Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and Tau proteins

Molecular Cell

Volumn 6, Issue 4, 2000, Pages 873-883

  Zhou, Xiao Zhen ^a   Kops, Oliver ^a   Werner, Andreas ^b   Lu, Pei Jung ^a   Shen, Minhui ^a   Stoller, Gerlind ^a   Küllertz, Gerhard ^b   Stark, Michael ^c   Fischer, Gunter ^b   Lu, Kun Ping ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ISOMERASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE; TAU PROTEIN;

ARTICLE; CATALYSIS; CELL DIVISION; DEPHOSPHORYLATION; ENZYME ACTIVITY; ISOMERISM; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; YEAST;

EID: 0033638180     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(05)00083-3     Document Type: Article

References (45)

1. A hyperphosphorylated form of RNA polymerase II is the major interphase antigen of the phosphoprotein antibody MPM-2 and interacts with the peptidylprolyl isomerase Pin1
2. A phosphatase activity in Xenopus oocyte extracts preferentially dephosphorylates the MPM-2 epitope
3. Dephosphorylation of cdc25-C by a type-2A protein phosphatase: Specific regulation during the cell cycle in Xenopus egg extracts
4. The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1
5. All cyclophilins and FKBPs are dispensible for viability in Saccharomyces cerevisiae
6. Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcineurin and phosphatase-2A
7. Mutations in the Saccharomyces cerevisiae type 2A protein phosphatase catalytic subunit reveal roles in cell wall integrity, actin cytoskeleton organization and mitosis
8. Peptidyl-prolyl cis/trans isomerases
9. Sequence and mutational analysis of ESS1, a gene essential for growth in Saccharomyces cerevisiae
10. PTF1 encodes an essential protein in Saccharomyces cerevisiae, which shows strong homology with a new putative family of PPlases
11. Mutations in a peptidylprolyl-cis/trans-isomerase gene lead to a defect in 3'-end formation of a pre-mRNA in Saccharomyces cerevisiae
12. Prolyl isomerase and nuclear function
13. Elimination of cdc2 phosphorylation sites in the Cdc25 phosphatase blocks initiation of M-phase
14. Phosphatase 2A and polo kinase, two antagonistic regulators of Cdc25 activation and MPF auto-amplification
15. HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint
16. Cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor
17. Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts
18. INH, a negative regulator of MPF, is a form of protein phosphatase 2A
19. Isolation and characterization of new alleles of the cyclin-dependent kinase gene CDC28 with cyclin-specific functional and biochemical defects
20. The role of Saccharomyces cerevisiae type 2A phosphatase in the actin cytoskeleton and in entry into mitosis
21. A human peptidyl-prolyl isomerase essential for regulation of mitosis
22. Prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
23. A function of WW domains as phosphoserine- or phosphothreonine-binding modules
24. Identification of novel M phase phosphoproteins by expression cloning
25. Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast
26. Phosphocarboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-end formation
27. Cyclin-dependent protein kinases: Key regulators of the eukaryote cell cycle
28. The Xenopus Suc1/Cks protein promotes the phosphorylation of G(2)/M regulators
29. Mitotic phosphorylation of tau protein in neuronal cell lines resembles phosphorylation in Alzheimer's disease
30. Structural and functional analysis of the mitotic peptidyl-prolyl isomerase Pin1 suggests that substrate recognition is phosphorylation dependent
31. Intramolecular assistance of cis/trans isomerization of the histidine-proline moiety
32. Protein phosphatase 2A in Saccharomyces cerevisiae: Effects on cell growth and bud morphogenesis
33. Role of phosphorylation in determining the backbone dynamics of the serine/threonine-proline motif and Pin1 substrate recognition
34. The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins
35. Protein (serine and threonine) phosphate phosphatases
36. p34cdc2 phosphorylation sites in histone H1 are dephosphorylated by protein phosphatase 2A1
37. Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A
38. Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies
39. Systematic identification of mitotic phosphoproteins
40. Mitotic mechanisms in Alzheimer's disease?
41. Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease
42. Requirement of the prolyl isomerase Pin1 for the replication checkpoint
43. The structural basis for 14-3-3: Phosphopeptide binding specificity
44. Sequence-specific and phosphorylation-dependent proline isomerization: A potential mitotic regulatory mechanism
45. Phosphorylation-dependent prolyl isomerization: A novel signaling regulatory mechanism