Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

Biochemistry

Volumn 38, Issue 12, 1999, Pages 3549-3558

  Schneider, A ^a   Biernat, J ^a   Von Bergen, M ^a   Mandelkow, E ^a   Mandelkow, E M ^a  

^a MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; TAU PROTEIN;

ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; MICROTUBULE ASSEMBLY; NONHUMAN; PAIRED HELICAL FILAMENT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ALZHEIMER DISEASE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HUMANS; MICROTUBULES; NEUROFIBRILLARY TANGLES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; REPETITIVE SEQUENCES, NUCLEIC ACID; SERINE; TAU PROTEINS;

EID: 0033596946     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981874p     Document Type: Article

References (67)

1. Selkoe, D. (1998) Trends in Cell Biol. 8, 447-453.
2. Mandelkow, E.-M., and Mandelkow, E. (1998) Trends Cell Biol. 8, 425-427.
3. Braak, H., and Braak, E. (1991) Acta Neuropathol. 82, 239-259.
4. Gomez-Isla T., Hollister, R., West, H., Mui, S., Growdon, J. H., Petersen, R. C., Parisi, J. E., and Hyman, B. T. (1997) Ann. Neurol. 41, 17-24.
5. Butner, K. A., and Kirschner, M. W. (1991) J. Cell Biol. 115, 717-730.
6. Gustke, N., Trinczek, B., Biernat, J., Mandelkow, E.-M., and Mandelkow, E. (1994) Biochemistry 33, 9511-9522.
7. Grundke-Iqbal, I., Iqbal, K., Tung, Y., Quinlan, M., Wisniewski, H., and Binder, L. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 4913-4917.
8. Morishima-Kawashima, M., Hasegawa, M., Takio, K., Suzuki, M., Yoshida, H., Titani, K., and Ihara, Y. (1995) J. Biol. Chem. 270, 823-829.
9. Terry, R. D. (1996) J. Neuropath. Exp. Neurol. 55, 1023-1025.
10. Jarrett, J. T., and Lansbury, P. T. (1993) Cell 73, 1055-1058.
11. Wille, H., Drewes, G., Biemat, J., Mandelkow, E.-M., and Mandelkow, E. (1992) J. Cell Biol. 118, 573-584.
12. Schweers, O., Mandelkow, E.-M., Biernat, J., and Mandelkow, E. (1995) Proc. Natl. Acad Sci. U.S.A. 92, 8463-8467.
13. Wilson, D., and Binder, L. I. (1997) Am. J. Pathol. 150, 2181-2195.
14. Perez, M., Valpuesta, J. M., Medina, M., Degarcini, E. M., and Avila, J. (1996) J. Neurochem. 67, 1183-1190.
15. Goedert, M., Jakes, R., Spillantini, M., Hasegawa, M., Smith, M., and Crowther, R. (1996) Nature 383, 550-553.
16. Kampers, T., Friedhoff, P., Biernat, J., Mandelkow, E.-M., and Mandelkow, E. (1996) FEBS Lett. 399, 344-349.
17. Hasegawa, M., Crowther, R. A., Jakes, B., and Goedert, M. (1997) J. Biol. Chem. 272, 33118-33124.
18. Friedhoff, P., Schneider, A., Mandelkow, E.-M., and Mandelkow, E. (1998) Biochemistry 37, 10223-10230.
19. Trojanowski, J., and Lee, V. M. Y. (1995) FASEB J. 9, 1570-1576.
20. Johnson, G., and Jenkins, S. (1996) Alzheimer's Dis. Rev. 1, 38-54.
21. Friedhoff, P., and Mandelkow, E. (1999) Tau Protein, in Guidebook to the Cytoskeletal and Motor Proteins, Kreis, T., Vale, R., Eds., Oxford University Press (in press).
22. Biernat, J., Gustke, N., Drewes, G., Mandelkow, E.-M., and Mandelkow, E. (1993) Neuron II, 153-163.
23. Drewes, G., Ebneth, A., Preuss, U., Mandelkow, E.-M., and Mandelkow, E. (1997) Cell 89, 297-308.
24. Illenberger, S., Zheng-Fischhöfer, Q., Preuss, U., Stamer, K., Baumann, K., Trinczek, B., Biernat, J., Godemann, R., Mandelkow, E.-M., Godemann, R., and Mandelkow, E. (1998) J. Biol. Cell 9, 1495-1512.
25. Brandt, R., Lee, G., Teplow, D., Shalloway, D., and Abdelghany, M. (1994) J. Biol. Chem. 269, 11776-11782.
26. Jenkins, S. M., and Johnson, G. V. W. (1997) Brain Res. 767, 305-313.
27. Goedert, M., Spillantini, M., Potier, M., Ulrich, J., and Crowther, R. (1989) EMBO J. 8, 393-399.
28. Song, J. S., and Yang, S. D. (1995) J. Protein Chem. 14, 95-105.
29. Moreno, F. J., Munoz-Montano, J. R., and Avila, J. (1996) Mol. Cell. Biochem. 165, 47-54.
30. Boyle, W. J., van der Geer, P., and Hunter, T. (1991) Methods Enzymol. 201, 110-149.
31. Illenberger, S., Drewes, G., Trinczek, B., Biernat, J., Meyer, H. E., Olmsted, J. B., Mandelkow, E. M., and Mandelkow, E. (1996) Biol. Chem. 271, 10834-10843.
32. Wischik, C., Novak, M., Thogersen, H., Edwards, P., Runswick, M., Jakes, R., Walker, J., Milstein, C., Roth, M., and Klug, A. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 4506-4510.
33. Bancher, C., Grundke-Iqbal, I., Iqbal, K., Fried, V., Smith, H., and Wisniewski, H. (1991) Brain Res. 539, 11-18.
34. Braak, E., Braak, H., and Mandelkow, E.-M. (1994) Acta Neuropath. 87, 554-567.
35. Drewes, G., Trinczek, B., Illenberger, S., Biemat, J., Schmitt-Ulms, G., Meyer, H. E., Mandelkow, E. M., and Mandelkow, E. (1995) J. Biol. Chem. 270, 7679-7688.
36. Zheng-Fischhöfer, Q., Biernat, J., Mandelkow, E.-M., Illenberger, S., Godemann, R., and Mandelkow, E. (1998) Eur. J. Biochem. 252, 542-552.
37. Hoffmann, R., Lee, V. M. Y., Leight, S., Varga, I., and Otvos, L. (1997) Biochemistry 36, 8114-8124.
38. Gross, U. (1996) Ph.D. Thesis, University of Hamburg.
39. Dickson, D., Ksiezak-Reding, H., Liu, W., Davies, P., Crowe, A., and Yen, S. H. (1992) Acta Neuropath. 84, 596-605.
40. Seubert, P., Mawaldewan, M., Barbour, R., Jakes, R., Goedert, M., Johnson, G. V. W., Litersky, J., Schenk, D., Lieberburg, I., Trojanowski, J., and Lee, V. M. Y. (1995) J. Biol. Chem. 270, 18917-18922.
41. Arriagada, P. V., Growdon, J. H., Hedley-Whyte, E., and Hyman, B. T. (1992) Neurology 42, 631-639.
42. Kosik, K. S. (1993) Brain Pathol. 3, 39-43.
43. Mandelkow, E.-M., Biernat, J., Drewes, G., Gustke, N., Trinevek, B., and Mandelkow, E. (1995) Neurobiol. Aging 16, 355-362.
44. Vigo-Pelfrey, C., Seubert, P., Barbour, R., Blomquist, C., Lee, M., Lee, D., Coria, F., Chang, L., Miller, B., Lieberburg, I., and Schenk, D. (1995) Neurology 45, 788-793.
45. Hanemaaijer, R., and Ginzburg, I. (1991) J. Neurosci. Res. 30, 163-171.
46. Kosik, K. S., and McConlogue, L. (1994) Cell Motil. Cytoskeleton 28, 195-198.
47. Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B., Mandelkow, E.-M., and Mandelkow, E. (1998) J. Cell Biol. 143, 777-794.
48. Ksiezak-Reding, H., Liu, W. K., and Yen, S. H. (1992) Brain Res. 597, 209-219.
49. Matsuo, E. S., Shin, R. W., Billingsley, M. L., Vandevoorde, A., Oconnor, M., Trojanowski, J. Q., and Lee, V. M. Y. (1994) Neuron 13, 989-1002.
50. Cleveland, D. W., Hwo, S.-Y., and Kirschner, M. W. (1977) J. Mol. Biol. 116, 227-247.
51. Lee, G., Cowan, N., and Kirschner, M. (1988) Science 239, 285-288.
52. Novak, M., Kabat, J., and Wischik, C. M. (1993) EMBO J. 12, 365-370.
53. Drewes, G., Ebneth, A., and Mandelkow, E.-M. (1998) Trends Biochem. Sci. 23, 307-311.
54. Schweers, O., Schönbrunn, E., Marx, A., and Mandelkow, E. (1994) J. Biol. Chem. 269, 24290-24297.
55. Scott, C., Spreen, R., Herman, J., Chow, F., Davison, M., Young, J., and Caputo, C. (1993) J. Biol. Chem. 268, 1166-1173.
56. Lichtenberg-Kraag, B., Mandelkow, E.-M., Biernat, J., Steiner, B., Schröter, C., Gustke, N., Meyer, H.E., and Mandelkow, E. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 5384-5388.
57. Carmel, G., Mager, E. M., Binder, L. I., and Kuret, J. (1996) J. Biol. Chem. 271, 32789-32795.
58. Jicha, G. A., Bowser, R., Kazam, I. G., and Davies, P. (1997) J. Neurosci. Res. 48, 128-132.
59. Goode, B., Denis, P., Panda, D., Radeke, M., Miller, H., Wilson, L., and Feinstein, S. (1997) Mol. Biol. Cell 8, 353-365.
60. Greenberg, S. G., Davies, P., Schein, J. D., and Binder, L. I. (1992) J. Biol. Chem. 267, 564-569.
61. Papasozomenos, S., and Su, Y. (1995) J. Neurochem. 65, 396-406.
62. Song, J., Combs, C., Pilcher, W., Song, L., Utal, A., and Coleman, P. (1997) Neurobiol. Aging 18, 475-481.
63. Litersky, J. M., and Johnson, G. V. W. (1992) J. Biol. Chem. 267, 1563-1568.
64. Mercken, M., Grynspan, F., and Nixon, R. A. (1995) FEBS Lett. 368, 10-14.
65. Drechsel, D. N., Hyman, A. A., Cobb, M. H., and Kirschner, M. W. (1992) Mol. Biol. Cell 3, 1141-1154.
66. Hasegawa, M., Morishima-Kawashima, M., Takio, K., Suzuki, M., Titani, K., and Ihara, Y. (1992) J. Biol. Chem. 267, 17047-17054.
67. Litersky, J., Johnson, G., Jakes, R., Goedert, M., Lee, M., and Seubert, P. (1996) Biochem. J. 316, 655-660.