Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein

Biochemical Journal

Volumn 357, Issue 3, 2001, Pages 759-767

  Eidenmuller J ^a   Fath, T ^a   Maas, T ^a   Pool, M ^a   Sontag, E ^a   Brandt, R ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Alzheimer's disease; Microtubule; Paired helical filaments; Protein phosphatase 2A

Indexed keywords

AGGLOMERATION; PATHOLOGY; PHOSPHATES; PROTEINS;

PHOSPHOPROTEINS;

GLUCOSE;

GLUTAMIC ACID; PROLINE; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE;

BINDING SITES; CELL MEMBRANE; GLUTAMIC ACID; HUMANS; MICROTUBULE-ORGANIZING CENTER; MICROTUBULES; NEURONS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROLINE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TAU PROTEINS;

EID: 0035425347     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3570759     Document Type: Article

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