Conversion of serine to aspartate imitates phosphorylation-induced changes in the structure and function of microtubule-associated protein tau

Journal of Biological Chemistry

Volumn 272, Issue 13, 1997, Pages 8441-8446

  Léger, Jocelyne ^a   Kempf, Martina ^b   Lee, Gloria ^a   Brandt, Roland ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; SERINE; TAU PROTEIN;

ALTERNATIVE RNA SPLICING; ALZHEIMER DISEASE; ARTICLE; CONFORMATIONAL TRANSITION; DEPHOSPHORYLATION; DNA FLANKING REGION; ELECTROPHORETIC MOBILITY; NEUROFIBRILLARY TANGLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE;

ANIMALS; ASPARTIC ACID; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOCHALASINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEPARIN; HUMANS; MICROTUBULES; MUTAGENESIS, SITE-DIRECTED; PC12 CELLS; PHOSPHORYLATION; RATS; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP; TAU PROTEINS;

EID: 0038982381     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.13.8441     Document Type: Article

References (42)

1. Goedert, M., Crowther, R. A., and Garner, C. C. (1991) Trends Neurosci. 14, 193-199
2. Brandt, R. (1996) Frontiers Biosci. 1, 118-130
3. Lee, G. (1993) Curr Opin. Cell Biol. 5, 88-94
4. Lindwall, G., and Cole, R.D. (1984) J. Biol. Chem. 259, 5301-5305
5. Biernat, J., Gustke, N., Drewes, G., Mandelkow, E.-M., and Mandelkow, E. (1993) Neuron 11, 153-163
6. Drewes, G., Trinczek, B., Illenberger, S., Biernat, J., Schmitt-Ulms, G., Meyer, H. E., Mandelkow, E.-M., and Mandelkow, E. (1995) J. Biol. Chem. 270, 7679-7688
7. Drechsel, D. N., Hyman, A. A., Cobb, M. H., and Kirschner, M. W. (1992) Mol. Biol. Cell 3, 1141-1154
8. Trinczek, B., Biernat, J., Baumann, K., Mandelkow, E. M., and Mandelkow, E. (1995) Mol. Biol. Cell 6, 1887-1902
9. Hagestedt, T., Lichtenberg, B., Wille, H., Mandelkow, E. M., and Mandelkow, E. (1989) J. Cell Biol. 109, 1643-1651
10. Steiner, B., Mandelkow, E. M., Biernat, J., Gustke, N., Meyer, H. E., Schmidt, B., Mieskes, G., Soling, H. D., Drechsel, D., Kirschner, M. W., Goedert, M., and Mandelkow, E. (1990) EMBO J. 9, 3539-3544
11. Scott, C. W., Spreen, R. C., Herman, J. L., Chow, F. P., Davison, M. D., Young, J., and Caputo, C. B. (1993) J. Biol. Chem. 268, 1165-1173
12. Brandt, R., and Lee, G. (1994) Cell Motil. Cytoskeleton 28, 143-154
13. Brandt, R., Lee, G., Teplow, D. B., Shalloway, D., and Abdel-Ghany, M. (1994) J. Biol. Chem. 269, 11776-11782
14. Walaas, S. I., and Greengard, P. (1991) Pharmacol. Rev. 43, 299-349
15. Mandelkow, E. M., and Mandelkow, E. (1993) Trends Biochem. Sci. 18, 480-483
16. Kosik, K. S. (1994) J. Cell Biol. 127, 1501-1504
17. Lee, V. M., Balin, B. J., Otvos, L. J., and Trojanoweki, J. Q. (1991) Science 251, 675-678
18. Brion, J. P., Hanger, D. P., Bruce, M. T., Couck, A. M., Flament, D. J., and Anderton, B. H. (1991) Biochem. J. 273, 127-133
19. Greenberg, S. G., Davies, P., Schein, J. D., and Binder, L. I. (1992) J. Biol. Chem. 267, 564-569
20. Lu, Q., and Wood, J. G. (1993) J. Neurosci. 13, 508-515
21. Morishima-Kawashima, M., Hasegawa, M., Takio, K., Suzuki, M., Yoshida, H., Titani, K., and Ihara, Y. (1995) J. Biol. Chem. 270, 823-829
22. Goedert, M., Wischik, C. M., Crowther, R. A., Walker, J. E. and Klug, A. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 4051-4055
23. Egelhoff, T. T., Lee, R. J., and Spudich, J. A. (1993) Cell 75, 363-371
24. Huang, W., and Erikson, R. L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8960-8963
25. Brandt, R., and Lee, G. (1993) J. Biol. Chem. 268, 3414-3419
26. Kunkel, T. A., Roberts, J. D., and Zakour, R. A. (1987) Methods Enzymol. 154, 367-382
27. Hopp, T. P., Prickett, K. S., Price, V. L., Libby, R. T., March, C. J., Carretti, D. P., Urdal, D. L., and Conlon, P. J. (1968) Bio/Technology 6, 1204-1210
28. Prickett, K. S., Amberg, D. C. and Hopp, T. (1989) BioTechniques 7, 580-589
29. Studier, F. W., Rosenberg, A. H., Dunn, J. J., and Dubendorff, J. W. (1990) Methods Enzymol. 185, 60-89
30. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
31. Léger, J. Brandt, R., and Lee, G. (1994) J. Cell Sci. 107, 3403-3412
32. Laemmli, U. K., and Favre, M. (1973) J. Mol. Biol. 80, 575-599
33. Baudier, J., and Cole, R. D. (1987) J. Biol. Chem. 262, 17577-17583
34. Litersky, J. M., and Johnson, G. V. W. (1992) J. Biol. Chem. 267, 1563-1568
35. Brandt, R., and Lee, G. (1993) J. Neurochem. 61, 997-1005
36. Edson, K., Weisshaar, B., and Matuz, A. (1993) Development 117, 689-700
37. Drubin, D. G., and Kirschner, M. W. (1986) J. Cell Biol. 103, 2739-2746
38. Lee, G., and Rook, S. L. (1992) J. Cell Sci. 102, 227-237
39. Kosik, K. S., Orecchio, L. D., Binder, L., Trojanowski, J. Q., Lee, V. M., and Lee, G. (1988) Neuron 1, 817-825
40. Liu, W. K., Moore, W. T., Williams, R. T., Hall, F. L., and Yen, S. H. (1993) J. Neurosci. Res. 34, 371-376
41. Szendrei, G. L., Lee, V. M., and Otvos, L. J. (1993) J. Neurosci. Res. 34, 243-249
42. Walker, R. A., O'Brien, E. T., Pryer, N. K., Soboeiro, M. F., Voter, W. A., Erickson, H. P., and Salmon, E. D. (1986) J. Cell Biol. 107, 1437-1448