The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity

Journal of Neuroscience Research

Volumn 87, Issue 2, 2009, Pages 440-451

  LaPointe, Nichole E ^a,b   Morfini, Gerardo ^b,c   Pigino, Gustavo ^b,c   Gaisina, Irina N ^c   Kozikowski, Alan P ^c   Binder, Lester I ^a   Brady, Scott T ^b,c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b MARINE BIOLOGICAL LABORATORY   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Alzheimer's disease; Axonal transport; GSK3; Kinesin; PP1; Tau; Tau filament

Indexed keywords

AMINO ACID; DYNEIN ADENOSINE TRIPHOSPHATASE; GLYCOGEN SYNTHASE KINASE 3; KINESIN; PHOSPHOPROTEIN PHOSPHATASE 1; RECOMBINANT PROTEIN; TAU PROTEIN; ISOPROTEIN;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; AXOPLASM; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEGENERATIVE DISEASE; MICROSCOPY; MICROTUBULE; NERVE FIBER TRANSPORT; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; SQUID; ANIMAL; CEPHALOPOD; CHEMISTRY; CYTOSKELETON; HUMAN; IMMUNOBLOTTING; METABOLISM; PHYSIOLOGY;

ANIMALS; AXONAL TRANSPORT; CYTOSKELETON; DECAPODIFORMES; GLYCOGEN SYNTHASE KINASE 3; HUMANS; IMMUNOBLOTTING; KINESIN; MICROTUBULES; PROTEIN ISOFORMS; PROTEIN PHOSPHATASE 1; TAU PROTEINS;

EID: 62849088641     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21850     Document Type: Article

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