Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 10, 2000, Pages 5129-5134

  Von Bergen, M ^a   Friedhoff, P ^b   Biernat, J ^a   Heberle, J ^c   Mandelkow, E M ^a   Mandelkow, E ^a  

^a MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BRAIN PROTEIN; HEPARIN; HEXAPEPTIDE; PROLINE;

ALZHEIMER DISEASE; ARTICLE; DEMENTIA; ESCHERICHIA COLI; FOURIER TRANSFORMATION; HUMAN; INFRARED SPECTROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; CIRCULAR DICHROISM; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TAU PROTEINS;

ESCHERICHIA COLI;

EID: 0034625060     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.10.5129     Document Type: Article

References (39)

1. Koo, E. H., Lansbury, P. T., Jr. & Kelly, J. W. (1999) Proc. Natl. Acad. Sci. USA 96, 9989-9990.
2. Friedhoff, P. & Mandelkow, E. (1998) in Guidebook to the Cytoskeletal and Motor Proteins, eds. Kreis, T. & Vale, R. (Oxford Univ. Press, Oxford), pp. 230-236.
3. Goedert, M., Spillantini, G., Cairns, N. J. & Crowther, R. A. (1992) Neuron 8, 159-168.
4. Wischik, C., Novak, M., Thogersen, H., Edwards, P., Runswick, M., Jakes, R., Walker, J., Milstein, C., Roth, M. & Klug, A. (1988) Proc. Natl. Acad. Sci. USA 85, 4506-4510.
5. Wille, H., Drewes, G., Biernat, J., Mandelkow, E. M. & Mandelkow, E. (1992) J. Cell Biol. 118, 573-584.
6. Cleveland, D. W., Hwo, S. Y. & Kirschner, M. W. (1977) J. Mol. Biol. 116, 227-247.
7. Schweers, O., Schönbrunn-Hanebeck, E., Marx, A. & Mandelkow, E. (1994) J. Biol. Chem. 269, 24290-24297.
8. Perez, M., Valpuesta, J. M., Medina, M., Degarcini, E. M. & Avila, J. (1996) J. Neurochem. 67, 1183-1190.
9. Goedert, M., Jakes, R., Spillantini, M. G., Hasegawa, M., Smith, M. J. & Crowther, R. A. (1996) Nature (London) 383, 550-553.
10. Friedhoff, P., Schneider, A., Mandelkow, E. M. & Mandelkow, E. (1998) Biochemistry 37, 10223-10230.
11. Kampers, T., Friedhoff, P., Biernat, J. & Mandelkow, E. M. (1996) FEBS Lett. 399, 344-349.
12. Friedhoff, P., von Bergen, M., Mandelkow, E. M., Davies, P. & Mandelkow, E. (1998) Proc. Natl. Acad. Sci. USA 95, 15712-15717.
13. King, M. E., Ahuja, V., Binder, L. I. & Kuret, J. (1999) Biochemistry 38, 14851-14859.
14. Crowther, R. A. (1991) Proc. Natl. Acad. Sci. USA 88, 2288-2292.
15. Wilson, D. M. & Binder, L. I. (1997) Am. J. Pathol. 150, 2181-2195.
16. Wille, H., Mandelkow, E. M. & Mandelkow, E. (1992) J. Biol. Chem. 267, 10737-10742.
17. DeTure, M. A., Zhang, E. Y., Bubb, M. R. & Purich, D. L. (1996) J. Biol. Chem. 271, 32702-32706.
18. Biernat, J., Mandelkow, E. M., Schröter, C., Lichtenberg-Kraag, B., Steiner, B., Berling, B., Meyer, H. E., Mercken, M., Vandermeeren, A., Goedert, M., et al. (1992) EMBO J. 11, 1593-1597.
19. Goedert, M., Wischik, C., Crowther, R., Walker, J. & Klug, A. (1988) Proc. Natl. Acad. Sci. USA 85, 4051-4055.
20. Gustke, N., Trinczek, B., Biernat, J., Mandelkow, E. M. & Mandelkow, E. (1994) Biochemistry 33, 9511-9522.
21. Udenfriend, S., Stein, S., Bohlen, P., Dairman, W., Leimgruber, W. & Weigele, M. (1972) Science 178, 871-872.
22. Frank, R. (1995) J. Biotechnol. 41, 259-272.
23. Zscherp, C. & Heberle, J. (1997) J. Phys. Chem. B 101, 10542-10547.
24. Heberte, J. (1999) Rec. Res. Dev. Appl. Spectrosc. 2, 147-159.
25. Schweers, O., Mandelkow, E. M., Biernat, J. & Mandelkow, E. (1995) Proc. Natl. Acad. Sci. USA 92, 8463-8467.
26. Hoffmann, R., Dawson, N. F., Wade, J. D. & Otvos, L., Jr. (1997) J. Pep. Res. 50, 132-142.
27. Fabian, H., Szendrei, G. I., Mantsch, H. H. & Otvos, L., Jr. (1993) Biochem. Biophys. Res. Commun. 191, 232-239.
28. Schladitz, C., Vieira, E. P., Hermel, H. & Mohwald, H. (1999) Biophys. J. 77, 3305-3310.
29. Wood, S. J., Wetzel, R., Martin, J. D. & Hurle, M. R. (1995) Biochemistry 34, 724-730.
30. Street, A. G. & Mayo, S. L. (1999) Proc. Natl. Acad. Sci. USA 96, 9074-9076.
31. Spillantini, M. G., Murrell, J. R., Goedert, M., Farlow, M. R., Klug, A. & Ghetti, B. (1998) Neuron 21, 955-958.
32. Hutton, M., Lendon, C. L., Rizzu, P., Baker, M., Froelich, S., Houlden, H., Pickering-Brown, S., Chakraverty, S., Isaacs, A., Grover, A., et al. (1998) Nature (London) 393, 702-705.
33. Clark, L. N., Poorkaj, P., Wszolek, Z., Geschwind, D. H., Nasreddine, Z. S., Miller, B., Li, D., Payami, H., Awert, F., Markopoulou, K., Andreadis, A., et al. (1998) Am. J. Pathol. 153, 1359-1363.
34. Hasegawa, M., Crowther, R. A., Jakes, R. & Goedert, M. (1997) J. Biol. Chem. 272, 33118-33124.
35. Schneider, A., Biernat, J., von Bergen, M., Mandelkow, E. & Mandelkow, E. M. (1999) Biochemistry 38, 3549-3558.
36. Spillantini, M. G., Crowther, R. A., Kamphorst, W., Heutink, P. & van Swieten, J. C. (1998) Am. J. Pathol. 153, 1359-1363.
37. Poorkaj, P., Bird, T. D., Wijsman, E., Nemens, E., Garruto, R. M., Anderson, L., Andreadis, A., Wiederholt, W. C., Raskind, M. & Schellenberg, G. D. (1998) Ann. Neurol. 43, 815-825.
38. Goedert, M., Jakes, R. & Crowther, R. A. (1999) FEBS Lett. 450, 306-311.
39. Nacharaju, P., Lewis, J., Easson, C., Yen, S., Hackett, J., Hutton, M. & Yen, S. H. (1999) FEBS Lett. 447, 195-199.