Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation

NeuroReport

Volumn 10, Issue 11, 1999, Pages 2411-2415

  Perry, George ^a   Roder, Hanno ^a,b   Nunomura, Akihiko ^a,c   Takeda, Atsushi ^a   Friedlich, Avi L ^a   Zhu, Xiongwei ^a   Raina, Arun K ^a   Holbrook, Nikki ^d   Siedlak, Sandra L ^a   Harris, Peggy L R ^a   Smith, Mark A ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b NAP AG   (Germany)

^c ASAHIKAWA MEDICAL COLLEGE   (Japan)

^d NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Alzheimer disease; ERK2; MAP kinase; PHF ; Phosphorylation

Indexed keywords

CYTOSKELETON PROTEIN; NEUROFILAMENT PROTEIN; PHOSPHOTRANSFERASE;

ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPATHOLOGY; ENZYME ACTIVATION; ENZYME REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; OXIDATIVE STRESS; PHOSPHORYLATION; PRIORITY JOURNAL;

EID: 0033516947     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-199908020-00035     Document Type: Article

References (19)

1. 1. Smith MA. Int Rev Neurobiol 42, 1-54 (1998).
2. 2 Hirai K, Smith MA, Wade R and Perry G. Neurobiol Aging 19 (Suppl 4S), S4-S5 (1998).
3. 3. Guyton KZ, Liu Y, Gorospe M et al. J Biol Chem 271, 4138-4142 (1996).
4. 4. Roder HM and Ingram VM. J Neurosci 11, 3323-3343 (1991).
5. 5. Drewes G, Lichtenberg-Kraag B, Döring F et al. EMBO J 11, 2131-2138 (1992).
6. 6. Roder HM, Hoffman FJ and Schröder W. J Neurochem 64, 2203-2212 (1995).
7. 7. Roder HM, Fracasso RP, Hoffman FJ et al. J Biol Chem 272, 4509-4515 (1997).
8. 8. Veeranna, Amin ND, Ahn NG et al. J Neurosci 18, 4008-4021 (1998).
9. 9. Khachaturian ZS. Arch Neurol 42, 1097-1105 (1985).
10. 10. Miffa SS, Heyman A, McKeel D et al. Neurology 41, 479-486 (1991).
11. 11. Smith MA, Kutty RK, Richey PL et al. Am J Pathol 145, 42-47 (1994).
12. 12. Nunomura A, Perry G, Pappolla MA et al. J Neurosci 19, 1959-1964 (1898).
13. 13. Sternberger LA. Immunocytochemistry, 3rd edn, Wiley, New York, 1980.
14. 14. Trojanowski JQ, Mawal-Dewan M, Schmidt ML et al. Brain Res 618, 333-337 (1993).
15. 15. Hyman BT, Elvhage TE and Reiter J. Am J Pathol 144, 565-572 (1994).
16. 16. Luo Y, Bond JD and Ingram VM. Proc Natl Acad Sci USA 94, 9705-9710 (1997).
17. 17. Perry G, Nunomura A and Smith MA. Nature Med 4, 897-898 (1998).
18. 18. McShea A, Harris PLR, Webster KR et al. Am J Pathol 150, 1933-1939 (1997).
19. 19. Raina AK, Monteiro MJ, McShea A and Smith MA. Int J Exp Pathol 80, 71-76 (1999).