Inability of tau to properly regulate neuronal microtubule dynamics: A loss-of-function mechanism by which tau might mediate neuronal cell death

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1739, Issue 2, 2005, Pages 268-279

  Feinstein, Stuart C ^a   Wilson, Leslie ^a  

^a Univ C   (United States)

Author keywords

Alzheimer's disease; Cytoskeleton; FTDP 17; Loss of function; Microtubule dynamics; Tau

Indexed keywords

AMINO ACID; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; COLCHICINE; MICROTUBULE ASSOCIATED PROTEIN; PACLITAXEL; TAU PROTEIN;

ALZHEIMER DISEASE; BRAIN NERVE CELL; CELL VIABILITY; CHROMOSOME 17; DEMENTIA; DRUG MECHANISM; DRUG PROTEIN BINDING; FRONTOTEMPORAL DEMENTIA; MICROTUBULE; MISSENSE MUTATION; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; REVIEW; RNA SPLICING;

CELL DEATH; COLCHICINE; DEMENTIA; HUMANS; MICROTUBULES; MODELS, BIOLOGICAL; NERVE DEGENERATION; NEURONS; PACLITAXEL; TAU PROTEINS;

EID: 10944256690     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2004.07.002     Document Type: Review

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