Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-β peptide exposure: Involvement of Src family protein kinases

Journal of Neuroscience

Volumn 22, Issue 1, 2002, Pages 10-20

  Williamson, Ritchie ^a   Scales, Timothy ^a   Clark, Bruce R ^a   Gibb, Graham ^a   Hugh Reynolds, C ^a   Kellie, Stuart ^b   Bird, Ian N ^b   Varndell, Ian M ^c   Sheppard, Paul W ^c   Everall, Ian ^a   Anderton, Brian H ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b Yamanouchi Research Institute   (United Kingdom)

^c Affiniti Research Products Limited   (United Kingdom)

Author keywords

Alzheimer's disease; Amyloid peptide; Cortical neurons; ERK2; FAK; Fyn; MAP2c; Tau; Tyrosine phosphorylation

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 5 (4 CHLOROPHENYL) 7 (TERT BUTYL)PYRAZOL(3,4 DEXTRO)PYRAMIDE; AMYLOID BETA PROTEIN; CASPASE; CYTOPLASM PROTEIN; CYTOSKELETON PROTEIN; FOCAL ADHESION KINASE; MICROTUBULE ASSOCIATED PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; NERVE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; TAU PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL VIABILITY; CONTROLLED STUDY; DEGENERATIVE DISEASE; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; RAT; WESTERN BLOTTING;

EID: 0036138048     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-01-00010.2002     Document Type: Article

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