Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 19, 2005, Pages 6990-6995

  Noble, Wendy ^a   Planel, Emmanuel ^a   Zehr, Cindy ^b   Olm, Vicki ^a   Meyerson, Jordana ^a   Suleman, Farhana ^a   Gaynor, Kate ^a   Wang, Lili ^a   LaFrancois, John ^a   Feinstein, Boris ^a   Burns, Mark ^a   Krishnamurthy, Pavan ^a   Wen, Yi ^a   Bhat, Ratan ^c   Lewis, Jada ^b   Dickson, Dennis ^b   Duff, Karen ^a  

^a NEW YORK UNIVERSITY   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Alzheimer's disease; Neurofibrillary tangles; Phosphorylation; Tau protein

Indexed keywords

AR A 014418; EPITOPE; GLYCOGEN SYNTHASE KINASE 3; LITHIUM CHLORIDE; N (4 METHOXYBENZYL) N' (5 NITRO 1,3 THIAZOL 2 YL)UREA; PHOSPHATASE; PHOSPHOTRANSFERASE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ADOLESCENT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE OVEREXPRESSION; IN VIVO STUDY; MOUSE; NERVE DEGENERATION; NERVE FIBER DEGENERATION; NEUROFIBRILLARY TANGLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; TAUOPATHY; TRANSGENIC MOUSE;

ANIMALS; DISEASE PROGRESSION; ENZYME INHIBITORS; EPITOPES; GLYCOGEN SYNTHASE KINASE 3; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LITHIUM; LITHIUM CHLORIDE; MICE; MICE, TRANSGENIC; NEURODEGENERATIVE DISEASES; NEURONS; PHOSPHORYLATION; TAU PROTEINS; TAUOPATHIES;

MUS MUSCULUS;

EID: 21044449225     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500466102     Document Type: Article

References (43)

1. Friedhoff, P., von Bergen, M., Mandelkow, E. M. & Mandelkow, E. (2000) Biochim. Biophys. Acta 1502, 122-132.
2. Grundke-Iqbal, I., Iqbal, K., Tung, Y. C., Quinlan, M., Wisniewski, H. M. & Binder, L. I. (1986) Proc. Natl. Acad. Sci. USA 83, 4913-4917.
3. Weaver, C. L., Espinoza, M., Kress, Y. & Davies, P. (2000) Neurobiol Aging 21, 719-727.
4. Buee, L., Bussiere, T., Buee-Scherrer, V., Delacourte, A. & Hof, P. R. (2000) Brain Res. Brain. Res. Rev. 33, 95-130.
5. Cruz, J. C. & Tsai, L. H. (2004) Curr. Opin. Neurobiol. 14, 390-394.
6. Planel, E., Sun, X. & Takashima, A. (2002) Drug Dev. Res. 56, 491-510.
7. Hanger, D. P., Hughes, K., Woodgett, J. R., Brion, J. P. & Anderton, B. H. (1992) Neurosci. Lett. 147, 58-62.
8. Woodgett, J. R. (1990) EMBO J. 9, 2431-2438.
9. Wagner, U., Utton, M., Gallo, J. M. & Miller, C. C. (1996) J. Cell Sci. 109, 1537-1543.
10. Lovestone, S., Hartley, C. L., Pearce, J. & Anderton, B. H. (1996) Neuroscience 73, 1145-1157.
11. Lucas, J. J., Hernandez, F., Gomez-Ramon, P., Moran, M. A., Hen, R. & Avila, J. (2001) EMBO J. 20, 27-39.
12. Sato, S., Tatebayashi, Y., Akagi, T., Chui, D. H., Murayama, M., Miyasaka, T., Planel, E., Tanemura, K., Sun, X., Hashikawa, T., et al. (2002) J. Biol. Chem. 277, 42060-42065.
13. Ishizawa, T., Sahara, N., Ishiguro, K., Kersh, J., McGowan, E., Lewis, J., Hutton, M., Dickson, D. W. & Yen, S. H. (2003) Am. J. Pathol. 163, 1057-1067.
14. Noble, W., Olm, V., Takata, K., Casey, E., Mary, O., Meyerson, J., Gaynor, K., LaFrancois, J., Wang, L., Kondo, T., et al. (2003) Neuron 38, 555-565.
15. Pei, J. J., Tanaka, T., Tung, Y. C., Braak, E., Iqbal, K. & Grundke-Iqbal, I. (1997) J. Neuropathol. Exp. Neurol 56, 70-78.
16. Pei, J. J., Braak, E., Braak, H., Grundke-Iqbal, I., Iqbal, K., Winblad, B. & Cowburn, R. F. (1999) J. Neuropathol. Exp. Neurol. 58, 1010-1019.
17. Phiel, C. J. & Klein, P. S. (2001) Annu. Rev. Pharmacol. Toxicol. 41, 789-813.
18. Chalecka-Franaszek, E. & Chuang, D. M. (1999) Proc. Natl. Acad. Sci. USA 96, 8745-8750.
19. Zhang, F., Phiel, C. J., Spece, L., Gurvich, N. & Klein, P. S. (2003) J. Biol. Chem. 278, 33067-33077.
20. Hong, M., Chen, D. C., Klein, P. S. & Lee, V. M. (1997) J. Biol. Chem. 272, 25326-25332.
21. Munoz-Montano, J. R., Moreno, F. J., Avila, J. & Diaz-Nido, J. (1997) FEBS Lett. 411, 183-188.
22. Takahashi, M., Yasutake, K. & Tomizawa, K. (1999) J. Neurochem. 73, 2073-2083.
23. Perez, M., Hernandez, F., Lim, F., Diaz-Nido, J. & Avila, J. (2003) J. Alzheimers Dis. 5, 301-308.
24. Mudher, A., Shepherd, D., Newman, T. A., Mildren, P., Jukes, J. P., Squire, A., Mears, A., Berg, S., MacKay, D., Asuni, A. A., et al. (2004) Mol. Psychiatry 9, 522-530.
25. Phiel, C. J., Wilson, C. A., Lee, V. M. & Klein, P. S. (2003) Nature 423, 435-439.
26. Lewis, J., McGowan, E., Rockwood, J., Melrose, H., Nacharaju, P., Van Slegtenhorst, M., Gwinn-Hardy, K., Paul Murphy, M., Baker, M., Yu, X., et al. (2000) Nat. Genet. 25, 402-405.
27. Bhat, R., Xue, Y., Berg, S., Hellberg, S., Ormo, M., Nilsson, Y., Radesater, A. C., Jerning, E., Markgren, P. O., Borgegard, T., et al. (2003) J. Biol Chem. 278, 45937-45945.
28. de Silva, R., Lashley, T., Gibb, G., Hanger, D., Hope, A., Reid, A., Bandopadhyay, R., Utton, M., Strand, C., Jowett, T., et al. (2003) Neuropathol. Appl Neurobiol. 29, 288-302.
29. Planel, E., Yasutake, K., Fujita, S. C. & Ishiguro, K. (2001) J. Biol. Chem. 276, 34298-34306.
30. Greenberg, S. G. & Davies, P. (1990) Proc. Natl. Acad. Sci. USA 87, 5827-5831.
31. Sheenan, D. C. & Hrapchak, B. B. (1980) Theory and Practice of Histotechnology (Battelle, Columbus, OH).
32. Zehr, C., Lewis, J., McGowan, E., Crook, J., Lin, W. L., Godwin, K., Knight, J., Dickson, D. W. & Hutton, M. (2004) Neurobiol. Dis. 15, 553-562.
33. Marcus, W. L. (1994) J. Environ. Pathol. Toxicol. Oncol. 13, 73-79.
34. Ryves, W. J. & Harwood, A. J. (2001) Biochem. Biophys. Res. Commun. 280, 720-725.
35. Hernandez, F., Perez, M., Lucas, J. J., Mata, A. M., Bhat, R. & Avila, J. (2004) J. Biol. Chem. 279, 3801-3806.
36. Janke, C., Beck, M., Stahl, T., Holzer, M., Brauer, K., Bigl, V. & Arendt, T. (1999) Brain Res. Mol. Brain Res. 68, 119-128.
37. Lewis, J., Dickson, D. W., Lin, W. L., Chisholm, L., Corral, A., Jones, G., Yen, S. H., Sahara, N., Skipper, L., Yager, D., et al. (2001) Science 293, 1487-1491.
38. Davies, S. P., Reddy, H., Caivano, M. & Cohen, P. (2000) Biochem. J. 351, 95-105.
39. Andorfer, C., Kress, Y., Espinoza, M., de Silva, R., Tucker, K. L., Barde, Y. A., Duff, K. & Davies, P. (2003) J. Neurochem. 86, 582-590.
40. Sahara, N., Lewis, J., DeTure, M., McGowan, E., Dickson, D. W., Hutton, M. & Yen, S. H. (2002) J. Neurochem. 83, 1498-1508.
41. Andorfer, C., Acker, C., Kress, Y., Hof, P., Duff, K. & Davies, P. (2005) J. Neurosci., in press.
42. Necula, M. & Kuret, J. (2004) J. Biol. Chem. 279, 49694-49703.
43. Frasier, M. & Wolozin, B. (2004) Exp. Neurol. 187, 235-239.