 2002 4013 4028 (Pubitemid 35398567)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.11
, pp. 4013-4028
-
-
Biernat, J.1
Wu, Y.-Z.2
Timm, T.3
Zheng-Fischhofer, Q.4
Mandelkow, E.5
Meijer, L.6
Mandelkow, E.-M.7
-
155
-
-
34047166439
-
Tau impacts on growth-factor-stimulated actin remodeling
-
DOI 10.1242/jcs.03378
-
V.M. Sharma, J.M. Litersky, K. Bhaskar, and G. Lee Tau impacts on growth-factor-stimulated actin remodeling J Cell Sci 120 2007 748 757 (Pubitemid 46523477)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.5
, pp. 748-757
-
-
Sharma, V.M.1
Litersky, J.M.2
Bhaskar, K.3
Lee, G.4
-
156
-
-
0028785525
-
Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain
-
R. Brandt, J. Leger, and G. Lee Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain J Cell Biol 131 1995 1327 1340
-
(1995)
J Cell Biol
, vol.131
, pp. 1327-1340
-
-
Brandt, R.1
Leger, J.2
Lee, G.3
-
157
-
-
0029922250
-
Tau is enriched on dynamic microtubules in the distal region of growing axons
-
M.M. Black, T. Slaughter, S. Moshiach, M. Obrocka, and I. Fischer Tau is enriched on dynamic microtubules in the distal region of growing axons J Neurosci 16 1996 3601 3619 (Pubitemid 26149498)
-
(1996)
Journal of Neuroscience
, vol.16
, Issue.11
, pp. 3601-3619
-
-
Black, M.M.1
Slaughter, T.2
Moshiach, S.3
Obrocka, M.4
Fischer, I.5
-
158
-
-
33947286683
-
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
-
DOI 10.1038/ncb1528, PII NCB1528
-
T.A. Fulga, I. Elson-Schwab, V. Khurana, M.L. Steinhilb, T.L. Spires, and B.T. Hyman Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo Nat Cell Biol 9 2007 139 148 (Pubitemid 46420856)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.2
, pp. 139-148
-
-
Fulga, T.A.1
Elson-Schwab, I.2
Khurana, V.3
Steinhilb, M.L.4
Spires, T.L.5
Hyman, B.T.6
Feany, M.B.7
-
159
-
-
0034282106
-
Neurodegenerative stimuli induce persistent ADF/cofilin-actin rods that disrupt distal neurite function
-
L.S. Minamide, A.M. Striegl, J.A. Boyle, P.J. Meberg, and J.R. Bamburg Neurodegenerative stimuli induce persistent ADF/cofilin-actin rods that disrupt distal neurite function Nat Cell Biol 2 2000 628 636
-
(2000)
Nat Cell Biol
, vol.2
, pp. 628-636
-
-
Minamide, L.S.1
Striegl, A.M.2
Boyle, J.A.3
Meberg, P.J.4
Bamburg, J.R.5
-
160
-
-
61349097283
-
Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases
-
Y. Yu, X. Run, Z. Liang, Y. Li, F. Liu, and Y. Liu Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases J Neurochem 108 2009 1480 1494
-
(2009)
J Neurochem
, vol.108
, pp. 1480-1494
-
-
Yu, Y.1
Run, X.2
Liang, Z.3
Li, Y.4
Liu, F.5
Liu, Y.6
-
161
-
-
0028978701
-
Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau
-
P. Seubert, M. Mawal-Dewan, R. Barbour, R. Jakes, M. Goedert, and G.V. Johnson Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau J Biol Chem 270 1995 18917 18922
-
(1995)
J Biol Chem
, vol.270
, pp. 18917-18922
-
-
Seubert, P.1
Mawal-Dewan, M.2
Barbour, R.3
Jakes, R.4
Goedert, M.5
Johnson, G.V.6
-
162
-
-
33746879943
-
Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation
-
DOI 10.1111/j.1471-4159.2006.04059.x
-
S. Sato, R.L. Cerny, J.L. Buescher, and T. Ikezu Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation J Neurochem 98 2006 1573 1584 (Pubitemid 44200447)
-
(2006)
Journal of Neurochemistry
, vol.98
, Issue.5
, pp. 1573-1584
-
-
Sato, S.1
Cerny, R.L.2
Buescher, J.L.3
Ikezu, T.4
-
163
-
-
0030963035
-
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases
-
DOI 10.1016/S0014-5793(97)00483-3, PII S0014579397004833
-
M. Goedert, M. Hasegawa, R. Jakes, S. Lawler, A. Cuenda, and P. Cohen Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases FEBS Lett 409 1997 57 62 (Pubitemid 27248567)
-
(1997)
FEBS Letters
, vol.409
, Issue.1
, pp. 57-62
-
-
Goedert, M.1
Hasegawa, M.2
Jakes, R.3
Lawler, S.4
Cuenda, A.5
Cohen, P.6
-
164
-
-
51349109221
-
Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome
-
F. Liu, Z. Liang, J. Wegiel, Y.W. Hwang, K. Iqbal, and I. Grundke-Iqbal Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome FASEB J 22 2008 3224 3233
-
(2008)
FASEB J
, vol.22
, pp. 3224-3233
-
-
Liu, F.1
Liang, Z.2
Wegiel, J.3
Hwang, Y.W.4
Iqbal, K.5
Grundke-Iqbal, I.6
-
165
-
-
0034067992
-
Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: Differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase- 3β
-
DOI 10.1046/j.1471-4159.2000.0741587.x
-
C.H. Reynolds, J.C. Betts, W.P. Blackstock, A.R. Nebreda, and B.H. Anderton Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta J Neurochem 74 2000 1587 1595 (Pubitemid 30163980)
-
(2000)
Journal of Neurochemistry
, vol.74
, Issue.4
, pp. 1587-1595
-
-
Reynolds, C.H.1
Betts, J.C.2
Blackstock, W.P.3
Nebreda, A.R.4
Anderton, B.H.5
-
166
-
-
36849075621
-
DYRK1A-mediated hyperphosphorylation of Tau: A functional link between down syndrome and Alzheimer disease
-
DOI 10.1074/jbc.M707358200
-
S.R. Ryoo, H.K. Jeong, C. Radnaabazar, J.J. Yoo, H.J. Cho, and H.W. Lee DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease J Biol Chem 282 2007 34850 34857 (Pubitemid 350232475)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.48
, pp. 34850-34857
-
-
Ryoo, S.-R.1
Hey, K.J.2
Radnaabazar, C.3
Yoo, J.-J.4
Cho, H.-J.5
Lee, H.-W.6
Kim, I.-S.7
Cheon, Y.-H.8
Young, S.A.9
Chung, S.-H.10
Song, W.-J.11
-
168
-
-
0028899714
-
Proline-directed and non-proline-directed phosphorylation of PHF-tau
-
M. Morishima-Kawashima, M. Hasegawa, K. Takio, M. Suzuki, H. Yoshida, and K. Titani Proline-directed and non-proline-directed phosphorylation of PHF-tau J Biol Chem 270 1995 823 829
-
(1995)
J Biol Chem
, vol.270
, pp. 823-829
-
-
Morishima-Kawashima, M.1
Hasegawa, M.2
Takio, K.3
Suzuki, M.4
Yoshida, H.5
Titani, K.6
-
169
-
-
12644260802
-
The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology
-
DOI 10.1074/jbc.271.51.32789
-
G. Carmel, E.M. Mager, L.I. Binder, and J. Kuret The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology J Biol Chem 271 1996 32789 32795 (Pubitemid 27008707)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.51
, pp. 32789-32795
-
-
Carmel, G.1
Mager, E.M.2
Binder, L.I.3
Kuret, J.4
-
170
-
-
4544248870
-
Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease
-
DOI 10.1523/JNEUROSCI.1988-04.2004
-
P.M. Horowitz, K.R. Patterson, A.L. Guillozet-Bongaarts, M.R. Reynolds, C.A. Carroll, and S.T. Weintraub Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease J Neurosci 24 2004 7895 7902 (Pubitemid 39215694)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.36
, pp. 7895-7902
-
-
Horowitz, P.M.1
Patterson, K.R.2
Guillozet-Bongaarts, A.L.3
Reynolds, M.R.4
Carroll, C.A.5
Weintraub, S.T.6
Bennett, D.A.7
Cryns, V.L.8
Berry, R.W.9
Binder, L.I.10
-
171
-
-
0024109687
-
Epitopes that span the tau molecule are shared with paired helical filaments
-
K.S. Kosik, L.D. Orecchio, L. Binder, J.Q. Trojanowski, V.M. Lee, and G. Lee Epitopes that span the tau molecule are shared with paired helical filaments Neuron 1 1988 817 825
-
(1988)
Neuron
, vol.1
, pp. 817-825
-
-
Kosik, K.S.1
Orecchio, L.D.2
Binder, L.3
Trojanowski, J.Q.4
Lee, V.M.5
Lee, G.6
-
172
-
-
0026758096
-
Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes
-
M. Mercken, M. Vandermeeren, U. Lubke, J. Six, J. Boons, and A. Van de Voorde Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes Acta Neuropathol 84 1992 265 272
-
(1992)
Acta Neuropathol
, vol.84
, pp. 265-272
-
-
Mercken, M.1
Vandermeeren, M.2
Lubke, U.3
Six, J.4
Boons, J.5
Van De Voorde, A.6
-
173
-
-
0033198043
-
CAMP-dependent protein kinase phosphorylations on Tau in Alzheimer's disease
-
G.A. Jicha, C. Weaver, E. Lane, C. Vianna, Y. Kress, and J. Rockwood cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease J Neurosci 19 1999 7486 7494 (Pubitemid 29404605)
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.17
, pp. 7486-7494
-
-
Jicha, G.A.1
Weaver, C.2
Lane, E.3
Vianna, C.4
Kress, Y.5
Rockwood, J.6
Davies, P.7
-
174
-
-
0027984739
-
Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: Identification of phosphorylation sites in tau protein
-
M. Goedert, R. Jakes, R.A. Crowther, P. Cohen, E. Vanmechelen, and M. Vandermeeren Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein Biochem J 301 Pt 3 1994 871 877 (Pubitemid 24239324)
-
(1994)
Biochemical Journal
, vol.301
, Issue.3
, pp. 871-877
-
-
Goedert, M.1
Jakes, R.2
Crowther, R.A.3
Cohen, P.4
Vanmechelen, E.5
Vandermeeren, M.6
Cras, P.7
-
175
-
-
0034282067
-
Conformational change as one of the earliest alterations of tau in Alzheimer's disease
-
C.L. Weaver, M. Espinoza, Y. Kress, and P. Davies Conformational change as one of the earliest alterations of tau in Alzheimer's disease Neurobiol Aging 21 2000 719 727
-
(2000)
Neurobiol Aging
, vol.21
, pp. 719-727
-
-
Weaver, C.L.1
Espinoza, M.2
Kress, Y.3
Davies, P.4
-
176
-
-
0030783142
-
A conformation- and phosphorylation-dependent antibody recognizing the paired helical filaments of Alzheimer's disease
-
G.A. Jicha, E. Lane, I. Vincent, L. Otvos Jr., R. Hoffmann, and P. Davies A conformation- and phosphorylation-dependent antibody recognizing the paired helical filaments of Alzheimer's disease J Neurochem 69 1997 2087 2095 (Pubitemid 27452756)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.5
, pp. 2087-2095
-
-
Jicha, G.A.1
Lane, E.2
Vincent, I.3
Otvos Jr., L.4
Hoffmann, R.5
Davies, P.6
-
177
-
-
0028593606
-
Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404
-
L. Otvos Jr., L. Feiner, E. Lang, G.I. Szendrei, M. Goedert, and V.M. Lee Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404 J Neurosci Res 39 1994 669 673
-
(1994)
J Neurosci Res
, vol.39
, pp. 669-673
-
-
Otvos Jr., L.1
Feiner, L.2
Lang, E.3
Szendrei, G.I.4
Goedert, M.5
Lee, V.M.6
-
178
-
-
12144288564
-
Phosphorylation of Tau by Fyn: Implications for Alzheimer's Disease
-
DOI 10.1523/JNEUROSCI.4162-03.2004
-
G. Lee, R. Thangavel, V.M. Sharma, J.M. Litersky, K. Bhaskar, and S.M. Fang Phosphorylation of tau by fyn: implications for Alzheimer's disease J Neurosci 24 2004 2304 2312 (Pubitemid 38314562)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.9
, pp. 2304-2312
-
-
Lee, G.1
Thangavel, R.2
Sharma, V.M.3
Litersky, J.M.4
Bhaskar, K.5
Fang, S.M.6
Do, L.H.7
Andreadis, A.8
Van Hoesen, G.9
Ksiezak-Reding, H.10
-
179
-
-
0024461007
-
Tau protein becomes long and stiff upon phosphorylation: Correlation between paracrystalline structure and degree of dephosphorylation
-
T. Hagestedt, B. Lichtenberg, H. Wille, E.M. Mandelkow, and E. Mandelkow Tau protein becomes long and stiff upon phosphorylation: correlation between paracrystalline structure and degree of phosphorylation J Cell Biol 109 1989 1643 1651 (Pubitemid 19251214)
-
(1989)
Journal of Cell Biology
, vol.109
, Issue.4
, pp. 1643-1651
-
-
Hagestedt, T.1
Lichtenberg, B.2
Wille, H.3
Mandelkow, E.-M.4
Mankelkow, E.5
-
180
-
-
57649129018
-
Proline-directed pseudo-phosphorylation at AT8 and PHF1 epitopes induces a compaction of the paperclip folding of Tau and generates a pathological (MC-1) conformation
-
S. Jeganathan, A. Hascher, S. Chinnathambi, J. Biernat, E.M. Mandelkow, and E. Mandelkow Proline-directed pseudo-phosphorylation at AT8 and PHF1 epitopes induces a compaction of the paperclip folding of Tau and generates a pathological (MC-1) conformation J Biol Chem 283 2008 32066 32076
-
(2008)
J Biol Chem
, vol.283
, pp. 32066-32076
-
-
Jeganathan, S.1
Hascher, A.2
Chinnathambi, S.3
Biernat, J.4
Mandelkow, E.M.5
Mandelkow, E.6
-
181
-
-
33646080573
-
Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: In vitro evidence and implications for tangle formation in vivo
-
A.L. Guillozet-Bongaarts, M.E. Cahill, V.L. Cryns, M.R. Reynolds, R.W. Berry, and L.I. Binder Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo J Neurochem 97 2006 1005 1014
-
(2006)
J Neurochem
, vol.97
, pp. 1005-1014
-
-
Guillozet-Bongaarts, A.L.1
Cahill, M.E.2
Cryns, V.L.3
Reynolds, M.R.4
Berry, R.W.5
Binder, L.I.6
-
182
-
-
0031052339
-
Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5
-
DOI 10.1023/A:1006883924775
-
A. Sengupta, Q. Wu, I. Grundke-Iqbal, K. Iqbal, and T.J. Singh Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5 Mol Cell Biochem 167 1997 99 105 (Pubitemid 27081337)
-
(1997)
Molecular and Cellular Biochemistry
, vol.167
, Issue.1-2
, pp. 99-105
-
-
Sengupta, A.1
Wu, Q.2
Grundke-Iqbal, I.3
Iqbal, K.4
Singh, T.J.5
-
183
-
-
4844219627
-
Promotion of hyperphosphorylation by frontotemporal dementia tau mutations
-
DOI 10.1074/jbc.M405131200
-
C. Alonso Adel, A. Mederlyova, M. Novak, I. Grundke-Iqbal, and K. Iqbal Promotion of hyperphosphorylation by frontotemporal dementia tau mutations J Biol Chem 279 2004 34873 34881 (Pubitemid 39318122)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34873-34881
-
-
Alonso, A.D.C.1
Mederlyova, A.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
184
-
-
0028986916
-
β-amyloid fibrils induce tau phosphorylation and loss of microtubule binding
-
J. Busciglio, A. Lorenzo, J. Yeh, and B.A. Yankner β-amyloid fibrils induce tau phosphorylation and loss of microtubule binding Neuron 14 1995 879 888
-
(1995)
Neuron
, vol.14
, pp. 879-888
-
-
Busciglio, J.1
Lorenzo, A.2
Yeh, J.3
Yankner, B.A.4
-
185
-
-
0030044463
-
Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta
-
A. Takashima, K. Noguchi, G. Michel, M. Mercken, M. Hoshi, and K. Ishiguro Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta Neurosci Lett 203 1996 33 36
-
(1996)
Neurosci Lett
, vol.203
, pp. 33-36
-
-
Takashima, A.1
Noguchi, K.2
Michel, G.3
Mercken, M.4
Hoshi, M.5
Ishiguro, K.6
-
186
-
-
0033957692
-
PD98059 prevents neurite degeneration induced by fibrillar β-amyloid in mature hippocampal neurons
-
DOI 10.1046/j.1471-4159.2000.0740125.x
-
M. Rapoport, and A. Ferreira PD98059 prevents neurite degeneration induced by fibrillar beta-amyloid in mature hippocampal neurons J Neurochem 74 2000 125 133 (Pubitemid 30012762)
-
(2000)
Journal of Neurochemistry
, vol.74
, Issue.1
, pp. 125-133
-
-
Rapoport, M.1
Ferreira, A.2
-
187
-
-
0027945346
-
Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau
-
DOI 10.1016/0896-6273(94)90264-X
-
E.S. Matsuo, R.W. Shin, M.L. Billingsley, A. Van deVoorde, M. O'Connor, and J.Q. Trojanowski Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau Neuron 13 1994 989 1002 (Pubitemid 24347311)
-
(1994)
Neuron
, vol.13
, Issue.4
, pp. 989-1002
-
-
Matsuo, E.S.1
Shin, R.-W.2
Billingsley, M.L.3
Van DeVoorde, A.4
O'Connor, M.5
Trojanowski, J.Q.6
Lee, V.M.-Y.7
-
188
-
-
0030461275
-
Regulation of the phosphorylation state and microtubule-binding activity of tau by protein phosphatase 2A
-
DOI 10.1016/S0896-6273(00)80250-0
-
E. Sontag, V. Nunbhakdi-Craig, G. Lee, G.S. Bloom, and M.C. Mumby Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A Neuron 17 1996 1201 1207 (Pubitemid 27021104)
-
(1996)
Neuron
, vol.17
, Issue.6
, pp. 1201-1207
-
-
Sontag, E.1
Nunbhakdi-Craig, V.2
Lee, G.3
Bloom, G.S.4
Mumby, M.C.5
-
189
-
-
0033520355
-
Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies
-
E. Sontag, V. Nunbhakdi-Craig, G. Lee, R. Brandt, C. Kamibayashi, and J. Kuret Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies J Biol Chem 274 1999 25490 25498
-
(1999)
J Biol Chem
, vol.274
, pp. 25490-25498
-
-
Sontag, E.1
Nunbhakdi-Craig, V.2
Lee, G.3
Brandt, R.4
Kamibayashi, C.5
Kuret, J.6
-
190
-
-
0032555642
-
Protein phosphatase 1 is targeted to microtubules by the microtubule- associated protein tau
-
DOI 10.1074/jbc.273.34.21901
-
H. Liao, Y. Li, D.L. Brautigan, and G.G. Gundersen Protein phosphatase 1 is targeted to microtubules by the microtubule-associated protein Tau J Biol Chem 273 1998 21901 21908 (Pubitemid 28405368)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.34
, pp. 21901-21908
-
-
Liao, H.1
Li, Y.2
Brautigan, D.L.3
Gundersen, G.G.4
-
191
-
-
17644410079
-
Phosphothreonine-212 of alzheimer abnormally hyperphosphorylated tau is a preferred substrate of protein phosphatase-1
-
DOI 10.1007/s11064-005-2483-9
-
A. Rahman, I. Grundke-Iqbal, and K. Iqbal Phosphothreonine-212 of Alzheimer abnormally hyperphosphorylated tau is a preferred substrate of protein phosphatase-1 Neurochem Res 30 2005 277 287 (Pubitemid 40569212)
-
(2005)
Neurochemical Research
, vol.30
, Issue.2
, pp. 277-287
-
-
Rahman, A.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
192
-
-
27644478606
-
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
-
DOI 10.1111/j.1460-9568.2005.04391.x
-
F. Liu, I. Grundke-Iqbal, K. Iqbal, and C.X. Gong Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation Eur J Neurosci 22 2005 1942 1950 (Pubitemid 41579384)
-
(2005)
European Journal of Neuroscience
, vol.22
, Issue.8
, pp. 1942-1950
-
-
Liu, F.1
Grundke-Iqbal, I.2
Iqbal, K.3
Gong, C.-X.4
-
193
-
-
0033788787
-
Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations
-
M. Goedert, S. Satumtira, R. Jakes, M.J. Smith, C. Kamibayashi, and C.L. White 3rd Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations J Neurochem 75 2000 2155 2162
-
(2000)
J Neurochem
, vol.75
, pp. 2155-2162
-
-
Goedert, M.1
Satumtira, S.2
Jakes, R.3
Smith, M.J.4
Kamibayashi, C.5
White III, C.L.6
-
194
-
-
0344505849
-
Tau interacts with src-family non-receptor tyrosine kinases
-
G. Lee, S.T. Newman, D.L. Gard, H. Band, and G. Panchamoorthy Tau interacts with src-family non-receptor tyrosine kinases J Cell Sci 111 Pt 21 1998 3167 3177 (Pubitemid 28532427)
-
(1998)
Journal of Cell Science
, vol.111
, Issue.21
, pp. 3167-3177
-
-
Lee, G.1
Todd Newman, S.2
Gard, D.L.3
Band, H.4
Panchamoorthy, G.5
-
195
-
-
22244475384
-
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase
-
DOI 10.1523/JNEUROSCI.1487-05.2005
-
P. Derkinderen, T.M. Scales, D.P. Hanger, K.Y. Leung, H.L. Byers, and M.A. Ward Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase J Neurosci 25 2005 6584 6593 (Pubitemid 40995290)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.28
, pp. 6584-6593
-
-
Derkinderen, P.1
Scales, T.M.E.2
Hanger, D.P.3
Leung, K.-Y.4
Byers, H.L.5
Ward, M.A.6
Lenz, C.7
Price, C.8
Bird, I.N.9
Perera, T.10
Kellie, S.11
Williamson, R.12
Noble, W.13
Van Etten, R.A.14
Leroy, K.15
Brion, J.-P.16
Reynolds, C.H.17
Anderton, B.H.18
-
196
-
-
38349033673
-
The microtubule-associated protein tau is phosphorylated by Syk
-
T. Lebouvier, T.M. Scales, D.P. Hanger, R.L. Geahlen, B. Lardeux, and C.H. Reynolds The microtubule-associated protein tau is phosphorylated by Syk Biochim Biophys Acta 1783 2008 188 192
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 188-192
-
-
Lebouvier, T.1
Scales, T.M.2
Hanger, D.P.3
Geahlen, R.L.4
Lardeux, B.5
Reynolds, C.H.6
-
197
-
-
23744482703
-
Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates
-
DOI 10.1016/j.molbrainres.2005.04.015, PII S0169328X05001889
-
I.E. Vega, L. Cui, J.A. Propst, M.L. Hutton, G. Lee, and S.H. Yen Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates Brain Res Mol Brain Res 138 2005 135 144 (Pubitemid 41138032)
-
(2005)
Molecular Brain Research
, vol.138
, Issue.2
, pp. 135-144
-
-
Vega, I.E.1
Cui, L.2
Propst, J.A.3
Hutton, M.L.4
Lee, G.5
Yen, S.-H.6
-
198
-
-
77956504025
-
Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy
-
K. Bhaskar, G.A. Hobbs, S.H. Yen, and G. Lee Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy Neuropathol Appl Neurobiol 36 2010 462 477
-
(2010)
Neuropathol Appl Neurobiol
, vol.36
, pp. 462-477
-
-
Bhaskar, K.1
Hobbs, G.A.2
Yen, S.H.3
Lee, G.4
-
199
-
-
0036138048
-
Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-β peptide exposure: Involvement of Src family protein kinases
-
R. Williamson, T. Scales, B.R. Clark, G. Gibb, C.H. Reynolds, and S. Kellie Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases J Neurosci 22 2002 10 20 (Pubitemid 34033478)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.1
, pp. 10-20
-
-
Williamson, R.1
Scales, T.2
Clark, B.R.3
Gibb, G.4
Hugh Reynolds, C.5
Kellie, S.6
Bird, I.N.7
Varndell, I.M.8
Sheppard, P.W.9
Everall, I.10
Anderton, B.H.11
-
200
-
-
2442711560
-
Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice
-
DOI 10.1523/JNEUROSCI.0277-04.2004
-
J. Chin, J.J. Palop, G.-Q. Yu, N. Kojima, E. Masliah, and L. Mucke Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice J Neurosci 24 2004 4692 4697 (Pubitemid 38656624)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.19
, pp. 4692-4697
-
-
Chin, J.1
Palop, J.J.2
Yu, G.-Q.3
Kojima, N.4
Masliah, E.5
Mucke, L.6
-
201
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
M.P. Lambert, A.K. Barlow, B.A. Chromy, C. Edwards, R. Freed, and M. Liosatos Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins Proc Natl Acad Sci USA 95 1998 6448 6453
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
-
202
-
-
13644251548
-
Fyn kinase expression accompanies disease progression in Alzheimer's disease: Implications for its functional role
-
DOI 10.1016/j.neurobiolaging.2004.06.016
-
G.J. Ho, M. Hashimoto, A. Adame, M. Izu, M.F. Alford, and L.J. Thal Altered p59Fyn kinase expression accompanies disease progression in Alzheimer's disease: implications for its functional role Neurobiol Aging 26 2005 625 635 (Pubitemid 40228754)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.5
, pp. 625-635
-
-
Ho, G.J.1
Hashimoto, M.2
Adame, A.3
Izu, M.4
Alford, M.F.5
Thal, L.J.6
Hansen, L.A.7
Masliah, E.8
-
203
-
-
10544236116
-
The microtubule-associated protein tau is extensively modified with O- linked N-acetylglucosamine
-
DOI 10.1074/jbc.271.46.28741
-
C.S. Arnold, G.V. Johnson, R.N. Cole, D.L. Dong, M. Lee, and G.W. Hart The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine J Biol Chem 271 1996 28741 28744 (Pubitemid 26382566)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.46
, pp. 28741-28744
-
-
Shane Arnold, C.1
Johnson, G.V.W.2
Cole, R.N.3
Dong, D.L.-Y.4
Lee, M.5
Hart, G.W.6
-
204
-
-
0037163879
-
Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3β
-
DOI 10.1016/S0014-5793(02)03487-7, PII S0014579302034877
-
F. Liu, K. Iqbal, I. Grundke-Iqbal, and C.X. Gong Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta FEBS Lett 530 2002 209 214 (Pubitemid 35248213)
-
(2002)
FEBS Letters
, vol.530
, Issue.1-3
, pp. 209-214
-
-
Liu, F.1
Iqbal, K.2
Grundke-Iqbal, I.3
Gong, C.-X.4
-
205
-
-
33750940057
-
Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies
-
M.R. Reynolds, J.F. Reyes, Y. Fu, E.H. Bigio, A.L. Guillozet-Bongaarts, and R.W. Berry Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies J Neurosci 26 2006 10636 10645
-
(2006)
J Neurosci
, vol.26
, pp. 10636-10645
-
-
Reynolds, M.R.1
Reyes, J.F.2
Fu, Y.3
Bigio, E.H.4
Guillozet-Bongaarts, A.L.5
Berry, R.W.6
-
206
-
-
11144356089
-
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
-
DOI 10.1093/hmg/ddh083
-
L. Petrucelli, D. Dickson, K. Kehoe, J. Taylor, H. Snyder, and A. Grover CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation Hum Mol Genet 13 2004 703 714 (Pubitemid 38455958)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.7
, pp. 703-714
-
-
Petrucelli, L.1
Dickson, D.2
Kehoe, K.3
Taylor, J.4
Snyder, H.5
Grover, A.6
De Lucia, M.7
McGowan, E.8
Lewis, J.9
Prihar, G.10
Kim, J.11
Dillmann, W.H.12
Browne, S.E.13
Hall, A.14
Voellmy, R.15
Tsuboi, Y.16
Dawson, T.M.17
Wolozin, B.18
Hardy, J.19
Hutton, M.20
more..
-
207
-
-
1042266624
-
CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival
-
DOI 10.1074/jbc.M305838200
-
H. Shimura, D. Schwartz, S.P. Gygi, and K.S. Kosik CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival J Biol Chem 279 2004 4869 4876 (Pubitemid 38199082)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4869-4876
-
-
Shimura, H.1
Schwartz, D.2
Gygi, S.P.3
Kosik, K.S.4
-
208
-
-
5444239863
-
U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy
-
DOI 10.1111/j.1471-4159.2004.02713.x
-
S. Hatakeyama, M. Matsumoto, T. Kamura, M. Murayama, D.H. Chui, and E. Planel U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy J Neurochem 91 2004 299 307 (Pubitemid 39363429)
-
(2004)
Journal of Neurochemistry
, vol.91
, Issue.2
, pp. 299-307
-
-
Hatakeyama, S.1
Matsumoto, M.2
Kamura, T.3
Murayama, M.4
Chui, D.-H.5
Planel, E.6
Takahashi, R.7
Nakayama, K.I.8
Takashima, A.9
-
209
-
-
0027193036
-
Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments
-
DOI 10.1016/0896-6273(93)90063-W
-
M. Morishima-Kawashima, M. Hasegawa, K. Takio, M. Suzuki, K. Titani, and Y. Ihara Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments Neuron 10 1993 1151 1160 (Pubitemid 23194405)
-
(1993)
Neuron
, vol.10
, Issue.6
, pp. 1151-1160
-
-
Morishima-Kawashima, M.1
Hasegawa, M.2
Takio, K.3
Suzuki, M.4
Titani, K.5
Ihara, Y.6
-
210
-
-
33744950091
-
Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation
-
DOI 10.1074/jbc.M512786200
-
D. Cripps, S.N. Thomas, Y. Jeng, F. Yang, P. Davies, and A.J. Yang Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation J Biol Chem 281 2006 10825 10838 (Pubitemid 43855505)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.16
, pp. 10825-10838
-
-
Cripps, D.1
Thomas, S.N.2
Jeng, Y.3
Yang, F.4
Davies, P.5
Yang, A.J.6
-
211
-
-
33745959291
-
Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species
-
DOI 10.1523/JNEUROSCI.0746-06.2006
-
C.A. Dickey, M. Yue, W.L. Lin, D.W. Dickson, J.H. Dunmore, and W.C. Lee Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species J Neurosci 26 2006 6985 6996 (Pubitemid 44309866)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.26
, pp. 6985-6996
-
-
Dickey, C.A.1
Yue, M.2
Lin, W.-L.3
Dickson, D.W.4
Dunmore, J.H.5
Lee, W.C.6
Zehr, C.7
West, G.8
Cao, S.9
Clark, A.M.K.10
Caldwell, G.A.11
Caldwell, K.A.12
Eckman, C.13
Patterson, C.14
Hutton, M.15
Petrucelli, L.16
-
212
-
-
33744544785
-
Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and α-synuclein
-
DOI 10.1074/jbc.M510127200
-
V. Dorval, and P.E. Fraser Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein J Biol Chem 281 2006 9919 9924 (Pubitemid 43864524)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.15
, pp. 9919-9924
-
-
Dorval, V.1
Fraser, P.E.2
-
213
-
-
0033600242
-
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
-
DOI 10.1038/21650
-
P.J. Lu, G. Wulf, X.Z. Zhou, P. Davies, and K.P. Lu The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein Nature 399 1999 784 788 (Pubitemid 29293174)
-
(1999)
Nature
, vol.399
, Issue.6738
, pp. 784-788
-
-
Lu, P.-J.1
Wulf, G.2
Zhou, X.Z.3
Davies, P.4
Lu, K.P.5
-
214
-
-
1242307774
-
The Peptidyl Prolyl cis/trans-Isomerase Pin1 Recognizes the Phospho-Thr212-Pro213 Site on Tau
-
DOI 10.1021/bi035479x
-
C. Smet, A.V. Sambo, J.M. Wieruszeski, A. Leroy, I. Landrieu, and L. Buee The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau Biochemistry 43 2004 2032 2040 (Pubitemid 38233265)
-
(2004)
Biochemistry
, vol.43
, Issue.7
, pp. 2032-2040
-
-
Smet, C.1
Sambo, A.-V.2
Wieruszeski, J.-M.3
Leroy, A.4
Landrieu, I.5
Buee, L.6
Lippens, G.7
-
215
-
-
43049143027
-
Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy
-
DOI 10.1172/JCI34308
-
J. Lim, M. Balastik, T.H. Lee, K. Nakamura, Y.C. Liou, and A. Sun Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy J Clin Invest 118 2008 1877 1889 (Pubitemid 351632390)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.5
, pp. 1877-1889
-
-
Lim, J.1
Balastik, M.2
Lee, T.H.3
Nakamura, K.4
Liou, Y.-C.5
Sun, A.6
Finn, G.7
Pastorino, L.8
Lee, V.M.-Y.9
Lu, K.P.10
-
216
-
-
67650517850
-
Effect of Pin1 or Microtubule Binding on Dephosphorylation of FTDP-17 Mutant Tau
-
K. Yotsumoto, T. Saito, A. Asada, T. Oikawa, T. Kimura, and C. Uchida Effect of Pin1 or Microtubule Binding on Dephosphorylation of FTDP-17 Mutant Tau J Biol Chem 284 2009 16840 16847
-
(2009)
J Biol Chem
, vol.284
, pp. 16840-16847
-
-
Yotsumoto, K.1
Saito, T.2
Asada, A.3
Oikawa, T.4
Kimura, T.5
Uchida, C.6
-
217
-
-
0033638180
-
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
-
X.Z. Zhou, O. Kops, A. Werner, P.J. Lu, M. Shen, and G. Stoller Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins Mol Cell 6 2000 873 883
-
(2000)
Mol Cell
, vol.6
, pp. 873-883
-
-
Zhou, X.Z.1
Kops, O.2
Werner, A.3
Lu, P.J.4
Shen, M.5
Stoller, G.6
-
218
-
-
0043069764
-
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
-
DOI 10.1038/nature01832
-
Y.C. Liou, A. Sun, A. Ryo, X.Z. Zhou, Z.X. Yu, and H.K. Huang Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration Nature 424 2003 556 561 (Pubitemid 36975777)
-
(2003)
Nature
, vol.424
, Issue.6948
, pp. 556-561
-
-
Liou, Y.-C.1
Sun, A.2
Ryo, A.3
Zhou, X.Z.4
Yu, Z.-X.5
Huang, H.-K.6
Uchida, T.7
Bronson, R.8
Bing, G.9
Li, X.10
Hunter, T.11
Lu, K.P.12
-
219
-
-
0034682667
-
14-3-3zeta is an effector of tau protein phosphorylation
-
M. Hashiguchi, K. Sobue, and H.K. Paudel 14-3-3zeta is an effector of tau protein phosphorylation J Biol Chem 275 2000 25247 25254
-
(2000)
J Biol Chem
, vol.275
, pp. 25247-25254
-
-
Hashiguchi, M.1
Sobue, K.2
Paudel, H.K.3
-
220
-
-
1242337344
-
Zeta 14-3-3 protein favours the formation of human tau fibrillar polymers
-
DOI 10.1016/j.neulet.2003.12.049
-
F. Hernandez, R. Cuadros, and J. Avila Zeta 14-3-3 protein favours the formation of human tau fibrillar polymers Neurosci Lett 357 2004 143 146 (Pubitemid 38230951)
-
(2004)
Neuroscience Letters
, vol.357
, Issue.2
, pp. 143-146
-
-
Hernandez, F.1
Cuadros, R.2
Avila, J.3
-
221
-
-
0037631324
-
14-3-3 Connects glycogen synthase kinase-3β to tau within a brain microtubule-associated tau phosphorylation complex
-
DOI 10.1074/jbc.M211491200
-
A. Agarwal-Mawal, H.Y. Qureshi, P.W. Cafferty, Z. Yuan, D. Han, and R. Lin 14-3-3 connects glycogen synthase kinase-3 beta to tau within a brain microtubule-associated tau phosphorylation complex J Biol Chem 278 2003 12722 12728 (Pubitemid 36800034)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.15
, pp. 12722-12728
-
-
Agarwal-Mawal, A.1
Qureshi, H.Y.2
Cafferty, P.W.3
Yuan, Z.4
Han, D.5
Lin, R.6
Paudel, H.K.7
-
222
-
-
20644468811
-
14-3-3ζ does not increase GSK3β-mediated tau phosphorylation in cell culture models
-
DOI 10.1016/j.neulet.2005.04.101, PII S0304394005005926
-
T.A. Matthews, and G.V. Johnson 14-3-3Zeta does not increase GSK3beta-mediated tau phosphorylation in cell culture models Neurosci Lett 384 2005 211 216 (Pubitemid 40836002)
-
(2005)
Neuroscience Letters
, vol.384
, Issue.3
, pp. 211-216
-
-
Matthews, T.A.1
Johnson, G.V.W.2
-
223
-
-
33847181612
-
14-3-3zeta facilitates GSK3beta-catalyzed tau phosphorylation in HEK-293 cells by a mechanism that requires phosphorylation of GSK3beta on Ser9
-
T. Li, and H.K. Paudel 14-3-3zeta facilitates GSK3beta-catalyzed tau phosphorylation in HEK-293 cells by a mechanism that requires phosphorylation of GSK3beta on Ser9 Neurosci Lett 414 2007 203 208
-
(2007)
Neurosci Lett
, vol.414
, pp. 203-208
-
-
Li, T.1
Paudel, H.K.2
-
224
-
-
57249108291
-
Phosphorylation of tau at Ser214 mediates its interaction with 14-3-3 protein: Implications for the mechanism of tau aggregation
-
G. Sadik, T. Tanaka, K. Kato, H. Yamamori, B.N. Nessa, and T. Morihara Phosphorylation of tau at Ser214 mediates its interaction with 14-3-3 protein: implications for the mechanism of tau aggregation J Neurochem 108 2009 33 43
-
(2009)
J Neurochem
, vol.108
, pp. 33-43
-
-
Sadik, G.1
Tanaka, T.2
Kato, K.3
Yamamori, H.4
Nessa, B.N.5
Morihara, T.6
-
225
-
-
69249212121
-
Phosphorylation of more than one site is required for tight interaction of human tau protein with 14-3-3zeta
-
N.N. Sluchanko, A.S. Seit-Nebi, and N.B. Gusev Phosphorylation of more than one site is required for tight interaction of human tau protein with 14-3-3zeta FEBS Lett 583 2009 2739 2742
-
(2009)
FEBS Lett
, vol.583
, pp. 2739-2742
-
-
Sluchanko, N.N.1
Seit-Nebi, A.S.2
Gusev, N.B.3
-
226
-
-
64949087565
-
Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3zeta protein
-
G. Sadik, T. Tanaka, K. Kato, K. Yanagi, T. Kudo, and M. Takeda Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3zeta protein Biochem Biophys Res Commun 383 2009 37 41
-
(2009)
Biochem Biophys Res Commun
, vol.383
, pp. 37-41
-
-
Sadik, G.1
Tanaka, T.2
Kato, K.3
Yanagi, K.4
Kudo, T.5
Takeda, M.6
-
227
-
-
77953524779
-
Tau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding
-
C.J. Leugers, and G. Lee Tau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding J Biol Chem 285 2010 19125 19134
-
(2010)
J Biol Chem
, vol.285
, pp. 19125-19134
-
-
Leugers, C.J.1
Lee, G.2
-
228
-
-
0026787130
-
Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain
-
M. Hasegawa, M. Morishima-Kawashima, K. Takio, M. Suzuki, K. Titani, and Y. Ihara Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain J Biol Chem 267 1992 17047 17054
-
(1992)
J Biol Chem
, vol.267
, pp. 17047-17054
-
-
Hasegawa, M.1
Morishima-Kawashima, M.2
Takio, K.3
Suzuki, M.4
Titani, K.5
Ihara, Y.6
-
229
-
-
0031685160
-
Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease
-
DOI 10.1016/S0197-4580(98)00071-2, PII S0197458098000712
-
I. Vincent, J.H. Zheng, D.W. Dickson, Y. Kress, and P. Davies Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease Neurobiol Aging 19 1998 287 296 (Pubitemid 28470596)
-
(1998)
Neurobiology of Aging
, vol.19
, Issue.4
, pp. 287-296
-
-
Vincent, I.1
Zheng, J.-H.2
Dickson, D.W.3
Kress, Y.4
Davies, P.5
-
230
-
-
12244279939
-
Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease
-
DOI 10.1016/S0169-328X(02)00488-6, PII S0169328X02004886
-
J.J. Pei, H. Braak, W.L. An, B. Winblad, R.F. Cowburn, and K. Iqbal Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease Brain Res Mol Brain Res 109 2002 45 55 (Pubitemid 36078372)
-
(2002)
Molecular Brain Research
, vol.109
, Issue.1-2
, pp. 45-55
-
-
Pei, J.-J.1
Braak, H.2
An, W.-L.3
Winblad, B.4
Cowburn, R.F.5
Iqbal, K.6
Grundke-Iqbal, I.7
-
231
-
-
0035094403
-
Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration
-
I. Ferrer, R. Blanco, M. Carmona, R. Ribera, E. Goutan, and B. Puig Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration Brain Pathol 11 2001 144 158 (Pubitemid 32198842)
-
(2001)
Brain Pathology
, vol.11
, Issue.2
, pp. 144-158
-
-
Ferrer, I.1
Blanco, R.2
Carmona, M.3
Ribera, R.4
Goutan, E.5
Puig, B.6
Rey, M.J.7
Cardozo, A.8
Vinals, F.9
Ribalta, T.10
-
232
-
-
0033516947
-
Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation
-
G. Perry, H. Roder, A. Nunomura, A. Takeda, A.L. Friedlich, and X. Zhu Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation Neuroreport 10 1999 2411 2415 (Pubitemid 29367948)
-
(1999)
NeuroReport
, vol.10
, Issue.11
, pp. 2411-2415
-
-
Perry, G.1
Roder, H.2
Nunomura, A.3
Takeda, A.4
Friedlich, A.L.5
Zhu, X.6
Raina, A.K.7
Holbrook, N.8
Siedlak, S.L.9
Harris, P.L.R.10
Smith, M.A.11
-
233
-
-
49649119504
-
Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases
-
C.H. Reynolds, C.J. Garwood, S. Wray, C. Price, S. Kellie, and T. Perera Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases J Biol Chem 283 2008 18177 18186
-
(2008)
J Biol Chem
, vol.283
, pp. 18177-18186
-
-
Reynolds, C.H.1
Garwood, C.J.2
Wray, S.3
Price, C.4
Kellie, S.5
Perera, T.6
-
234
-
-
0032484582
-
Tau complexes with phospholipase C-γ in situ
-
S.M. Jenkins, and G.V. Johnson Tau complexes with phospholipase C-gamma in situ Neuroreport 9 1998 67 71 (Pubitemid 28046656)
-
(1998)
NeuroReport
, vol.9
, Issue.1
, pp. 67-71
-
-
Jenkins, S.M.1
Johnson, G.V.W.2
-
235
-
-
0001169160
-
Activation of phospholipase C-γ by the concerted action of tau proteins and arachidonic acid
-
DOI 10.1074/jbc.271.31.18342
-
S.C. Hwang, D.Y. Jhon, Y.S. Bae, J.H. Kim, and S.G. Rhee Activation of phospholipase C-gamma by the concerted action of tau proteins and arachidonic acid J Biol Chem 271 1996 18342 18349 (Pubitemid 26322687)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.31
, pp. 18342-18349
-
-
Hwang, S.C.1
Jhon, D.-Y.2
Bae, Y.S.3
Kim, J.H.4
Rhee, S.G.5
-
236
-
-
27444437758
-
Disease-related modifications in tau affect the interaction between Fyn and tau
-
DOI 10.1074/jbc.M505895200
-
K. Bhaskar, S.H. Yen, and G. Lee Disease-related modifications in tau affect the interaction between Fyn and Tau J Biol Chem 280 2005 35119 35125 (Pubitemid 41532698)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.42
, pp. 35119-35125
-
-
Bhaskar, K.1
Yen, S.-H.2
Lee, G.3
-
237
-
-
0035955702
-
Binding of Fyn to MAP-2c through an SH3 binding domain. Regulation of the interaction by ERK2
-
S.P. Zamora-Leon, G. Lee, P. Davies, and B. Shafit-Zagardo Binding of Fyn to MAP-2c through an SH3 binding domain. Regulation of the interaction by ERK2 J Biol Chem 276 2001 39950 39958
-
(2001)
J Biol Chem
, vol.276
, pp. 39950-39958
-
-
Zamora-Leon, S.P.1
Lee, G.2
Davies, P.3
Shafit-Zagardo, B.4
-
238
-
-
57049139853
-
Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone
-
M. Sarkar, J. Kuret, and G. Lee Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone J Neurosci Res 86 2008 2763 2773
-
(2008)
J Neurosci Res
, vol.86
, pp. 2763-2773
-
-
Sarkar, M.1
Kuret, J.2
Lee, G.3
-
239
-
-
37549025063
-
BAG-1 associates with Hsc70.Tau complex and regulates the proteasomal degradation of Tau protein
-
E. Elliott, P. Tsvetkov, and I. Ginzburg BAG-1 associates with Hsc70.Tau complex and regulates the proteasomal degradation of Tau protein J Biol Chem 282 2007 37276 37284
-
(2007)
J Biol Chem
, vol.282
, pp. 37276-37284
-
-
Elliott, E.1
Tsvetkov, P.2
Ginzburg, I.3
-
240
-
-
70349987102
-
Tau fragmentation, aggregation and clearance: The dual role of lysosomal processing
-
Y. Wang, M. Martinez-Vicente, U. Kruger, S. Kaushik, E. Wong, and E.M. Mandelkow Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing Hum Mol Genet 18 2009 4153 4170
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4153-4170
-
-
Wang, Y.1
Martinez-Vicente, M.2
Kruger, U.3
Kaushik, S.4
Wong, E.5
Mandelkow, E.M.6
-
241
-
-
77954571538
-
A caspase cleaved form of tau is preferentially degraded through the autophagy pathway
-
P.J. Dolan, and G.V. Johnson A caspase cleaved form of tau is preferentially degraded through the autophagy pathway J Biol Chem 285 2010 21978 21987
-
(2010)
J Biol Chem
, vol.285
, pp. 21978-21987
-
-
Dolan, P.J.1
Johnson, G.V.2
-
242
-
-
33646246733
-
HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites
-
DOI 10.1096/fj.05-5343fje
-
C.A. Dickey, J. Dunmore, B. Lu, J.W. Wang, W.C. Lee, and A. Kamal HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites FASEB J 20 2006 753 755 (Pubitemid 46671204)
-
(2006)
FASEB Journal
, vol.20
, Issue.6
, pp. 753-755
-
-
Dickey, C.A.1
Dunmore, J.2
Lu, B.3
Wang, J.-W.4
Lee, W.C.5
Kamal, A.6
Burrows, F.7
Eckman, C.8
Hutton, M.9
Petrucelli, L.10
-
243
-
-
33847369469
-
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
-
DOI 10.1172/JCI29715
-
C.A. Dickey, A. Kamal, K. Lundgren, N. Klosak, R.M. Bailey, and J. Dunmore The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins J Clin Invest 117 2007 648 658 (Pubitemid 46348523)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.3
, pp. 648-658
-
-
Dickey, C.A.1
Kamal, A.2
Lundgren, K.3
Klosak, N.4
Bailey, R.M.5
Dunmore, J.6
Ash, P.7
Shoraka, S.8
Zlatkovic, J.9
Eckman, C.B.10
Patterson, C.11
Dickson, D.W.12
Nahman Jr., N.S.13
Hutton, M.14
Burrows, F.15
Petrucelli, L.16
-
244
-
-
35848942592
-
Molecular chaperone-mediated tau protein metabolism counteracts the formation of granular tau oligomers in human brain
-
DOI 10.1002/jnr.21417
-
N. Sahara, S. Maeda, Y. Yoshiike, T. Mizoroki, S. Yamashita, and M. Murayama Molecular chaperone-mediated tau protein metabolism counteracts the formation of granular tau oligomers in human brain J Neurosci Res 85 2007 3098 3108 (Pubitemid 350057365)
-
(2007)
Journal of Neuroscience Research
, vol.85
, Issue.14
, pp. 3098-3108
-
-
Sahara, N.1
Maeda, S.2
Yoshiike, Y.3
Mizoroki, T.4
Yamashita, S.5
Murayama, M.6
Park, J.-M.7
Saito, Y.8
Murayama, S.9
Takashima, A.10
-
246
-
-
0029993245
-
Tau as a nucleolar protein in human nonneural cells in vitro and in vivo
-
DOI 10.1007/s004120050155
-
V.C. Thurston, R.P. Zinkowski, and L.I. Binder Tau as a nucleolar protein in human nonneural cells in vitro and in vivo Chromosoma 105 1996 20 30 (Pubitemid 26248742)
-
(1996)
Chromosoma
, vol.105
, Issue.1
, pp. 20-30
-
-
Thurston, V.C.1
Zinkowski, R.P.2
Binder, L.I.3
-
247
-
-
0023505501
-
Phosphorylation determines two distinct species of Tau in the central nervous system
-
S.C. Papasozomenos, and L.I. Binder Phosphorylation determines two distinct species of Tau in the central nervous system Cell Motil Cytoskeleton 8 1987 210 226
-
(1987)
Cell Motil Cytoskeleton
, vol.8
, pp. 210-226
-
-
Papasozomenos, S.C.1
Binder, L.I.2
-
248
-
-
0037454755
-
Evidence of a balance between phosphorylation and O-GlcNAc glycosylation of Tau proteins - A role in nuclear localization
-
DOI 10.1016/S0304-4165(02)00477-4
-
T. Lefebvre, S. Ferreira, L. Dupont-Wallois, T. Bussiere, M.J. Dupire, and A. Delacourte Evidence of a balance between phosphorylation and O-GlcNAc glycosylation of Tau proteins - a role in nuclear localization Biochim Biophys Acta 1619 2003 167 176 (Pubitemid 36078354)
-
(2003)
Biochimica et Biophysica Acta - General Subjects
, vol.1619
, Issue.2
, pp. 167-176
-
-
Lefebvre, T.1
Ferreira, S.2
Dupont-Wallois, L.3
Bussiere, T.4
Dupire, M.-J.5
Delacourte, A.6
Michalski, J.-C.7
Caillet-Boudin, M.-L.8
-
249
-
-
14244251724
-
Tau protein binds single-stranded DNA sequence specifically - The proof obtained in vitro with non-equilibrium capillary electrophoresis of equilibrium mixtures
-
DOI 10.1016/j.febslet.2005.01.032
-
S.M. Krylova, M. Musheev, R. Nutiu, Y. Li, G. Lee, and S.N. Krylov Tau protein binds single-stranded DNA sequence specifically - the proof obtained in vitro with non-equilibrium capillary electrophoresis of equilibrium mixtures FEBS Lett 579 2005 1371 1375 (Pubitemid 40289182)
-
(2005)
FEBS Letters
, vol.579
, Issue.6
, pp. 1371-1375
-
-
Krylova, S.M.1
Musheev, M.2
Nutiu, R.3
Li, Y.4
Lee, G.5
Krylov, S.N.6
-
250
-
-
47249111324
-
A new function of microtubule-associated protein tau: Involvement in chromosome stability
-
G. Rossi, L. Dalpra, F. Crosti, S. Lissoni, F.L. Sciacca, and M. Catania A new function of microtubule-associated protein tau: involvement in chromosome stability Cell Cycle 7 2008 1788 1794 (Pubitemid 351988745)
-
(2008)
Cell Cycle
, vol.7
, Issue.12
, pp. 1788-1794
-
-
Rossi, G.1
Dalpra, L.2
Crosti, F.3
Lissoni, S.4
Sciacca, F.L.5
Catania, M.6
Di Fede, G.7
Mangieri, M.8
Giaccone, G.9
Croci, D.10
Tagliavini, F.11
-
251
-
-
0040141570
-
Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments
-
DOI 10.1074/jbc.M000389200
-
T. Maas, J. Eidenmuller, and R. Brandt Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments J Biol Chem 275 2000 15733 15740 (Pubitemid 30366871)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.21
, pp. 15733-15740
-
-
Maas, T.1
Eidenmuller, J.2
Brandt, R.3
-
252
-
-
17544393297
-
Tau dephosphorylation at Tau-1 site correlates with its association to cell membrane
-
DOI 10.1023/A:1007583214722
-
M. Arrasate, M. Perez, and J. Avila Tau dephosphorylation at tau-1 site correlates with its association to cell membrane Neurochem Res 25 2000 43 50 (Pubitemid 30074274)
-
(2000)
Neurochemical Research
, vol.25
, Issue.1
, pp. 43-50
-
-
Arrasate, M.1
Perez, M.2
Avila, J.3
-
253
-
-
0029835019
-
A spatial gradient of tau protein phosphorylation in nascent axons
-
J.W. Mandell, and G.A. Banker A spatial gradient of tau protein phosphorylation in nascent axons J Neurosci 16 1996 5727 5740 (Pubitemid 26293396)
-
(1996)
Journal of Neuroscience
, vol.16
, Issue.18
, pp. 5727-5740
-
-
Mandell, J.W.1
Banker, G.A.2
-
254
-
-
0036469248
-
Process outgrowth of oligodendrocytes is promoted by interaction of Fyn kinase with the cytoskeletal protein Tau
-
C. Klein, E.M. Kramer, A.M. Cardine, B. Schraven, R. Brandt, and J. Trotter Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau J Neurosci 22 2002 698 707 (Pubitemid 34141750)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.3
, pp. 698-707
-
-
Klein, C.1
Kramer, E.-M.2
Cardine, A.-M.3
Schraven, B.4
Brandt, R.5
Trotter, J.6
-
255
-
-
11144356498
-
Dimeric Amyloid β Protein Rapidly Accumulates in Lipid Rafts followed by Apolipoprotein E and Phosphorylated Tau Accumulation in the Tg2576 Mouse Model of Alzheimer's Disease
-
DOI 10.1523/JNEUROSCI.5543-03.2004
-
T. Kawarabayashi, M. Shoji, L.H. Younkin, L. Wen-Lang, D.W. Dickson, and T. Murakami Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease J Neurosci 24 2004 3801 3809 (Pubitemid 38509410)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.15
, pp. 3801-3809
-
-
Kawarabayashi, T.1
Shoji, M.2
Younkin, L.H.3
Wen-Lang, L.4
Dickson, D.W.5
Murakami, T.6
Matsubara, E.7
Abe, K.8
Ashe, K.H.9
Younkin, S.G.10
-
256
-
-
43249114144
-
Membrane-bound β-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism
-
DOI 10.1096/fj.07-9766com
-
R. Williamson, A. Usardi, D.P. Hanger, and B.H. Anderton Membrane-bound beta-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism FASEB J 22 2008 1552 1559 (Pubitemid 351656795)
-
(2008)
FASEB Journal
, vol.22
, Issue.5
, pp. 1552-1559
-
-
Williamson, R.1
Usardi, A.2
Hanger, D.P.3
Anderton, B.H.4
-
257
-
-
58849084518
-
Tau phosphorylation by cdk5 and Fyn in response to amyloid peptide Abeta (25-35): Involvement of lipid rafts
-
P. Hernandez, G. Lee, M. Sjoberg, and R.B. Maccioni Tau phosphorylation by cdk5 and Fyn in response to amyloid peptide Abeta (25-35): involvement of lipid rafts J Alzheimers Dis 16 2009 149 156
-
(2009)
J Alzheimers Dis
, vol.16
, pp. 149-156
-
-
Hernandez, P.1
Lee, G.2
Sjoberg, M.3
MacCioni, R.B.4
-
258
-
-
77049123465
-
Interneuronal transfer of human tau between lamprey central neurons in situ
-
in press
-
W.H. Kim, S. Lee, C. Jung, A. Ahmed, G. Lee, and G.F. Hall Interneuronal transfer of human tau between lamprey central neurons in situ J Alzheimers Dis 19 2010 647 664 in press
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 647-664
-
-
Kim, W.H.1
Lee, S.2
Jung, C.3
Ahmed, A.4
Lee, G.5
Hall, G.F.6
-
259
-
-
41149111293
-
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
-
A. Gomez-Ramos, M. Diaz-Hernandez, A. Rubio, M.T. Miras-Portugal, and J. Avila Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells Mol Cell Neurosci 37 2008 673 681
-
(2008)
Mol Cell Neurosci
, vol.37
, pp. 673-681
-
-
Gomez-Ramos, A.1
Diaz-Hernandez, M.2
Rubio, A.3
Miras-Portugal, M.T.4
Avila, J.5
-
260
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
F. Clavaguera, T. Bolmont, R.A. Crowther, D. Abramowski, S. Frank, and A. Probst Transmission and spreading of tauopathy in transgenic mouse brain Nat Cell Biol 11 2009 909 913
-
(2009)
Nat Cell Biol
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
-
261
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
B. Frost, R.L. Jacks, and M.I. Diamond Propagation of tau misfolding from the outside to the inside of a cell J Biol Chem 284 2009 12845 12852
-
(2009)
J Biol Chem
, vol.284
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
262
-
-
53149103944
-
Truncated Tau with the Fyn-binding domain and without the microtubule-binding domain hinders the myelinating capacity of an oligodendrocyte cell line
-
A. Belkadi, and P. LoPresti Truncated Tau with the Fyn-binding domain and without the microtubule-binding domain hinders the myelinating capacity of an oligodendrocyte cell line J Neurochem 107 2008 351 360
-
(2008)
J Neurochem
, vol.107
, pp. 351-360
-
-
Belkadi, A.1
Lopresti, P.2
-
263
-
-
33751218015
-
Tau-dependent microtubule disassembly initiated by prefibrillar β-amyloid
-
DOI 10.1083/jcb.200605187
-
M.E. King, H.M. Kan, P.W. Baas, A. Erisir, C.G. Glabe, and G.S. Bloom Tau-dependent microtubule disassembly initiated by prefibrillar beta-amyloid J Cell Biol 175 2006 541 546 (Pubitemid 44790607)
-
(2006)
Journal of Cell Biology
, vol.175
, Issue.4
, pp. 541-546
-
-
King, M.E.1
Kan, H.-M.2
Baas, P.W.3
Erisir, A.4
Glabe, C.G.5
Bloom, G.S.6
-
264
-
-
77955322042
-
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models
-
L.M. Ittner, Y.D. Ke, F. Delerue, M. Bi, A. Gladbach, and J. van Eersel Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models Cell 142 2010 387 397
-
(2010)
Cell
, vol.142
, pp. 387-397
-
-
Ittner, L.M.1
Ke, Y.D.2
Delerue, F.3
Bi, M.4
Gladbach, A.5
Van Eersel, J.6
-
265
-
-
3142695169
-
Tau isoforms which contain the domain encoded by exon 6 and their role in neurite elongation
-
M.H. Luo, M.L. Leski, and A. Andreadis Tau isoforms which contain the domain encoded by exon 6 and their role in neurite elongation J Cell Biochem 91 2004 880 895
-
(2004)
J Cell Biochem
, vol.91
, pp. 880-895
-
-
Luo, M.H.1
Leski, M.L.2
Andreadis, A.3
-
266
-
-
20044370830
-
The generation of a 17 kDa neurotoxic fragment: An alternative mechanism by which tau mediates β-amyloid-induced neurodegeneration
-
DOI 10.1523/JNEUROSCI.1125-05.2005
-
S.Y. Park, and A. Ferreira The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration J Neurosci 25 2005 5365 5375 (Pubitemid 40770916)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.22
, pp. 5365-5375
-
-
Park, S.-Y.1
Ferreira, A.2
-
267
-
-
65549150954
-
Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity
-
A.M. Nicholson, and A. Ferreira Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity J Neurosci 29 2009 4640 4651
-
(2009)
J Neurosci
, vol.29
, pp. 4640-4651
-
-
Nicholson, A.M.1
Ferreira, A.2
-
268
-
-
61349120815
-
Structural polymorphism of 441-residue tau at single residue resolution
-
M.D. Mukrasch, S. Bibow, J. Korukottu, S. Jeganathan, J. Biernat, and C. Griesinger Structural polymorphism of 441-residue tau at single residue resolution PLoS Biol 7 2009 e34
-
(2009)
PLoS Biol
, vol.7
, pp. 34
-
-
Mukrasch, M.D.1
Bibow, S.2
Korukottu, J.3
Jeganathan, S.4
Biernat, J.5
Griesinger, C.6
-
269
-
-
58149463424
-
MTOR-dependent signalling in Alzheimer's disease
-
J.J. Pei, and J. Hugon mTOR-dependent signalling in Alzheimer's disease J Cell Mol Med 12 2008 2525 2532
-
(2008)
J Cell Mol Med
, vol.12
, pp. 2525-2532
-
-
Pei, J.J.1
Hugon, J.2
|