PI3K signalling in B- and T-lymphocytes: New developments and therapeutic advances

Biochemical Journal

Volumn 442, Issue 3, 2012, Pages 465-481

  So, Lomon ^a,b   Fruman, David A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Autoimmunity; Cancer; Kinase inhibitor; Leukaemia; Lymphocyte; Lymphoma; Phosphoinositide 3 kinase (PI3K)

Indexed keywords

2 (2 DIFLUOROMETHYLBENZIMIDAZOL 1 YL) 4,6 DIMORPHOLINO 1,3,5 TRIAZINE; 2 (6 AMINO 9 PURINYLMETHYL) 5 METHYL 3 (2 METHYLPHENYL) 3H QUINAZOLIN 4 ONE; 5 [5 (4 FLUORO 2 HYDROXYPHENYL)FURFURYLIDENE] 2,4 THIAZOLIDINEDIONE; 9 (1 ANILINOETHYL) 7 METHYL 2 MORPHOLINOPYRIDO[1,2 A]PYRIMIDIN 4 ONE; AMG 319; AS 604850; AZD 6482; BYL 719; CAL 101; CAL 263; GS 1101; INK 1117; IPI 145; PHENMETRAZINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PICTRELISIB; PIK 75; PIK 90; PROTEIN KINASE B; TGX 115; UNCLASSIFIED DRUG; XL 147;

AUTOIMMUNITY; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL MATURATION; CELL TYPE; DRUG EFFICACY; GENE TARGETING; HUMAN; IMMUNE RESPONSE; LEUKEMIA CELL; LYMPHOMA CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; STIMULUS; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL; THYMOCYTE; TUMOR MICROENVIRONMENT;

ANIMALS; B-LYMPHOCYTES; CELL COMMUNICATION; HUMANS; MODELS, BIOLOGICAL; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 84857875585     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20112092     Document Type: Review

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