-
1
-
-
0032476645
-
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease
-
Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B. and Mandelkow, E. (1998) Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease. J. Cell Biol., 143, 777-794.
-
(1998)
J. Cell Biol.
, vol.143
, pp. 777-794
-
-
Ebneth, A.1
Godemann, R.2
Stamer, K.3
Illenberger, S.4
Trinczek, B.5
Mandelkow, E.6
-
2
-
-
0028118917
-
Microtubule organization and dynamics dependent on microtubule-associated proteins
-
Hirokawa, N. (1994) Microtubule organization and dynamics dependent on microtubule-associated proteins. Curr. Opin. Cell. Biol., 6, 74-81.
-
(1994)
Curr. Opin. Cell. Biol.
, vol.6
, pp. 74-81
-
-
Hirokawa, N.1
-
3
-
-
0026488111
-
Structure and novel exons of the human tau gene
-
Andreadis, A., Brown, W.M. and Kosik, K.S. (1992) Structure and novel exons of the human tau gene. Biochemistry, 31, 10626-10633.
-
(1992)
Biochemistry
, vol.31
, pp. 10626-10633
-
-
Andreadis, A.1
Brown, W.M.2
Kosik, K.S.3
-
4
-
-
0022827447
-
Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2
-
Neve, R.L., Harris, P., Kosik, K.S., Kurnit, D.M. and Donlon, T.A. (1986) Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2. Brain Res., 387, 271-280.
-
(1986)
Brain Res.
, vol.387
, pp. 271-280
-
-
Neve, R.L.1
Harris, P.2
Kosik, K.S.3
Kurnit, D.M.4
Donlon, T.A.5
-
5
-
-
0002792366
-
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau
-
Goedert, M., Wischik, C.M., Crowther, R.A., Walker, J.E. and Klug, A. (1988) Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau. Proc. Natl Acad. Sci. USA, 85, 4051-4055.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 4051-4055
-
-
Goedert, M.1
Wischik, C.M.2
Crowther, R.A.3
Walker, J.E.4
Klug, A.5
-
6
-
-
0024387161
-
Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: Differential expression of tau protein mRNAs in human brain
-
Goedert, M., Spillantini, M.G., Potier, M.C., Ulrich, J. and Crowther, R.A. (1989) Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: Differential expression of tau protein mRNAs in human brain. EMBO J., 8, 393-399.
-
(1989)
EMBO J.
, vol.8
, pp. 393-399
-
-
Goedert, M.1
Spillantini, M.G.2
Potier, M.C.3
Ulrich, J.4
Crowther, R.A.5
-
7
-
-
0024745894
-
Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease
-
Goedert, M., Spillantini, M.G., Jakes, R., Rutherford, D. and Crowther, R.A. (1989) Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron, 3, 519-526.
-
(1989)
Neuron
, vol.3
, pp. 519-526
-
-
Goedert, M.1
Spillantini, M.G.2
Jakes, R.3
Rutherford, D.4
Crowther, R.A.5
-
8
-
-
0026711059
-
Fetal-type phosphorylation of the tau in paired helical filaments
-
Kanemaru, K., Takio, K., Miura, R., Titani, K. and Ihara, Y. (1992) Fetal-type phosphorylation of the tau in paired helical filaments. J. Neurochem., 58, 1667-1675.
-
(1992)
J. Neurochem.
, vol.58
, pp. 1667-1675
-
-
Kanemaru, K.1
Takio, K.2
Miura, R.3
Titani, K.4
Ihara, Y.5
-
9
-
-
14444284106
-
Tau is a candidate gene for chromosome 17 frontotemporal dementia
-
Poorkaj, P., Bird, T.D., Wijsman, E., Nemens, E., Garruto, R.M., Anderson, L., Andreadis, A., Wiederholt, W.C., Raskind, M. and Schellenberg, G.D. (1998) Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann. Neurol., 43, 815-825.
-
(1998)
Ann. Neurol.
, vol.43
, pp. 815-825
-
-
Poorkaj, P.1
Bird, T.D.2
Wijsman, E.3
Nemens, E.4
Garruto, R.M.5
Anderson, L.6
Andreadis, A.7
Wiederholt, W.C.8
Raskind, M.9
Schellenberg, G.D.10
-
10
-
-
0032560487
-
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
-
Spillantini, M.G., Murrell, J.R., Goedert, M., Farlow, M.R., Klug, A. and Ghetti, B. (1998) Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc. Natl Acad. Sci. USA, 95, 7737-7741.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7737-7741
-
-
Spillantini, M.G.1
Murrell, J.R.2
Goedert, M.3
Farlow, M.R.4
Klug, A.5
Ghetti, B.6
-
11
-
-
0032543684
-
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton, M., L.endon, C.L., Rizzu, P., Baker, M., Froelich, S., Houlden, H., Pickering-Brown, S., Chakraverty, S., Isaacs, A., Grover, A. et al. (1998) Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature, 393, 702-705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
-
12
-
-
0033013126
-
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions
-
Ballinger, C.A., Connell, P., Wu, Y., Hu, Z., Thompson, L.J., Yin, L.Y. and Patterson, C. (1999) Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions. Mol. Cell. Biol., 19, 4535-4545.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4535-4545
-
-
Ballinger, C.A.1
Connell, P.2
Wu, Y.3
Hu, Z.4
Thompson, L.J.5
Yin, L.Y.6
Patterson, C.7
-
13
-
-
0035900793
-
CHIP is a U-box-dependent E3 ubiquitin ligase: Identification of Hsc70 as a target for ubiquitylation
-
Jiang, J., Ballinger, C.A., Wu, Y., Dai, Q., Cyr, D.M., Hohfeld, J. and Patterson, C. (2001) CHIP is a U-box-dependent E3 ubiquitin ligase: Identification of Hsc70 as a target for ubiquitylation. J. Biol. Chem., 276, 42939-42944.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42939-42944
-
-
Jiang, J.1
Ballinger, C.A.2
Wu, Y.3
Dai, Q.4
Cyr, D.M.5
Hohfeld, J.6
Patterson, C.7
-
14
-
-
0037331016
-
C-terminal Hsp-interacting protein slows androgen receptor synthesis and reduces its rate of degradation
-
Cardozo, C.P., Michaud, C., Ost, M.C., Fliss, A.E., Yang, E., Patterson, C., Hall, S.J. and Caplan, A.J. (2003) C-terminal Hsp-interacting protein slows androgen receptor synthesis and reduces its rate of degradation. Arch. Biochem. Biophys., 410, 134-140.
-
(2003)
Arch. Biochem. Biophys.
, vol.410
, pp. 134-140
-
-
Cardozo, C.P.1
Michaud, C.2
Ost, M.C.3
Fliss, A.E.4
Yang, E.5
Patterson, C.6
Hall, S.J.7
Caplan, A.J.8
-
15
-
-
0035146685
-
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
-
Connell, P., Ballinger, C.A., Jiang, J., Wu, Y., Thompson, L.J., Hohfeld, J. and Patterson, C. (2001) The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins. Nat. Cell. Biol., 3, 93-96.
-
(2001)
Nat. Cell. Biol.
, vol.3
, pp. 93-96
-
-
Connell, P.1
Ballinger, C.A.2
Jiang, J.3
Wu, Y.4
Thompson, L.J.5
Hohfeld, J.6
Patterson, C.7
-
16
-
-
0035142877
-
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
-
Meacham, G.C., Patterson, C., Zhang, W., Younger, J.M. and Cyr, D.M. (2001) The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation. Nat. Cell. Biol., 3, 100-105.
-
(2001)
Nat. Cell. Biol.
, vol.3
, pp. 100-105
-
-
Meacham, G.C.1
Patterson, C.2
Zhang, W.3
Younger, J.M.4
Cyr, D.M.5
-
17
-
-
0035147404
-
Molecular chaperones and the art of recognizing a lost cause
-
McClellan, A.J. and Frydman, J. (2001) Molecular chaperones and the art of recognizing a lost cause. Nat. Cell. Biol., 3, E51-53.
-
(2001)
Nat. Cell. Biol.
, vol.3
-
-
McClellan, A.J.1
Frydman, J.2
-
18
-
-
0036345454
-
CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity
-
Imai, Y., Soda, M., Hatakeyama, S., Akagi, T., Hashikawa, T., Nakayama, K.I. and Takahashi, R. (2002) CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol. Cell., 10, 55-67.
-
(2002)
Mol. Cell.
, vol.10
, pp. 55-67
-
-
Imai, Y.1
Soda, M.2
Hatakeyama, S.3
Akagi, T.4
Hashikawa, T.5
Nakayama, K.I.6
Takahashi, R.7
-
19
-
-
0034680913
-
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
-
Imai, Y., Soda, M. and Takahashi, R. (2000) Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J. Biol. Chem., 275, 35661-35664.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35661-35664
-
-
Imai, Y.1
Soda, M.2
Takahashi, R.3
-
20
-
-
0037457966
-
Chaperones increase association of tau protein with microtubules
-
Dou, F., Netzer, W.J., Tanemura, K., Li, F., Hartl, F.U., Takashima, A., Gouras, G.K., Greengard, P. and Xu, H. (2003) Chaperones increase association of tau protein with microtubules. Proc. Natl Acad. Sci. USA, 100, 721-726.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 721-726
-
-
Dou, F.1
Netzer, W.J.2
Tanemura, K.3
Li, F.4
Hartl, F.U.5
Takashima, A.6
Gouras, G.K.7
Greengard, P.8
Xu, H.9
-
21
-
-
0031838352
-
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
-
Cummings, C.J., Mancini, M.A., Antalffy, B., DeFranco, D.B., Orr, H.T. and Zoghbi, H.Y. (1998) Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nat. Genet., 19, 148-154.
-
(1998)
Nat. Genet.
, vol.19
, pp. 148-154
-
-
Cummings, C.J.1
Mancini, M.A.2
Antalffy, B.3
DeFranco, D.B.4
Orr, H.T.5
Zoghbi, H.Y.6
-
22
-
-
0036852712
-
Pharmacological prevention of Parkinson disease in Drosophila
-
Auluck, P.K. and Bonini, N.M. (2002) Pharmacological prevention of Parkinson disease in Drosophila. Nat. Med., 8, 1185-1186.
-
(2002)
Nat. Med.
, vol.8
, pp. 1185-1186
-
-
Auluck, P.K.1
Bonini, N.M.2
-
23
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck, P.K., Chan, H.Y., Trojanowski, J.Q., Lee, V.M. and Bonini, N.M. (2002) Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science, 295, 865-868.
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
24
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
-
Yang, Y., Nishimura, I., Imai, Y., Takahashi, R. and Lu, B. (2003) Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron, 37, 911-924.
-
(2003)
Neuron
, vol.37
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
25
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., Yokochi, M., Mizuno, Y. and Shimizu, N. (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature, 392, 605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
26
-
-
0034426011
-
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L.) tau protein
-
Lewis, J., McGowan, E., Rockwood, J., Melrose, H., Nacharaju, P., Van Slegtenhorst, M., Gwinn-Hardy, K., Paul Murphy, M., Baker, M., Yu, X. et al. (2000) Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L.) tau protein. Nat. Genet., 25, 402-405.
-
(2000)
Nat. Genet.
, vol.25
, pp. 402-405
-
-
Lewis, J.1
McGowan, E.2
Rockwood, J.3
Melrose, H.4
Nacharaju, P.5
Van Slegtenhorst, M.6
Gwinn-Hardy, K.7
Paul Murphy, M.8
Baker, M.9
Yu, X.10
-
27
-
-
0037072667
-
Cell biology. Ubiquitin lives up to its name
-
Marx, J. (2002) Cell biology. Ubiquitin lives up to its name. Science, 297, 1792-1794.
-
(2002)
Science
, vol.297
, pp. 1792-1794
-
-
Marx, J.1
-
28
-
-
0032898588
-
Modulation of tolerance by mutant heat shock transcription factors
-
Xia, W., Vilaboa, N., Martin, J.L., Mestril, R., Guo, Y. and Voellmy, R. (1999) Modulation of tolerance by mutant heat shock transcription factors. Cell Stress Chaperones, 4, 8-18.
-
(1999)
Cell Stress Chaperones
, vol.4
, pp. 8-18
-
-
Xia, W.1
Vilaboa, N.2
Martin, J.L.3
Mestril, R.4
Guo, Y.5
Voellmy, R.6
-
29
-
-
0028064940
-
Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: Essential role for stress proteins in oncogenic transformation
-
Whitesell, L., Mimnaugh, E.G., De Costa, B., Myers, C.E. and Neckers, L.M. (1994) Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: Essential role for stress proteins in oncogenic transformation. Proc. Natl Acad. Sci. USA, 91, 8324-8328.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8324-8328
-
-
Whitesell, L.1
Mimnaugh, E.G.2
De Costa, B.3
Myers, C.E.4
Neckers, L.M.5
-
30
-
-
0032555685
-
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1
-
Zou, J., Guo, Y., Guettouche, T., Smith, D.F. and Voellmy, R. (1998) Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1. Cell, 94, 471-480.
-
(1998)
Cell
, vol.94
, pp. 471-480
-
-
Zou, J.1
Guo, Y.2
Guettouche, T.3
Smith, D.F.4
Voellmy, R.5
-
31
-
-
0028932259
-
Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury
-
Marber, M.S., Mestril, R., Chi, S.H., Sayen, M.R., Yellon, D.M. and Dillmann, W.H. (1995) Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J. Clin. Invest., 95, 1446-1456.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 1446-1456
-
-
Marber, M.S.1
Mestril, R.2
Chi, S.H.3
Sayen, M.R.4
Yellon, D.M.5
Dillmann, W.H.6
-
32
-
-
0023917701
-
Alz-50, ubiquitin and tau immunoreactivity of neurofibrillary tangles, Pick bodies and Lewy bodies
-
Love, S., Saitoh, T., Quijada, S., Cole, G.M. and Terry, R.D. (1988) Alz-50, ubiquitin and tau immunoreactivity of neurofibrillary tangles, Pick bodies and Lewy bodies. J. Neuropathol. Exp. Neurol., 47, 393-405.
-
(1988)
J. Neuropathol. Exp. Neurol.
, vol.47
, pp. 393-405
-
-
Love, S.1
Saitoh, T.2
Quijada, S.3
Cole, G.M.4
Terry, R.D.5
-
33
-
-
10744223839
-
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
-
Dai, Q., Zhang, C., Wu, Y., McDonough, H., Whaley, R.A., Godfrey, V., Li, H.H., Madamanchi, N., Xu, W., Neckers, L. et al. (2003) CHIP activates HSF1 and confers protection against apoptosis and cellular stress. EMBO J., 22, 5446-5458.
-
(2003)
EMBO J.
, vol.22
, pp. 5446-5458
-
-
Dai, Q.1
Zhang, C.2
Wu, Y.3
McDonough, H.4
Whaley, R.A.5
Godfrey, V.6
Li, H.H.7
Madamanchi, N.8
Xu, W.9
Neckers, L.10
-
34
-
-
1042266624
-
CHIP-Hsc70 complex ubiquitinates phosphorylated Tau and enhances cell survival
-
in press
-
Shimura, H., Schwartz, D., Gygi, S.R and Kosik, K.S. (2004) CHIP-Hsc70 complex ubiquitinates phosphorylated Tau and enhances cell survival. J. Biol. Chem., in press.
-
(2004)
J. Biol. Chem.
-
-
Shimura, H.1
Schwartz, D.2
Gygi, S.R.3
Kosik, K.S.4
-
35
-
-
0028246505
-
Corticobasal degeneration: Etiopathological significance of the cytoskeletal alterations
-
Wakabayashi, K., Oyanagi, K., Makifuchi, T., Ikuta, F., Homma, A., Homma, Y., Horikawa, Y. and Tokiguchi, S. (1994) Corticobasal degeneration: Etiopathological significance of the cytoskeletal alterations. Acta. Neuropathol. (Berl.), 87, 545-553.
-
(1994)
Acta Neuropathol. (Berl.)
, vol.87
, pp. 545-553
-
-
Wakabayashi, K.1
Oyanagi, K.2
Makifuchi, T.3
Ikuta, F.4
Homma, A.5
Homma, Y.6
Horikawa, Y.7
Tokiguchi, S.8
-
36
-
-
0026543843
-
Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue
-
Yamada, T., McGeer, P.L. and McGeer, E.G. (1992) Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue. Neurosci. Lett., 135, 99-102.
-
(1992)
Neurosci. Lett.
, vol.135
, pp. 99-102
-
-
Yamada, T.1
McGeer, P.L.2
McGeer, E.G.3
-
37
-
-
0028183609
-
Cortical tangles in progressive supranuclear palsy
-
Verny, M., Duyckaerts, C., Delaere, P., He, Y. and Hauw, J.J. (1994) Cortical tangles in progressive supranuclear palsy. J. Neural. Transm. Suppl., 42, 179-188.
-
(1994)
J. Neural. Transm. Suppl.
, vol.42
, pp. 179-188
-
-
Verny, M.1
Duyckaerts, C.2
Delaere, P.3
He, Y.4
Hauw, J.J.5
-
38
-
-
0031690269
-
Ubiquitin immunoreactivity of paired helical filaments differs in Alzheimer's disease and corticobasal degeneration
-
Yang, L. and Ksiezak-Reding, H. (1998) Ubiquitin immunoreactivity of paired helical filaments differs in Alzheimer's disease and corticobasal degeneration. Acta. Neurupathol. (Berl.), 96, 520-526.
-
(1998)
Acta Neurupathol. (Berl.)
, vol.96
, pp. 520-526
-
-
Yang, L.1
Ksiezak-Reding, H.2
|