Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome

FASEB Journal

Volumn 22, Issue 9, 2008, Pages 3224-3233

  Liu, Fei ^a   Liang, Zhihou ^a   Wegiel, Jerzy ^a   Hwang, Yu Wen ^a   Iqbal, Khalid ^a   Grundke Iqbal, Inge ^a   Ramakrishna, Narayan ^a   Gong, Cheng Xin ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

GSK 3 ; Hyperphosphorylation; Tau; Trisomy 21

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; TAU PROTEIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOWN SYNDROME; DUAL SPECIFICITY TYROSINE PHOSPHORYLATED AND REGULATED KINASE 1A; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME KINETICS; FEMALE; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; MALE; NEUROFIBRILLARY DEGENERATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; TRISOMY;

AGED; AGED, 80 AND OVER; ANIMALS; DOWN SYNDROME; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MALE; MICE; MIDDLE AGED; NERVE DEGENERATION; NEUROFIBRILLARY TANGLES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; TAU PROTEINS;

EID: 51349109221     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-104539     Document Type: Article

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